-
1
-
-
77953577964
-
DNA damage signaling is activated during cancer progression in human colorectal carcinoma
-
Oka K, Tanaka T, Enoki T, Yoshimura K, Ohshima M, Kubo M, et al. DNA damage signaling is activated during cancer progression in human colorectal carcinoma. Cancer Biol Ther 2010; 9:245-51.
-
(2010)
Cancer Biol Ther
, vol.9
, pp. 245-251
-
-
Oka, K.1
Tanaka, T.2
Enoki, T.3
Yoshimura, K.4
Ohshima, M.5
Kubo, M.6
-
2
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J Biol Chem 2001;276:42462-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
3
-
-
0036510055
-
The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
-
Falck J, Petrini JH, Williams BR, Lukas J, Bartek J. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nat Gene 2002; 30:290-4.
-
(2002)
Nat Gene
, vol.30
, pp. 290-294
-
-
Falck, J.1
Petrini, J.H.2
Williams, B.R.3
Lukas, J.4
Bartek, J.5
-
4
-
-
0038418869
-
Chk1 and Chk2 kinases in checkpoint control and cancer
-
DOI 10.1016/S1535-6108(03)00110-7, PII S1535610803001107
-
Bartek J, Lukas J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 2003; 3:421-9. (Pubitemid 38340288)
-
(2003)
Cancer Cell
, vol.3
, Issue.5
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
5
-
-
33748927635
-
Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidants
-
Tanaka T, Halicka HD, Huang X, Traganos F, Darzynkiewicz Z. Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidants. Cell Cycle 2006; 5:1940-5.
-
(2006)
Cell Cycle
, vol.5
, pp. 1940-1945
-
-
Tanaka, T.1
Halicka, H.D.2
Huang, X.3
Traganos, F.4
Darzynkiewicz, Z.5
-
6
-
-
0027109075
-
Cancer. p53, guardian of the genome
-
Lane DP. Cancer. p53, guardian of the genome. Nature 1992; 358:15-6.
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
7
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75:817-25.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
-
9
-
-
0028238213
-
Immediate early up-regulation of bax expression by p53 but not TGFβ1: A paradigm for distinct apoptotic pathways
-
Selvakumaran M, Lin HK, Miyashita T, Wang HG, Krajewski S, Reed JC, et al. Immediate early upregulation of bax expression by p53 but not TGFbeta1: a paradigm for distinct apoptotic pathways. Oncogene 1994; 9:1791-8. (Pubitemid 24163410)
-
(1994)
Oncogene
, vol.9
, Issue.6
, pp. 1791-1798
-
-
Selvakumaran, M.1
Lin, H.-K.2
Miyashita, T.3
Wang, H.G.4
Krajewski, S.5
Reed, J.C.6
Hoffman, B.7
Liebermann, D.8
-
10
-
-
0842300074
-
Microarray analysis of p53 target gene expression patterns in the spleen and thymus in response to ionizing radiation
-
Burns TF, El-Deiry WS. Microarray analysis of p53 target gene expression patterns in the spleen and thymus in response to ionizing radiation. Cancer Biol Ther 2003; 2:431-43.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 431-443
-
-
Burns, T.F.1
El-Deiry, W.S.2
-
11
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, et al. APC mutations occur early during colorectal tumorigenesis. Nature 1992; 359:235-7.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
-
12
-
-
53049087109
-
Genomic and epigenetic instability in colorectal cancer pathogenesis
-
Grady WM, Carethers JM. Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology 2008; 135:1079-99.
-
(2008)
Gastroenterology
, vol.135
, pp. 1079-1099
-
-
Grady, W.M.1
Carethers, J.M.2
-
13
-
-
0015579593
-
Selective inhibition of the cell cycle of cultured human diploid fibroblasts by aminonucleoside of puromycin
-
Studzinski GP, Gierthy JF. Selective inhibition of the cell cycle of cultured human diploid fibroblasts by aminonucleoside of puromycin. J Cell Physiol 1973;81:71-83.
-
(1973)
J Cell Physiol
, vol.81
, pp. 71-83
-
-
Studzinski, G.P.1
Gierthy, J.F.2
-
14
-
-
0015867716
-
Absence of aminonucleoside-sensitive steps in the cell cycle of SV40-transformed human fibroblasts
-
Gierthy JF, Studzinski GP. Absence of aminonucleoside-sensitive steps in the cell cycle of SV40-transformed human fibroblasts. Cancer Res 1973;33:2673-6.
-
(1973)
Cancer Res
, vol.33
, pp. 2673-2676
-
-
Gierthy, J.F.1
Studzinski, G.P.2
-
15
-
-
0026501878
-
Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes
-
Bruno S, Ardelt B, Skierski JS, Traganos F, Darzynkiewicz Z. Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes. Cancer Res 1992; 52:470-3.
-
(1992)
Cancer Res
, vol.52
, pp. 470-473
-
-
Bruno, S.1
Ardelt, B.2
Skierski, J.S.3
Traganos, F.4
Darzynkiewicz, Z.5
-
16
-
-
0012177733
-
Cyclotherapy: Protection of normal cells and unshielding of cancer cells
-
Blagosklonny MV, Darzynkiewicz Z. Cyclotherapy: protection of normal cells and unshielding of cancer cells. Cell Cycle 2002; 1:375-82.
-
(2002)
Cell Cycle
, vol.1
, pp. 375-382
-
-
Blagosklonny, M.V.1
Darzynkiewicz, Z.2
-
17
-
-
36949005417
-
DNA damage signalling guards against activated oncogenes and tumour progression
-
DOI 10.1038/sj.onc.1210881, PII 1210881
-
Bartek J, Bartkova J, Lukas J. DNA damage signalling guards against activated oncogenes and tumour progression. Oncogene 2007; 26:7773-9. (Pubitemid 350242463)
-
(2007)
Oncogene
, vol.26
, Issue.56
, pp. 7773-7779
-
-
Bartek, J.1
Bartkova, J.2
Lukas, J.3
-
18
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
DOI 10.1126/science.1140735
-
Halazonetis TD, Gorgoulis VG, Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008; 319:1352-5. (Pubitemid 351354863)
-
(2008)
Science
, vol.319
, Issue.5868
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
19
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova J, Horejsi Z, Koed K, Kramer A, Tort F, Zieger K, et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005; 434:864-70.
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zieger, K.6
-
20
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005; 434:907-13.
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.V.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
-
21
-
-
33750032892
-
CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage
-
Huang H, Regan KM, Lou Z, Chen J, Tindall DJ. CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage. Science 2006;314:294-7.
-
(2006)
Science
, vol.314
, pp. 294-297
-
-
Huang, H.1
Regan, K.M.2
Lou, Z.3
Chen, J.4
Tindall, D.J.5
-
22
-
-
67650688146
-
Targeting the DNA damage response in cancer
-
Ljungman M. Targeting the DNA damage response in cancer. Chem Rev 2009; 109:2929-50.
-
(2009)
Chem Rev
, vol.109
, pp. 2929-2950
-
-
Ljungman, M.1
-
23
-
-
77954992253
-
Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid and silibinin on proliferation and apoptosis in acute myeloid leukemia cells
-
In press
-
Pesakhov S, Khanin M, Studzinski GP, Danilenko M. Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid and silibinin on proliferation and apoptosis in acute myeloid leukemia cells. Nutr Cancer; In press.
-
Nutr Cancer
-
-
Pesakhov, S.1
Khanin, M.2
Studzinski, G.P.3
Danilenko, M.4
-
24
-
-
0030925565
-
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
-
Baskaran R, Wood LD, Whitaker LL, Canman CE, Morgan SE, Xu Y, et al. Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature 1997; 387:516-9.
-
(1997)
Nature
, vol.387
, pp. 516-519
-
-
Baskaran, R.1
Wood, L.D.2
Whitaker, L.L.3
Canman, C.E.4
Morgan, S.E.5
Xu, Y.6
-
25
-
-
0033600234
-
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
-
Gong JG, Costanzo A, Yang HQ, Melino G, Kaelin WG Jr, Levrero M, et al. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature 1999; 399:806-9.
-
(1999)
Nature
, vol.399
, pp. 806-809
-
-
Gong, J.G.1
Costanzo, A.2
Yang, H.Q.3
Melino, G.4
Kaelin Jr., W.G.5
Levrero, M.6
-
26
-
-
0033600235
-
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
-
Yuan ZM, Shioya H, Ishiko T, Sun X, Gu J, Huang YY, et al. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature 1999; 399:814-7.
-
(1999)
Nature
, vol.399
, pp. 814-817
-
-
Yuan, Z.M.1
Shioya, H.2
Ishiko, T.3
Sun, X.4
Gu, J.5
Huang, Y.Y.6
|