-
3
-
-
0345256634
-
The role of p53 in chemosensitivity and radiosensitivity
-
El-Deiry WS. The role of p53 in chemosensitivity and radiosensitivity. Oncogene 2003;22:7486-95.
-
(2003)
Oncogene
, vol.22
, pp. 7486-7495
-
-
El-Deiry, W.S.1
-
4
-
-
0033961443
-
Role of p53 family members in apoptosis
-
Sheikh MS, Fornace AJ, Jr. Role of p53 family members in apoptosis. J Cell Physiol 2000;182:171-81.
-
(2000)
J Cell Physiol
, vol.182
, pp. 171-181
-
-
Sheikh, M.S.1
Fornace Jr., A.J.2
-
5
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002;2:594-604.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
6
-
-
0035265823
-
PUMA induces the rapid apoptosis of colorectal cancer cells
-
Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol Cell 2001;7:673-82.
-
(2001)
Mol Cell
, vol.7
, pp. 673-682
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
Kinzler, K.W.4
Vogelstein, B.5
-
7
-
-
0035265686
-
PUMA, A novel proapoptotic gene, is induced by p53
-
Nakano K, Vousden KH, PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 2001;7:683-94.
-
(2001)
Mol Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
8
-
-
0035949470
-
Expression of bbc3. A pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals
-
Han J, Flemington C, Houghton AB, et al. Expression of bbc3. a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals. Proc Natl Acad Sci U S A 2001;98:11318-23.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 11318-11323
-
-
Han, J.1
Flemington, C.2
Houghton, A.B.3
-
9
-
-
0037452759
-
PUMA mediates the apoptotic response to p53 in colorectal cancer cells
-
Yu J, Wang Z, Kinzler KW, et al. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc Natl Acad Sci U S A 2003;100:1931-6.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1931-1936
-
-
Yu, J.1
Wang, Z.2
Kinzler, K.W.3
-
10
-
-
0242410719
-
P53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger A, Michalak EM, Coultas L, et al. p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 2003;302:1036-8.
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
-
11
-
-
10744228800
-
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
-
Jeffers JR, Parganas E, Lee Y, et al. Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell 2003;4:321-8.
-
(2003)
Cancer Cell
, vol.4
, pp. 321-328
-
-
Jeffers, J.R.1
Parganas, E.2
Lee, Y.3
-
12
-
-
0042477717
-
Gene expression during ER stress-induced apoptosis in neurons: Induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway
-
Reimertz C, Kogel D, Kami A, Chittenden T, Prehn JH. Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol 2003;162:587-97.
-
(2003)
J Cell Biol
, vol.162
, pp. 587-597
-
-
Reimertz, C.1
Kogel, D.2
Kami, A.3
Chittenden, T.4
Prehn, J.H.5
-
13
-
-
12844266066
-
Identification of a network involved in thapsigargin-induced apoptosis using a library of small interfering RNA expression vectors
-
Futami T, Miyagishi M, Taira K. Identification of a network involved in thapsigargin-induced apoptosis using a library of small interfering RNA expression vectors. J Biol Chem 2005;280:826-31.
-
(2005)
J Biol Chem
, vol.280
, pp. 826-831
-
-
Futami, T.1
Miyagishi, M.2
Taira, K.3
-
14
-
-
27144453741
-
Transcriptional upregulation of PUMA modulates endoplasmic reticulum calcium pool depletion-induced apoptusis via Bax activation
-
Luo X, He Q, Huang Y, Sheikh MS. Transcriptional upregulation of PUMA modulates endoplasmic reticulum calcium pool depletion-induced apoptusis via Bax activation. Cell Death Differ 2005;12:1310-8.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1310-1318
-
-
Luo, X.1
He, Q.2
Huang, Y.3
Sheikh, M.S.4
-
15
-
-
0037138403
-
Calmodulin signaling via the IQ motif
-
Bahler M, Rhoads A. Calmodulin signaling via the IQ motif. FEES Lett 2002;513:107-13.
-
(2002)
FEES Lett
, vol.513
, pp. 107-113
-
-
Bahler, M.1
Rhoads, A.2
-
16
-
-
0035028435
-
2+/CaM-dependent kinases: From activation to function
-
2+/CaM-dependent kinases: from activation to function. Annu Rev Pharmacol Toxicol 2001;41:417-505.
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 417-505
-
-
Hook, S.S.1
Means, A.R.2
-
19
-
-
4544275715
-
2+/calmodulm-dependent protein kinase II produce opposing effects on the affinity of calmodulin for calcium
-
2+/calmodulm-dependent protein kinase II produce opposing effects on the affinity of calmodulin for calcium. J Biol Chem 2004;279:39374-82.
-
(2004)
J Biol Chem
, vol.279
, pp. 39374-39382
-
-
Gaertner, T.R.1
Putkey, J.A.2
Waxham, M.N.3
-
21
-
-
0033453226
-
Identification and classification of p53-regulated genes
-
Yu J, Zhang L, Hwang PM, et al. Identification and classification of p53-regulated genes. Proc Natl Acad Sci U S A 1999;96:14517-22.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 14517-14522
-
-
Yu, J.1
Zhang, L.2
Hwang, P.M.3
-
22
-
-
0035884187
-
Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells
-
Huang Y, He Q, Hiltman MJ, et al. Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells. Cancer Res 2001;61:6918-24.
-
(2001)
Cancer Res
, vol.61
, pp. 6918-6924
-
-
Huang, Y.1
He, Q.2
Hiltman, M.J.3
-
23
-
-
0037026582
-
Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective noivsteroidal anti-inflammatory agent in Bax-deficient cells
-
He Q, Luo X, Huang Y, Sheikh MS. Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective noivsteroidal anti-inflammatory agent in Bax-deficient cells. Oncogene 2002;21:6032-40.
-
(2002)
Oncogene
, vol.21
, pp. 6032-6040
-
-
He, Q.1
Luo, X.2
Huang, Y.3
Sheikh, M.S.4
-
24
-
-
0242551644
-
Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation
-
Luo X, Huang Y, Sheikh MS. Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation. Oncogene 2003;22:7247-57.
-
(2003)
Oncogene
, vol.22
, pp. 7247-7257
-
-
Luo, X.1
Huang, Y.2
Sheikh, M.S.3
-
25
-
-
1242339638
-
Calmodulin binding to the Fas death domain. Regulation by Fas activation
-
Ahn EY, Lim ST, Cook WJ, McDonald JM. Calmodulin binding to the Fas death domain. Regulation by Fas activation. J Biol Chem 2004;279:5661-6.
-
(2004)
J Biol Chem
, vol.279
, pp. 5661-5666
-
-
Ahn, E.Y.1
Lim, S.T.2
Cook, W.J.3
McDonald, J.M.4
-
27
-
-
0037470166
-
Calcium/calmodulin-dependent protein kinase II regulation of c-FLIP expression and phosphorylation in modulation of Fas-mediated signaling in malignant glioma cells
-
Yang BF, Xiao C, Roa WH, Krammer PH, Hao C. Calcium/calmodulin-dependent protein kinase II regulation of c-FLIP expression and phosphorylation in modulation of Fas-mediated signaling in malignant glioma cells. J Biol Chem 2003;278:7043-50.
-
(2003)
J Biol Chem
, vol.278
, pp. 7043-7050
-
-
Yang, B.F.1
Xiao, C.2
Roa, W.H.3
Krammer, P.H.4
Hao, C.5
-
28
-
-
18344384228
-
Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway
-
He Q, Lee DI, Rong R, et al. Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway. Oncogene 2002;21:2623-33.
-
(2002)
Oncogene
, vol.21
, pp. 2623-2633
-
-
He, Q.1
Lee, D.I.2
Rong, R.3
-
29
-
-
0030726447
-
Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein
-
Sheikh MS, Carrier F, Papathanasiou MA, et al. Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein. J Biol Chem 1997;272:26720-6.
-
(1997)
J Biol Chem
, vol.272
, pp. 26720-26726
-
-
Sheikh, M.S.1
Carrier, F.2
Papathanasiou, M.A.3
-
30
-
-
0033522904
-
Cloning and characterization of a human genotoxic and endoplasmic reticulum stress-inducible cDNA that encodes translation initiation factor 1[eIF1(A121/SUI1)]
-
Sheikh MS, Fernandez-Salas E, Yu M, et al. Cloning and characterization of a human genotoxic and endoplasmic reticulum stress-inducible cDNA that encodes translation initiation factor 1[eIF1(A121/SUI1)]. J Biol Chem 1999;274:16487-93.
-
(1999)
J Biol Chem
, vol.274
, pp. 16487-16493
-
-
Sheikh, M.S.1
Fernandez-Salas, E.2
Yu, M.3
-
32
-
-
0026849821
-
Definition of a consensus binding site for p53
-
el-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B. Definition of a consensus binding site for p53. Nat Genet 1992;1:45-9.
-
(1992)
Nat Genet
, vol.1
, pp. 45-49
-
-
Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
33
-
-
0034640281
-
Noxa, a BH3-only member of the bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, et al. Noxa, a BH3-only member of the bcl-2 family and candidate mediator of p53-induced apoptosis. Science 2000;288:1053-8.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
-
34
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu GS, Burns TF, McDonald ER III, et al. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 1997;17:141-3.
-
(1997)
Nat Genet
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald III, E.R.3
-
35
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995;80:293-9.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
36
-
-
0035843156
-
Negative regulation of bcl-2 expression by p53 in hematopoietic cells
-
Wu Y, Mehew JW, Heckman CA, et al. Negative regulation of bcl-2 expression by p53 in hematopoietic cells. Oncogene 2001;20:240-51.
-
(2001)
Oncogene
, vol.20
, pp. 240-251
-
-
Wu, Y.1
Mehew, J.W.2
Heckman, C.A.3
-
37
-
-
0036479115
-
Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
-
Huffman WH, Biade S, Zilfou JT, et al. Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. J Biol Chem 2002;277:3247-57.
-
(2002)
J Biol Chem
, vol.277
, pp. 3247-3257
-
-
Huffman, W.H.1
Biade, S.2
Zilfou, J.T.3
-
38
-
-
0035953394
-
DNA microarrays identification of primary and secondary target genes regulated by p53
-
Kannan K, Amariglio N, Rechavi G, et al. DNA microarrays identification of primary and secondary target genes regulated by p53. Oncogene 2001;20:2225-34.
-
(2001)
Oncogene
, vol.20
, pp. 2225-2234
-
-
Kannan, K.1
Amariglio, N.2
Rechavi, G.3
-
39
-
-
0035920197
-
Transcriptional repression by p53 through direct binding to a novel DNA element
-
Johnson RA, Ince TA, Scotto KW. Transcriptional repression by p53 through direct binding to a novel DNA element. J Biol Chem 2001;276:27716-20.
-
(2001)
J Biol Chem
, vol.276
, pp. 27716-27720
-
-
Johnson, R.A.1
Ince, T.A.2
Scotto, K.W.3
-
40
-
-
0037135581
-
A novel p53 transcriptional represser element (p53TRE) and the asymmetrical contribution of two p53 binding sites modulate the response of the placental transforming growth factor-β promoter to p53
-
Wong J, Li PX, Klamut HJ. A novel p53 transcriptional represser element (p53TRE) and the asymmetrical contribution of two p53 binding sites modulate the response of the placental transforming growth factor-β promoter to p53. J Biol Chem 2002;277:26699-707.
-
(2002)
J Biol Chem
, vol.277
, pp. 26699-26707
-
-
Wong, J.1
Li, P.X.2
Klamut, H.J.3
-
41
-
-
0027469281
-
Regulation of the human hsp70 promoter by p53
-
Agoff SN, Hou J, Linzer DI, Wu B. Regulation of the human hsp70 promoter by p53. Science 1993;259:84-7.
-
(1993)
Science
, vol.259
, pp. 84-87
-
-
Agoff, S.N.1
Hou, J.2
Linzer, D.I.3
Wu, B.4
-
43
-
-
13844280115
-
P53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription
-
Innocente SA, Lee JM. p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription. FEBS Lett 2005;579:1001-7.
-
(2005)
FEBS Lett
, vol.579
, pp. 1001-1007
-
-
Innocente, S.A.1
Lee, J.M.2
-
45
-
-
20144375842
-
Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin
-
Otto EA, Loeys B, Khanna H, et al. Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin. Nat Genet 2005;37:282-8.
-
(2005)
Nat Genet
, vol.37
, pp. 282-288
-
-
Otto, E.A.1
Loeys, B.2
Khanna, H.3
|