-
1
-
-
0032478506
-
Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing
-
Tacke, R., Tohyama, M., Ogawa, S. and Manley, J.L. (1998) Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing. Cell, 93, 139-148.
-
(1998)
Cell
, vol.93
, pp. 139-148
-
-
Tacke, R.1
Tohyama, M.2
Ogawa, S.3
Manley, J.L.4
-
2
-
-
0031010564
-
Molecular cloning of htra2-beta-1 and htra2-beta-2, two human homologs of tra-2 generated by alternative splicing
-
Beil, B., Screaton, G. and Stamm, S. (1997) Molecular cloning of htra2-beta-1 and htra2-beta-2, two human homologs of tra-2 generated by alternative splicing. DNA Cell. Biol., 16, 679-690.
-
(1997)
DNA Cell. Biol.
, vol.16
, pp. 679-690
-
-
Beil, B.1
Screaton, G.2
Stamm, S.3
-
3
-
-
0032569991
-
A sequence-specific splicing activator, tra2beta, is up-regulated in response to nerve injury
-
Kiryu-Seo, S., Matsuo, N., Wanaka, A., Ogawa, S., Tohyama, M. and Kiyama, H. (1998) A sequence-specific splicing activator, tra2beta, is up-regulated in response to nerve injury. Brain Res. Mol. Brain Res., 62, 220-223.
-
(1998)
Brain Res. Mol. Brain Res.
, vol.62
, pp. 220-223
-
-
Kiryu-Seo, S.1
Matsuo, N.2
Wanaka, A.3
Ogawa, S.4
Tohyama, M.5
Kiyama, H.6
-
4
-
-
0033009241
-
Activity-dependent regulation of alternative splicing patterns in the rat brain
-
Daoud, R., Da Penha Berzaghi, M., Siedler, F., Hubener, M. and Stamm, S. (1999) Activity-dependent regulation of alternative splicing patterns in the rat brain. Eur. J. Neurosci., 11, 788-802.
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 788-802
-
-
Daoud, R.1
Da Penha Berzaghi, M.2
Siedler, F.3
Hubener, M.4
Stamm, S.5
-
5
-
-
0035003275
-
Expression of a novel RNA-splicing factor, RA301/Tra2beta, in vascular lesions and its role in smooth muscle cell proliferation
-
Tsukamoto, Y., Matsuo, N., Ozawa, K., Hori, O., Higashi, T., Nishizaki, J., Tohnai, N., Nagata, I., Kawano, K., Yutani, C. et al. (2001) Expression of a novel RNA-splicing factor, RA301/Tra2beta, in vascular lesions and its role in smooth muscle cell proliferation. Am. J. Pathol., 158, 1685-1694.
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 1685-1694
-
-
Tsukamoto, Y.1
Matsuo, N.2
Ozawa, K.3
Hori, O.4
Higashi, T.5
Nishizaki, J.6
Tohnai, N.7
Nagata, I.8
Kawano, K.9
Yutani, C.10
-
6
-
-
33646426385
-
Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene
-
Watermann, D.O., Tang, Y., Zur Hausen, A., Jager, M., Stamm, S. and Stickeler, E. (2006) Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene. Cancer Res., 66, 4774-4780.
-
(2006)
Cancer Res.
, vol.66
, pp. 4774-4780
-
-
Watermann, D.O.1
Tang, Y.2
Zur Hausen, A.3
Jager, M.4
Stamm, S.5
Stickeler, E.6
-
7
-
-
0029903184
-
Molecular cloning of a mouse homologue for the Drosophila splicing regulator Tra2
-
Segade, F., Hurle, B., Claudio, E., Ramos, S. and Lazo, P.S. (1996) Molecular cloning of a mouse homologue for the Drosophila splicing regulator Tra2. FEBS Lett., 387, 152-156.
-
(1996)
FEBS Lett.
, vol.387
, pp. 152-156
-
-
Segade, F.1
Hurle, B.2
Claudio, E.3
Ramos, S.4
Lazo, P.S.5
-
8
-
-
12344250822
-
Function of alternative splicing
-
Stamm, S., Ben-Ari, S., Rafalska, I., Tang, Y., Zhang, Z., Toiber, D., Thanaraj, T.A. and Soreq, H. (2005) Function of alternative splicing. Gene, 344, 1-20.
-
(2005)
Gene
, vol.344
, pp. 1-20
-
-
Stamm, S.1
Ben-Ari, S.2
Rafalska, I.3
Tang, Y.4
Zhang, Z.5
Toiber, D.6
Thanaraj, T.A.7
Soreq, H.8
-
9
-
-
1542359466
-
Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA
-
Stoilov, P., Daoud, R., Nayler, O. and Stamm, S. (2004) Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA. Hum. Mol. Genet., 13, 509-524.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 509-524
-
-
Stoilov, P.1
Daoud, R.2
Nayler, O.3
Stamm, S.4
-
10
-
-
9244259694
-
Tra2betal regulates P19 neuronal differentiation and the splicing of FGF-2R and GluR-B minigenes
-
Chen, X., Huang, J., Li, J., Han, Y., Wu, K. and Xu, P. (2004) Tra2betal regulates P19 neuronal differentiation and the splicing of FGF-2R and GluR-B minigenes. Cell Biol. Int., 28, 791-799.
-
(2004)
Cell Biol. Int.
, vol.28
, pp. 791-799
-
-
Chen, X.1
Huang, J.2
Li, J.3
Han, Y.4
Wu, K.5
Xu, P.6
-
11
-
-
0033593649
-
Regulation of the neuron-specific exon of clathrin light chain B
-
Stamm, S., Casper, D., Hanson, V. and Helfman, D.M. (1999) Regulation of the neuron-specific exon of clathrin light chain B. Brain Res. Mol. Brain Res., 64, 108-118.
-
(1999)
Brain Res. Mol. Brain Res.
, vol.64
, pp. 108-118
-
-
Stamm, S.1
Casper, D.2
Hanson, V.3
Helfman, D.M.4
-
12
-
-
54049149076
-
Tra2beta as a novel mediator of vascular smooth muscle diversification
-
Shukla, S. and Fisher, S.A. (2008) Tra2beta as a novel mediator of vascular smooth muscle diversification. Circ. Res., 103, 485-492.
-
(2008)
Circ. Res.
, vol.103
, pp. 485-492
-
-
Shukla, S.1
Fisher, S.A.2
-
13
-
-
26444575502
-
Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon
-
Venables, J.P., Bourgeois, C.F., Dalgliesh, C., Kister, L., Stevenin, J. and Elliott, D.J. (2005) Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon. Hum. Mol. Genet., 14, 2289-2303.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 2289-2303
-
-
Venables, J.P.1
Bourgeois, C.F.2
Dalgliesh, C.3
Kister, L.4
Stevenin, J.5
Elliott, D.J.6
-
14
-
-
0034701246
-
RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing
-
Venables, J.P., Elliott, D.J., Makarova, O.V., Makarov, E.M., Cooke, H.J. and Eperon, I.C. (2000) RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing. Hum. Mol. Genet., 9, 685-694.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 685-694
-
-
Venables, J.P.1
Elliott, D.J.2
Makarova, O.V.3
Makarov, E.M.4
Cooke, H.J.5
Eperon, I.C.6
-
15
-
-
0038819945
-
Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta
-
Jiang, Z., Tang, H., Havlioglu, N., Zhang, X., Stamm, S., Yan, R. and Wu, J.Y. (2003) Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta. J. Biol. Chem., 278, 18997-19007.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18997-19007
-
-
Jiang, Z.1
Tang, H.2
Havlioglu, N.3
Zhang, X.4
Stamm, S.5
Yan, R.6
Wu, J.Y.7
-
16
-
-
1542330117
-
Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA
-
Kondo, S., Yamamoto, N., Murakami, T., Okumura, M., Mayeda, A. and Imaizumi, K. (2004) Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA. Genes Cells, 9, 121-130.
-
(2004)
Genes Cells
, vol.9
, pp. 121-130
-
-
Kondo, S.1
Yamamoto, N.2
Murakami, T.3
Okumura, M.4
Mayeda, A.5
Imaizumi, K.6
-
17
-
-
10044270719
-
Restoration of the cystic fibrosis transmembrane conductance regulator function by splicing modulation
-
Nissim-Rafinia, M., Aviram, M., Randell, S.H., Shushi, L., Ozeri, E., Chiba-Falek, O., Eidelman, O., Pollard, H.B., Yankaskas, J.R. and Kerem, B. (2004) Restoration of the cystic fibrosis transmembrane conductance regulator function by splicing modulation. EMBO Rep, 5, 1071-1077
-
(2004)
EMBO Rep.
, vol.5
, pp. 1071-1077
-
-
Nissim-Rafinia, M.1
Aviram, M.2
Randell, S.H.3
Shushi, L.4
Ozeri, E.5
Chiba-Falek, O.6
Eidelman, O.7
Pollard, H.B.8
Yankaskas, J.R.9
Kerem, B.10
-
18
-
-
0035253320
-
Alternative splicing of fibroblast growth factor receptors in human prostate cancer
-
Kwabi-Addo, B., Ropiquet, F., Giri, D. and Ittmann, M. (2001) Alternative splicing of fibroblast growth factor receptors in human prostate cancer. Prostate, 46, 163-172.
-
(2001)
Prostate
, vol.46
, pp. 163-172
-
-
Kwabi-Addo, B.1
Ropiquet, F.2
Giri, D.3
Ittmann, M.4
-
19
-
-
0034662922
-
Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2)
-
Hofmann, Y., Lorson, C.L., Stamm, S., Androphy, E.J. and Wirth, B. (2000) Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2). Proc. Natl Acad. Sci. USA, 97, 9618-9623.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 9618-9623
-
-
Hofmann, Y.1
Lorson, C.L.2
Stamm, S.3
Androphy, E.J.4
Wirth, B.5
-
20
-
-
0037101846
-
hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1
-
Hofmann, Y. and Wirth, B. (2002) hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1. Hum. Mol. Genet., 11, 2037-2049.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2037-2049
-
-
Hofmann, Y.1
Wirth, B.2
-
21
-
-
0028797783
-
Identification and characterization of a spinal muscular atrophy-determining gene
-
Lefebvre, S., Burglen, L., Reboullet, S., Clermont, O., Burlet, P., Viollet, L., Benichou, B., Cruaud, C., Millasseau, P., Zeviani, M. et al. (1995) Identification and characterization of a spinal muscular atrophy-determining gene. Cell, 80, 155-165.
-
(1995)
Cell
, vol.80
, pp. 155-165
-
-
Lefebvre, S.1
Burglen, L.2
Reboullet, S.3
Clermont, O.4
Burlet, P.5
Viollet, L.6
Benichou, B.7
Cruaud, C.8
Millasseau, P.9
Zeviani, M.10
-
22
-
-
0034007548
-
An update of the mutation spectrum of the survival motor neuron gene (SMN1) in autosomal recessive spinal muscular atrophy (SMA)
-
Wirth, B. (2000) An update of the mutation spectrum of the survival motor neuron gene (SMN1) in autosomal recessive spinal muscular atrophy (SMA). Hum. Mutat., 15, 228-237.
-
(2000)
Hum. Mutat.
, vol.15
, pp. 228-237
-
-
Wirth, B.1
-
23
-
-
0343267780
-
Structure and organization of the human survival motor neurone (SMN) gene
-
Burglen, L., Lefebvre, S., Clermont, O., Burlet, P., Viollet, L., Cruaud, C., Munnich, A. and Melki, J. (1996) Structure and organization of the human survival motor neurone (SMN) gene. Genomics, 32, 479-482.
-
(1996)
Genomics
, vol.32
, pp. 479-482
-
-
Burglen, L.1
Lefebvre, S.2
Clermont, O.3
Burlet, P.4
Viollet, L.5
Cruaud, C.6
Munnich, A.7
Melki, J.8
-
24
-
-
0036154959
-
Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy
-
Feldkotter, M., Schwarzer, V., Wirth, R., Wienker, T.F. and Wirth, B. (2002) Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy. Am. J. Hum. Genet., 70, 358-368
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 358-368
-
-
Feldkotter, M.1
Schwarzer, V.2
Wirth, R.3
Wienker, T.F.4
Wirth, B.5
-
25
-
-
0030863569
-
When is a deletion not a deletion? When it is converted
-
Burghes, A.H. (1997) When is a deletion not a deletion? When it is converted. Am. J. Hum. Genet., 61, 9-15.
-
(1997)
Am. J. Hum. Genet.
, vol.61
, pp. 9-15
-
-
Burghes, A.H.1
-
26
-
-
33645743043
-
Mildly affected patients with spinal muscular atrophy are partially protected by an increased SMN2 copy number
-
Wirth, B., Brichta, L., Schrank, B., Lochmuller, H., Blick, S., Baasner, A. and Heller, R. (2006) Mildly affected patients with spinal muscular atrophy are partially protected by an increased SMN2 copy number. Hum. Genet., 119, 422-428.
-
(2006)
Hum. Genet.
, vol.119
, pp. 422-428
-
-
Wirth, B.1
Brichta, L.2
Schrank, B.3
Lochmuller, H.4
Blick, S.5
Baasner, A.6
Heller, R.7
-
27
-
-
0033033434
-
A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy
-
Lorson, C.L., Hahnen, E., Androphy, E.J. and Wirth, B. (1999) A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy. Proc. Natl Acad. Sci. USA, 96, 6307-6311
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 6307-6311
-
-
Lorson, C.L.1
Hahnen, E.2
Androphy, E.J.3
Wirth, B.4
-
28
-
-
0036544654
-
Disruption of an SF2/ ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1
-
Cartegni, L. and Krainer, A.R. (2002) Disruption of an SF2/ ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1. Nat. Genet., 30, 377-384.
-
(2002)
Nat. Genet.
, vol.30
, pp. 377-384
-
-
Cartegni, L.1
Krainer, A.R.2
-
29
-
-
0041665176
-
A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy
-
Kashima, T. and Manley, J.L. (2003) A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy. Nat. Genet., 34, 460-463
-
(2003)
Nat. Genet.
, vol.34
, pp. 460-463
-
-
Kashima, T.1
Manley, J.L.2
-
30
-
-
0036501065
-
SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1
-
Young, P.J., DiDonato, C.J., Hu, D., Kothary, R., Androphy, E.J. and Lorson, C.L. (2002) SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Hum. Mol. Genet., 11, 577-587.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 577-587
-
-
Young, P.J.1
DiDonato, C.J.2
Hu, D.3
Kothary, R.4
Androphy, E.J.5
Lorson, C.L.6
-
31
-
-
57649174592
-
TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing
-
Bose, J.K., Wang, I.F., Hung, L., Tarn, W.Y. and Shen, C.K. (2008) TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing. J. Biol. Chem., 283, 28852-28859.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 28852-28859
-
-
Bose, J.K.1
Wang, I.F.2
Hung, L.3
Tarn, W.Y.4
Shen, C.K.5
-
32
-
-
0141506887
-
Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy
-
Brichta, L., Hofmann, Y., Hahnen, E., Siebzehnrubl, F.A., Raschke, H., Blumcke, I., Eyupoglu, I.Y. and Wirth, B. (2003) Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy. Hum. Mol. Genet., 12, 2481-2489.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2481-2489
-
-
Brichta, L.1
Hofmann, Y.2
Hahnen, E.3
Siebzehnrubl, F.A.4
Raschke, H.5
Blumcke, I.6
Eyupoglu, I.Y.7
Wirth, B.8
-
33
-
-
33744803707
-
In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproate
-
Brichta, L., Holker, I., Haug, K., Klockgether, T. and Wirth, B. (2006) In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproate. Ann. Neurol., 59, 970-975.
-
(2006)
Ann. Neurol.
, vol.59
, pp. 970-975
-
-
Brichta, L.1
Holker, I.2
Haug, K.3
Klockgether, T.4
Wirth, B.5
-
34
-
-
33745686137
-
The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells
-
Riessland, M., Brichta, L., Hahnen, E. and Wirth, B. (2006) The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells. Hum. Genet., 120, 101-110.
-
(2006)
Hum. Genet.
, vol.120
, pp. 101-110
-
-
Riessland, M.1
Brichta, L.2
Hahnen, E.3
Wirth, B.4
-
35
-
-
33749264614
-
Spinal muscular atrophy: from gene to therapy
-
Wirth, B., Brichta, L. and Hahnen, E. (2006) Spinal muscular atrophy: from gene to therapy. Semin. Pediatr. Neurol., 13, 121-131.
-
(2006)
Semin. Pediatr. Neurol.
, vol.13
, pp. 121-131
-
-
Wirth, B.1
Brichta, L.2
Hahnen, E.3
-
36
-
-
0242290062
-
Valproic acid increases SMN levels in spinal muscular atrophy patient cells
-
Sumner, C.J., Huynh, T.N., Markowitz, J.A., Perhac, J.S., Hill, B., Coovert, D.D., Schussler, K., Chen, X., Jarecki, J., Burghes, A.H. et al. (2003) Valproic acid increases SMN levels in spinal muscular atrophy patient cells. Ann. Neurol., 54, 647-654.
-
(2003)
Ann. Neurol.
, vol.54
, pp. 647-654
-
-
Sumner, C.J.1
Huynh, T.N.2
Markowitz, J.A.3
Perhac, J.S.4
Hill, B.5
Coovert, D.D.6
Schussler, K.7
Chen, X.8
Jarecki, J.9
Burghes, A.H.10
-
37
-
-
77952295831
-
SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy
-
doi:10.1093/hmg/ddq023, advance access published February 8, 2010
-
Riessland, M., Ackermann, B., Forster, A., Jakubik, M., Hauke, J., Garbes, L., Fritzsche, I., Mende, Y., Blumcke, I., Hahnen, E. et al. (2010) SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy. Hum. Mol. Genet., doi:10.1093/hmg/ddq023, advance access published February 8, 2010.
-
(2010)
Hum. Mol. Genet.
-
-
Riessland, M.1
Ackermann, B.2
Forster, A.3
Jakubik, M.4
Hauke, J.5
Garbes, L.6
Fritzsche, I.7
Mende, Y.8
Blumcke, I.9
Hahnen, E.10
-
38
-
-
0024328766
-
Sex in flies: the splice of life
-
Baker, B.S. (1989) Sex in flies: the splice of life. Nature, 340, 521-524
-
(1989)
Nature
, vol.340
, pp. 521-524
-
-
Baker, B.S.1
-
39
-
-
0034041160
-
High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP
-
Rodriguez, C.I., Buchholz, F., Galloway, J., Sequerra, R., Kasper, J., Ayala, R., Stewart, A.F. and Dymecki, S.M. (2000) High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP. Nat. Genet., 25, 139-140.
-
(2000)
Nat. Genet.
, vol.25
, pp. 139-140
-
-
Rodriguez, C.I.1
Buchholz, F.2
Galloway, J.3
Sequerra, R.4
Kasper, J.5
Ayala, R.6
Stewart, A.F.7
Dymecki, S.M.8
-
40
-
-
0029566108
-
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
-
Schwenk, F., Baron, U. and Rajewsky, K. (1995) A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res., 23, 5080-5081.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 5080-5081
-
-
Schwenk, F.1
Baron, U.2
Rajewsky, K.3
-
41
-
-
0037007121
-
Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes
-
Peitz, M., Pfannkuche, K., Rajewsky, K. and Edenhofer, F. (2002) Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc. Natl Acad. Sci. USA, 99, 4489-4494.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 4489-4494
-
-
Peitz, M.1
Pfannkuche, K.2
Rajewsky, K.3
Edenhofer, F.4
-
42
-
-
0032769071
-
Complete nucleotide sequence, genomic organization, and promoter analysis of the murine survival motor neuron gene (Smn)
-
DiDonato, C.J., Brun, T. and Simard, L.R. (1999) Complete nucleotide sequence, genomic organization, and promoter analysis of the murine survival motor neuron gene (Smn). Mamm. Genome, 10, 638-641.
-
(1999)
Mamm. Genome.
, vol.10
, pp. 638-641
-
-
DiDonato, C.J.1
Brun, T.2
Simard, L.R.3
-
43
-
-
0030896085
-
Cloning, characterization, and copy number of the murine survival motor neuron gene: homolog of the spinal muscular atrophy-determining gene
-
DiDonato, C.J., Chen, X.N., Noya, D., Korenberg, J.R., Nadeau, J.H. and Simard, L.R. (1997) Cloning, characterization, and copy number of the murine survival motor neuron gene: homolog of the spinal muscular atrophy-determining gene. Genome Res., 7, 339-352.
-
(1997)
Genome Res
, vol.7
, pp. 339-352
-
-
DiDonato, C.J.1
Chen, X.N.2
Noya, D.3
Korenberg, J.R.4
Nadeau, J.H.5
Simard, L.R.6
-
44
-
-
0033180516
-
Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity
-
Arber, S., Han, B., Mendelsohn, M., Smith, M., Jessell, T.M. and Sockanathan, S. (1999) Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron, 23, 659-674.
-
(1999)
Neuron
, vol.23
, pp. 659-674
-
-
Arber, S.1
Han, B.2
Mendelsohn, M.3
Smith, M.4
Jessell, T.M.5
Sockanathan, S.6
-
45
-
-
0033987669
-
A mouse model for spinal muscular atrophy
-
Hsieh-Li, H.M., Chang, J.G., Jong, Y.J., Wu, M.H., Wang, N.M., Tsai, C.H. and Li, H. (2000) A mouse model for spinal muscular atrophy. Nat. Genet., 24, 66-70.
-
(2000)
Nat. Genet.
, vol.24
, pp. 66-70
-
-
Hsieh-Li, H.M.1
Chang, J.G.2
Jong, Y.J.3
Wu, M.H.4
Wang, N.M.5
Tsai, C.H.6
Li, H.7
-
46
-
-
0033765283
-
Animal models of spinal muscular atrophy
-
Monani, U.R., Coovert, D.D. and Burghes, A.H. (2000) Animal models of spinal muscular atrophy. Hum. Mol. Genet., 9, 2451-2457.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2451-2457
-
-
Monani, U.R.1
Coovert, D.D.2
Burghes, A.H.3
-
47
-
-
34447525490
-
Spinal muscular atrophy and therapeutic prospects
-
Wirth, B., Brichta, L. and Hahnen, E. (2006) Spinal muscular atrophy and therapeutic prospects. Prog. Mol. Subcell. Biol., 44, 109-132
-
(2006)
Prog. Mol. Subcell. Biol.
, vol.44
, pp. 109-132
-
-
Wirth, B.1
Brichta, L.2
Hahnen, E.3
-
48
-
-
70350749543
-
LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate
-
Garbes, L., Riessland, M., Holker, I., Heller, R., Hauke, J., Trankle, C., Coras, R., Blumcke, I., Hahnen, E. and Wirth, B. (2009) LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate. Hum. Mol. Genet., 18, 3645-3658.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3645-3658
-
-
Garbes, L.1
Riessland, M.2
Holker, I.3
Heller, R.4
Hauke, J.5
Trankle, C.6
Coras, R.7
Blumcke, I.8
Hahnen, E.9
Wirth, B.10
-
50
-
-
0033607012
-
Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20
-
Jumaa, H., Wei, G. and Nielsen, P.J. (1999) Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20. Curr. Biol., 9, 899-902.
-
(1999)
Curr. Biol.
, vol.9
, pp. 899-902
-
-
Jumaa, H.1
Wei, G.2
Nielsen, P.J.3
-
51
-
-
19944427655
-
ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle
-
Xu, X., Yang, D., Ding, J.H., Wang, W., Chu, P.H., Dalton, N.D., Wang, H.Y., Bermingham, J.R. Jr, Ye, Z., Liu, F. et al. (2005) ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell, 120, 59-72.
-
(2005)
Cell
, vol.120
, pp. 59-72
-
-
Xu, X.1
Yang, D.2
Ding, J.H.3
Wang, W.4
Chu, P.H.5
Dalton, N.D.6
Wang, H.Y.7
Bermingham J.R., Jr.8
Ye, Z.9
Liu, F.10
-
52
-
-
0035106072
-
SC35 plays a role in T cell development and alternative splicing of CD45
-
Wang, H.Y., Xu, X., Ding, J.H., Bermingham, J.R. Jr and Fu, X.D. (2001) SC35 plays a role in T cell development and alternative splicing of CD45. Mol. Cell, 7, 331-342.
-
(2001)
Mol. Cell
, vol.7
, pp. 331-342
-
-
Wang, H.Y.1
Xu, X.2
Ding, J.H.3
Bermingham J.R., Jr.4
Fu, X.D.5
-
53
-
-
0034068281
-
hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability
-
Williamson, D.J., Banik-Maiti, S., DeGregori, J. and Ruley, H.E. (2000) hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability. Mol. Cell. Biol., 20, 4094-4105.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4094-4105
-
-
Williamson, D.J.1
Banik-Maiti, S.2
DeGregori, J.3
Ruley, H.E.4
-
54
-
-
27644592554
-
Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation
-
Lin, S., Xiao, R., Sun, P., Xu, X. and Fu, X.D. (2005) Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation. Mol. Cell, 20, 413-425.
-
(2005)
Mol. Cell
, vol.20
, pp. 413-425
-
-
Lin, S.1
Xiao, R.2
Sun, P.3
Xu, X.4
Fu, X.D.5
-
55
-
-
0035510567
-
Regulation of murine survival motor neuron (Smn) protein levels by modifying Smn exon 7 splicing
-
DiDonato, C.J., Lorson, C.L., De Repentigny, Y., Simard, L., Chartrand, C., Androphy, E.J. and Kothary, R. (2001) Regulation of murine survival motor neuron (Smn) protein levels by modifying Smn exon 7 splicing. Hum. Mol. Genet., 10, 2727-2736.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 2727-2736
-
-
DiDonato, C.J.1
Lorson, C.L.2
De Repentigny, Y.3
Simard, L.4
Chartrand, C.5
Androphy, E.J.6
Kothary, R.7
-
56
-
-
0033983258
-
An exonic enhancer is required for inclusion of an essential exon in the SMA-determining gene SMN
-
Lorson, C.L. and Androphy, E.J. (2000) An exonic enhancer is required for inclusion of an essential exon in the SMA-determining gene SMN. Hum. Mol. Genet., 9, 259-265.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 259-265
-
-
Lorson, C.L.1
Androphy, E.J.2
-
57
-
-
0037388256
-
Bifunctional antisense oligonucleotides provide a trans-acting splicing enhancer that stimulates SMN2 gene expression in patient fibroblasts
-
Skordis, L.A., Dunckley, M.G., Yue, B., Eperon, I.C. and Muntoni, F. (2003) Bifunctional antisense oligonucleotides provide a trans-acting splicing enhancer that stimulates SMN2 gene expression in patient fibroblasts. Proc. Natl Acad. Sci. USA, 100, 4114-4119.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 4114-4119
-
-
Skordis, L.A.1
Dunckley, M.G.2
Yue, B.3
Eperon, I.C.4
Muntoni, F.5
-
58
-
-
0037313165
-
Correction of disease-associated exon skipping by synthetic exon-specific activators
-
Cartegni, L. and Krainer, A.R. (2003) Correction of disease-associated exon skipping by synthetic exon-specific activators. Nat. Struct. Biol., 10, 120-125.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 120-125
-
-
Cartegni, L.1
Krainer, A.R.2
-
59
-
-
58749114204
-
Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation
-
Meyer, K., Marquis, J., Trub, J., Nlend Nlend, R., Verp, S., Ruepp, M.D., Imboden, H., Barde, I., Trono, D. and Schumperli, D. (2009) Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation. Hum. Mol. Genet., 18, 546-555.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 546-555
-
-
Meyer, K.1
Marquis, J.2
Trub, J.3
Nlend Nlend, R.4
Verp, S.5
Ruepp, M.D.6
Imboden, H.7
Barde, I.8
Trono, D.9
Schumperli, D.10
-
60
-
-
0034639645
-
The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(2/2) mice and results in a mouse with spinal muscular atrophy
-
Monani, U.R., Sendtner, M., Coovert, D.D., Parsons, D.W., Andreassi, C., Le, T.T., Jablonka, S., Schrank, B., Rossol, W., Prior, T.W. et al. (2000) The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(2/2) mice and results in a mouse with spinal muscular atrophy. Hum. Mol. Genet., 9, 333-339.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 333-339
-
-
Monani, U.R.1
Sendtner, M.2
Coovert, D.D.3
Parsons, D.W.4
Andreassi, C.5
Le, T.T.6
Jablonka, S.7
Schrank, B.8
Rossol, W.9
Prior, T.W.10
-
61
-
-
39449112660
-
Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria
-
Merkwirth, C., Dargazanli, S., Tatsuta, T., Geimer, S., Lower, B., Wunderlich, F.T., von Kleist-Retzow, J.C., Waisman, A., Westermann, B. and Langer, T. (2008) Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria. Genes Dev., 22, 476-488.
-
(2008)
Genes Dev.
, vol.22
, pp. 476-488
-
-
Merkwirth, C.1
Dargazanli, S.2
Tatsuta, T.3
Geimer, S.4
Lower, B.5
Wunderlich, F.T.6
von Kleist-Retzow, J.C.7
Waisman, A.8
Westermann, B.9
Langer, T.10
-
62
-
-
0036246160
-
Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation
-
Eggan, K., Rode, A., Jentsch, I., Samuel, C., Hennek, T., Tintrup, H., Zevnik, B., Erwin, J., Loring, J., Jackson-Grusby, L. et al. (2002) Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nat. Biotechnol., 20, 455-459.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 455-459
-
-
Eggan, K.1
Rode, A.2
Jentsch, I.3
Samuel, C.4
Hennek, T.5
Tintrup, H.6
Zevnik, B.7
Erwin, J.8
Loring, J.9
Jackson-Grusby, L.10
-
63
-
-
0036359284
-
Cre/loxP recombination system and gene targeting
-
Kuhn, R. and Torres, R.M. (2002) Cre/loxP recombination system and gene targeting. Methods Mol. Biol., 180, 175-204.
-
(2002)
Methods Mol. Biol.
, vol.180
, pp. 175-204
-
-
Kuhn, R.1
Torres, R.M.2
-
64
-
-
0025739379
-
Simplified mammalian DNA isolation procedure
-
Laird, P.W., Zijderveld, A., Linders, K., Rudnicki, M.A., Jaenisch, R. and Berns, A. (1991) Simplified mammalian DNA isolation procedure. Nucleic Acids Res., 19, 4293.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 4293
-
-
Laird, P.W.1
Zijderveld, A.2
Linders, K.3
Rudnicki, M.A.4
Jaenisch, R.5
Berns, A.6
-
65
-
-
0012315579
-
-
3rd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
-
Nagy, A., Gertsenstein, M., Vintersten, K. and Behringer, R. (2003) Manipulating the Mouse Embryo, A Laboratory Manual, 3rd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
-
(2003)
Manipulating the Mouse Embryo, A Laboratory Manual
-
-
Nagy, A.1
Gertsenstein, M.2
Vintersten, K.3
Behringer, R.4
|