Oral immunization with simian immunodeficiency virus p55gag and cholera toxin elicits both mucosal IgA and systemic IgG immune responses in nonhuman primates

Journal of Immunology

Volumn 158, Issue 11, 1997, Pages 5321-5329

  Kubota, Mitsuru ^a   Miller, Christopher J ^b   Imaoka, Koichi ^a   Kawabata, Shigetada ^a,d   Fujihashi, Kohtaro ^a   McGhee, Jerry R ^a   Kiyono, Hiroshi ^a,c,e  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Res Inst for Microbial Diseases   (United States)

^d OSAKA UNIVERSITY   (Japan)

^e OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN; GAG PROTEIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; P55 GAG PRECURSOR PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; PROTEIN PRECURSOR; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; IMMUNITY; IMMUNIZATION; IMMUNOLOGY; MACACA; MUCOSAL IMMUNITY; ORAL DRUG ADMINISTRATION; SIMIAN IMMUNODEFICIENCY VIRUS;

ADMINISTRATION, ORAL; ANIMALS; CHOLERA TOXIN; GENE PRODUCTS, GAG; IMMUNITY; IMMUNITY, MUCOSAL; IMMUNIZATION; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MACACA MULATTA; PROTEIN PRECURSORS; RECOMBINANT PROTEINS; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0031159818     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Kiyono, H., C. J. Miller, Y. Lu, T. Lehner, M. Cranage, Y. T. Huang, S. Kawabata, M. Marthas, B. Roberts, J. G. Nedrud, M. E. Lamm, L. Bergmeier, R. Brookes, L. Tao, and J. R. McGhee. 1995. The common mucosal immune system for the reproductive tract: basic principles applied toward an AIDS vaccine. Adv. Drug Delivery Rev. 18:23.
2. Miller, C. J., J. R. McGhee, and M. B. Gardner. 1992. Mucosal immunity, HIV transmission, and AIDS. Lab. Invest. 68:129.
3. Staats, H. F., R. J. Jackson, M. Marinaro, I. Takahashi, H. Kiyono, and J. R. McGhee. 1994. Mucosal immunity to infection with implications for vaccine development. Curr. Opin. Immunol. 6:572.
4. Miller, C. J., N. J. Alexander, S. Sutjipto, A. A. Lackner, A. Genie, A. G. Hendrickx, L. J. Lowenstine, M. Jennings, and P. A. Marx. 1989. Genital mucosal transmission of simian immunodeficiency virus: animal model for heterosexual transmission of human immunodeficiency virus. J. Virol. 63:4277.