Cytokine induced metalloproteinase expression and activity does not correlate with focal susceptibility of articular cartilage to degeneration

Osteoarthritis and Cartilage

Volumn 13, Issue 2, 2005, Pages 162-170

  Little, Christopher B ^a   Flannery, C R ^b   Hughes, C E ^c   Goodship, A ^d   Caterson, B ^c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b PFIZER INC   (United States)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

Aggrecanase; Cartilage catabolism; Matrix metalloproteinases

Indexed keywords

AGGRECAN; AGGRECANASE; COLLAGEN; COLLAGENASE 3; CYTOKINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOSAMINOGLYCAN; HYDROXYPROLINE; INTERLEUKIN 1; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; METALLOPROTEINASE; ONCOSTATIN M; RETINOIC ACID; RNA; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE DEGENERATION; COLLAGEN DEGRADATION; COLLAGEN METABOLISM; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MODEL; DISEASE PREDISPOSITION; ENZYME ACTIVITY; EXPLANT; HORSE; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PATHOGENESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; TISSUE CULTURE; WESTERN BLOTTING;

AGGRECANS; ANIMALS; CARTILAGE, ARTICULAR; COLLAGEN; CULTURE MEDIA, SERUM-FREE; CYTOKINES; EXTRACELLULAR MATRIX PROTEINS; FORELIMB; GLYCOSAMINOGLYCANS; GROWTH INHIBITORS; HORSES; HYDROXYPROLINE; INTERLEUKIN-1; KERATOLYTIC AGENTS; LECTINS, C-TYPE; MATRIX METALLOPROTEINASES; METALLOPROTEASES; ONCOSTATIN M; PEPTIDES; PROTEOGLYCANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TISSUE CULTURE TECHNIQUES; TRETINOIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 13544258903     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2004.10.014     Document Type: Article

References (46)

1. B. Caterson C.R. Flannery C.E. Hughes C.B. Little Mechanisms involved in cartilage proteoglycan catabolism Matrix Biol 19 2000 333-344
2. J. Schlaak I. Pfers K. Meyer Zum Buschenfelde E. Marker-Hermann Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies Clin Exp Rheumatol 14 1996 155-162
3. G. Partsch G. Steiner B. Leeb A. Dunky H. Broll J. Smolen Highly increased levels of tumor necrosis factor-alpha and other proinflammatory cytokines in psoriatic arthritis synovial fluid J Rheumatol 24 1997 518-523
4. T. Horiuchi T. Yoshida Y. Koshihara H. Sakamoto H. Kanai S. Yamamoto et al. The increase of parathyroid hormone-related peptide and cytokine levels in synovial fluid of elderly rheumatoid arthritis and osteoarthritis Endocr J 46 1999 643-649
5. C. Elson F. Mortuza M. Perry M. Warnock G. Webb C. Westacott Cytokines and focal loss of cartilage in osteoarthritis Br J Rheumatol 37 1998 106-107
6. L. Tetlow D. Adlam D. Woolley Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: Associations with degenerative changes Arthritis Rheum 44 2001 585-594
7. C. Westacott R. Atkins P. Dieppe C. Elson Tumor necrosis factor-alpha receptor expression on chondrocytes isolated from human articular cartilage J Rheumatol 21 1994 1710-1715
8. G. Webb C. Westacott C. Elson Chondrocyte tumor necrosis factor receptors and focal loss of cartilage in osteoarthritis Osteoarthritis Cartilage 5 1997 427-437
9. J. Martel-Pelletier R. McCollum J. DiBattista M. Faure J. Chin S. Fournier et al. The interleukin-1 receptor in normal and osteoarthritic human articular chondrocytes. Identification as the type I receptor and analysis of binding kinetics and biologic function Arthritis Rheum 35 1992 530-540
10. W. Herzog A. Clark J. Wu Resultant and local loading in models of joint disease Arthritis Rheum 49 2003 239-247
11. G. Grushko R. Schneiderman A. Maroudas Some biochemical and biophysical parameters for the study of the pathogenesis of osteoarthritis: A comparison between the processes of ageing and degeneration in human hip cartilage Connect Tissue Res 19 1989 149-176
12. M. Harman G. Markovich S. Banks W. Hodge Wear patterns on tibial plateaus from varus and valgus osteoarthritic knees Clin Orthop 352 1998 149-158
13. C. Little P. Ghosh Variation in proteoglycan metabolism by articular chondrocytes in different joint regions is determined by post-natal mechanical loading Osteoarthritis Cartilage 5 1997 49-62
14. C. Westacott A. Barakat L. Wood M. Perry P. Neison I. Bisbinas et al. Tumor necrosis factor alpha can contribute to focal loss of cartilage in osteoarthritis Osteoarthritis Cartilage 8 2000 213-221
15. A. Barakat C. Elson C. Westacott Susceptibility to physiological concentrations of IL-1beta varies in cartilage at different anatomical locations on human osteoarthritic knee joints Osteoarthritis Cartilage 10 2002 264-269
16. R. Schneider L. Bramlage A. Gabel L. Barone B. Kantrowitz Incidence, location and classification of 371 third carpal bone fractures in 313 horses Equine Vet J 6 Suppl 1988 33-42
17. L. Bramlage R. Schneider A. Gabel A clinical perspective on lameness originating in the carpus Equine Vet J 6 Suppl 1988 12-18
18. J. Palmer A. Bertone A. Litsky Contact area and pressure distribution changes of the equine third carpal bone during loading Equine Vet J 26 1994 197-202
19. J. Palmer A. Bertone C. Malemud B. Carter R. Papay J. Mansour Site-specific proteoglycan characteristics of third carpal articular cartilage in exercised and nonexercised horses Am J Vet Res 56 1995 1570-1576
20. J. Palmer A. Bertone J. Mansour B. Carter C. Malemud Biomechanical properties of third carpal articular cartilage in exercised and nonexercised horses J Orthop Res 13 1995 854-860
21. C. Little P. Ghosh R. Rose The effect of strenuous versus moderate exercise on the metabolism of proteoglycans in articular cartilage from different weight-bearing regions of the equine third carpal bone Osteoarthritis Cartilage 5 1997 161-172
22. R. Norrdin C. Kawcak B. Capwell C. McIlwraith Subchondral bone failure in an equine model of overload arthrosis Bone 22 1998 133-139
23. H. Brommer P. van Weeren P. Brama A. Barneveld Quantification and age-related distribution of articular cartilage degeneration in the equine fetlock joint Equine Vet J 35 2003 697-701
24. C.B. Little C. Flannery C.E. Hughes J.S. Mort P.J. Roughley C. Dent et al. Aggrecanase versus matrix metalloproteinases in the interglobular domain catabolism of articular cartilage aggrecan in vitro Biochem J 344 1999 61-68
25. T.E. Cawston V.A. Curry C.A. Summers I.M. Clark G.P. Riley P.F. Life et al. The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint Arthritis Rheum 41 1998 1760-1771
26. S. Collier P. Ghosh Evaluation of the effect of antiarthritic drugs on the secretion of proteoglycans by lapine chondrocytes using a novel assay procedure Ann Rheum Dis 48 1989 372-381
27. R.W. Farndale D.J. Buttle A.J. Barret Improved quantitation and discrimination of sulphated glycosaminoglycan by use of dimethylmethylene blue Biochim Biophys Acta 883 1986 173-177
28. A.J. Ellis V.A. Curry T.E. Cawston The prevention of collagen breakdown in bovine nasal cartilage by TIMP-1, TIMP-2 and a low molecular weight synthetic inhibitor Biochem Biophys Res Commun 201 1994 94-101
29. C.E. Hughes B. Caterson A.J. Fosang P.J. Roughley J.S. Mort Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro Biochem J 305 1995 799-804
30. B. Caterson C.E. Hughes P. Roughley J.S. Mort Anabolic and catabolic markers of proteoglycan metabolism in osteoarthritis Acta Orthop Scand 66 Suppl 266 1995 121-124
31. C.R. Flannery C.B. Little B. Caterson Molecular cloning and sequence analysis of the aggrecan interglobular domain from porcine, equine, bovine and ovine cartilage: Comparison of proteinase-susceptible regions and sites of keratan sulfate substitution Matrix Biol 16 1998 507-511
32. I.G. Otterness J.T. Downs C. Lane M.L. Bliven H. Stukenbrok D.N. Scampoli et al. Detection of collagenase-induced damage of collagen by 9A4, a monoclonal C-terminal neoepitope antibody Matrix Biol 18 4 1999 331-341
33. C.R. Flannery C.B. Little B. Caterson C.E. Hughes Effects of culture conditions and exposure to catabolic stimulators (IL-1 and retinoic acid) on the expression of matrix metalloproteinases (MMPs) and disintegrin metalloproteinases (ADAMs) by articular cartilage chondrocytes Matrix Biol 18 1999 225-237
34. S.G. Rees C.R. Flannery C.B. Little C.E. Hughes B. Caterson C.M. Dent Catabolism of aggrecan, decorin and biglycan in tendon Biochem J 350 2000 181-188
35. C. Curtis S. Rees C. Little C. Flannery C. Hughes C. Wilson et al. Pathologic indicators of degradation and inflammation in human osteoarthritic cartilage are abrogated by exposure to n-3 fatty acids Arthritis Rheum 46 2002 1544-1553
36. A. Malfait R. Liu K. Ijiri S. Komiya M. Tortorella Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage J Biol Chem 277 2002 22201-22208
37. G. Bluteau J. Gouttenoire T. Conrozier P. Mathieu E. Vignon M. Richard et al. Differential gene expression analysis in a rabbit model of osteoarthritis induced by anterior cruciate ligament (ACL) section Biorheology 39 2002 247-258
38. B. Bau P. Gebhard J. Haag T. Knorr E. Bartnik T. Aigner Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro Arthritis Rheum 46 2002 2648-2657
39. L. Kevorkian D. Young C. Darrah S. Donell L. Shepstone S. Porter et al. Expression profiling of metalloproteinases and their inhibitors in cartilage Arthritis Rheum 50 2004 131-141
40. P. Koshy C. Lundy A. Rowan S. Porter D. Edwards A. Hogan et al. The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin-1 and oncostatin M: A time-course study using real-time quantitative reverse transcription-polymerase chain reaction Arthritis Rheum 46 2002 961-967
41. G. Gao J. Westling V. Thompson T. Howell P. Gottschall J. Sandy Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation J Biol Chem 277 2002 11034-11041
42. M. Kashiwagi M. Tortorella H. Nagase K. Brew TIMP-3 is a potent inhibitor of ADAM-TS4 (Aggrecanase 1) and ADAM-TS5 (Aggrecanase 2) J Biol Chem 276 2001 12501-12504
43. J. Milner S. Elliott T. Cawston Activation of procollagenases is a key control point in cartilage collagen degradation: Interaction of serine and metalloproteinase pathways Arthritis Rheum 44 2001 2084-2096
44. T. Cawston V. Curry C. Summers I. Clark G. Riley P. Life et al. The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint Arthritis Rheum 41 1998 1760-1771
45. L.D. Kozaci D.J. Buttle A.P. Hollander Degradation of type II collagen, but not proteoglycan, correlates with matrix metalloproteinase activity in cartilage explant cultures Arthritis Rheum 40 1997 164-174
46. C. Little C. Hughes C. Curtis M. Janusz R. Bohne S. Wang-Weigand et al. Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation Matrix Biol 21 2002 271-288