메뉴 건너뛰기




Volumn 25, Issue 4, 2010, Pages 819-829

Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: Role of the calcium-calcineurin-NFAT pathway

Author keywords

AP 1; CREB; MC3T3 E1; Prostaglandin; Protein kinase A

Indexed keywords

CALCINEURIN; CALCINEURIN INHIBITOR; CALCIUM; CRE RECOMBINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; FORSKOLIN; PARATHYROID HORMONE; PROTEIN C FOS; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT;

EID: 77953394873     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.091019     Document Type: Article
Times cited : (24)

References (58)
  • 1
    • 84882471619 scopus 로고    scopus 로고
    • Prostaglandins and bone metabolism
    • Bilezikian JPRL, Martin TJ, eds. 3rd ed. San Dirgo: Elsevier/Academic Press
    • Pilbeam C, Choudhary S, Blackwell K, Raisz LG. Prostaglandins and bone metabolism. In: Bilezikian JPRL, Martin TJ, eds. Principles of Bone Biology, 3rd ed. San Dirgo: Elsevier/Academic Press; 2008:1235-1271.
    • (2008) Principles of Bone Biology , pp. 1235-1271
    • Pilbeam, C.1    Choudhary, S.2    Blackwell, K.3    Raisz, L.G.4
  • 2
    • 0030479496 scopus 로고    scopus 로고
    • Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2
    • Smith WL, Garavito RM, DeWitt DL. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem. 1996;271:33157-33160.
    • (1996) J Biol Chem , vol.271 , pp. 33157-33160
    • Smith, W.L.1    Garavito, R.M.2    DeWitt, D.L.3
  • 3
    • 0030422719 scopus 로고    scopus 로고
    • Function and regulation of prostaglandin synthase-2
    • Herschman HR, Reddy ST, Xie W. Function and regulation of prostaglandin synthase-2. Adv Exp Med Biol. 1997;407:61-66.
    • (1997) Adv Exp Med Biol , vol.407 , pp. 61-66
    • Herschman, H.R.1    Reddy, S.T.2    Xie, W.3
  • 4
    • 0034284550 scopus 로고    scopus 로고
    • Therapeutic approaches to bone diseases
    • Rodan GA, Martin TJ. Therapeutic approaches to bone diseases. Science. 2000;289:1508-1514.
    • (2000) Science , vol.289 , pp. 1508-1514
    • Rodan, G.A.1    Martin, T.J.2
  • 5
    • 36549086789 scopus 로고    scopus 로고
    • Progress, paradox, and potential: Parathyroid hormone research over five decades
    • Potts JT, Gardella TJ. Progress, paradox, and potential: parathyroid hormone research over five decades. Ann NY Acad Sci. 2007;1117:196-208.
    • (2007) Ann NY Acad Sci , vol.1117 , pp. 196-208
    • Potts, J.T.1    Gardella, T.J.2
  • 6
    • 33845983304 scopus 로고    scopus 로고
    • The use of parathyroid hormone in the treatment of osteoporosis
    • DOI 10.1007/s11154-006-9007-z, Special Issue on Osteoporosis
    • Girotra M, Rubin MR, Bilezikian JP. The use of parathyroid hormone in the treatment of osteoporosis. Rev Endocr Metab Disord. 2006;7:113-121. (Pubitemid 46049523)
    • (2006) Reviews in Endocrine and Metabolic Disorders , vol.7 , Issue.1-2 , pp. 113-121
    • Girotra, M.1    Rubin, M.R.2    Bilezikian, J.P.3
  • 8
    • 0030459716 scopus 로고    scopus 로고
    • Parathyroid hormone induces prostaglandin G/H synthase-2 expression by a cyclic adenosine 3',5'-monophosphate-mediated pathway in the murine osteoblastic cell line MC3T3-E1
    • DOI 10.1210/en.137.12.5435
    • Tetradis S, Pilbeam CC, Liu Y, Kream BE. Parathyroid hormone induces prostaglandin G/H synthase-2 expression by a cyclic adenosine 3′,5′-monophosphate-mediated pathway in the murine osteoblastic cell line MC3T3-E1. Endocrinology. 1996;137:5435-5440. (Pubitemid 26423107)
    • (1996) Endocrinology , vol.137 , Issue.12 , pp. 5435-5440
    • Tetradis, S.1    Pilbeam, C.C.2    Liu, Y.3    Kream, B.E.4
  • 9
    • 0030756167 scopus 로고    scopus 로고
    • Parathyroid hormone increases prostaglandin G/H synthase-2 transcription by a cyclic adenosine 3',5'-monophosphate-mediated pathway in murine osteoblastic MC3T3-E1 cells
    • DOI 10.1210/en.138.9.3594
    • Tetradis S, Pilbeam CC, Liu Y, Herschman HR, Kream BE. Parathyroid hormone increases prostaglandin G/H synthase-2 transcription by a cyclic adenosine 3′,5′-monophosphate-mediated pathway in murine osteoblastic MC3T3-E1 cells. Endocrinology. 1997;138:3594-3600. (Pubitemid 27351904)
    • (1997) Endocrinology , vol.138 , Issue.9 , pp. 3594-3600
    • Tetradis, S.1    Pilbeam, C.C.2    Liu, Y.3    Herschman, H.R.4    Kream, B.E.5
  • 12
    • 0029095021 scopus 로고
    • Regulation of granulocyte-macrophage colony-stimulating factor and E-selectin expression in endothelial cells by cyclosporin A and the T-cell transcription factor NFAT
    • Cockerill GW, Bert AG, Ryan GR, Gamble JR, Vadas MA, Cockerill PN. Regulation of granulocyte-macrophage colony-stimulating factor and E-selectin expression in endothelial cells by cyclosporin A and the T-cell transcription factor NFAT. Blood. 1995;86:2689-2698.
    • (1995) Blood , vol.86 , pp. 2689-2698
    • Cockerill, G.W.1    Bert, A.G.2    Ryan, G.R.3    Gamble, J.R.4    Vadas, M.A.5    Cockerill, P.N.6
  • 13
    • 0035809312 scopus 로고    scopus 로고
    • Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: Roles of the nuclear factor of activated T cells and cyclooxygenase 2
    • DOI 10.1084/jem.193.5.607
    • Hernandez GL, Volpert OV, Iniguez MA, Lorenzo E, Martinez-Martinez S, Grau R, Fresno M, Redondo JM. Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2. J Exp Med. 2001;193:607-620. (Pubitemid 32539557)
    • (2001) Journal of Experimental Medicine , vol.193 , Issue.5 , pp. 607-620
    • Hernandez, G.L.1    Volpert, O.V.2    Iniguez, M.A.3    Lorenzo, E.4    Martinez-Martinez, S.5    Grau, R.6    Fresno, M.7    Redondo, J.M.8
  • 15
    • 0141483523 scopus 로고    scopus 로고
    • Transcriptional regulation by calcium, calcineurin, and NFAT
    • DOI 10.1101/gad.1102703
    • Hogan PG, Chen L, Nardone J, Rao A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev. 2003;17:2205-2232. (Pubitemid 37128637)
    • (2003) Genes and Development , vol.17 , Issue.18 , pp. 2205-2232
    • Hogan, P.G.1    Chen, L.2    Nardone, J.3    Rao, A.4
  • 16
    • 0035971436 scopus 로고    scopus 로고
    • Partners in transcription: NFAT and AP-1
    • Macian F, Lopez-Rodriguez C, Rao A. Partners in transcription: NFAT and AP-1. Oncogene. 2001;20:2476-2489.
    • (2001) Oncogene , vol.20 , pp. 2476-2489
    • Macian, F.1    Lopez-Rodriguez, C.2    Rao, A.3
  • 17
    • 1842690120 scopus 로고    scopus 로고
    • The Calcineurin/Nuclear Factor of Activated T Cells Signaling Pathway Regulates Osteoclastogenesis in RAW264.7 Cells
    • DOI 10.1074/jbc.M213067200
    • Hirotani H, Tuohy NA, Woo JT, Stern PH, Clipstone NA. The calcineurin/nuclear factor of activated T cells signaling pathway regulates osteoclastogenesis in RAW264.7 cells. J Biol Chem. 2004;279:13984-13992. (Pubitemid 38468932)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.14 , pp. 13984-13992
    • Hirotani, H.1    Tuohy, N.A.2    Woo, J.-T.3    Stern, P.H.4    Clipstone, N.A.5
  • 21
    • 0034604683 scopus 로고    scopus 로고
    • An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes
    • DOI 10.1074/jbc.M001381200
    • Iniguez MA, Martinez-Martinez S, Punzon C, Redondo JM, Fresno M. An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes. J Biol Chem. 2000;275:23627-23635. (Pubitemid 30624647)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.31 , pp. 23627-23635
    • Iniguez, M.A.1    Martinez-Martinez, S.2    Punzon, C.3    Redondo, M.J.4    Fresno, M.5
  • 22
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells encodes a novel prostaglandin synthase/cyclooxygenase homologue
    • Kujubu DA, Fletcher BS, Varnum BC, Lim RW, Herschman HR. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem. 1991;266:12866-12872.
    • (1991) J Biol Chem , vol.266 , pp. 12866-12872
    • Kujubu, D.A.1    Fletcher, B.S.2    Varnum, B.C.3    Lim, R.W.4    Herschman, H.R.5
  • 23
    • 0026702494 scopus 로고
    • Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase
    • Fletcher BS, Kujubu DA, Perrin DM, Herschman HR. Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase. J Biol Chem. 1992;267:4338-4344.
    • (1992) J Biol Chem , vol.267 , pp. 4338-4344
    • Fletcher, B.S.1    Kujubu, D.A.2    Perrin, D.M.3    Herschman, H.R.4
  • 24
    • 0028229156 scopus 로고
    • Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene
    • Bazan NG, Fletcher BS, Herschman HR, Mukherjee PK. Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene. Proc Natl Acad Sci U S A. 1994;91:5252-5256.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5252-5256
    • Bazan, N.G.1    Fletcher, B.S.2    Herschman, H.R.3    Mukherjee, P.K.4
  • 25
    • 0032983542 scopus 로고    scopus 로고
    • Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential
    • DOI 10.1359/jbmr.1999.14.6.893
    • Wang D, Christensen K, Chawla K, Xiao G, Krebsbach PH, Franceschi RT. Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res. 1999;14:893-903. (Pubitemid 29262883)
    • (1999) Journal of Bone and Mineral Research , vol.14 , Issue.6 , pp. 893-903
    • Wang, D.1    Christensen, K.2    Chawla, K.3    Xiao, G.4    Krebsbach, P.H.5    Franceschi, R.T.6
  • 26
    • 0034125333 scopus 로고    scopus 로고
    • Identification of multiple cis-acting elements mediating the induction of prostaglandin G/H synthase-2 by phorbol ester in murine osteoblastic cells
    • Okada Y, Voznesensky O, Herschman H, Harrison J, Pilbeam C. Identification of multiple cis-acting elements mediating the induction of prostaglandin G/H synthase-2 by phorbol ester in murine osteoblastic cells. J Cell Biochem. 2000;78:197-209.
    • (2000) J Cell Biochem , vol.78 , pp. 197-209
    • Okada, Y.1    Voznesensky, O.2    Herschman, H.3    Harrison, J.4    Pilbeam, C.5
  • 27
    • 0029950418 scopus 로고    scopus 로고
    • Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum
    • DOI 10.1074/jbc.271.49.31742
    • Xie W, Herschman HR. Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum. J Biol Chem. 1996;271:31742-31748. (Pubitemid 26408642)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.49 , pp. 31742-31748
    • Xie, W.1    Herschman, H.R.2
  • 28
    • 0027491776 scopus 로고
    • The T-cell transcription factor NFAT(p) is a substrate for calcineurin and interacts with Fos and Jun
    • DOI 10.1038/365352a0
    • Jain J, McCaffrey PG, Miner Z, Kerppola TK, Lambert JN, Verdine GL, Curran T, Rao A. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature. 1993;365:352-355. (Pubitemid 23288978)
    • (1993) Nature , vol.365 , Issue.6444 , pp. 352-355
    • Jain, J.1    McCaffrey, P.G.2    Miner, Z.3    Kerppola, T.K.4    Lambert, J.N.5    Verdine, G.L.6    Curran, T.7    Rao, A.8
  • 29
    • 0028857929 scopus 로고
    • Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation
    • Rooney JW, Sun YL, Glimcher LH, Hoey T. Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation. Mol Cell Biol. 1995;15:6299-6310.
    • (1995) Mol Cell Biol , vol.15 , pp. 6299-6310
    • Rooney, J.W.1    Sun, Y.L.2    Glimcher, L.H.3    Hoey, T.4
  • 32
    • 0026568306 scopus 로고
    • Structure-function relationship of parathyroid hormone: Activation of phospholipase-C, protein kinase-A and -C in osteosarcoma cells
    • Fujimori A, Cheng SL, Avioli LV, Civitelli R. Structure-function relationship of parathyroid hormone: activation of phospholipase-C, protein kinase-A and -C in osteosarcoma cells. Endocrinology. 1992;130:29-36.
    • (1992) Endocrinology , vol.130 , pp. 29-36
    • Fujimori, A.1    Cheng, S.L.2    Avioli, L.V.3    Civitelli, R.4
  • 33
    • 0037045407 scopus 로고    scopus 로고
    • Parathyroid hormone-dependent signaling pathways regulating genes in bone cells
    • DOI 10.1016/S0378-1119(01)00798-3, PII S0378111901007983
    • Swarthout JT, D'Alonzo RC, Selvamurugan N, Partridge NC. Parathyroid hormone-dependent signaling pathways regulating genes in bone cells. Gene. 2002;282:1-17. (Pubitemid 34117557)
    • (2002) Gene , vol.282 , Issue.1-2 , pp. 1-17
    • Swarthout, J.T.1    D'Alonzo, R.C.2    Selvamurugan, N.3    Partridge, N.C.4
  • 37
    • 0023155966 scopus 로고
    • K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases
    • DOI 10.1016/0006-291X(87)90293-2
    • Kase H, Iwahashi K, Nakanishi S, Matsuda Y, Yamada K, Takahashi M, Murakata C, Sato A, Kaneko M. K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem Biophys Res Commun. 1987;142:436-440. (Pubitemid 17003365)
    • (1987) Biochemical and Biophysical Research Communications , vol.142 , Issue.2 , pp. 436-440
    • Kase, H.1    Iwahashi, K.2    Nakanishi, S.3
  • 38
    • 0037151052 scopus 로고    scopus 로고
    • New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP
    • DOI 10.1074/jbc.M110364200
    • Fujita T, Meguro T, Fukuyama R, Nakamuta H, Koida M. New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP. J Biol Chem. 2002;277:22191-22200. (Pubitemid 34967184)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.25 , pp. 22191-22200
    • Fujita, T.1    Meguro, T.2    Fukuyama, R.3    Nakamuta, H.4    Koida, M.5
  • 40
    • 0037093955 scopus 로고    scopus 로고
    • Sustained NFAT signaling promotes a Th1-like pattern of gene expression in primary murine CD4+ T cells
    • Porter CM, Clipstone NA. Sustained NFAT signaling promotes a Th1-like pattern of gene expression in primary murine CD4+ T cells. J Immunol. 2002;168:4936-4945.
    • (2002) J Immunol , vol.168 , pp. 4936-4945
    • Porter, C.M.1    Clipstone, N.A.2
  • 41
    • 0033517718 scopus 로고    scopus 로고
    • Transcriptional regulation of the cyclooxygenase-2 gene by diverse ligands in murine osteoblasts
    • Wadleigh DJ, Herschman HR. Transcriptional regulation of the cyclooxygenase-2 gene by diverse ligands in murine osteoblasts. Biochem Biophys Res Commun. 1999;264:865-870.
    • (1999) Biochem Biophys Res Commun , vol.264 , pp. 865-870
    • Wadleigh, D.J.1    Herschman, H.R.2
  • 42
    • 34247505895 scopus 로고    scopus 로고
    • Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation
    • DOI 10.1016/j.plipres.2007.01.001, PII S0163782707000021
    • Kang YJ, Mbonye UR, DeLong CJ, Wada M, Smith WL. Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation. Prog Lipid Res. 2007;46:108-125. (Pubitemid 46661865)
    • (2007) Progress in Lipid Research , vol.46 , Issue.2 , pp. 108-125
    • Kang, Y.-J.1    Mbonye, U.R.2    Delong, C.J.3    Wada, M.4    Smith, W.L.5
  • 43
    • 0033590648 scopus 로고    scopus 로고
    • Both AP-1 and Cbfa1-like factors are required for the induction of interstitial collagenase by parathyroid hormone
    • DOI 10.1038/sj.onc.1202333
    • Porte D, Tuckermann J, Becker M, Baumann B, Teurich S, Higgins T, Owen MJ, Schorpp-Kistner M, Angel P. Both AP-1 and Cbfa1-like factors are required for the induction of interstitial collagenase by parathyroid hormone. Oncogene. 1999;18:667-678. (Pubitemid 29080324)
    • (1999) Oncogene , vol.18 , Issue.3 , pp. 667-678
    • Porte, D.1    Tuckermann, J.2    Becker, M.3    Baumann, B.4    Teurich, S.5    Higgins, T.6    Owen, M.J.7    Schorpp-Kistner, M.8    Angel, P.9
  • 44
    • 0032562581 scopus 로고    scopus 로고
    • Parathyroid hormone regulates the rat collagenase-3 promoter in osteoblastic cells through the cooperative interaction of the activator protein-1 site and the runt domain binding sequence
    • DOI 10.1074/jbc.273.17.10647
    • Selvamurugan N, Chou WY, Pearman AT, Pulumati MR, Partridge NC. Parathyroid hormone regulates the rat collagenase-3 promoter in osteoblastic cells through the cooperative interaction of the activator protein-1 site and the runt domain binding sequence. J Biol Chem. 1998;273:10647-10657. (Pubitemid 28227678)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.17 , pp. 10647-10657
    • Selvamurugan, N.1    Chou, W.-Y.2    Pearman, A.T.3    Pulumati, M.R.4    Partridge, N.C.5
  • 45
    • 0030665760 scopus 로고    scopus 로고
    • Proto-oncogene c-fos is transcriptionally regulated by parathyroid hormone (PTH) and PTH-related protein in a cyclic adenosine monophosphate- dependent manner in osteoblastic cells
    • McCauley LK, Koh AJ, Beecher CA, Rosol TJ. Proto-oncogene c-fos is transcriptionally regulated by parathyroid hormone (PTH) and PTH-related protein in a cyclic adenosine monophosphate-dependent manner in osteoblastic cells. Endocrinology. 1997;138:5427-5433.
    • (1997) Endocrinology , vol.138 , pp. 5427-5433
    • McCauley, L.K.1    Koh, A.J.2    Beecher, C.A.3    Rosol, T.J.4
  • 46
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • DOI 10.1146/annurev.immunol.15.1.707
    • Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol. 1997;15:707-747. (Pubitemid 27169297)
    • (1997) Annual Review of Immunology , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 47
    • 40449132279 scopus 로고    scopus 로고
    • Extracellular HIV-Tat induces cyclooxygenase-2 in glial cells through activation of nuclear factor of activated T cells
    • Blanco A, Alvarez S, Fresno M, Munoz-Fernandez MA. Extracellular HIV-Tat induces cyclooxygenase-2 in glial cells through activation of nuclear factor of activated T cells. J Immunol. 2008;180:530-540.
    • (2008) J Immunol , vol.180 , pp. 530-540
    • Blanco, A.1    Alvarez, S.2    Fresno, M.3    Munoz-Fernandez, M.A.4
  • 48
    • 57349155737 scopus 로고    scopus 로고
    • NFAT regulates induction of COX-2 and apoptosis of keratinocytes in response to ultraviolet radiation exposure
    • Flockhart RJ, Diffey BL, Farr PM, Lloyd J, Reynolds NJ. NFAT regulates induction of COX-2 and apoptosis of keratinocytes in response to ultraviolet radiation exposure. FASEB J. 2008.
    • (2008) FASEB J
    • Flockhart, R.J.1    Diffey, B.L.2    Farr, P.M.3    Lloyd, J.4    Reynolds, N.J.5
  • 51
    • 0029016332 scopus 로고
    • Cyclic AMP inhibits expression of the IL-2 gene through the nuclear factor of activated T cells (NF-AT) site, and transfection of NF-AT cDNAs abrogates the sensitivity of EL-4 cells to cyclic AMP
    • Tsuruta L, Lee HJ, Masuda ES, Koyano-Nakagawa N, Arai N, Arai K, Yokota T. Cyclic AMP inhibits expression of the IL-2 gene through the nuclear factor of activated T cells (NF-AT) site, and transfection of NF-AT cDNAs abrogates the sensitivity of EL-4 cells to cyclic AMP. J Immunol. 1995;154:5255-5264.
    • (1995) J Immunol , vol.154 , pp. 5255-5264
    • Tsuruta, L.1    Lee, H.J.2    Masuda, E.S.3    Koyano-Nakagawa, N.4    Arai, N.5    Arai, K.6    Yokota, T.7
  • 52
    • 0036310155 scopus 로고    scopus 로고
    • NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1
    • Lawrence MC, Bhatt HS, Easom RA. NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1. Diabetes. 2002;51:691-698.
    • (2002) Diabetes , vol.51 , pp. 691-698
    • Lawrence, M.C.1    Bhatt, H.S.2    Easom, R.A.3
  • 53
    • 0035089841 scopus 로고    scopus 로고
    • Targeted protein kinase A and PP-2B regulate insulin secretion through reversible phosphorylation
    • Lester LB, Faux MC, Nauert JB, Scott JD. Targeted protein kinase A and PP-2B regulate insulin secretion through reversible phosphorylation. Endocrinology. 2001;142:1218-1227.
    • (2001) Endocrinology , vol.142 , pp. 1218-1227
    • Lester, L.B.1    Faux, M.C.2    Nauert, J.B.3    Scott, J.D.4
  • 54
    • 33746381639 scopus 로고    scopus 로고
    • AKAP signaling complexes: Getting to the heart of the matter
    • DOI 10.1016/j.molmed.2006.05.008, PII S1471491406001158
    • McConnachie G, Langeberg LK, Scott JD. AKAP signaling complexes: getting to the heart of the matter. Trends Mol Med. 2006;12:317-323. (Pubitemid 44110003)
    • (2006) Trends in Molecular Medicine , vol.12 , Issue.7 , pp. 317-323
    • McConnachie, G.1    Langeberg, L.K.2    Scott, J.D.3
  • 55
    • 30544452653 scopus 로고    scopus 로고
    • The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling
    • DOI 10.1242/jcs.02675
    • Pare GC, Bauman AL, McHenry M, Michel JJ, Dodge-Kafka KL, Kapiloff MS. The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling. J Cell Sci. 2005;118:5637-5646. (Pubitemid 43079302)
    • (2005) Journal of Cell Science , vol.118 , Issue.23 , pp. 5637-5646
    • Pare, G.C.1    Bauman, A.L.2    McHenry, M.3    Carlisle Michel, J.J.4    Dodge-Kafka, K.L.5    Kapiloff, M.S.6
  • 56
    • 0036234543 scopus 로고    scopus 로고
    • NFAT signaling: Choreographing the social lives of cells
    • Crabtree GR, Olson EN. NFAT signaling: choreographing the social lives of cells. Cell. 2002;109 Suppl: S67-79.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Crabtree, G.R.1    Olson, E.N.2
  • 57
    • 33744992976 scopus 로고    scopus 로고
    • The mAKAP signaling complex: Integration of cAMP, calcium, and MAP kinase signaling pathways
    • Dodge-Kafka KL, Kapiloff MS. The mAKAP signaling complex: integration of cAMP, calcium, and MAP kinase signaling pathways. Eur J Cell Biol. 2006;85:593-602.
    • (2006) Eur J Cell Biol , vol.85 , pp. 593-602
    • Dodge-Kafka, K.L.1    Kapiloff, M.S.2
  • 58
    • 34248674384 scopus 로고    scopus 로고
    • Cyclosporin a elicits dose-dependent biphasic effects on osteoblast differentiation and bone formation
    • DOI 10.1016/j.bone.2007.02.017, PII S8756328207000944
    • Yeo H, Beck LH, McDonald JM, Zayzafoon M. Cyclosporin A elicits dose-dependent biphasic effects on osteoblast differentiation and bone formation. Bone. 2007;40:1502-1516. (Pubitemid 46766648)
    • (2007) Bone , vol.40 , Issue.6 , pp. 1502-1516
    • Yeo, H.1    Beck, L.H.2    McDonald, J.M.3    Zayzafoon, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.