Acetoxy drug: Protein transacetylase catalyzed activation of human platelet nitric oxide synthase by polyphenolic peracetates

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 2, 2006, Pages 575-583

  Khurana, Pulkit ^a   Kumari, Ranju ^a   Vohra, Parag ^a   Kumar, Ajit ^a   Seema, ^a   Gupta, Garima ^a   Raj, Hanumantharao G ^a   Dwarakanath, Bilikere S ^b   Parmar, Virinder S ^c   Saluja, Daman ^d   Bose, Mridula ^a   Vij, Anjana ^e   Chaudhary, Nabo K ^b   Adhikari, Jawahar S ^b   Tyagi, Yogesh K ^a   Kohli, Ekta ^a  

^a UNIVERSITY OF DELHI   (India)

^b INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

^c UNIVERSITY OF DELHI   (India)

^d UNIVERSITY OF DELHI   (India)

^e DEFENCE INSTITUTE OF PHYSIOLOGY AND ALLIED SCIENCES   (India)

Author keywords

Nitric oxide; Nitric oxide synthase; Platelet aggregation; Polyphenolic peracetate; Protein acetylation; Transacetylase

Indexed keywords

1 ACETOXYXANTHONE; 7 ACETOXY 3 ACETYL 2 METHYLCHROMONE; 7 ACETOXY 4 METHYLCOUMARIN; 7 ACETOXY 4 METHYLTHIOCUMARIN; 7,8 DIACETOXY 4 METHYLCOUMARIN; 7,8 DIHYDROXY 4 METHYLCOUMARIN; ACYLTRANSFERASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; PERACETIC ACID; POLYPHENOL DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; NORMAL HUMAN; PROTEIN DOMAIN; THROMBOCYTE; THROMBOCYTE AGGREGATION;

ACETATES; ACETYLATION; ACYLTRANSFERASES; BLOOD PLATELETS; BLOTTING, WESTERN; CATALYSIS; CYTOCHROMES C; ENZYME ACTIVATION; FLAVONOIDS; HUMANS; MICROSCOPY, CONFOCAL; NITRIC OXIDE SYNTHASE; PHENOLS;

EID: 28844440477     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.08.044     Document Type: Article

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