Characterization of 4-methyl-2-oxo-1,2-dihydroquinolin-6-yl acetate as an effective antiplatelet agent

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 11, 2010, Pages 4085-4094

  Priya, Nivedita ^a   Gupta, Anjali ^b   Chand, Karam ^b   Singh, Prabhjot ^a   Kathuria, Abha ^b   Raj, Hanumantharao G ^a   Parmar, Virinder S ^b   Sharma, Sunil K ^b  

^a UNIVERSITY OF DELHI   (India)

^b UNIVERSITY OF DELHI   (India)

Author keywords

Antiplatelet agents; Cox 1; Platelet CRTAase; Quinolin 2 ones

Indexed keywords

4 METHYL 2 OXO 1,2 DIHYDROQUINOLIN 6 YL ACETATE; ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; ARACHIDONIC ACID; CYCLOOXYGENASE 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; THROMBOXANE A2; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME SUBSTRATE; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; RAT; SYNTHESIS; THROMBOCYTE AGGREGATION;

ACETATES; ACETYLTRANSFERASES; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; DOWN-REGULATION; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THROMBOXANE A2;

EID: 77953582019     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.04.011     Document Type: Article

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