Increased hematopoietic cells in the mertk-/- mouse peritoneal cavity: A result of augmented migration

Journal of Immunology

Volumn 184, Issue 12, 2010, Pages 6637-6648

  Williams, Julie C ^a   Wagner, Nikki J ^b   Earp, H Shelton ^a   Vilen, Barbara J ^b   Matsushima, Glenn K ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; AUTOANTIBODY; MERTK PROTEIN, MOUSE; ONCOPROTEIN; PROTEIN TYROSINE KINASE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL COUNT; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DENDRITIC CELL; FAMILY; HEMATOPOIETIC CELL; LYMPHOCYTE MIGRATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PERITONEAL CAVITY; PERITONEUM CELL; PHENOTYPE; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; T CELL DEPLETION; T LYMPHOCYTE; TRANSFER CELL; WILD TYPE; ANIMAL; AUTOIMMUNITY; C57BL MOUSE; CELL MOTION; CELL SEPARATION; CYTOLOGY; FLOW CYTOMETRY; IMMUNOLOGY; LEUKOCYTE; METABOLISM; MOUSE MUTANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; AUTOANTIBODIES; AUTOIMMUNITY; B-LYMPHOCYTES; CELL MOVEMENT; CELL SEPARATION; DENDRITIC CELLS; FLOW CYTOMETRY; LEUKOCYTES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PERITONEAL CAVITY; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES;

EID: 77953644519     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902784     Document Type: Article

References (45)

1. Broche, F., and J. M. Tellado. 2001. Defense mechanisms of the peritoneal cavity. Curr. Opin. Crit. Care 7: 105-116.
2. Finlay-Jones, J. J., K. V. Davies, L. P. Sturm, P. A. Kenny, and P. H. Hart. 1999. Inflammatory processes in a murine model of intra-abdominal abscess formation. J. Leukoc. Biol. 66: 583-587.
3. Berland, R., and H. H. Wortis. 2002. Origins and functions of B-1 cells with notes on the role of CD5. Annu. Rev. Immunol. 20: 253-300.
4. Tumang, J. R., W. D. Hastings, C. Bai, and T. L. Rothstein. 2004. Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics. Eur. J. Immunol. 34: 2158-2167.
5. Viau, M., and M. Zouali. 2005. B-lymphocytes, innate immunity, and autoimmunity. Clin. Immunol. 114: 17-26.
6. Hayakawa, K., R. R. Hardy, D. R. Parks, and L. A. Herzenberg. 1983. The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice. J. Exp. Med. 157: 202-218.
7. Cohen, P. L., R. Caricchio, V. Abraham, T. D. Camenisch, J. C. Jennette, R. A. Roubey, H. S. Earp, G. Matsushima, and E. A. Reap. 2002. Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. J. Exp. Med. 196: 135-140.
8. Gohlke, P. R., J. C. Williams, B. J. Vilen, S. R. Dillon, R. Tisch, and G. K. Matsushima. 2009. The receptor tyrosine kinase MerTK regulates dendritic cell production of BAFF. Autoimmunity 42: 183-197.
9. Lu, Q., and G. Lemke. 2001. Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 293: 306-311. (Pubitemid 32694748)
10. Scott, R. S., E. J. McMahon, S. M. Pop, E. A. Reap, R. Caricchio, P. L. Cohen, H. S. Earp, and G. K. Matsushima. 2001. Phagocytosis and clearance of apoptotic cells is mediated by MER. Nature 411: 207-211.
11. Qian, Y., H. Wang, and S. H. Clarke. 2004. Impaired clearance of apoptotic cells induces the activation of autoreactive anti-Sm marginal zone and B-1 B cells. J. Immunol. 172: 625-635.
12. Murakami, M., H. Yoshioka, T. Shirai, T. Tsubata, and T. Honjo. 1995. Prevention of autoimmune symptoms in autoimmune-prone mice by elimination of B-1 cells. Int. Immunol. 7: 877-882.
13. Behrens, E. M., P. Gadue, S. Y. Gong, S. Garrett, P. L. Stein, and P. L. Cohen. 2003. The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity. Eur. J. Immunol. 33: 2160-2167.
14. Caraux, A., Q. Lu, N. Fernandez, S. Riou, J. P. Di Santo, D. H. Raulet, G. Lemke, and C. Roth. 2006. Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases. Nat. Immunol. 7: 747-754.
15. Graham, D. K., G. W. Bowman, T. L. Dawson, W. L. Stanford, H. S. Earp, and H. R. Snodgrass. 1995. Cloning and developmental expression analysis of the murine c-mer tyrosine kinase. Oncogene 10: 2349-2359.
16. Graham, D. K., D. B. Salzberg, J. Kurtzberg, S. Sather, G. K. Matsushima, A. K. Keating, X. Liang, M. A. Lovell, S. A. Williams, T. L. Dawson, et al. 2006. Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia. Clin. Cancer Res. 12: 2662-2669.
17. Graham, D. K., T. L. Dawson, D. L. Mullaney, H. R. Snodgrass, and H. S. Earp. 1994. Cloning and mRNA expression analysis of a novel human protooncogene, c-mer. Cell Growth Differ. 5: 647-657.
18. Nagata, K., K. Ohashi, T. Nakano, H. Arita, C. Zong, H. Hanafusa, and K. Mizuno. 1996. Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J. Biol. Chem. 271: 30022-30027.
19. Seitz, H. M., T. D. Camenisch, G. Lemke, H. S. Earp, and G. K. Matsushima. 2007. Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells. J. Immunol. 178: 5635-5642.
20. Wallet, M. A., P. Sen, R. R. Flores, Y. Wang, Z. Yi, Y. Huang, C. E. Mathews, H. S. Earp, G. Matsushima, B. Wang, and R. Tisch. 2008. MerTK is required for apoptotic cell-induced T cell tolerance. J. Exp. Med. 205: 219-232.
21. Stitt, T. N., G. Conn, M. Gore, C. Lai, J. Bruno, C. Radziejewski, K. Mattsson, J. Fisher, D. R. Gies, P. F. Jones, et al. 1995. The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases. Cell 80: 661-670.
22. Uehara, H., and E. Shacter. 2008. Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells. J. Immunol. 180: 2522-2530.
23. Wu, Y., S. Singh, M. M. Georgescu, and R. B. Birge. 2005. A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells. J. Cell Sci. 118: 539-553.
24. Camenisch, T. D., B. H. Koller, H. S. Earp, and G. K. Matsushima. 1999. A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock. J. Immunol. 162: 3498-3503.
25. Sen, P., M. A. Wallet, Z. Yi, Y. Huang, M. Henderson, C. E. Mathews, H. S. Earp, G. Matsushima, A. S. Baldwin, Jr., and R. M. Tisch. 2007. Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells. Blood 109: 653-660.
26. Williams, J. C., R. R. Craven, H. S. Earp, T. H. Kawula, and G. K. Matsushima. 2009. TAM receptors are dispensable in the phagocytosis and killing of bacteria. Cell. Immunol. 259: 128-134.
27. Rothlin, C. V., S. Ghosh, E. I. Zuniga, M. B. Oldstone, and G. Lemke. 2007. TAM receptors are pleiotropic inhibitors of the innate immune response. Cell 131: 1124-1136. (Pubitemid 350235020)
28. Gross, J. A., J. Johnston, S. Mudri, R. Enselman, S. R. Dillon, K. Madden, W. Xu, J. Parrish-Novak, D. Foster, C. Lofton-Day, et al. 2000. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 404: 995-999.
29. Khare, S. D., I. Sarosi, X. Z. Xia, S. McCabe, K. Miner, I. Solovyev, N. Hawkins, M. Kelley, D. Chang, G. Van, et al. 2000. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc. Natl. Acad. Sci. USA 97: 3370-3375.
30. Mackay, F., S. A. Woodcock, P. Lawton, C. Ambrose, M. Baetscher, P. Schneider, J. Tschopp, and J. L. Browning. 1999. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190: 1697-1710.
31. Ansel, K. M., R. B. Harris, and J. G. Cyster. 2002. CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity. Immunity 16: 67-76.
32. Hesslein, D. G., S. Y. Yang, and D. G. Schatz. 2006. Origins of peripheral B cells in IL-7 receptor-deficient mice. Mol. Immunol. 43: 326-334.
33. Ito, T., S. Ishikawa, T. Sato, K. Akadegawa, H. Yurino, M. Kitabatake, S. Hontsu, T. Ezaki, H. Kimura, and K. Matsushima. 2004. Defective B1 cell homing to the peritoneal cavity and preferential recruitment of B1 cells in the target organs in a murine model for systemic lupus erythematosus. J. Immunol. 172: 3628-3634. (Pubitemid 38337945)
34. Xu, Z., E. J. Butfiloski, E. S. Sobel, and L. Morel. 2004. Mechanisms of peritoneal B-1a cells accumulation induced by murine lupus susceptibility locus Sle2. J. Immunol. 173: 6050-6058. (Pubitemid 39487760)
35. Shao, W. H., R. A. Eisenberg, and P. L. Cohen. 2008. The Mer receptor tyrosine kinase is required for the loss of B cell tolerance in the chronic graft-versus-host disease model of systemic lupus erythematosus. J. Immunol. 180: 7728-7735.
36. Takahashi, M., Y. Takahashi, K. Takahashi, F. N. Zolotaryov, K. S. Hong, K. Iida, Y. Okimura, H. Kaji, and K. Chihara. 2007. CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity. Biochem. Biophys. Res. Commun. 364: 1037-1042.
37. Wenzel, J., E. Wörenkämper, S. Freutel, S. Henze, O. Haller, T. Bieber, and T. Tüting. 2005. Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosus. J. Pathol. 205: 435-442. (Pubitemid 40361331)
38. Krukemeyer, M. G., J. Moeller, L. Morawietz, B. Rudolph, U. Neumann, T. Theruvath, P. Neuhaus, and V. Krenn. 2004. Description of B lymphocytes and plasma cells, complement, and chemokines/receptors in acute liver allograft rejection. Transplantation 78: 65-70. (Pubitemid 38938285)
39. Yoneyama, H., K. Matsuno, and K. Matsushimaa. 2005. Migration of dendritic cells. Int. J. Hematol. 81: 204-207.
40. Vallin, H., S. Blomberg, G. V. Alm, B. Cederblad, and L. Rönnblom. 1999. Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-alpha) production acting on leucocytes resembling immature dendritic cells. Clin. Exp. Immunol. 115: 196-202.
41. Vallin, H., A. Perers, G. V. Alm, and L. Rönnblom. 1999. Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus. J. Immunol. 163: 6306-6313.
42. Steinmetz, O. M., J. E. Turner, H. J. Paust, M. Lindner, A. Peters, K. Heiss, J. Velden, H. Hopfer, S. Fehr, T. Krieger, et al. 2009. CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis. J. Immunol. 183: 4693-4704.
43. Carvalho, T. L., T. Mota-Santos, A. Cumano, J. Demengeot, and P. Vieira. 2001. Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice. J. Exp. Med. 194: 1141-1150.
44. Luther, S. A., K. M. Ansel, and J. G. Cyster. 2003. Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development. J. Exp. Med. 197: 1191-1198.
45. Kaech, S. M., J. T. Tan, E. J. Wherry, B. T. Konieczny, C. D. Surh, and R. Ahmed. 2003. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 4: 1191-1198.