-
1
-
-
0028143317
-
The role of calcium, pH, and cell proliferation in the programmed (apoptotic) death of androgen-independent prostatic cancer cells induced by thapsigargin
-
Furuya Y, Lundmo P, Short AD, Gill DL, Isaacs JT. The role of calcium, pH, and cell proliferation in the programmed (apoptotic) death of androgen-independent prostatic cancer cells induced by thapsigargin. Cancer Res 1994;54:6167-75.
-
(1994)
Cancer Res
, vol.54
, pp. 6167-6175
-
-
Furuya, Y.1
Lundmo, P.2
Short, A.D.3
Gill, D.L.4
Isaacs, J.T.5
-
2
-
-
0032463011
-
The role of calcium in apoptosis
-
Krebs J. The role of calcium in apoptosis. BioMetals 1998;11:375-82.
-
(1998)
BioMetals
, vol.11
, pp. 375-382
-
-
Krebs, J.1
-
3
-
-
0037035807
-
Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis
-
Nutt LK, Chandra J, Pataer A, et al. Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis. J Biol Chem 2002;277:20301-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 20301-20308
-
-
Nutt, L.K.1
Chandra, J.2
Pataer, A.3
-
4
-
-
0037199911
-
Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression
-
Kim BC, Kim HT, Mamura M, Ambudkar IS, Choi KS, Kim SJ. Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression. J Biol Chem 2002:277: 31381-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 31381-31389
-
-
Kim, B.C.1
Kim, H.T.2
Mamura, M.3
Ambudkar, I.S.4
Choi, K.S.5
Kim, S.J.6
-
5
-
-
85047699156
-
A supramicromolar elevation of intracellular free calcium ([Ca(2+)](i)) is consistently required to induce the execution phase of apoptosis
-
Tombal B, Denmeade SR, Gillis JM, Isaacs JT. A supramicromolar elevation of intracellular free calcium ([Ca(2+)](i)) is consistently required to induce the execution phase of apoptosis. Cell Death Differ 2002;9:561-73.
-
(2002)
Cell Death Differ
, vol.9
, pp. 561-573
-
-
Tombal, B.1
Denmeade, S.R.2
Gillis, J.M.3
Isaacs, J.T.4
-
6
-
-
0025737973
-
Inhibition of the sarcoplasmic reticulum Ca2+ transport ATPase by thapsigargin at subnanomolar concentrations
-
Sagara Y, Inesi G. Inhibition of the sarcoplasmic reticulum Ca2+ transport ATPase by thapsigargin at subnanomolar concentrations. J Biol Chem 1991;266:13503-6.
-
(1991)
J Biol Chem
, vol.266
, pp. 13503-13506
-
-
Sagara, Y.1
Inesi, G.2
-
7
-
-
0029899181
-
Molecular thanatopsis: A discourse on the BCL2 family and cell death
-
Yang E, Korsmeyer SJ. Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 1996;88:368-401.
-
(1996)
Blood
, vol.88
, pp. 368-401
-
-
Yang, E.1
Korsmeyer, S.J.2
-
8
-
-
0029845983
-
Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria
-
Murphy AN, Bredesen E, Cortopassi G, Wang E, Fiskum G. Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proc Natl Acad Sci USA 1996;93:9893-8.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9893-9898
-
-
Murphy, A.N.1
Bredesen, E.2
Cortopassi, G.3
Wang, E.4
Fiskum, G.5
-
9
-
-
0032539673
-
Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux
-
Shimizu S, Eguchi Y, Kamiike W, et al. Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux. Proc Natl Acad Sci USA 1998;95:1455-9.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1455-1459
-
-
Shimizu, S.1
Eguchi, Y.2
Kamiike, W.3
-
10
-
-
0034705141
-
Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum
-
Foyouzi-Youssefi R, Arnaudeau S, Broner C, et al. Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum. Proc Natl Acad Sci USA 2000;97:5723-8.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5723-5728
-
-
Foyouzi-Youssefi, R.1
Arnaudeau, S.2
Broner, C.3
-
11
-
-
0037088658
-
Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores
-
Nutt LK, Pataer A, Pahler J, et al. Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores. J Biol Chem 2002;277, 9219-25.
-
(2002)
J Biol Chem
, vol.277
, pp. 9219-9225
-
-
Nutt, L.K.1
Pataer, A.2
Pahler, J.3
-
12
-
-
0030780106
-
Movement of Bax from the cytosol to mitochondria during apoptosis
-
Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG, Youle RJ. Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol 1997;139:1281-1292.
-
(1997)
J Cell Biol
, vol.139
, pp. 1281-1292
-
-
Wolter, K.G.1
Hsu, Y.T.2
Smith, C.L.3
Nechushtan, A.4
Xi, X.G.5
Youle, R.J.6
-
13
-
-
0030963602
-
Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis
-
Hsu YT, Wolter KG, Youle RJ. Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. Proc Natl Acad Sci USA 1997;94:3668-72.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3668-3672
-
-
Hsu, Y.T.1
Wolter, K.G.2
Youle, R.J.3
-
14
-
-
0033522391
-
Conformation of the Bax C-terminus regulates subcellular location and cell death
-
Nechushtan A, Smith CL, Hsu YT and Youle RJ. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J 1999;18:2330-41.
-
(1999)
EMBO J
, vol.18
, pp. 2330-2341
-
-
Nechushtan, A.1
Smith, C.L.2
Hsu, Y.T.3
Youle, R.J.4
-
15
-
-
0036312001
-
Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization
-
Boya P, Cohen I, Zamzami N, Vieira HLA, Kroemer G. Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization. Cell Death Differ 2002;9:465-7.
-
(2002)
Cell Death Differ
, vol.9
, pp. 465-467
-
-
Boya, P.1
Cohen, I.2
Zamzami, N.3
Vieira, H.L.A.4
Kroemer, G.5
-
16
-
-
0033519705
-
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
-
Shimizu S, Narita M, Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 1999;399:483-87.
-
(1999)
Nature
, vol.399
, pp. 483-487
-
-
Shimizu, S.1
Narita, M.2
Tsujimoto, Y.3
-
17
-
-
0034616945
-
-
Du C, Fang M, Li Y, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000;102:33-42.
-
Du C, Fang M, Li Y, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000;102:33-42.
-
-
-
-
18
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen AM, Ekert PG, Pakusch M, et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 2000;102:43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
-
19
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
Chai J, Du C, Wu JW, Kyin S, Wang X, Shi Y. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 2000;406:855-62.
-
(2000)
Nature
, vol.406
, pp. 855-862
-
-
Chai, J.1
Du, C.2
Wu, J.W.3
Kyin, S.4
Wang, X.5
Shi, Y.6
-
20
-
-
4344691959
-
Caspases, IAPs and Smac/DIABLO: Mechanisms from structural biology
-
Shiozaki EN, Shi Y. Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology. Trends Biochem Sci 2004;29:486-94.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 486-494
-
-
Shiozaki, E.N.1
Shi, Y.2
-
21
-
-
0034700491
-
Structural basis of IAP recognition by Smac/DIABLO
-
Wu G, Chai J, Suber TL, Wu JW, Du C, Wang X, Shi Y. Structural basis of IAP recognition by Smac/DIABLO. Nature 2000;408:1008-12.
-
(2000)
Nature
, vol.408
, pp. 1008-1012
-
-
Wu, G.1
Chai, J.2
Suber, T.L.3
Wu, J.W.4
Du, C.5
Wang, X.6
Shi, Y.7
-
22
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
-
Liu Z, Sun C, Olejniczak ET, et al. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature 2000;408:1004-8.
-
(2000)
Nature
, vol.408
, pp. 1004-1008
-
-
Liu, Z.1
Sun, C.2
Olejniczak, E.T.3
-
23
-
-
0036088471
-
IAP proteins: Blocking the road to death's door
-
Salvesen GS, Duckett CS. IAP proteins: blocking the road to death's door. Nat Rev Mol Cell Biol 2002;3:401-10.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 401-410
-
-
Salvesen, G.S.1
Duckett, C.S.2
-
24
-
-
0037291737
-
Mechanism of XIAP-mediated inhibition of caspase-9
-
Shiozaki EN, Chai J, Rigotti DJ, et al. Mechanism of XIAP-mediated inhibition of caspase-9. Mol Cell 2003;11:519-27.
-
(2003)
Mol Cell
, vol.11
, pp. 519-527
-
-
Shiozaki, E.N.1
Chai, J.2
Rigotti, D.J.3
-
25
-
-
0035831021
-
Structural basis of caspase-7 inhibition by XIAP
-
Chai J, Shiozaki E, Srinivasula SM, et al. Structural basis of caspase-7 inhibition by XIAP. Cell 2001;104:769-80.
-
(2001)
Cell
, vol.104
, pp. 769-780
-
-
Chai, J.1
Shiozaki, E.2
Srinivasula, S.M.3
-
26
-
-
37049019494
-
Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP
-
Sun H, Nikolovska-Coleska Z, Lu J, et al. Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP. J Am Chem Soc 2007;129:15279-94.
-
(2007)
J Am Chem Soc
, vol.129
, pp. 15279-15294
-
-
Sun, H.1
Nikolovska-Coleska, Z.2
Lu, J.3
-
27
-
-
10044265235
-
SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells
-
Kohli M, Yu J, Seaman C, et al. SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells. Proc Natl Acad Sci U S A 2004;101:16897-902.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 16897-16902
-
-
Kohli, M.1
Yu, J.2
Seaman, C.3
-
28
-
-
0037026582
-
Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells
-
He Q, Luo X, Huang Y and Sheikh MS. Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells. Oncogene 2002;21:6032-40.
-
(2002)
Oncogene
, vol.21
, pp. 6032-6040
-
-
He, Q.1
Luo, X.2
Huang, Y.3
Sheikh, M.S.4
-
29
-
-
18344384228
-
Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway
-
He Q, Lee DI, Rong R, et al. Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway. Oncogene 2002;21:2623-33.
-
(2002)
Oncogene
, vol.21
, pp. 2623-2633
-
-
He, Q.1
Lee, D.I.2
Rong, R.3
-
30
-
-
3042679658
-
Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells
-
Hasenjäger A, Gillissen B, Müller A, et al. Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells. Oncogene 2004;23:4523-35.
-
(2004)
Oncogene
, vol.23
, pp. 4523-4535
-
-
Hasenjäger, A.1
Gillissen, B.2
Müller, A.3
-
31
-
-
0035884187
-
Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells
-
Huang Y, He Q, Rong R, Hillman MJ, Sheikh MS. Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells. Cancer Res 2001;61:6918-24.
-
(2001)
Cancer Res
, vol.61
, pp. 6918-6924
-
-
Huang, Y.1
He, Q.2
Rong, R.3
Hillman, M.J.4
Sheikh, M.S.5
|