Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 9: Comparison of acetoxy 4-methylcoumarins and other polyphenolic acetates reveal the specificity to acetoxy drug: Protein transacetylase for pyran carbonyl group in proximity to the oxygen heteroatom

Bioorganic and Medicinal Chemistry

Volumn 10, Issue 12, 2002, Pages 4103-4111

  Singh, Ishwar ^a   Kohli, Ekta ^b   Raj, Hanumantharao G ^b   Gyanda, Kapil ^a   Jain, Sapan K ^a   Tyagi, Yogesh K ^b   Gupta, Garima ^b   Kumari, Ranju ^b   Kumar, Ajit ^b   Pal, Giridhari ^b   Prasad, Ashok K ^a   Rastogi, Ramesh C ^a   Olsen, Carl E ^c   Jain, Subhash C ^a   Parmar, Virinder S ^a  

^a UNIVERSITY OF DELHI   (India)

^b UNIVERSITY OF DELHI   (India)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

7 ACETOXY 3,4 DIHYDRO 2,2 DIMETHYLBENZOPYRAN; ACETIC ACID DERIVATIVE; ACYLTRANSFERASE; AFLATOXIN B1; BENZOPYRAN DERIVATIVE; CARBONYL DERIVATIVE; CATECHIN; COUMARIN DERIVATIVE; DNA; FLAVONOID; FUNCTIONAL GROUP; KETONE DERIVATIVE; LIVER ENZYME; OXYGEN; POLYPHENOL DERIVATIVE; PYRAN DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL TISSUE; ARTICLE; ATOM; CATALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; IN VITRO STUDY; LIVER MICROSOME; MALE; MODULATION; NONHUMAN; RAT;

ACETATES; ACETYLTRANSFERASES; ANIMALS; COUMARINS; FLAVONOIDS; MALE; MICROSOMES, LIVER; MOLECULAR STRUCTURE; NADH DEHYDROGENASE; PHENOLS; POLYMERS; PYRANS; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0036975801     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00257-2     Document Type: Article

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