메뉴 건너뛰기




Volumn 2, Issue 2, 2010, Pages 61-68

Characterization of human homeodomain-interacting protein kinase 4 (HIPK4) as a unique member of the HIPK family

Author keywords

HIPK family; HIPK4; Kinase; Phosphorylation; Site directed mutagenesis; Sumoylation

Indexed keywords

ASPARTIC ACID; HOMEODOMAIN INTERACTING PROTEIN KINASE 1; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; HOMEODOMAIN INTERACTING PROTEIN KINASE 3; HOMEODOMAIN INTERACTING PROTEIN KINASE 4; LYSINE; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

EID: 77953449809     PISSN: None     EISSN: 19381247     Source Type: Journal    
DOI: 10.4255/mcpharmacol.10.09     Document Type: Article
Times cited : (16)

References (28)
  • 1
    • 0345898928 scopus 로고    scopus 로고
    • Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors
    • 2
    • Kim YH, Choi CY, Lee SJ, et al. Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors. J Biol Chem 1998;2:273:25875-79.
    • (1998) J Biol Chem , vol.273 , pp. 25875-25879
    • Kim, Y.H.1    Choi, C.Y.2    Lee, S.J.3
  • 2
    • 53249124722 scopus 로고    scopus 로고
    • HIPKs: Jack of all trades in basic nuclear activities
    • Rinaldo C, Siepi F, Prodosmo A, et al. HIPKs: Jack of all trades in basic nuclear activities. Biochem Biophysica Acta 2008;2124-29.
    • (2008) Biochem Biophysica Acta , pp. 2124-2129
    • Rinaldo, C.1    Siepi, F.2    Prodosmo, A.3
  • 3
    • 18244379872 scopus 로고    scopus 로고
    • Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
    • D'Orazi G, Cecchinelli B, Bruno T, et al. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat Cell Biol 2002;4:11-9.
    • (2002) Nat Cell Biol , vol.4 , pp. 11-19
    • D'orazi, G.1    Cecchinelli, B.2    Bruno, T.3
  • 4
    • 0036141392 scopus 로고    scopus 로고
    • Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
    • Hofmann TG, Möller A, Sirma H, et al. Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat Cell Biol 2002; 4:1-10.
    • (2002) Nat Cell Biol , vol.4 , pp. 1-10
    • Hofmann, T.G.1    Möller, A.2    Sirma, H.3
  • 5
    • 0034675849 scopus 로고    scopus 로고
    • FIST/HIPK3: A Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation
    • Rochat-Steiner V, Becker K, Micheau O, et al. FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation. J Exp Med 2000;192:1165-74.
    • (2000) J Exp Med , vol.192 , pp. 1165-1174
    • Rochat-Steiner, V.1    Becker, K.2    Micheau, O.3
  • 6
    • 75149167980 scopus 로고    scopus 로고
    • DOC45, a novel DNA damage-regulated nucleocytoplasmic ATPase that is overexpressed in multiple human malignancies
    • Sun H, Luo X, Montalbano J, et al. DOC45, a novel DNA damage-regulated nucleocytoplasmic ATPase that is overexpressed in multiple human malignancies. Mol Cancer Res 2010;8:57-66.
    • (2010) Mol Cancer Res , vol.8 , pp. 57-66
    • Sun, H.1    Luo, X.2    Montalbano, J.3
  • 7
    • 67650555449 scopus 로고    scopus 로고
    • Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation
    • Montalbano J, Lui K, Sheikh MS, et al. Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation. J Biol Chem 2009;284:18129-42.
    • (2009) J Biol Chem , vol.284 , pp. 18129-18142
    • Montalbano, J.1    Lui, K.2    Sheikh, M.S.3
  • 8
    • 51049124339 scopus 로고    scopus 로고
    • Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignancies
    • Corcoran CA, He Q, Ponnusamy S, et al. Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignancies. Mol Cancer Res 2008;6:795-807.
    • (2008) Mol Cancer Res , vol.6 , pp. 795-807
    • Corcoran, C.A.1    He, Q.2    Ponnusamy, S.3
  • 9
    • 28244502271 scopus 로고    scopus 로고
    • Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif and is upregulated in gastrointestinal cancers
    • Luo X, He Q, Huang Y, Sheikh MS. Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif and is upregulated in gastrointestinal cancers. Cancer Res 2005;65:10725-33.
    • (2005) Cancer Res , vol.65 , pp. 10725-10733
    • Luo, X.1    He, Q.2    Huang, Y.3    Sheikh, M.S.4
  • 10
    • 0242551644 scopus 로고    scopus 로고
    • Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation
    • Luo X, Huang Y, Sheikh MS. Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation. Oncogene 2003;22:7247-57.
    • (2003) Oncogene , vol.22 , pp. 7247-7257
    • Luo, X.1    Huang, Y.2    Sheikh, M.S.3
  • 11
    • 42249086969 scopus 로고    scopus 로고
    • Celecoxib and a novel COX-2 inhibitor ON09310 upregulate death receptor 5 expression via GADD153/CHOP
    • He Q, Luo X, Jin W, Huang Y, et al. Celecoxib and a novel COX-2 inhibitor ON09310 upregulate death receptor 5 expression via GADD153/CHOP. Oncogene 2008;27:2656-60.
    • (2008) Oncogene , vol.27 , pp. 2656-2660
    • He, Q.1    Luo, X.2    Jin, W.3    Huang, Y.4
  • 12
    • 36849052501 scopus 로고    scopus 로고
    • Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation
    • Rong R, Jiang LY, Sheikh MS, Huang Y. Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation. Oncogene 2007;26:7700-8.
    • (2007) Oncogene , vol.26 , pp. 7700-7708
    • Rong, R.1    Jiang, L.Y.2    Sheikh, M.S.3    Huang, Y.4
  • 13
    • 75149140546 scopus 로고    scopus 로고
    • Smac deficiency affects endoplasmic reticulum stress-induced apoptosis in human colon cancer cells
    • He Q, Shi J, Jones S, et al. Smac deficiency affects endoplasmic reticulum stress-induced apoptosis in human colon cancer cells. Mol Cell Pharmacol 2009;1:23-28.
    • (2009) Mol Cell Pharmacol , vol.1 , pp. 23-28
    • He, Q.1    Shi, J.2    Jones, S.3
  • 14
    • 75149187497 scopus 로고    scopus 로고
    • Sulindac sulfide differentially induces apoptosis in Smacproficient and -deficient human colon cancer cells
    • Shi J, He Q, An J, Sun H, Huang Y, Sheikh MS. Sulindac sulfide differentially induces apoptosis in Smacproficient and -deficient human colon cancer cells. Mol Cell Pharmacol 2009;1:92-97.
    • (2009) Mol Cell Pharmacol , vol.1 , pp. 92-97
    • Shi, J.1    He, Q.2    An, J.3    Sun, H.4    Huang, Y.5    Sheikh, M.S.6
  • 15
    • 0034523266 scopus 로고    scopus 로고
    • SUMO--nonclassical ubiquitin
    • Melchior, F. SUMO--nonclassical ubiquitin. Annu Rev Cell Dev Biol. 2000;16:591-626.
    • (2000) Annu Rev Cell Dev Biol , vol.16 , pp. 591-626
    • Melchior, F.1
  • 16
    • 0037305847 scopus 로고    scopus 로고
    • Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity
    • Ecsedy JA, Michaelson JS, Leder P. Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity. Mol Cell Biol 2003;23:950-60.
    • (2003) Mol Cell Biol , vol.23 , pp. 950-960
    • Ecsedy, J.A.1    Michaelson, J.S.2    Leder, P.3
  • 17
    • 17644397574 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation
    • Li X, Zhang R, Luo D, et al. Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation. J Biol Chem 2005;280:15061-70.
    • (2005) J Biol Chem , vol.280 , pp. 15061-15070
    • Li, X.1    Zhang, R.2    Luo, D.3
  • 18
    • 36549023049 scopus 로고    scopus 로고
    • Novel homeodomain-interacting protein kinase family member, HIPK4, phosphorylates human p53 at serine 9
    • Arai S, Matsushita A, Du K, Yagi K, Okazaki Y, Kurokawa R. Novel homeodomain-interacting protein kinase family member, HIPK4, phosphorylates human p53 at serine 9. FEBS Lett 2007;581:5649-57.
    • (2007) FEBS Lett , vol.581 , pp. 5649-5657
    • Arai, S.1    Matsushita, A.2    Du, K.3    Yagi, K.4    Okazaki, Y.5    Kurokawa, R.6
  • 19
    • 0033961443 scopus 로고    scopus 로고
    • Role of p53 family members in apoptosis
    • Sheikh MS, Fornace AJ Jr. Role of p53 family members in apoptosis. J Cell Physiol 2000;182:171-81.
    • (2000) J Cell Physiol , vol.182 , pp. 171-181
    • Sheikh, M.S.1    Fornace Jr., A.J.2
  • 20
    • 33947534030 scopus 로고    scopus 로고
    • Lane DP. p53 in health and disease
    • Vousden KH, Lane DP. p53 in health and disease. Nat Rev Mol Cell Biol 2007;8:275-283.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 275-283
    • Vousden, K.H.1
  • 21
    • 0034725644 scopus 로고    scopus 로고
    • Human p53 is phosphorylated on serines 6 and 9 in response to DNA damage-inducing agents
    • Higashimoto Y, Saito S, Tong XH, et al. Human p53 is phosphorylated on serines 6 and 9 in response to DNA damage-inducing agents. J Biol Chem 2000;275:23199-203.
    • (2000) J Biol Chem , vol.275 , pp. 23199-23203
    • Higashimoto, Y.1    Saito, S.2    Tong, X.H.3
  • 22
    • 0037066695 scopus 로고    scopus 로고
    • ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation
    • Saito S, Goodarzi AA, Higashimoto Y, et al. ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation. J Biol Chem 2002;277:12491-4.
    • (2002) J Biol Chem , vol.277 , pp. 12491-12494
    • Saito, S.1    Goodarzi, A.A.2    Higashimoto, Y.3
  • 23
    • 33646757232 scopus 로고    scopus 로고
    • The complexity of p53 stabilization and activation
    • Lavin MF, Gueven N. The complexity of p53 stabilization and activation. Cell Death Differ 2006;13:941-50.
    • (2006) Cell Death Differ , vol.13 , pp. 941-950
    • Lavin, M.F.1    Gueven, N.2
  • 24
  • 25
    • 33645238760 scopus 로고    scopus 로고
    • Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals
    • Isono K, Nemoto K, Li Y, et al. Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol Cell Biol 2006;26:2758-71.
    • (2006) Mol Cell Biol , vol.26 , pp. 2758-2771
    • Isono, K.1    Nemoto, K.2    Li, Y.3
  • 26
    • 23844433285 scopus 로고    scopus 로고
    • Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification
    • Hofmann TG, Jaffray E, Stollberg N, Hay RT, Will H. Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification. J Biol Chem 2005;280:29224-32.
    • (2005) J Biol Chem , vol.280 , pp. 29224-29232
    • Hofmann, T.G.1    Jaffray, E.2    Stollberg, N.3    Hay, R.T.4    Will, H.5
  • 27
    • 17644377920 scopus 로고    scopus 로고
    • Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability
    • Gresko E, Möller A, Roscic A, Schmitz ML. Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability. Biochem Biophys Res Commun 2005;329:1293-9.
    • (2005) Biochem Biophys Res Commun , vol.329 , pp. 1293-1299
    • Gresko, E.1    Möller, A.2    Roscic, A.3    Schmitz, M.L.4
  • 28
    • 0037330454 scopus 로고    scopus 로고
    • The homeodomain-interacting kinase PKM (HIPK-2) modifies ND10 through both its kinase domain and a SUMO-1 interaction motif and alters the posttranslational modification of PML
    • Engelhardt OG, Boutell C, Orr A, Ullrich E, Haller O, Everett RD. The homeodomain-interacting kinase PKM (HIPK-2) modifies ND10 through both its kinase domain and a SUMO-1 interaction motif and alters the posttranslational modification of PML. Exp Cell Res 2003;283:36-50.
    • (2003) Exp Cell Res , vol.283 , pp. 36-50
    • Engelhardt, O.G.1    Boutell, C.2    Orr, A.3    Ullrich, E.4    Haller, O.5    Everett, R.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.