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Volumn 8, Issue 4, 2010, Pages 330-335

Mucosal adjuvants

Author keywords

Adjuvant; Mucosal adjuvant; Mucosal immunity; Mucosal vaccine; Toll like receptor; Vaccine

Indexed keywords

ADJUVANT; BACTERIAL TOXIN; CHOLERA VACCINE; ENTEROTOXIN; ESCHERICHIA COLI VACCINE; HEPATITIS B VACCINE; INFLUENZA VACCINE; LIVE VACCINE; LTK 63; NASALFLU; ORAL POLIOMYELITIS VACCINE; PHOSPHORYL LIPID A; ROTAVIRUS VACCINE; TOLL LIKE RECEPTOR 9 AGONIST; TOLL LIKE RECEPTOR AGONIST; TYPHOID VACCINE; UNCLASSIFIED DRUG;

EID: 77953495389     PISSN: 1570162X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016210791208695     Document Type: Article
Times cited : (31)

References (83)
  • 1
    • 33644836224 scopus 로고    scopus 로고
    • Mucosal vaccines: The promise and the challenge
    • Neutra MR, Kozlowski PA. Mucosal vaccines: the promise and the challenge. Nat Rev Immunol 2006; 6: 148-58.
    • (2006) Nat Rev Immunol , vol.6 , pp. 148-158
    • Neutra, M.R.1    Kozlowski, P.A.2
  • 2
    • 48649110421 scopus 로고    scopus 로고
    • Terminology: Nomenclature of mucosa-associated lymphoid tissue
    • Brandtzaeg P, Kiyono H, Pabst R, Russel MW. Terminology: nomenclature of mucosa-associated lymphoid tissue. Mucosal Immunol 2008; 1: 31-7.
    • (2008) Mucosal Immunol , vol.1 , pp. 31-37
    • Brandtzaeg, P.1    Kiyono, H.2    Pabst, R.3    Russel, M.W.4
  • 3
    • 4544258068 scopus 로고    scopus 로고
    • NALT- versus Peyer's-Patch-mediated mucosal immunity
    • Kiyono H, Fukuyama S. NALT- versus Peyer's-Patch-mediated mucosal immunity. Nat Rev 2004; 4: 699-710.
    • (2004) Nat Rev , vol.4 , pp. 699-710
    • Kiyono, H.1    Fukuyama, S.2
  • 5
    • 0030740163 scopus 로고    scopus 로고
    • Nasal lymphoid tissue, intranasal immunization, and compartmentalization of the common mucosal immune system
    • Wu HY, Russel MW. Nasal lymphoid tissue, intranasal immunization, and compartmentalization of the common mucosal immune system. Immunol Res 1997; 16: 187-201.
    • (1997) Immunol Res , vol.16 , pp. 187-201
    • Wu, H.Y.1    Russel, M.W.2
  • 6
    • 33646346587 scopus 로고    scopus 로고
    • + T cells in nasal mucosa-associated lymphoid tissue following intranasal immunization with recombinant Streptococcus gordonii
    • + T cells in nasal mucosa-associated lymphoid tissue following intranasal immunization with recombinant Streptococcus gordonii. Infect Immun 2006; 74: 2760-6.
    • (2006) Infect Immun , vol.74 , pp. 2760-2766
    • Medaglini, D.1    Ciabattini, A.2    Cuppone, A.M.3
  • 7
    • 70350705793 scopus 로고    scopus 로고
    • Adoptive transfer of transgenic T cells to study mucosal adjuvants
    • Pettini E, Ciabattini A, Pozzi G, Medaglini D. Adoptive transfer of transgenic T cells to study mucosal adjuvants. Methods 2009; 49: 340-5.
    • (2009) Methods , vol.49 , pp. 340-345
    • Pettini, E.1    Ciabattini, A.2    Pozzi, G.3    Medaglini, D.4
  • 9
    • 34447099136 scopus 로고    scopus 로고
    • Induction of secretory immunity and memory at mucosal surfaces
    • Brandtzaeg P. Induction of secretory immunity and memory at mucosal surfaces. Vaccine 2007; 25: 5467-84.
    • (2007) Vaccine , vol.25 , pp. 5467-5484
    • Brandtzaeg, P.1
  • 11
    • 0035074535 scopus 로고    scopus 로고
    • Vaccination Strategies for Mucosal Immune Responses
    • Ogra PL, Faden H, Welliver RC. Vaccination Strategies for Mucosal Immune Responses. Clin Microbiol Rev 2001; 14: 430-45.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 430-445
    • Ogra, P.L.1    Faden, H.2    Welliver, R.C.3
  • 12
    • 0036281505 scopus 로고    scopus 로고
    • Humoral immune responses to microbial infections in the genital tract
    • Russel MW, Mestecky J. Humoral immune responses to microbial infections in the genital tract. Microbes Infect 2002; 4: 667-77.
    • (2002) Microbes Infect , vol.4 , pp. 667-677
    • Russel, M.W.1    Mestecky, J.2
  • 13
    • 70349621646 scopus 로고    scopus 로고
    • Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin
    • Lewis DJM, Huo Z, Barnett S, et al. Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin. PLoS ONE 2009; 4: 1-5.
    • (2009) PLoS ONE , vol.4 , pp. 1-5
    • Lewis, D.J.M.1    Huo, Z.2    Barnett, S.3
  • 15
    • 17444394873 scopus 로고    scopus 로고
    • Immunologic uniqueness of the genital tract: Challenge for vaccine development
    • Mestecky J, Moldoveanu Z, Russell MW. Immunologic uniqueness of the genital tract: challenge for vaccine development. Am J Reproduct Immunol 2005; 53: 208-14.
    • (2005) Am J Reproduct Immunol , vol.53 , pp. 208-214
    • Mestecky, J.1    Moldoveanu, Z.2    Russell, M.W.3
  • 16
    • 23344453110 scopus 로고    scopus 로고
    • Innate and adaptive immunity in female genital tract: Cellular responses and interactions
    • Wira CR, Fahey JV, Sentman CL, Pioli PA, Shen L. Innate and adaptive immunity in female genital tract: cellular responses and interactions. Immunol Rev 2005; 206: 306-35.
    • (2005) Immunol Rev , vol.206 , pp. 306-335
    • Wira, C.R.1    Fahey, J.V.2    Sentman, C.L.3    Pioli, P.A.4    Shen, L.5
  • 17
    • 33646744394 scopus 로고    scopus 로고
    • Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes
    • Tengvall S, Lundqvist A, Eisenberg RJ, Cohen GH, Harandi AM. Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes. J Virol 2006; 80: 5283-91.
    • (2006) J Virol , vol.80 , pp. 5283-5291
    • Tengvall, S.1    Lundqvist, A.2    Eisenberg, R.J.3    Cohen, G.H.4    Harandi, A.M.5
  • 19
    • 69249112615 scopus 로고    scopus 로고
    • The mucosal adjuvant effect of alpha-galactosylceramide for induction of protective immunity to sexually transmitted viral infection
    • Lindqvist M, Persson J, Thorn K, Harandi AM. The mucosal adjuvant effect of alpha-galactosylceramide for induction of protective immunity to sexually transmitted viral infection. J Immunol 2009; 182: 6435-43.
    • (2009) J Immunol , vol.182 , pp. 6435-6443
    • Lindqvist, M.1    Persson, J.2    Thorn, K.3    Harandi, A.M.4
  • 20
    • 32144438858 scopus 로고    scopus 로고
    • Mucosal immunization with recombinant MOMP genetically linked with modified cholera toxin confers protection against Chlamydia trachomatis infection
    • Singh SR, Hullet K, Pillai SR, Dennis VA, Oh MK, Scissum-Gunn K. Mucosal immunization with recombinant MOMP genetically linked with modified cholera toxin confers protection against Chlamydia trachomatis infection. Vaccine 2006; 24: 1213-24.
    • (2006) Vaccine , vol.24 , pp. 1213-1224
    • Singh, S.R.1    Hullet, K.2    Pillai, S.R.3    Dennis, V.A.4    Oh, M.K.5    Scissum-Gunn, K.6
  • 21
    • 41049103060 scopus 로고    scopus 로고
    • Rectal immunization generates protective immunity in the female genital tract against herpes simplex virus type 2 infection: Relative importance of myeloid differentiation factor 88
    • Tengvall S, O'Hagan D, Harandi AM. Rectal immunization generates protective immunity in the female genital tract against herpes simplex virus type 2 infection: relative importance of myeloid differentiation factor 88. Antiviral Res 2008; 78: 202-14.
    • (2008) Antiviral Res , vol.78 , pp. 202-214
    • Tengvall, S.1    O'Hagan, D.2    Harandi, A.M.3
  • 22
    • 62249122455 scopus 로고    scopus 로고
    • Rectal and vaginal immunization of mice with human papillomavirus L1 virus-like particles
    • Fraillery D, Zosso N, Nardelli-Haefliger D. Rectal and vaginal immunization of mice with human papillomavirus L1 virus-like particles. Vaccine 2009; 27: 2326-34.
    • (2009) Vaccine , vol.27 , pp. 2326-2334
    • Fraillery, D.1    Zosso, N.2    Nardelli-Haefliger, D.3
  • 23
    • 3843066750 scopus 로고    scopus 로고
    • Intravaginal immunization with viral subunit protein plus CpG oligodeoxynucleotides induces protective immunity against HSV-2
    • Kwant A, Rosenthal KL. Intravaginal immunization with viral subunit protein plus CpG oligodeoxynucleotides induces protective immunity against HSV-2. Vaccine 2004; 22: 3098-104.
    • (2004) Vaccine , vol.22 , pp. 3098-3104
    • Kwant, A.1    Rosenthal, K.L.2
  • 24
    • 23844551922 scopus 로고    scopus 로고
    • Kinetics of local and systemic immune responses after vaginal immunization with recombinant cholera toxin B subunit in humans
    • Wassen L, Jertborn M. Kinetics of local and systemic immune responses after vaginal immunization with recombinant cholera toxin B subunit in humans. Clin Diagn Lab Immunol 2005; 12: 447-52.
    • (2005) Clin Diagn Lab Immunol , vol.12 , pp. 447-452
    • Wassen, L.1    Jertborn, M.2
  • 25
    • 70649099130 scopus 로고    scopus 로고
    • Local cytokine and inflammatory responses to candidate vaginal adjuvants in mice
    • Lindqvist M, Navabi N, Jansson M, et al. Local cytokine and inflammatory responses to candidate vaginal adjuvants in mice. Vaccine 2009; 28: 270-8.
    • (2009) Vaccine , vol.28 , pp. 270-278
    • Lindqvist, M.1    Navabi, N.2    Jansson, M.3
  • 26
    • 40349114404 scopus 로고    scopus 로고
    • Sublingual vaccination with influenza virus protects mice against lethal viral infection
    • Song J, Nguyen HH, Cuburu N, et al. Sublingual vaccination with influenza virus protects mice against lethal viral infection. Proc Natl Acad Sci USA 2008; 105: 1644-9.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 1644-1649
    • Song, J.1    Nguyen, H.H.2    Cuburu, N.3
  • 27
    • 67449119132 scopus 로고    scopus 로고
    • CCR7-CCL19/CCL21- regulated dendritic cells are responsible for effectiveness of sublingual vaccination
    • Song JH, Kim J-I, Kwon H-J, et al. CCR7-CCL19/CCL21- regulated dendritic cells are responsible for effectiveness of sublingual vaccination. J Immunol 2009; 182: 6851-60.
    • (2009) J Immunol , vol.182 , pp. 6851-6860
    • Song, J.H.1    Kim, J.-I.2    Kwon, H.-J.3
  • 29
    • 70350532251 scopus 로고    scopus 로고
    • Strategies for optimizing targeting and delivery of mucosal HIV vaccines
    • Ahlers JD, Belyakov IM. Strategies for optimizing targeting and delivery of mucosal HIV vaccines. Eur J Immunol 2009; 39: 2657-69.
    • (2009) Eur J Immunol , vol.39 , pp. 2657-2669
    • Ahlers, J.D.1    Belyakov, I.M.2
  • 30
    • 0036296053 scopus 로고    scopus 로고
    • Recent advances in vaccine adjuvants
    • Singh M, O'Hagan. Recent advances in vaccine adjuvants. Pharm Res 2002; 19: 715-28.
    • (2002) Pharm Res , vol.19 , pp. 715-728
    • Singh, M.1    O'Hagan2
  • 31
    • 1342268100 scopus 로고    scopus 로고
    • Use of the inactivated influenza vaccine and the risk of Bell's palsy in Switzerland
    • Mutsch M, Zhou W, Rhodes P, et al. Use of the inactivated influenza vaccine and the risk of Bell's palsy in Switzerland. N Engl J Med 2004; 350: 896-903.
    • (2004) N Engl J Med , vol.350 , pp. 896-903
    • Mutsch, M.1    Zhou, W.2    Rhodes, P.3
  • 32
    • 44949230030 scopus 로고    scopus 로고
    • Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: A phase II, randomised, double-blind, placebo-controlled field trial
    • Asturias EJ, Halpern J, Torres OR, et al. Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial. Lancet 2008; 371: 2019-25.
    • (2008) Lancet , vol.371 , pp. 2019-2025
    • Asturias, E.J.1    Halpern, J.2    Torres, O.R.3
  • 33
    • 17644371966 scopus 로고    scopus 로고
    • Mucosal immunity and vaccines
    • Holmgren J, Czerkinsky C. Mucosal immunity and vaccines. Nat Med 2005; 11: 45-53.
    • (2005) Nat Med , vol.11 , pp. 45-53
    • Holmgren, J.1    Czerkinsky, C.2
  • 34
    • 0027992673 scopus 로고
    • A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces 307 neutralizing antibodies against the A subunit
    • Pizza M, Fontana MR, Giuliani MM, et al. A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces 307 neutralizing antibodies against the A subunit. J Exp Med 1994; 180: 2147-53.
    • (1994) J Exp Med , vol.180 , pp. 2147-2153
    • Pizza, M.1    Fontana, M.R.2    Giuliani, M.M.3
  • 35
    • 33646447036 scopus 로고    scopus 로고
    • Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers
    • Stephenson I, Zambon MC, Rudin A, et al. Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers. J Virol 2006; 80: 4962-70.
    • (2006) J Virol , vol.80 , pp. 4962-4970
    • Stephenson, I.1    Zambon, M.C.2    Rudin, A.3
  • 36
    • 38449108512 scopus 로고    scopus 로고
    • The acquired immune response to the mucosal adjuvant LTK63 imprints the mouse lung with a protective signature
    • Tritto E, Muzzi A, Pesce I, et al. The acquired immune response to the mucosal adjuvant LTK63 imprints the mouse lung with a protective signature. J Immunol 2007; 179: 5346-57.
    • (2007) J Immunol , vol.179 , pp. 5346-5357
    • Tritto, E.1    Muzzi, A.2    Pesce, I.3
  • 37
    • 0032489830 scopus 로고    scopus 로고
    • Mucosal adjuvanticity and immunogenicity of LTR72, a novel nutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity
    • Giuliani MM, Del Giudice G, Giannelli V, et al. Mucosal adjuvanticity and immunogenicity of LTR72, a novel nutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity. J Exp Med 1998; 187: 1123-32.
    • (1998) J Exp Med , vol.187 , pp. 1123-1132
    • Giuliani, M.M.1    Del Giudice, G.2    Giannelli, V.3
  • 38
    • 0028985871 scopus 로고
    • Dissociation of Escherichia coli heat- labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
    • Dickinson BL, Clements JD. Dissociation of Escherichia coli heat- labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect Immun 1995; 63: 1617-23.
    • (1995) Infect Immun , vol.63 , pp. 1617-1623
    • Dickinson, B.L.1    Clements, J.D.2
  • 39
    • 74149085715 scopus 로고    scopus 로고
    • Toward the development of a stable, freeze-dried formulation of Helicobacter pylori killed whole cell vaccine adjuvanted with a novel mutant of Escherichia coli heat-labile toxin
    • Summerton NA, Welch RW, Bondoc L, et al. Toward the development of a stable, freeze-dried formulation of Helicobacter pylori killed whole cell vaccine adjuvanted with a novel mutant of Escherichia coli heat-labile toxin. Vaccine 2010; 28(5): 1404-11.
    • (2010) Vaccine , vol.28 , Issue.5 , pp. 1404-1411
    • Summerton, N.A.1    Welch, R.W.2    Bondoc, L.3
  • 40
    • 34447625565 scopus 로고    scopus 로고
    • Intrarectal immunization of mice with VP6 and either LT(R192G) or CTA1-DD as adjuvant protects against fecal rotavirus shedding after EDIM challenge
    • McNeal MM, Basu M, Nean JA, et al. Intrarectal immunization of mice with VP6 and either LT(R192G) or CTA1-DD as adjuvant protects against fecal rotavirus shedding after EDIM challenge. Vaccine 2007; 25: 6224-31.
    • (2007) Vaccine , vol.25 , pp. 6224-6231
    • McNeal, M.M.1    Basu, M.2    Nean, J.A.3
  • 41
    • 58149401439 scopus 로고    scopus 로고
    • CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization
    • Sundling C, Schon K, Morner A, et al. CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization. J Gen Virol 2008; 89: 2954-64.
    • (2008) J Gen Virol , vol.89 , pp. 2954-2964
    • Sundling, C.1    Schon, K.2    Morner, A.3
  • 42
    • 67649743425 scopus 로고    scopus 로고
    • CTA1-DD is an effective adjuvant for targeting anti-chlamydial immunity to the murine genital mucosa
    • Cunningham KA, Carey AJ, Lycke N, Timms P, Beagley KW. CTA1-DD is an effective adjuvant for targeting anti-chlamydial immunity to the murine genital mucosa. J Reprod Immunol 2009; 81: 34-8.
    • (2009) J Reprod Immunol , vol.81 , pp. 34-38
    • Cunningham, K.A.1    Carey, A.J.2    Lycke, N.3    Timms, P.4    Beagley, K.W.5
  • 43
    • 0033557754 scopus 로고    scopus 로고
    • Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity
    • Agren LC, Ekman L, Löwenadler B, Nedrud JG, Lycke NY. Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity. J Immunol 1999; 162: 2432-40.
    • (1999) J Immunol , vol.162 , pp. 2432-2440
    • Agren, L.C.1    Ekman, L.2    Löwenadler, B.3    Nedrud, J.G.4    Lycke, N.Y.5
  • 44
    • 43049157532 scopus 로고    scopus 로고
    • Cholera toxin structure, gene regulation and pathophysiological and immunological aspects
    • Sanchez J, Holmgren J. Cholera toxin structure, gene regulation and pathophysiological and immunological aspects. Cell Mol Life Sci 2008; 65: 1347-60.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 1347-1360
    • Sanchez, J.1    Holmgren, J.2
  • 45
    • 0037218655 scopus 로고    scopus 로고
    • Chimeras of labile toxin one and cholera toxin retain mucosal adjuvanticity and direct Th cell subsets via their B subunit
    • Boyaka PN, Ohmura M, Fujihashi K, et al. Chimeras of labile toxin one and cholera toxin retain mucosal adjuvanticity and direct Th cell subsets via their B subunit. J Immunol 2003; 170: 454-62.
    • (2003) J Immunol , vol.170 , pp. 454-462
    • Boyaka, P.N.1    Ohmura, M.2    Fujihashi, K.3
  • 47
    • 0030940274 scopus 로고    scopus 로고
    • Intranasal vaccination of humans with recombinant cholera toxin B subunit induces systemic and local antibody responses in the upper respiratory tract and the vagina
    • Bergquist C, Johansson EL, Lagergard T, Holmgren J, Rudin A. Intranasal vaccination of humans with recombinant cholera toxin B subunit induces systemic and local antibody responses in the upper respiratory tract and the vagina. Infect Immun 1997; 65: 2676-84.
    • (1997) Infect Immun , vol.65 , pp. 2676-2684
    • Bergquist, C.1    Johansson, E.L.2    Lagergard, T.3    Holmgren, J.4    Rudin, A.5
  • 48
    • 0034991762 scopus 로고    scopus 로고
    • Local and systemic immune responses to rectal administration of recombinant cholera toxin B subunit in humans
    • Jertborn M, Nordström I, Kilander A, Czerkinsky C, Holmgren J. Local and systemic immune responses to rectal administration of recombinant cholera toxin B subunit in humans. Infect Immun 2001; 69: 4125-8.
    • (2001) Infect Immun , vol.69 , pp. 4125-4128
    • Jertborn, M.1    Nordström, I.2    Kilander, A.3    Czerkinsky, C.4    Holmgren, J.5
  • 49
    • 1842571646 scopus 로고    scopus 로고
    • Oral B subunit killed whole-cell cholera vaccines
    • In: Levine MM, editor, New York
    • Holmgren J, Bergquist C. Oral B subunit killed whole-cell cholera vaccines. In: Levine MM, editor. New Generation Vaccines. New York, 2004: 499-510.
    • (2004) New Generation Vaccines , pp. 499-510
    • Holmgren, J.1    Bergquist, C.2
  • 50
  • 51
    • 33645790032 scopus 로고    scopus 로고
    • Novel Immunostimulatoy agent based on CpG oligodeoxynucleotide linked to the nontoxic B subunit of cholera toxin
    • Adamsson J, Lindblad M, Lundqvist A, Kelly DJ, Holmgren J, Harandi AM. Novel Immunostimulatoy agent based on CpG oligodeoxynucleotide linked to the nontoxic B subunit of cholera toxin. J Immunol 2006; 176: 4902-13.
    • (2006) J Immunol , vol.176 , pp. 4902-4913
    • Adamsson, J.1    Lindblad, M.2    Lundqvist, A.3    Kelly, D.J.4    Holmgren, J.5    Harandi, A.M.6
  • 52
    • 42049084684 scopus 로고    scopus 로고
    • The adjuvant effect of CpG oligodeoxynucleotide linked to the non-toxic B subunit of cholera toxin for induction of immunity against H. pylori in mice
    • Nystrom-Asklin J, Adamsson J, Harandi AM. The adjuvant effect of CpG oligodeoxynucleotide linked to the non-toxic B subunit of cholera toxin for induction of immunity against H. pylori in mice. Scand J immunol 2008; 67: 431-40.
    • (2008) Scand J Immunol , vol.67 , pp. 431-440
    • Nystrom-Asklin, J.1    Adamsson, J.2    Harandi, A.M.3
  • 53
    • 61749101130 scopus 로고    scopus 로고
    • CpG oligonuclleotides as adjuvants for vaccines targeting infectious diseases
    • Klinman DM, Klaschik S, Sato T, Tross D. CpG oligonuclleotides as adjuvants for vaccines targeting infectious diseases. Advanced Drug Delivery Rev 2009; 61: 248-55.
    • (2009) Advanced Drug Delivery Rev , vol.61 , pp. 248-255
    • Klinman, D.M.1    Klaschik, S.2    Sato, T.3    Tross, D.4
  • 54
    • 3042725534 scopus 로고    scopus 로고
    • CpG DNA as a potent inducer of mucosal immunity: Implications for immunoprophylaxis and immunotherapy of mucosal infections
    • Harandi AM, Holmgren J. CpG DNA as a potent inducer of mucosal immunity: implications for immunoprophylaxis and immunotherapy of mucosal infections. Curr Opin Investig Drugs 2004; 5: 141-5.
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 141-145
    • Harandi, A.M.1    Holmgren, J.2
  • 55
    • 23844523426 scopus 로고    scopus 로고
    • alpha- Galactosylceramide can act as a nasal vaccine adjuvant inducing protective immune responses against viral infection and tumor
    • Ko SY, Ko HJ, Chang WS, Park SH, Kweon MN. alpha- Galactosylceramide can act as a nasal vaccine adjuvant inducing protective immune responses against viral infection and tumor. J Immunol 2005; 175: 3309-17.
    • (2005) J Immunol , vol.175 , pp. 3309-3317
    • Ko, S.Y.1    Ko, H.J.2    Chang, W.S.3    Park, S.H.4    Kweon, M.N.5
  • 56
    • 33645754276 scopus 로고    scopus 로고
    • Mucosal Immunisation: Adjuvants and Delivery Systems
    • Moyle PM, McGeary RP, Toth B, Toth B. Mucosal Immunisation: Adjuvants and Delivery Systems. Curr Drug Deliv 2004; 1: 385-96.
    • (2004) Curr Drug Deliv , vol.1 , pp. 385-396
    • Moyle, P.M.1    McGeary, R.P.2    Toth, B.3    Toth, B.4
  • 57
    • 77249147827 scopus 로고    scopus 로고
    • Vaccine adjuvanys: A priority for vaccine research
    • Working Group convened by Europrice
    • Harandi AM, Medaglini D, Shattock RJ, Working Group convened by Europrice. Vaccine adjuvanys: A priority for vaccine research. Vaccine 2010; 28: 2363-66.
    • (2010) Vaccine , vol.28 , pp. 2363-2366
    • Harandi, A.M.1    Medaglini, D.2    Shattock, R.J.3
  • 58
    • 64449088278 scopus 로고    scopus 로고
    • The European effort towards the development of mucosal vaccines for poverty-related diseases
    • Medaglini D, Olesen OF, Rappuoli R. The European effort towards the development of mucosal vaccines for poverty-related diseases. Vaccine 2009; 27: 2641-8.
    • (2009) Vaccine , vol.27 , pp. 2641-2648
    • Medaglini, D.1    Olesen, O.F.2    Rappuoli, R.3
  • 59
    • 0034785654 scopus 로고    scopus 로고
    • Papillomavirus pseudovirus: A novel vaccine to induce mucosal and systemic cytotoxic T- lymphocyte responses
    • Shi W, Liu J, Huang Y, Quiao L. Papillomavirus pseudovirus: a novel vaccine to induce mucosal and systemic cytotoxic T- lymphocyte responses. J Virol 2001; 75: 10139-48.
    • (2001) J Virol , vol.75 , pp. 10139-48
    • Shi, W.1    Liu, J.2    Huang, Y.3    Quiao, L.4
  • 60
    • 0034802009 scopus 로고    scopus 로고
    • Recombinant Norwalk virus-like particles administered intranasally to mice induce systemic and mucosal (fecal and vaginal) immune responses
    • Guerrero RA, Ball JM, Krater SS, Pacheco SE, Clements JD, Estes MK. Recombinant Norwalk virus-like particles administered intranasally to mice induce systemic and mucosal (fecal and vaginal) immune responses. J Virol 2001; 75: 9713-22.
    • (2001) J Virol , vol.75 , pp. 9713-9722
    • Guerrero, R.A.1    Ball, J.M.2    Krater, S.S.3    Pacheco, S.E.4    Clements, J.D.5    Estes, M.K.6
  • 61
    • 0036058509 scopus 로고    scopus 로고
    • Chimeric recombinant hepatitis E virus-like particles as an oral vaccine vehicle presenting foreign epitopes
    • Niikura M, Takamura S, Kim G, et al. Chimeric recombinant hepatitis E virus-like particles as an oral vaccine vehicle presenting foreign epitopes. Virology 2002; 293: 273-80.
    • (2002) Virology , vol.293 , pp. 273-280
    • Niikura, M.1    Takamura, S.2    Kim, G.3
  • 62
    • 33751217419 scopus 로고    scopus 로고
    • Delivery systems and adjuvants for oral vaccines
    • Lavelle EC, O'Hagan DT. Delivery systems and adjuvants for oral vaccines. Expert Opin Drug Deliv 2006; 3: 747-62.
    • (2006) Expert Opin Drug Deliv , vol.3 , pp. 747-762
    • Lavelle, E.C.1    O'Hagan, D.T.2
  • 63
    • 77953484009 scopus 로고    scopus 로고
    • CAF01 liposomes as a mucosal vaccine adjuvant: In vitro and in vivo investigations
    • Epub ahead of print
    • Christensen D, Foged C, Rosenkrands I, et al. CAF01 liposomes as a mucosal vaccine adjuvant: In vitro and in vivo investigations. Int J Pharm 2009; Epub ahead of print.
    • (2009) Int J Pharm
    • Christensen, D.1    Foged, C.2    Rosenkrands, I.3
  • 64
    • 33645218586 scopus 로고    scopus 로고
    • Proteliposome-derived Cochleate as an immunomodulator for nasal vaccine
    • Perez O, Bracho G, Lastre M, et al. Proteliposome-derived Cochleate as an immunomodulator for nasal vaccine. Vaccine 2006; 24: 53-3.
    • (2006) Vaccine , vol.24 , pp. 53-53
    • Perez, O.1    Bracho, G.2    Lastre, M.3
  • 65
    • 74249104167 scopus 로고    scopus 로고
    • Intranasal immunization with a proteoliposome-derived cochleate containing recombinant gD protein confers protective immunity against genital herpes in mice
    • Del Campo J, Lindquist L, Cuello M, et al. Intranasal immunization with a proteoliposome-derived cochleate containing recombinant gD protein confers protective immunity against genital herpes in mice. Vaccine 2010; 28: 1193-200.
    • (2010) Vaccine , vol.28 , pp. 1193-1200
    • Del Campo, J.1    Lindquist, L.2    Cuello, M.3
  • 66
    • 0035178074 scopus 로고    scopus 로고
    • Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans
    • Johansson E-L, Wassen L, Holmgren J, Jertborn M, Rudin A. Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans. Infect Immun 2001; 69: 7481-6.
    • (2001) Infect Immun , vol.69 , pp. 7481-7486
    • Johansson, E.-L.1    Wassen, L.2    Holmgren, J.3    Jertborn, M.4    Rudin, A.5
  • 67
    • 0037992894 scopus 로고    scopus 로고
    • Mutants of the Escherichia coli heat-labile enterotoxin as safe and strong adjuvants for intranasal delivery of vaccines
    • Peppoloni S, Ruggiero G, Contorni M, Morandi M, Pizza M. Mutants of the Escherichia coli heat-labile enterotoxin as safe and strong adjuvants for intranasal delivery of vaccines. Expert Rev Vaccines 2003; 2: 285-93.
    • (2003) Expert Rev Vaccines , vol.2 , pp. 285-293
    • Peppoloni, S.1    Ruggiero, G.2    Contorni, M.3    Morandi, M.4    Pizza, M.5
  • 68
    • 49149092626 scopus 로고    scopus 로고
    • Randomized clinical trial assessing the safety and immunogenicity of oral microencapsulated enterotoxigenic Escherichia coli surface antigen 6 with or without heat-labile enterotoxin with mutation R192G
    • Lapa JA, Sincock SA, Ananthakrishnan M, et al. Randomized clinical trial assessing the safety and immunogenicity of oral microencapsulated enterotoxigenic Escherichia coli surface antigen 6 with or without heat-labile enterotoxin with mutation R192G. Clin Vaccine Immunol 2008; 15: 1222-8.
    • (2008) Clin Vaccine Immunol , vol.15 , pp. 1222-1228
    • Lapa, J.A.1    Sincock, S.A.2    Ananthakrishnan, M.3
  • 69
    • 1242270653 scopus 로고    scopus 로고
    • Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: Enhancement of Th2 responses and toxin- neutralizing antibodies by formulation with chitosan
    • McNeela EA, Jabbal-Gill I, Illum L, et al. Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: enhancement of Th2 responses and toxin- neutralizing antibodies by formulation with chitosan. Vaccine 2004; 22: 909-14.
    • (2004) Vaccine , vol.22 , pp. 909-914
    • McNeela, E.A.1    Jabbal-Gill, I.2    Illum, L.3
  • 70
    • 28444471597 scopus 로고    scopus 로고
    • Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal immunoglobulin A in volunteers by nasal insufflations of the Neisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed with chitosan
    • Huo Z, Sinha R, Mc Neela EA, et al. Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal immunoglobulin A in volunteers by nasal insufflations of the Neisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed with chitosan. Infect Immun 2005; 73: 8256-65.
    • (2005) Infect Immun , vol.73 , pp. 8256-8265
    • Huo, Z.1    Sinha, R.2    McNeela, E.A.3
  • 71
    • 29044438039 scopus 로고    scopus 로고
    • Intranasal administration of a proteosome-influenza vaccine is well-tolerated and induces serum and nasal secretion influenza antibodies in healthy human subjects
    • Treanor J, Nolan C, O'Brien DP, et al. Intranasal administration of a proteosome-influenza vaccine is well-tolerated and induces serum and nasal secretion influenza antibodies in healthy human subjects. Vaccine 2006; 24: 254-62.
    • (2006) Vaccine , vol.24 , pp. 254-262
    • Treanor, J.1    Nolan, C.2    O'Brien, D.P.3
  • 72
    • 1342268107 scopus 로고    scopus 로고
    • Nasal vaccination, Escherichia coli enterotoxin, and Bell's palsy
    • Couch RB. Nasal vaccination, Escherichia coli enterotoxin, and Bell's palsy. N Engl J Med 2004; 350: 860-1.
    • (2004) N Engl J Med , vol.350 , pp. 860-861
    • Couch, R.B.1
  • 73
    • 44449088495 scopus 로고    scopus 로고
    • Dynavax trial halted
    • DeFrancesco L. Dynavax trial halted. Nat Biotechnol 2008; 26: 484.
    • (2008) Nat Biotechnol , vol.26 , pp. 484
    • Defrancesco, L.1
  • 74
    • 58149112511 scopus 로고    scopus 로고
    • Analysis of adverse events of potential autoimmune aetiology in a large integrated safety database of AS04 adjuvant vaccines
    • Verstraeten T, Descamps D, David MP, et al. Analysis of adverse events of potential autoimmune aetiology in a large integrated safety database of AS04 adjuvant vaccines. Vaccine 2008; 26: 6630-8.
    • (2008) Vaccine , vol.26 , pp. 6630-6638
    • Verstraeten, T.1    Descamps, D.2    David, M.P.3
  • 75
    • 0031159818 scopus 로고    scopus 로고
    • Oral immunization with simian immunodeficiency virus p55gag and cholera toxin elicits both mucosal IgA and systemic IgG immune responses in nonhuman primates
    • Kubota M, Miller C, Imaoka K, Kawabat S, Fujihashi K, MJR, Kiyono H. Oral immunization with simian immunodeficiency virus p55gag and cholera toxin elicits both mucosal IgA and systemic IgG immune responses in nonhuman primates. J Immunol 1997; 158: 5321-9.
    • (1997) J Immunol , vol.158 , pp. 5321-5329
    • Kubota, M.1    Miller, C.2    Imaoka, K.3    Kawabat, S.4    Fujihashi, K.5    M, J.R.6    Kiyono, H.7
  • 76
    • 0032402228 scopus 로고    scopus 로고
    • Nasal immunization of nonhuman primates with simian immunodeficiency virus p55gag and cholera toxin adjuvant induces Th1/Th2 help for virus-specific immune responses in reproductive tissues
    • Imaoka K, Miller CJ, Kubota M, et al. Nasal immunization of nonhuman primates with simian immunodeficiency virus p55gag and cholera toxin adjuvant induces Th1/Th2 help for virus-specific immune responses in reproductive tissues. J Immunol 1998; 161: 5952-8.
    • (1998) J Immunol , vol.161 , pp. 5952-5958
    • Imaoka, K.1    Miller, C.J.2    Kubota, M.3
  • 77
    • 76249115228 scopus 로고    scopus 로고
    • Sublingual immunization with nonreplicating antigens induces antibody- forming cells and cytotoxic T cells in the female genital tract mucosa and protects against genital papillomavirus infection
    • Cuburu N, Kweon MN, Hervouet C, et al. Sublingual immunization with nonreplicating antigens induces antibody- forming cells and cytotoxic T cells in the female genital tract mucosa and protects against genital papillomavirus infection. J Immunol 2009; 183: 7851-9.
    • (2009) J Immunol , vol.183 , pp. 7851-7859
    • Cuburu, N.1    Kweon, M.N.2    Hervouet, C.3
  • 78
    • 40349114404 scopus 로고    scopus 로고
    • Sublingual vaccination with influenza virus protects mice against lethal viral infection
    • Song JH, Nguyen HH, Cuburu N, et al. Sublingual vaccination with influenza virus protects mice against lethal viral infection. Proc Natl Acad Sci USA 2008; 105: 1644-9.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 1644-1649
    • Song, J.H.1    Nguyen, H.H.2    Cuburu, N.3
  • 79
    • 0029008132 scopus 로고
    • A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins
    • Roberts M, Bacon A, Rappuoli R, et al. A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins. Infect Immun 1995; 63: 2100-8.
    • (1995) Infect Immun , vol.63 , pp. 2100-2108
    • Roberts, M.1    Bacon, A.2    Rappuoli, R.3
  • 80
    • 4143140916 scopus 로고    scopus 로고
    • Non-toxic Stx derivatives from Escherichia coli possess adjuvant activity for mucosal immunity
    • Ohmura-Hoshino M, Yamamoto M, Yuki Y, Takeda Y, Kiyono H. Non-toxic Stx derivatives from Escherichia coli possess adjuvant activity for mucosal immunity. Vaccine 2004; 22: 3751-61.
    • (2004) Vaccine , vol.22 , pp. 3751-3761
    • Ohmura-Hoshino, M.1    Yamamoto, M.2    Yuki, Y.3    Takeda, Y.4    Kiyono, H.5
  • 81
    • 2942573369 scopus 로고    scopus 로고
    • Molecular adjuvants for mucosal immunity
    • Toka FN, Pack CD, Rouse BT. Molecular adjuvants for mucosal immunity. Immunol Rev 2004; 199: 100-12.
    • (2004) Immunol Rev , vol.199 , pp. 100-112
    • Toka, F.N.1    Pack, C.D.2    Rouse, B.T.3
  • 82
    • 22244486625 scopus 로고    scopus 로고
    • Effective nasal influenza vaccine delivery using chitosan
    • Read RC, Naylor SC, Potter CW, et al. Effective nasal influenza vaccine delivery using chitosan. Vaccine 2005; 23: 4367-74.
    • (2005) Vaccine , vol.23 , pp. 4367-4374
    • Read, R.C.1    Naylor, S.C.2    Potter, C.W.3
  • 83
    • 0035888201 scopus 로고    scopus 로고
    • Pre-clinical and clinical investigation of the safety of a novel adjuvant for intranasal immunization
    • Glueck R. Pre-clinical and clinical investigation of the safety of a novel adjuvant for intranasal immunization. Vaccine 2001; 20: 42-4.
    • (2001) Vaccine , vol.20 , pp. 42-44
    • Glueck, R.1


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