Effectiveness of mass oral cholera vaccination in Beira, Mozambique

New England Journal of Medicine

Volumn 352, Issue 8, 2005, Pages 757-767

  Lucas, Marcelino E S ^a   Deen, Jacqueline L ^b   Von Seidlein, Lorenz ^b   Wang, Xuan Yi ^b   Ampuero, Julia ^d   Puri, Mahesh ^b   Ali, Mohammad ^b   Ansaruzzaman, M ^c   Amos, Juvenaldo ^a   Macuamule, Arminda ^a   Cavailler, Philippe ^d   Guerin, Philippe J ^d   Mahoudeau, Claude ^e   Kahozi Sangwa, Pierre ^f   Chaignat, Claire Lise ^g   Barreto, Avertino ^a   Songane, Francisco F ^a   Clemens, John D ^b  

^a MINISTRY OF HEALTH   (Mozambique)

^b International Vaccine Institute   (South Korea)

^c ICDDR B Centre for Health and Population Research   (Bangladesh)

^d EPICENTRE   (France)

^e MÉDECINS SANS FRONTIÈRES   (Switzerland)

^f WORLD HEALTH ORGANIZATION   (Switzerland)

^g Natl Inst Child Hlth/Hum Devmt ^*

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA VACCINE; CHOLERA TOXIN; CHOLERA TOXIN, B SUBUNIT (50 64); CHOLERA TOXIN, B SUBUNIT (50-64); INACTIVATED VACCINE; PEPTIDE FRAGMENT;

ADULT; AFRICA; ARTICLE; BACTERIUM CULTURE; CASE CONTROL STUDY; CHILD; CHOLERA; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DRUG EFFICACY; FEMALE; HEALTH CARE POLICY; HEALTH PROGRAM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MASS IMMUNIZATION; MOZAMBIQUE; PREVALENCE; PRIORITY JOURNAL; SEROPREVALENCE; TREATMENT OUTCOME; WORLD HEALTH ORGANIZATION; ADOLESCENT; FEASIBILITY STUDY; HEALTH SURVEY; ISOLATION AND PURIFICATION; MIDDLE AGED; PRESCHOOL CHILD; PREVENTIVE HEALTH SERVICE; STATISTICAL MODEL; VIBRIO CHOLERAE; VIROLOGY;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHOLERA; CHOLERA TOXIN; CHOLERA VACCINES; DIARRHEA; FEASIBILITY STUDIES; FEMALE; HIV INFECTIONS; HUMANS; IMMUNIZATION PROGRAMS; LOGISTIC MODELS; MALE; MIDDLE AGED; MOZAMBIQUE; PEPTIDE FRAGMENTS; POPULATION SURVEILLANCE; TREATMENT OUTCOME; VACCINES, INACTIVATED; VIBRIO CHOLERAE;

EID: 13844321245     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMoa043323     Document Type: Article

References (23)

1. Report on cholera control programme in Mozambique. Geneva: World Health Organization Global Task Force on Cholera Control, June 2003.
2. Clemens JD, Sack DA, Harris JR, et al. Field trial of oral cholera vaccines in Bangladesh. Lancet 1986;2:124-7.
3. Clemens JD, Sack DA, Harris JR, et al. Field trial of oral cholera vaccines in Bangladesh: results from three-year follow-up. Lancet 1990;335:270-3.
4. Sanchez JL, Vasquez B, Begue RE, et al. Protective efficacy of oral whole-cell/recombinant-B-subunit cholera vaccine in Peruvian military recruits. Lancet 1994;344:1273-6.
5. Holmgren J, Berquist C. Oral B subunit-killed whole-cell cholera vaccine. In: Levine MM, Kaper JB, Rappuoli R, Liu MA, Good MF, eds. New generation vaccines. 3rd ed. New York: Marcel Dekker, 2004:499-509.
6. Cholera vaccines: a new public health tool? Report of a WHO meeting, 10-11 December 2002. Geneva: World Health Organization Global Task Force on Cholera Control, 2004. (WHO/CDS/CPE/ZFK/2004.5.)
7. World Health Organization. Mozambique: summary country profile for HIV/ AIDS treatment scale-up, 2004: the 3 by 5 Initiative. (Accessed February 3, 2005, at http://www.who.int/3by5/en/Mozambique.pdf.)
8. A manual for the treatment of diarrhoea. 2nd ed. rev. Geneva: World Health Organization Programme for the Control of Diarrhoeal Diseases, 1990. (WHO/CDD/SER/80.2.)
9. Monsur KA. A highly selective gelatin-taurocholate-tellurite medium for the isolation of Vibrio cholerae. Trans R Soc Trop Med Hyg 1961;55:440-2.
10. Ansaruzzaman M, Bhuiyan NA, Nair GB, et al. Cholera in Mozambique, variant of Vibrio cholerae. Emerg Infect Dis 2004;10:2057-59.
11. Orenstein WA, Bernier RH, Dondero T, et al. Field evaluation of vaccine efficacy. Bull World Health Organ 1985;63:1055-68.
12. Shapiro ED. Case control studies of the effectiveness of vaccines: vilidity and assessment of potential bias. Pediatr Infect Dis J 2004;23:127-31.
13. Peltola H, Siitonen A, Kyronseppa H, et al. Prevention of travellers' diarrhoea by oral B-subunit/whole-cell cholera vaccine. Lancet 1991;338:1285-9.
14. Clemens JD, Sack DA, Harris JR, et al. Cross-protection by B subunit-whole cell cholera vaccine against diarrhea associated with heat-labile toxin-producing enterotoxigenic Escherichia coli: results of a large-scale field trial. J Infect Dis 1988;158:372-7.
15. Schlesselman JJ. Case-control studies: design, conduct, analysis. New York: Oxford University Press, 1982:69-103.
16. Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR. A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol 1996;49:1373-9.
17. Clemens J, Brenner R, Rao M, Tafari N, Lowe C. Evaluating new vaccines for developing countries: efficacy or effectiveness? JAMA 1996;275:390-7.
18. Legros D, Paquet C, Perea W, et al. Mass vaccination with a two-dose oral cholera vaccine in a refugee camp. Bull World Health Organ 1999;77:837-42.
19. Dorlencourt F, Legros D, Paquet C, Neira M, Ivanoff B, Le Saout E. Effectiveness of mass vaccination with WC/rBS cholera vaccine during an epidemic in Adjumani district, Uganda. Bull World Health Organ 1999;77:949-50.
20. Eriksson K, Kilander A, Hagberg L, Norkrans G, Holmgren J, Czerkinsky C. Intestinal antibody responses to oral vaccination in HIV-infected individuals. AIDS 1993;7:1087-91.
21. Lewis DJ, Gilks CF, Ojoo S, et al. Immune response following oral administration of cholera toxin B subunit to HIV-1-infected UK and Kenyan subjects. AIDS 1994;8:779-85.
22. Ortigao-de-Sampaio MB, Shattock RJ, Hayes P, et al. Increase in plasma viral load after oral cholera immunization of HIV-infected subjects. AIDS 1998;12:F145-F150.
23. Clemens JD, Sack DA, Harris JR, et al. Breast feeding and the risk of severe cholera in rural Bangladeshi children. Am J Epidemiol 1990;131:400-11.