Long intronic GAA repeats causing Friedreich ataxia impede transcription elongation

EMBO Molecular Medicine

Volumn 2, Issue 4, 2010, Pages 120-129

  Punga, Tanel ^a   Bühler, Marc ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

Epigenetics; Friedreich ataxia (FRDA); Heterochromatic gene silencing; Histone modification; Triplet repeat expansion disorder (TRED)

Indexed keywords

FRATAXIN; HISTONE H3; HISTONE H3 LYSINE 9; MESSENGER RNA; RNA POLYMERASE; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; FRIEDREICH ATAXIA; GAA REPEAT; GENE SILENCING; HUMAN; HUMAN CELL; INTRON; LYMPHOBLASTOID CELL LINE; MALE; PRIORITY JOURNAL; PROTEIN METHYLATION; PROTEIN MODIFICATION; RNA SYNTHESIS; TRANSCRIPTION INITIATION; TRINUCLEOTIDE REPEAT;

CELL LINE; FRIEDREICH ATAXIA; HISTONES; HUMANS; INTRONS; IRON-BINDING PROTEINS; METHYLATION; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 77953659252     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201000064     Document Type: Article

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