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Volumn 297, Issue 1, 2002, Pages 46-51

Fluid flow induces COX-2 expression in MC3T3-E1 osteoblasts via a PKA signaling pathway

Author keywords

Bone; Cyclooxygenase; Mechanical loading; Prostaglandins; Signal transduction

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLOOXYGENASE 2; FORSKOLIN; LUCIFERASE; MESSENGER RNA; PROTEIN KINASE C;

EID: 0036385945     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02124-1     Document Type: Conference Paper
Times cited : (76)

References (33)
  • 1
    • 0033166193 scopus 로고    scopus 로고
    • The role of prostaglandins and nitric oxide in the response of bone to mechanical forces
    • T.J. Chambers, S. Fox, C.J. Jagger, J.M. Lean, J.W. Chow, The role of prostaglandins and nitric oxide in the response of bone to mechanical forces, Osteoarthritis Cartilage 7 (1999) 422-423.
    • (1999) Osteoarthritis Cartilage , vol.7 , pp. 422-423
    • Chambers, T.J.1    Fox, S.2    Jagger, C.J.3    Lean, J.M.4    Chow, J.W.5
  • 2
    • 0028015986 scopus 로고
    • Indomethacin has distinct early and late actions on bone formation induced by mechanical stimulation
    • J.W. Chow, T.J. Chambers, Indomethacin has distinct early and late actions on bone formation induced by mechanical stimulation, Am. J. Physiol. 267 (1994) E287-E292.
    • (1994) Am. J. Physiol. , vol.267
    • Chow, J.W.1    Chambers, T.J.2
  • 3
    • 0024359708 scopus 로고
    • Indomethacin modulation of load-related stimulation of new bone formation in vivo
    • M.J. Pead, L.E. Lanyon, Indomethacin modulation of load-related stimulation of new bone formation in vivo, Calcif. Tissue Int. 45 (1989) 34-40.
    • (1989) Calcif. Tissue Int. , vol.45 , pp. 34-40
    • Pead, M.J.1    Lanyon, L.E.2
  • 4
    • 0002036601 scopus 로고    scopus 로고
    • Prostaglandins and bone metabolism
    • J.P. Bilezikian, L.G. Raisz, G.A. Rodan (Eds.), Academic Press, New York
    • C.C. Pilbeam, J.R. Harrison, L.G. Raisz, Prostaglandins and bone metabolism, in: J.P. Bilezikian, L.G. Raisz, G.A. Rodan (Eds.), Principles of Bone Biology, Academic Press, New York, 2002, pp. 979-995.
    • (2002) Principles of Bone Biology , pp. 979-995
    • Pilbeam, C.C.1    Harrison, J.R.2    Raisz, L.G.3
  • 5
    • 0029998565 scopus 로고    scopus 로고
    • Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo
    • M.R. Forwood, Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo, J. Bone Miner. Res. 11 (1996) 1688-1693.
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 1688-1693
    • Forwood, M.R.1
  • 8
    • 0026048690 scopus 로고
    • Effect of flow on prostaglandin E2 and inositol trisphosphate levels in osteoblasts
    • K.M. Reich, J.A. Frangos, Effect of flow on prostaglandin E2 and inositol trisphosphate levels in osteoblasts, Am. J. Physiol. 261 (1991) C428-C432.
    • (1991) Am. J. Physiol. , vol.261
    • Reich, K.M.1    Frangos, J.A.2
  • 9
    • 0031035011 scopus 로고    scopus 로고
    • Pulsating fluid flow stimulates prostaglandin release and inducible prostaglandin G/H synthase mRNA expression in primary mouse bone cells
    • J. Klein-Nulend, E.H. Burger, C.M. Semeins, L.G. Raisz, C.C. Pilbeam, Pulsating fluid flow stimulates prostaglandin release and inducible prostaglandin G/H synthase mRNA expression in primary mouse bone cells, J. Bone Miner. Res. 12 (1997) 45-51.
    • (1997) J. Bone Miner. Res. , vol.12 , pp. 45-51
    • Klein-Nulend, J.1    Burger, E.H.2    Semeins, C.M.3    Raisz, L.G.4    Pilbeam, C.C.5
  • 10
    • 0036150538 scopus 로고    scopus 로고
    • Fluid flow induction of cyclo-oxygenase 2 gene expression in osteoblasts is dependent on an extracellular signal-regulated kinase signaling pathway
    • S. Wadhwa, S.L. Godwin, D.R. Peterson, M.A. Epstein, L.G. Raisz, C.C. Pilbeam, Fluid flow induction of cyclo-oxygenase 2 gene expression in osteoblasts is dependent on an extracellular signal-regulated kinase signaling pathway, J. Bone Miner. Res. 17 (2002) 266-274.
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 266-274
    • Wadhwa, S.1    Godwin, S.L.2    Peterson, D.R.3    Epstein, M.A.4    Raisz, L.G.5    Pilbeam, C.C.6
  • 12
    • 0031282974 scopus 로고    scopus 로고
    • PKC-epsilon is required for mechano-sensitive activation of ERK1/2 in endothelial cells
    • O. Traub, B.P. Monia, N.M. Dean, B.C. Berk, PKC-epsilon is required for mechano-sensitive activation of ERK1/2 in endothelial cells, J. Biol. Chem. 272 (1997) 31251-31257.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31251-31257
    • Traub, O.1    Monia, B.P.2    Dean, N.M.3    Berk, B.C.4
  • 13
    • 0027409508 scopus 로고
    • Protein kinase C mediates flow-induced prostaglandin E2 production in osteoblasts
    • K.M. Reich, J.A. Frangos, Protein kinase C mediates flow-induced prostaglandin E2 production in osteoblasts, Calcif. Tissue Int. 52 (1993) 62-66.
    • (1993) Calcif. Tissue Int. , vol.52 , pp. 62-66
    • Reich, K.M.1    Frangos, J.A.2
  • 14
    • 0032924033 scopus 로고    scopus 로고
    • Signal transduction pathways involved in fluid flow-induced PGE2 production by cultured osteocytes
    • N.E. Ajubi, J. Klein-Nulend, M.J. Alblas, E.H. Burger, P.J. Nijweide, Signal transduction pathways involved in fluid flow-induced PGE2 production by cultured osteocytes, Am. J. Physiol. 276 (1999) E171-E178.
    • (1999) Am. J. Physiol. , vol.276
    • Ajubi, N.E.1    Klein-Nulend, J.2    Alblas, M.J.3    Burger, E.H.4    Nijweide, P.J.5
  • 15
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
    • D.A. Kujubu, B.S. Fletcher, B.C. Varnum, R.W. Lim, H.R. Herschman, TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue, J. Biol. Chem. 266 (1991) 12866-12872.
    • (1991) J. Biol. Chem. , vol.266 , pp. 12866-12872
    • Kujubu, D.A.1    Fletcher, B.S.2    Varnum, B.C.3    Lim, R.W.4    Herschman, H.R.5
  • 16
    • 0028229156 scopus 로고
    • Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene
    • N.G. Bazan, B.S. Fletcher, H.R. Herschman, P.K. Mukherjee, Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene, Proc. Natl. Acad. Sci. USA 91 (1994) 5252-5256.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5252-5256
    • Bazan, N.G.1    Fletcher, B.S.2    Herschman, H.R.3    Mukherjee, P.K.4
  • 18
    • 0034125333 scopus 로고    scopus 로고
    • Identification of multiple cis-acting elements mediating the induction of prostaglandin G/H synthase-2 by phorbol ester in murine osteoblastic cells
    • Y. Okada, O. Voznesensky, H. Herschman, J. Harrison, C. Pilbeam, Identification of multiple cis-acting elements mediating the induction of prostaglandin G/H synthase-2 by phorbol ester in murine osteoblastic cells, J. Cell. Biochem. 78 (2000) 197-209.
    • (2000) J. Cell. Biochem. , vol.78 , pp. 197-209
    • Okada, Y.1    Voznesensky, O.2    Herschman, H.3    Harrison, J.4    Pilbeam, C.5
  • 19
    • 0030807892 scopus 로고    scopus 로고
    • Transforming growth factor-β1 regulation of prostaglandin G/H synthase-2 expression in osteoblastic MC3T3-E1 cells
    • C. Pilbeam, Y. Rao, O. Voznesensky, H. Kawaguchi, C. Alander, L. Raisz, H. Herschman:, Transforming growth factor-β1 regulation of prostaglandin G/H synthase-2 expression in osteoblastic MC3T3-E1 cells, Endocrinology 138 (1997) 4672-4682.
    • (1997) Endocrinology , vol.138 , pp. 4672-4682
    • Pilbeam, C.1    Rao, Y.2    Voznesensky, O.3    Kawaguchi, H.4    Alander, C.5    Raisz, L.6    Herschman, H.7
  • 21
    • 0031587746 scopus 로고    scopus 로고
    • Pseudosubstrate inhibition of cyclic AMP-dependent protein kinase in intact pancreatic islets: Effects on cyclic AMP-dependent and glucose-dependent insulin secretion
    • T.E. Harris, S.J. Persaud, P.M. Jones, Pseudosubstrate inhibition of cyclic AMP-dependent protein kinase in intact pancreatic islets: effects on cyclic AMP-dependent and glucose-dependent insulin secretion, Biochem. Biophys. Res. Commun. 232 (1997) 648-651.
    • (1997) Biochem. Biophys. Res. Commun. , vol.232 , pp. 648-651
    • Harris, T.E.1    Persaud, S.J.2    Jones, P.M.3
  • 22
    • 0025248571 scopus 로고
    • Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquino-linesulfonamide (H-89), of PC12D pheochromocytoma cells
    • T. Chijiwa, A. Mishima, M. Hagiwara, M. Sano, K. Hayashi, T. Inoue, K. Naito, T. Toshioka, H. Hidaka, Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquino-linesulfonamide (H-89), of PC12D pheochromocytoma cells, J. Biol. Chem. 265 (1990) 5267-5272.
    • (1990) J. Biol. Chem. , vol.265 , pp. 5267-5272
    • Chijiwa, T.1    Mishima, A.2    Hagiwara, M.3    Sano, M.4    Hayashi, K.5    Inoue, T.6    Naito, K.7    Toshioka, T.8    Hidaka, H.9
  • 24
    • 0026794439 scopus 로고
    • The structure and biological activities of the widely used protein kinase inhibitor, H7, differ depending on the commercial source
    • J. Quick, J.A. Ware, P.E. Driedger, The structure and biological activities of the widely used protein kinase inhibitor, H7, differ depending on the commercial source, Biochem. Biophys. Res. Commun. 187 (1992) 657-663.
    • (1992) Biochem. Biophys. Res. Commun. , vol.187 , pp. 657-663
    • Quick, J.1    Ware, J.A.2    Driedger, P.E.3
  • 25
    • 0025359865 scopus 로고
    • Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production
    • K.M. Reich, C.V. Gay, J.A. Frangos, Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production, J. Cell. Physiol. 143 (1990) 100-104.
    • (1990) J. Cell. Physiol. , vol.143 , pp. 100-104
    • Reich, K.M.1    Gay, C.V.2    Frangos, J.A.3
  • 27
    • 0027772672 scopus 로고
    • Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate
    • J. Wu, P. Dent, T. Jelinek, A. Wolfman, M.J. Weber, T.W. Sturgill, Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate, Science 262 (1993) 1065-1069.
    • (1993) Science , vol.262 , pp. 1065-1069
    • Wu, J.1    Dent, P.2    Jelinek, T.3    Wolfman, A.4    Weber, M.J.5    Sturgill, T.W.6
  • 28
    • 0030963439 scopus 로고    scopus 로고
    • cAMP activates MAP kinase and Elk-1 through a B-Raf-and Rap1-dependent pathway
    • M.R. Vossler, H. Yao, R.D. York, M.G. Pan, C.S. Rim, P.J. Stork, cAMP activates MAP kinase and Elk-1 through a B-Raf-and Rap1-dependent pathway, Cell 89 (1997) 73-82.
    • (1997) Cell , vol.89 , pp. 73-82
    • Vossler, M.R.1    Yao, H.2    York, R.D.3    Pan, M.G.4    Rim, C.S.5    Stork, P.J.6
  • 29
    • 0029118037 scopus 로고
    • Parathyroid hormone inhibits mitogen-activated protein kinase activation in osteosarcoma cells via a protein kinase A-dependent pathway
    • M.H. Verheijen, L.H. Defize, Parathyroid hormone inhibits mitogen-activated protein kinase activation in osteosarcoma cells via a protein kinase A-dependent pathway, Endocrinology 136 (1995) 3331-3337.
    • (1995) Endocrinology , vol.136 , pp. 3331-3337
    • Verheijen, M.H.1    Defize, L.H.2
  • 30
    • 0028824346 scopus 로고
    • Forskolin inhibits protein kinase C-induced mitogen activated protein kinase activity in MC3T3-E1 osteoblasts
    • S.R. Siddhanti, J.E. Hartle, 2nd, L.D. Quarles, Forskolin inhibits protein kinase C-induced mitogen activated protein kinase activity in MC3T3-E1 osteoblasts, Endocrinology 136 (1995) 4834-4841.
    • (1995) Endocrinology , vol.136 , pp. 4834-4841
    • Siddhanti, S.R.1    Hartle J.E. II2    Quarles, L.D.3
  • 31
    • 0031888597 scopus 로고    scopus 로고
    • Identification and activation of mitogen-activated protein (MAP) kinase in normal human osteoblastic and bone marrow stromal cells: Attenuation of MAP kinase activation by cAMP, parathyroid hormone and forskolin
    • L.R. Chaudhary, L.V. Avioli, Identification and activation of mitogen-activated protein (MAP) kinase in normal human osteoblastic and bone marrow stromal cells: attenuation of MAP kinase activation by cAMP, parathyroid hormone and forskolin, Mol. Cell. Biochem. 178 (1998) 59-68.
    • (1998) Mol. Cell. Biochem. , vol.178 , pp. 59-68
    • Chaudhary, L.R.1    Avioli, L.V.2
  • 32
    • 33644986723 scopus 로고    scopus 로고
    • MAP kinase signaling cascades and gene expression in osteoblasts
    • R.A. Hipskind, G. Bilbe, MAP kinase signaling cascades and gene expression in osteoblasts, Front Biosci. 3 (1998) D804-D816.
    • (1998) Front Biosci. , vol.3
    • Hipskind, R.A.1    Bilbe, G.2
  • 33
    • 0032914450 scopus 로고    scopus 로고
    • Increased osteoblastic c-fos expression by parathyroid hormone requires protein kinase A phosphorylation of the cyclic adenosine 3′,5′-monophosphate response element-binding protein at serine 133
    • D.R. Tyson, J.T. Swarthout, N.C. Partridge, Increased osteo-blastic c-fos expression by parathyroid hormone requires protein kinase A phosphorylation of the cyclic adenosine 3′,5′-monophosphate response element-binding protein at serine 133, Endocrinology 140 (1999) 1255-1261.
    • (1999) Endocrinology , vol.140 , pp. 1255-1261
    • Tyson, D.R.1    Swarthout, J.T.2    Partridge, N.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.