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Volumn 180, Issue 1, 2008, Pages 530-540

Extracellular HIV-tat induces cyclooxygenase-2 in glial cells through activation of nuclear factor of activated T cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEAR FACTOR; PROSTAGLANDIN E2; PROTEIN C JUN; PROTEIN TAM 67; STRESS ACTIVATED PROTEIN KINASE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; PTGS2 PROTEIN, HUMAN;

EID: 40449132279     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.1.530     Document Type: Article
Times cited : (21)

References (74)
  • 3
    • 0042869762 scopus 로고    scopus 로고
    • Marked improvement in survival following AIDS dementia complex in the era of highly active antiretroviral therapy
    • Dore, G. J., A. McDonald, Y. Li, J. M. Kaldor, and B. J. Brew. 2003. Marked improvement in survival following AIDS dementia complex in the era of highly active antiretroviral therapy. AIDS 17: 1539-1545.
    • (2003) AIDS , vol.17 , pp. 1539-1545
    • Dore, G.J.1    McDonald, A.2    Li, Y.3    Kaldor, J.M.4    Brew, B.J.5
  • 5
    • 27744522735 scopus 로고    scopus 로고
    • Cross talk between growth factors and viral and cellular factors alters neuronal signaling pathways: Implication for HIV-associated dementia
    • Peruzzi, F., V. Bergonzini, S. Aprea, K. Reiss, B. E. Sawaya, J. Rappaport, S. Amini, and K. Khalili. 2005. Cross talk between growth factors and viral and cellular factors alters neuronal signaling pathways: implication for HIV-associated dementia. Brain Res. Rev. 50: 114-125.
    • (2005) Brain Res. Rev , vol.50 , pp. 114-125
    • Peruzzi, F.1    Bergonzini, V.2    Aprea, S.3    Reiss, K.4    Sawaya, B.E.5    Rappaport, J.6    Amini, S.7    Khalili, K.8
  • 6
    • 0034991754 scopus 로고    scopus 로고
    • Immunopathogenesis of HIV-associated dementia
    • Wesselingh, S. L., and K. A. Thompson. 2001. Immunopathogenesis of HIV-associated dementia. Curr. Opin. Neurol. 14: 375-379.
    • (2001) Curr. Opin. Neurol , vol.14 , pp. 375-379
    • Wesselingh, S.L.1    Thompson, K.A.2
  • 7
    • 21344455519 scopus 로고    scopus 로고
    • Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus
    • Kramer-Hammerle, S., I. Rothenaigner, H. Wolff, J. E. Bell, and R. Brack-Werner. 2005. Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus. Virus Res. 111: 194-213.
    • (2005) Virus Res , vol.111 , pp. 194-213
    • Kramer-Hammerle, S.1    Rothenaigner, I.2    Wolff, H.3    Bell, J.E.4    Brack-Werner, R.5
  • 9
    • 0344157469 scopus 로고    scopus 로고
    • The role of tumour necrosis factor, interleukin 6, interferon-γ and inducible nitric oxide synthase in the development and pathology of the nervous system
    • Munoz-Fernandez, M. A., and M. Fresno. 1998. The role of tumour necrosis factor, interleukin 6, interferon-γ and inducible nitric oxide synthase in the development and pathology of the nervous system. Prog. Neurobiol. 56: 307-340.
    • (1998) Prog. Neurobiol , vol.56 , pp. 307-340
    • Munoz-Fernandez, M.A.1    Fresno, M.2
  • 10
    • 32944481298 scopus 로고    scopus 로고
    • The multiple functions of HIV-1 Tat: Proliferation versus apoptosis
    • Peruzzi, F. 2006. The multiple functions of HIV-1 Tat: proliferation versus apoptosis. Front. Biosci. 11: 708-717.
    • (2006) Front. Biosci , vol.11 , pp. 708-717
    • Peruzzi, F.1
  • 11
    • 0036800480 scopus 로고    scopus 로고
    • Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120
    • Haughey, N. J., and M. P. Mattson. 2002. Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120. J. Acquired Immune Defic. Syndr. 31 (Suppl. 2): S55-S61.
    • (2002) J. Acquired Immune Defic. Syndr , vol.31 , Issue.SUPPL. 2
    • Haughey, N.J.1    Mattson, M.P.2
  • 12
    • 0027458469 scopus 로고
    • Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation
    • Ensoli, B., L. Buonaguro, G. Barillari, V. Fiorelli, R. Gendelman, R. A. Morgan, P. Wingfield, and R. C. Gallo. 1993. Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J. Virol. 67: 277-287.
    • (1993) J. Virol , vol.67 , pp. 277-287
    • Ensoli, B.1    Buonaguro, L.2    Barillari, G.3    Fiorelli, V.4    Gendelman, R.5    Morgan, R.A.6    Wingfield, P.7    Gallo, R.C.8
  • 13
    • 0026784929 scopus 로고
    • Neurotoxicity of macrophages infected by HIV1
    • Tardieu, M., C. Hery, and S. Peudenier. 1992. Neurotoxicity of macrophages infected by HIV1. Cell Biol. Toxicol. 8: 117-121.
    • (1992) Cell Biol. Toxicol , vol.8 , pp. 117-121
    • Tardieu, M.1    Hery, C.2    Peudenier, S.3
  • 14
    • 0037631328 scopus 로고    scopus 로고
    • Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport
    • Chauhan, A., J. Turchan, C. Pocernich, A. Bruce-Keller, S. Roth, D. A. Butterfield, E. O. Major, and A. Nath. 2003. Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport. J. Biol. Chem. 278: 13512-13519.
    • (2003) J. Biol. Chem , vol.278 , pp. 13512-13519
    • Chauhan, A.1    Turchan, J.2    Pocernich, C.3    Bruce-Keller, A.4    Roth, S.5    Butterfield, D.A.6    Major, E.O.7    Nath, A.8
  • 16
    • 0030005329 scopus 로고    scopus 로고
    • Expression of HIV regulatory and structural mRNA in the central nervous system
    • Wiley, C. A., M. Baldwin, and C. L. Achim. 1996. Expression of HIV regulatory and structural mRNA in the central nervous system. AIDS 10: 843-847.
    • (1996) AIDS , vol.10 , pp. 843-847
    • Wiley, C.A.1    Baldwin, M.2    Achim, C.L.3
  • 17
    • 0011093360 scopus 로고
    • Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Escherichia coli: Demonstration of immunogenicity in vivo and expression in vitro
    • Aldovini, A., C. Debouck, M. B. Feinberg, M. Rosenberg, S. K. Arya, and F. Wong-Staal. 1986. Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Escherichia coli: demonstration of immunogenicity in vivo and expression in vitro. Proc. Natl. Acad. Sci. USA 83: 6672-6676.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 6672-6676
    • Aldovini, A.1    Debouck, C.2    Feinberg, M.B.3    Rosenberg, M.4    Arya, S.K.5    Wong-Staal, F.6
  • 18
    • 0031747096 scopus 로고    scopus 로고
    • Intraventricular injection of human immunodeficiency virus type 1 (HIV-1) tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement
    • Jones, M., K. Olafson, M. R. Del Bigio, J. Peeling, and A. Nath. 1998. Intraventricular injection of human immunodeficiency virus type 1 (HIV-1) tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement. J. Neuropathol. Exp. Neurol. 57: 563-570.
    • (1998) J. Neuropathol. Exp. Neurol , vol.57 , pp. 563-570
    • Jones, M.1    Olafson, K.2    Del Bigio, M.R.3    Peeling, J.4    Nath, A.5
  • 19
    • 0037406230 scopus 로고    scopus 로고
    • Neuropathologies in transgenic mice expressing human immunodeficiency virus type 1 Tat protein under the regulation of the astrocyte-specific glial fibrillary acidic protein promoter and doxycycline
    • Kim, B. O., Y. Liu, Y. Ruan, Z. C. Xu, L. Schantz, and J. J. He. 2003. Neuropathologies in transgenic mice expressing human immunodeficiency virus type 1 Tat protein under the regulation of the astrocyte-specific glial fibrillary acidic protein promoter and doxycycline. Am. J. Pathol. 162: 1693-1707.
    • (2003) Am. J. Pathol , vol.162 , pp. 1693-1707
    • Kim, B.O.1    Liu, Y.2    Ruan, Y.3    Xu, Z.C.4    Schantz, L.5    He, J.J.6
  • 20
    • 22744440922 scopus 로고    scopus 로고
    • Cell death in HIV dementia
    • Mattson, M. P., N. J. Haughey, and A. Nath. 2005. Cell death in HIV dementia. Cell Death Differ. 12 (Suppl. 1): 893-904.
    • (2005) Cell Death Differ , vol.12 , Issue.SUPPL. 1 , pp. 893-904
    • Mattson, M.P.1    Haughey, N.J.2    Nath, A.3
  • 21
    • 14844358547 scopus 로고    scopus 로고
    • HIV-1 tat protein induces a migratory phenotype in human fetal microglia by a CCL2 (MCP-1)-dependent mechanism: Possible role in NeuroAIDS
    • Eugenin, E. A., G. Dyer, T. M. Calderon, and J. W. Berman. 2005. HIV-1 tat protein induces a migratory phenotype in human fetal microglia by a CCL2 (MCP-1)-dependent mechanism: possible role in NeuroAIDS. Glia 49: 501-510.
    • (2005) Glia , vol.49 , pp. 501-510
    • Eugenin, E.A.1    Dyer, G.2    Calderon, T.M.3    Berman, J.W.4
  • 23
    • 0033951751 scopus 로고    scopus 로고
    • Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: Protection by memantine
    • Nath, A., N. J. Haughey, M. Jones, C. Anderson, J. E. Bell, and J. D. Geiger. 2000. Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: protection by memantine. Ann. Neurol. 47: 186-194.
    • (2000) Ann. Neurol , vol.47 , pp. 186-194
    • Nath, A.1    Haughey, N.J.2    Jones, M.3    Anderson, C.4    Bell, J.E.5    Geiger, J.D.6
  • 24
    • 2442432175 scopus 로고    scopus 로고
    • HIV secreted protein Tat prevents long-term potentiation in the hippocampal CA1 region
    • Behnisch, T., W. Francesconi, and P. P. Sanna. 2004. HIV secreted protein Tat prevents long-term potentiation in the hippocampal CA1 region. Brain Res. 1012: 187-189.
    • (2004) Brain Res , vol.1012 , pp. 187-189
    • Behnisch, T.1    Francesconi, W.2    Sanna, P.P.3
  • 25
    • 0141726832 scopus 로고    scopus 로고
    • HIV-1 Tat protein up-regulates inflammatory mediators and induces monocyte invasion into the brain
    • Pu, H., J. Tian, G. Flora, Y. W. Lee, A. Nath, B. Hennig, and M. Toborek. 2003. HIV-1 Tat protein up-regulates inflammatory mediators and induces monocyte invasion into the brain. Mol. Cell. Neurosci. 24: 224-237.
    • (2003) Mol. Cell. Neurosci , vol.24 , pp. 224-237
    • Pu, H.1    Tian, J.2    Flora, G.3    Lee, Y.W.4    Nath, A.5    Hennig, B.6    Toborek, M.7
  • 26
    • 0031697077 scopus 로고    scopus 로고
    • HIV-1 Tat molecular diversity and induction of TNF-α: Implications for HIV-induced neurological disease
    • Mayne, M., A. C. Bratanich, P. Chen, F. Rana, A. Nath, and C. Power. 1998. HIV-1 Tat molecular diversity and induction of TNF-α: implications for HIV-induced neurological disease. Neuroimmunomodulation 5: 184-192.
    • (1998) Neuroimmunomodulation , vol.5 , pp. 184-192
    • Mayne, M.1    Bratanich, A.C.2    Chen, P.3    Rana, F.4    Nath, A.5    Power, C.6
  • 27
    • 0037131393 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 (HIV-1) Tat induces nitric-oxide synthase in human astroglia
    • Liu, X., M. Jana, S. Dasgupta, S. Koka, J. He, C. Wood, and K. Pahan. 2002. Human immunodeficiency virus type 1 (HIV-1) Tat induces nitric-oxide synthase in human astroglia. J. Biol. Chem. 277: 39312-39319.
    • (2002) J. Biol. Chem , vol.277 , pp. 39312-39319
    • Liu, X.1    Jana, M.2    Dasgupta, S.3    Koka, S.4    He, J.5    Wood, C.6    Pahan, K.7
  • 28
    • 0033378437 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 TAT protein induces adhesion molecule expression in astrocytes
    • Woodman, S. E., E. N. Benveniste, A. Nath, and J. W. Berman. 1999. Human immunodeficiency virus type 1 TAT protein induces adhesion molecule expression in astrocytes. J. Neurovirol. 5: 678-684.
    • (1999) J. Neurovirol , vol.5 , pp. 678-684
    • Woodman, S.E.1    Benveniste, E.N.2    Nath, A.3    Berman, J.W.4
  • 30
    • 0028261146 scopus 로고
    • Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia
    • Griffin, D. E., S. L. Wesselingh, and J. C. McArthur. 1994. Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia. Ann. Neurol. 35: 592-597.
    • (1994) Ann. Neurol , vol.35 , pp. 592-597
    • Griffin, D.E.1    Wesselingh, S.L.2    McArthur, J.C.3
  • 31
    • 0037000396 scopus 로고    scopus 로고
    • Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier
    • Fiala, M., Q. N. Liu, J. Sayre, V. Pop, V. Brahmandam, M. C. Graves, and H. V. Vinters. 2002. Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier. Eur. J. Clin. Invest. 32: 360-371.
    • (2002) Eur. J. Clin. Invest , vol.32 , pp. 360-371
    • Fiala, M.1    Liu, Q.N.2    Sayre, J.3    Pop, V.4    Brahmandam, V.5    Graves, M.C.6    Vinters, H.V.7
  • 32
    • 21044442392 scopus 로고    scopus 로고
    • Prostaglandins and cyclooxygenases in glial cells during brain inflammation
    • Tzeng, S. F., H. Y. Hsiao, and O. T. Mak. 2005. Prostaglandins and cyclooxygenases in glial cells during brain inflammation. Curr. Drug Targets Inflamm. Allergy. 4: 335-340.
    • (2005) Curr. Drug Targets Inflamm. Allergy , vol.4 , pp. 335-340
    • Tzeng, S.F.1    Hsiao, H.Y.2    Mak, O.T.3
  • 34
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith, W. L., D. L. DeWitt, and R. M. Garavito. 2000. Cyclooxygenases: structural, cellular, and molecular biology. Annu. Rev. Biochem. 69: 145-182.
    • (2000) Annu. Rev. Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 35
    • 0027290813 scopus 로고
    • Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
    • Yamagata, K., K. I. Andreasson, W. E. Kaufmann, C. A. Barnes, and P. F. Worley. 1993. Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 11: 371-386.
    • (1993) Neuron , vol.11 , pp. 371-386
    • Yamagata, K.1    Andreasson, K.I.2    Kaufmann, W.E.3    Barnes, C.A.4    Worley, P.F.5
  • 36
    • 0029595394 scopus 로고
    • Transcriptional roles of nuclear factor κB and nuclear factor- interleukin-6 in the tumor necrosis factor α-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells
    • Yamamoto, K., T. Arakawa, N. Ueda, and S. Yamamoto. 1995. Transcriptional roles of nuclear factor κB and nuclear factor- interleukin-6 in the tumor necrosis factor α-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells. J. Biol. Chem. 270: 31315-31320.
    • (1995) J. Biol. Chem , vol.270 , pp. 31315-31320
    • Yamamoto, K.1    Arakawa, T.2    Ueda, N.3    Yamamoto, S.4
  • 37
    • 0035830861 scopus 로고    scopus 로고
    • Redundancy in the signaling pathways and promoter elements regulating cyclooxygenase-2 gene expression in endotoxin-treated macrophage/ monocytic cells
    • Mestre, J. R., P. J. Mackrell, D. E. Rivadeneira, P. P. Stapleton, T. Tanabe, and J. M. Daly. 2001. Redundancy in the signaling pathways and promoter elements regulating cyclooxygenase-2 gene expression in endotoxin-treated macrophage/ monocytic cells. J. Biol. Chem. 276: 3977-3982.
    • (2001) J. Biol. Chem , vol.276 , pp. 3977-3982
    • Mestre, J.R.1    Mackrell, P.J.2    Rivadeneira, D.E.3    Stapleton, P.P.4    Tanabe, T.5    Daly, J.M.6
  • 38
    • 0034604683 scopus 로고    scopus 로고
    • An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes
    • Iniguez, M. A., S. Martinez-Martinez, C. Punzon, J. M. Redondo, and M. Fresno. 2000. An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes. J. Biol. Chem. 275: 23627-23635.
    • (2000) J. Biol. Chem , vol.275 , pp. 23627-23635
    • Iniguez, M.A.1    Martinez-Martinez, S.2    Punzon, C.3    Redondo, J.M.4    Fresno, M.5
  • 39
    • 0035809312 scopus 로고    scopus 로고
    • Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: Roles of the nuclear factor of activated T cells and cyclooxygenase 2
    • Hernandez, G. L., O. V. Volpert, M. A. Iniguez, E. Lorenzo, S. Martinez-Martinez, R. Grau, M. Fresno, and J. M. Redondo. 2001. Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2. J. Exp. Med. 193: 607-620.
    • (2001) J. Exp. Med , vol.193 , pp. 607-620
    • Hernandez, G.L.1    Volpert, O.V.2    Iniguez, M.A.3    Lorenzo, E.4    Martinez-Martinez, S.5    Grau, R.6    Fresno, M.7    Redondo, J.M.8
  • 40
    • 15444339428 scopus 로고    scopus 로고
    • Ceramide regulates the transcription of cyclooxygenase-2: Evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways
    • Subbaramaiah, K., W. J. Chung, and A. J. Dannenberg. 1998. Ceramide regulates the transcription of cyclooxygenase-2: evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways. J. Biol. Chem. 273: 32943-32949.
    • (1998) J. Biol. Chem , vol.273 , pp. 32943-32949
    • Subbaramaiah, K.1    Chung, W.J.2    Dannenberg, A.J.3
  • 41
    • 0141483523 scopus 로고    scopus 로고
    • Transcriptional regulation by calcium, calcineurin, and NFAT
    • Hogan, P. G., L. Chen, J. Nardone, and A. Rao. 2003. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev. 17: 2205-2232.
    • (2003) Genes Dev , vol.17 , pp. 2205-2232
    • Hogan, P.G.1    Chen, L.2    Nardone, J.3    Rao, A.4
  • 42
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang, L., and M. Karin. 2001. Mammalian MAP kinase signalling cascades. Nature 410: 37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 43
    • 23244456865 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-κB and activating protein-1 mediated mechanism
    • Alvarez, S., M. J. Serramia, M. Fresno, and M. Munoz-Fernandez. 2005. Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-κB and activating protein-1 mediated mechanism. J. Neurochem. 94: 850-861.
    • (2005) J. Neurochem , vol.94 , pp. 850-861
    • Alvarez, S.1    Serramia, M.J.2    Fresno, M.3    Munoz-Fernandez, M.4
  • 44
    • 0033623371 scopus 로고    scopus 로고
    • 2 synthesis in human neuroblastoma cells: Involvement of p38 mitogen-activated protein kinase and nuclear factor-κB
    • 2 synthesis in human neuroblastoma cells: involvement of p38 mitogen-activated protein kinase and nuclear factor-κB. J. Neurochem. 75: 2020-2028.
    • (2000) J. Neurochem , vol.75 , pp. 2020-2028
    • Fiebich, B.L.1    Mueksch, B.2    Boehringer, M.3    Hull, M.4
  • 45
    • 1842287996 scopus 로고    scopus 로고
    • CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription
    • Sune, C., T. Hayashi, Y. Liu, W. S. Lane, R. A. Young, and M. A. Garcia-Blanco. 1997. CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription. Mol. Cell. Biol. 17: 6029-6039.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 6029-6039
    • Sune, C.1    Hayashi, T.2    Liu, Y.3    Lane, W.S.4    Young, R.A.5    Garcia-Blanco, M.A.6
  • 46
    • 0027173483 scopus 로고
    • JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers
    • Deng, T., and M. Karin. 1993. JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers. Genes Dev. 7: 479-490.
    • (1993) Genes Dev , vol.7 , pp. 479-490
    • Deng, T.1    Karin, M.2
  • 47
    • 0028030884 scopus 로고
    • Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription
    • Petrak, D., S. A. Memon, M. J. Birrer, J. D. Ashwell, and C. M. Zacharchuk. 1994. Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription. J. Immunol. 153: 2046-2051.
    • (1994) J. Immunol , vol.153 , pp. 2046-2051
    • Petrak, D.1    Memon, S.A.2    Birrer, M.J.3    Ashwell, J.D.4    Zacharchuk, C.M.5
  • 48
    • 33744808241 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Tat increases cooperation between AP-1 and NFAT transcription factors in T cells
    • Hidalgo-Estevez, A. M., E. Gonzalez, C. Punzon, and M. Fresno. 2006. Human immunodeficiency virus type 1 Tat increases cooperation between AP-1 and NFAT transcription factors in T cells. J. Gen. Virol. 87: 1603-1612.
    • (2006) J. Gen. Virol , vol.87 , pp. 1603-1612
    • Hidalgo-Estevez, A.M.1    Gonzalez, E.2    Punzon, C.3    Fresno, M.4
  • 49
    • 4444333049 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
    • Minghetti, L. 2004. Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases. J. Neuropathol. Exp. Neurol. 63: 901-910.
    • (2004) J. Neuropathol. Exp. Neurol , vol.63 , pp. 901-910
    • Minghetti, L.1
  • 50
    • 10344253813 scopus 로고    scopus 로고
    • Internalization of exogenous human immunodeficiency virus-1 protein, Tat, by KG-1 oligodendroglioma cells followed by stimulation of DNA replication initiated at the JC virus origin
    • Daniel, D. C., Y. Kinoshita, M. A. Khan, L. D. Valle, K. Khalili, J. Rappaport, and E. M. Johnson. 2004. Internalization of exogenous human immunodeficiency virus-1 protein, Tat, by KG-1 oligodendroglioma cells followed by stimulation of DNA replication initiated at the JC virus origin. DNA Cell Biol. 23: 858 - 867.
    • (2004) DNA Cell Biol , vol.23 , pp. 858-867
    • Daniel, D.C.1    Kinoshita, Y.2    Khan, M.A.3    Valle, L.D.4    Khalili, K.5    Rappaport, J.6    Johnson, E.M.7
  • 51
    • 0032750459 scopus 로고    scopus 로고
    • Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1
    • Bajetto, A., R. Bonavia, S. Barbero, P. Piccioli, A. Costa, T. Florio, and G. Schettini. 1999. Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1. J. Neurochem. 73: 2348-2357.
    • (1999) J. Neurochem , vol.73 , pp. 2348-2357
    • Bajetto, A.1    Bonavia, R.2    Barbero, S.3    Piccioli, P.4    Costa, A.5    Florio, T.6    Schettini, G.7
  • 53
    • 3142673373 scopus 로고    scopus 로고
    • Multiple actions of the human immunodeficiency virus type-1 Tat protein on microglial cell functions
    • Minghetti, L., S. Visentin, M. Patrizio, L. Franchini, M. A. Ajmone-Cat, and G. Levi. 2004. Multiple actions of the human immunodeficiency virus type-1 Tat protein on microglial cell functions. Neurochem. Res. 29: 965-978.
    • (2004) Neurochem. Res , vol.29 , pp. 965-978
    • Minghetti, L.1    Visentin, S.2    Patrizio, M.3    Franchini, L.4    Ajmone-Cat, M.A.5    Levi, G.6
  • 54
    • 0027955076 scopus 로고
    • HIV displays its coat of arms
    • Lipton, S. A. 1994. HIV displays its coat of arms. Nature 367: 113-114.
    • (1994) Nature , vol.367 , pp. 113-114
    • Lipton, S.A.1
  • 55
    • 0028847323 scopus 로고
    • The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid
    • Dreyer, E. B., and S. A. Lipton. 1995. The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid. Eur. J. Neurosci. 7: 2502-2507.
    • (1995) Eur. J. Neurosci , vol.7 , pp. 2502-2507
    • Dreyer, E.B.1    Lipton, S.A.2
  • 56
    • 0034637038 scopus 로고    scopus 로고
    • Apoptosis induced by gp120 in the neocortex of rat involves enhanced expression of cyclooxygenase type 2 and is prevented by NMDA receptor antagonists and by the 21-aminosteroid U-74389G
    • Corasaniti, M. T., M. C. Strongoli, S. Piccirilli, R. Nistico, A. Costa, A. Bilotta, P. Turano, A. Finazzi-Agro, and G. Bagetta. 2000. Apoptosis induced by gp120 in the neocortex of rat involves enhanced expression of cyclooxygenase type 2 and is prevented by NMDA receptor antagonists and by the 21-aminosteroid U-74389G. Biochem. Biophys. Res. Commun. 274: 664-669.
    • (2000) Biochem. Biophys. Res. Commun , vol.274 , pp. 664-669
    • Corasaniti, M.T.1    Strongoli, M.C.2    Piccirilli, S.3    Nistico, R.4    Costa, A.5    Bilotta, A.6    Turano, P.7    Finazzi-Agro, A.8    Bagetta, G.9
  • 58
    • 18644380977 scopus 로고    scopus 로고
    • Pertussis toxin (PTX) B subunit and the nontoxic PTX mutant PT9K/129G inhibit Tat-induced TGF-β production by NK cells and TGF-β-mediated NK cell apoptosis
    • Zocchi, M. R., P. Contini, M. Alfano, and A. Poggi. 2005. Pertussis toxin (PTX) B subunit and the nontoxic PTX mutant PT9K/129G inhibit Tat-induced TGF-β production by NK cells and TGF-β-mediated NK cell apoptosis. J. Immunol. 174: 6054-6061.
    • (2005) J. Immunol , vol.174 , pp. 6054-6061
    • Zocchi, M.R.1    Contini, P.2    Alfano, M.3    Poggi, A.4
  • 59
    • 0034909804 scopus 로고    scopus 로고
    • HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity
    • Haughey, N. J., A. Nath, M. P. Mattson, J. T. Slevin, and J. D. Geiger. 2001. HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity. J. Neurochem. 78: 457-467.
    • (2001) J. Neurochem , vol.78 , pp. 457-467
    • Haughey, N.J.1    Nath, A.2    Mattson, M.P.3    Slevin, J.T.4    Geiger, J.D.5
  • 61
    • 34447535456 scopus 로고    scopus 로고
    • HIV-1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in astrocytoma cells through a nuclear factor-κB-dependent mechanism
    • Alvarez, S., M. J. Serramia, M. Fresno, and M. A. Munoz-Fernandez. 2007. HIV-1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in astrocytoma cells through a nuclear factor-κB-dependent mechanism. Neuromolecular Med. 9: 179-193.
    • (2007) Neuromolecular Med , vol.9 , pp. 179-193
    • Alvarez, S.1    Serramia, M.J.2    Fresno, M.3    Munoz-Fernandez, M.A.4
  • 62
    • 0033546424 scopus 로고    scopus 로고
    • Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes: A hit and run phenomenon
    • Nath, A., K. Conant, P. Chen, C. Scott, and E. O. Major. 1999. Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes: a hit and run phenomenon. J. Biol. Chem. 274: 17098-17102.
    • (1999) J. Biol. Chem , vol.274 , pp. 17098-17102
    • Nath, A.1    Conant, K.2    Chen, P.3    Scott, C.4    Major, E.O.5
  • 63
    • 0030884230 scopus 로고    scopus 로고
    • The Tat protein of HIV-1 induces tumor necrosis factor-α production: Implications for HIV-1-associated neurological diseases
    • Chen, P., M. Mayne, C. Power, and A. Nath. 1997. The Tat protein of HIV-1 induces tumor necrosis factor-α production: implications for HIV-1-associated neurological diseases. J. Biol. Chem. 272: 22385-22388.
    • (1997) J. Biol. Chem , vol.272 , pp. 22385-22388
    • Chen, P.1    Mayne, M.2    Power, C.3    Nath, A.4
  • 64
    • 0042112656 scopus 로고    scopus 로고
    • The human immunodeficiency virus type 1 Tat protein up-regulates the promoter activity of the β-chemokine monocyte chemoattractant protein 1 in the human astrocytoma cell line U-87 MG: Role of SP-1, AP-1, and NF-κB consensus sites
    • Lim, S. P., and A. Garzino-Demo. 2000. The human immunodeficiency virus type 1 Tat protein up-regulates the promoter activity of the β-chemokine monocyte chemoattractant protein 1 in the human astrocytoma cell line U-87 MG: role of SP-1, AP-1, and NF-κB consensus sites. J. Virol. 74: 1632-1640.
    • (2000) J. Virol , vol.74 , pp. 1632-1640
    • Lim, S.P.1    Garzino-Demo, A.2
  • 65
    • 0035105022 scopus 로고    scopus 로고
    • Cyclosporin Asensitive signaling pathway involving calcineurin regulates survival of reactive astrocytes
    • Pyrzynska, B., A. Lis, G. Mosieniak, and B. Kaminska. 2001. Cyclosporin Asensitive signaling pathway involving calcineurin regulates survival of reactive astrocytes. Neurochem. Int. 38: 409-415.
    • (2001) Neurochem. Int , vol.38 , pp. 409-415
    • Pyrzynska, B.1    Lis, A.2    Mosieniak, G.3    Kaminska, B.4
  • 66
    • 0037445945 scopus 로고    scopus 로고
    • NFAT4 is expressed in primary astrocytes and activated by glutamate
    • Jones, E. A., D. Sun, L. Kobierski, and A. J. Symes. 2003. NFAT4 is expressed in primary astrocytes and activated by glutamate. J. Neurosci. Res. 72: 191-197.
    • (2003) J. Neurosci. Res , vol.72 , pp. 191-197
    • Jones, E.A.1    Sun, D.2    Kobierski, L.3    Symes, A.J.4
  • 67
    • 0029812855 scopus 로고    scopus 로고
    • Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells
    • Milani, D., M. Mazzoni, P. Borgatti, G. Zauli, L. Cantley, and S. Capitani. 1996. Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells. J. Biol. Chem. 271: 22961-22964.
    • (1996) J. Biol. Chem , vol.271 , pp. 22961-22964
    • Milani, D.1    Mazzoni, M.2    Borgatti, P.3    Zauli, G.4    Cantley, L.5    Capitani, S.6
  • 68
    • 0032515344 scopus 로고    scopus 로고
    • Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-α, and -ε and -ζ isoforms in PC12 cells
    • Borgatti, P., G. Zauli, L. C. Cantley, and S. Capitani. 1998. Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-α, and -ε and -ζ isoforms in PC12 cells. Biochem. Biophys. Res. Commun. 242: 332-337.
    • (1998) Biochem. Biophys. Res. Commun , vol.242 , pp. 332-337
    • Borgatti, P.1    Zauli, G.2    Cantley, L.C.3    Capitani, S.4
  • 70
    • 0141632883 scopus 로고    scopus 로고
    • Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain
    • Bruce-Keller, A. J., A. Chauhan, F. O. Dimayuga, J. Gee, J. N. Keller, and A. Nath. 2003. Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain. J. Neurosci. 23: 8417- 8422.
    • (2003) J. Neurosci , vol.23 , pp. 8417-8422
    • Bruce-Keller, A.J.1    Chauhan, A.2    Dimayuga, F.O.3    Gee, J.4    Keller, J.N.5    Nath, A.6
  • 71
    • 7444220727 scopus 로고    scopus 로고
    • Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes
    • Zhou, B. Y., Y. Liu, B. Kim, Y. Xiao, and J. J. He. 2004. Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes. Mol. Cell. Neurosci. 27: 296-305.
    • (2004) Mol. Cell. Neurosci , vol.27 , pp. 296-305
    • Zhou, B.Y.1    Liu, Y.2    Kim, B.3    Xiao, Y.4    He, J.J.5
  • 72
    • 0035205575 scopus 로고    scopus 로고
    • Mechanisms of prostaglandin E2-induced interleukin-6 release in astrocytes: Possible involvement of EP4-like receptors, p38 mitogen-activated protein kinase and protein kinase C
    • Fiebich, B. L., S. Schleicher, O. Spleiss, M. Czygan, and M. Hull. 2001. Mechanisms of prostaglandin E2-induced interleukin-6 release in astrocytes: possible involvement of EP4-like receptors, p38 mitogen-activated protein kinase and protein kinase C. J. Neurochem. 79: 950-958.
    • (2001) J. Neurochem , vol.79 , pp. 950-958
    • Fiebich, B.L.1    Schleicher, S.2    Spleiss, O.3    Czygan, M.4    Hull, M.5
  • 73
  • 74
    • 33745248085 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is involved in HIV-1 Tat-induced inflammatory responses in the brain
    • Flora, G., H. Pu, B. Hennig, and M. Toborek. 2006. Cyclooxygenase-2 is involved in HIV-1 Tat-induced inflammatory responses in the brain. Neuromolecular Med. 8: 337-352.
    • (2006) Neuromolecular Med , vol.8 , pp. 337-352
    • Flora, G.1    Pu, H.2    Hennig, B.3    Toborek, M.4


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