-
1
-
-
53249121028
-
Proton pump inhibitors: An update of their clinical use and pharmacokinetics
-
Shi S, Klotz U. Proton pump inhibitors: an update of their clinical use and pharmacokinetics. Eur J Clin Pharmacol 2008;64:935-51.
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 935-951
-
-
Shi, S.1
Klotz, U.2
-
2
-
-
46749088691
-
Nocturnal gastroesophageal reflux disease: Issues, implications, and management strategies
-
Johnson DA, Katz PO. Nocturnal gastroesophageal reflux disease: issues, implications, and management strategies. Rev Gastroenterol Disord 2008;8:98-108.
-
(2008)
Rev Gastroenterol Disord
, vol.8
, pp. 98-108
-
-
Johnson, D.A.1
Katz, P.O.2
-
3
-
-
58149181449
-
The demographic characteristics and health-related quality of life in a large cohort of reflux esophagitis patients in Japan with reference to the effect of lansoprazole: The REQUEST study
-
Hongo M, Kinoshita Y, Miwa H, Ashida K. The demographic characteristics and health-related quality of life in a large cohort of reflux esophagitis patients in Japan with reference to the effect of lansoprazole: the REQUEST study. J Gastroenterol 2008;43:920-7.
-
(2008)
J Gastroenterol
, vol.43
, pp. 920-927
-
-
Hongo, M.1
Kinoshita, Y.2
Miwa, H.3
Ashida, K.4
-
4
-
-
65049089659
-
Comparison of the effects of omeprazole and famotidine in treatment of upper abdominal symptoms in patients with reflux esophagitis
-
Kusunoki H, Kusaka M, Kido S, et al. Comparison of the effects of omeprazole and famotidine in treatment of upper abdominal symptoms in patients with reflux esophagitis. J Gastroenterol 2009;44:261-70.
-
(2009)
J Gastroenterol
, vol.44
, pp. 261-270
-
-
Kusunoki, H.1
Kusaka, M.2
Kido, S.3
-
5
-
-
68149119157
-
Acid and non-acid reflux in Japanese patients with non-erosive reflux disease with persistent reflux symptoms, despite taking a double-dose of proton pump inhibitor: A study using combined pH-impedance monitoring
-
Iwakiri K, Kawami N, Sano H, et al. Acid and non-acid reflux in Japanese patients with non-erosive reflux disease with persistent reflux symptoms, despite taking a double-dose of proton pump inhibitor: a study using combined pH-impedance monitoring. J Gastroenterol 2009;44:708-12.
-
(2009)
J Gastroenterol
, vol.44
, pp. 708-712
-
-
Iwakiri, K.1
Kawami, N.2
Sano, H.3
-
6
-
-
68149128387
-
Randomized, parallel, double-blind comparison of the ulcer-healing effects of ilaprazole and omeprazole in the treatment of gastric and duodenal ulcers
-
Ho KY, Kuan A, Zano F, et al. Randomized, parallel, double-blind comparison of the ulcer-healing effects of ilaprazole and omeprazole in the treatment of gastric and duodenal ulcers. J Gastroenterol 2009;44:697-707.
-
(2009)
J Gastroenterol
, vol.44
, pp. 697-707
-
-
Ho, K.Y.1
Kuan, A.2
Zano, F.3
-
7
-
-
63049096015
-
Quinolone-based third-line therapy for Helicobacter pylori eradication
-
Nishizawa T, Suzuki H, Hibi T. Quinolone-based third-line therapy for Helicobacter pylori eradication. J Clin Biochem Nutr 2009;44:119-24.
-
(2009)
J Clin Biochem Nutr
, vol.44
, pp. 119-124
-
-
Nishizawa, T.1
Suzuki, H.2
Hibi, T.3
-
8
-
-
4544267056
-
Interleukin-8 expression in the esophageal mucosa of patients with gastroesophageal reflux disease
-
Yoshida N, Uchiyama K, Kuroda M, et al. Interleukin-8 expression in the esophageal mucosa of patients with gastroesophageal reflux disease. Scand J Gastroenterol 2004;39:816-22.
-
(2004)
Scand J Gastroenterol
, vol.39
, pp. 816-822
-
-
Yoshida, N.1
Uchiyama, K.2
Kuroda, M.3
-
9
-
-
3142757399
-
Mucosal concentrations of proinflammatory cytokines and chemokines at gastric cardia: Implication of Helicobacter pylori infection and gastroesophageal reflux
-
Isomoto H, Nishi Y, Wang A, et al. Mucosal concentrations of proinflammatory cytokines and chemokines at gastric cardia: implication of Helicobacter pylori infection and gastroesophageal reflux. Am J Gastroenterol 2004;99:1063-8.
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 1063-1068
-
-
Isomoto, H.1
Nishi, Y.2
Wang, A.3
-
10
-
-
34948862089
-
Immune and Inflammatory Responses in GERD and Lansoprazole
-
Isomoto H, Nishi Y, Kanazawa Y, et al. Immune and Inflammatory Responses in GERD and Lansoprazole. J Clin Biochem Nutr 2007;41:84-91.
-
(2007)
J Clin Biochem Nutr
, vol.41
, pp. 84-91
-
-
Isomoto, H.1
Nishi, Y.2
Kanazawa, Y.3
-
11
-
-
4644306983
-
Lansoprazole ameliorates intestinal mucosal damage induced by ischemia-reperfusion in rats
-
Ichikawa H, Yoshida N, Takagi T, et al. Lansoprazole ameliorates intestinal mucosal damage induced by ischemia-reperfusion in rats. World J Gastroenterol 2004;10:2814-7.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 2814-2817
-
-
Ichikawa, H.1
Yoshida, N.2
Takagi, T.3
-
12
-
-
33644874756
-
Lansoprazole, a proton pump inhibitor, reduces the severity of indomethacin-induced rat enteritis
-
Kuroda M, Yoshida N, Ichikawa H, et al. Lansoprazole, a proton pump inhibitor, reduces the severity of indomethacin-induced rat enteritis. Int J Mol Med 2006;17:89-93.
-
(2006)
Int J Mol Med
, vol.17
, pp. 89-93
-
-
Kuroda, M.1
Yoshida, N.2
Ichikawa, H.3
-
13
-
-
70350337447
-
Prevention of NSAID-induced small intestinal mucosal injury: Prophylactic potential of lansoprazole
-
Higuchi K, Yoda Y, Amagase K, et al. Prevention of NSAID-induced small intestinal mucosal injury: prophylactic potential of lansoprazole. J Clin Biochem Nutr 2009;45:125-30.
-
(2009)
J Clin Biochem Nutr
, vol.45
, pp. 125-130
-
-
Higuchi, K.1
Yoda, Y.2
Amagase, K.3
-
14
-
-
0034784191
-
Effects of therapy with lansoprazole on intestinal permeability and inflammation in young cystic fibrosis patients
-
Hendriks HJ, van Kreel B, Forget PP. Effects of therapy with lansoprazole on intestinal permeability and inflammation in young cystic fibrosis patients. J Pediatr Gastroenterol Nutr 2001;33:260-5.
-
(2001)
J Pediatr Gastroenterol Nutr
, vol.33
, pp. 260-265
-
-
Hendriks, H.J.1
van Kreel, B.2
Forget, P.P.3
-
15
-
-
25844494436
-
Investigation of the possibility of human-beta defensin 2 (hBD2) as a molecular marker of gastric mucosal inflammation
-
Ohara T, Morishita T, Suzuki H, et al. Investigation of the possibility of human-beta defensin 2 (hBD2) as a molecular marker of gastric mucosal inflammation. Hepatogastroenterology 2005;52:1320-4.
-
(2005)
Hepatogastroenterology
, vol.52
, pp. 1320-1324
-
-
Ohara, T.1
Morishita, T.2
Suzuki, H.3
-
16
-
-
34948863243
-
Anti-inflammatory and anti-oxidative properties of proton pump inhibitors
-
Naito Y. Anti-inflammatory and anti-oxidative properties of proton pump inhibitors. J Clin Biochem Nutr 2007;41:82-83.
-
(2007)
J Clin Biochem Nutr
, vol.41
, pp. 82-83
-
-
Naito, Y.1
-
17
-
-
33646853281
-
Beyond gastric acid reduction: Proton pump inhibitors induce heme oxygenase-1 in gastric and endothelial cells
-
Becker JC, Grosser N, Waltke C, et al. Beyond gastric acid reduction: proton pump inhibitors induce heme oxygenase-1 in gastric and endothelial cells. Biochem Biophys Res Commun 2006;345:1014-21.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 1014-1021
-
-
Becker, J.C.1
Grosser, N.2
Waltke, C.3
-
18
-
-
0024100201
-
Regulation of heme oxygenase gene expression
-
Shibahara S. Regulation of heme oxygenase gene expression. Semin Hematol 1988;25:370-376.
-
(1988)
Semin Hematol
, vol.25
, pp. 370-376
-
-
Shibahara, S.1
-
19
-
-
33646809045
-
Biological implication of heme metabolism
-
Sassa S. Biological implication of heme metabolism. J Clin Biochem Nutr 2006;38:138-155.
-
(2006)
J Clin Biochem Nutr
, vol.38
, pp. 138-155
-
-
Sassa, S.1
-
20
-
-
33644643191
-
The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation
-
Igarashi K, Sun J. The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation. Antioxid Redox Signal 2006;8:107-18.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 107-118
-
-
Igarashi, K.1
Sun, J.2
-
21
-
-
34547676833
-
Lee S, et al. 15d-PGJ2 stimulates HO-1 expression through p38 MAP kinase and Nrf-2 pathway in rat vascular smooth muscle cells
-
Lim HJ, Lee KS, Lee S, et al. 15d-PGJ2 stimulates HO-1 expression through p38 MAP kinase and Nrf-2 pathway in rat vascular smooth muscle cells. Toxicol Appl Pharmacol 2007;223:20-7.
-
(2007)
Toxicol Appl Pharmacol
, vol.223
, pp. 20-27
-
-
Lim, H.J.1
Lee, K.S.2
-
23
-
-
67349252035
-
Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease
-
Morse D, Lin L, Choi AM, Ryter SW. Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease. Free Radic Biol Med 2009;47:1-12.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 1-12
-
-
Morse, D.1
Lin, L.2
Choi, A.M.3
Ryter, S.W.4
-
24
-
-
70349308397
-
Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1
-
Takagi T, Naito Y, Okada H, et al. Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1. J Pharmacol Exp Ther 2009;331:255-64.
-
(2009)
J Pharmacol Exp Ther
, vol.331
, pp. 255-264
-
-
Takagi, T.1
Naito, Y.2
Okada, H.3
-
25
-
-
0034090457
-
A new mechanism for anti-inflammatory actions of proton pump inhibitors-inhibitory effects on neutrophil-endothelial cell interactions
-
Yoshida N, Yoshikawa T, Tanaka Y, et al. A new mechanism for anti-inflammatory actions of proton pump inhibitors-inhibitory effects on neutrophil-endothelial cell interactions. Aliment Pharmacol Ther 2000;14 Suppl 1:74-81.
-
(2000)
Aliment Pharmacol Ther
, vol.14
, Issue.SUPPL. 1
, pp. 74-81
-
-
Yoshida, N.1
Yoshikawa, T.2
Tanaka, Y.3
-
26
-
-
34948843133
-
Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors
-
Handa O, Yoshida N, Fujita N, et al. Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors. Inflamm Res 2006;55:476-80.
-
(2006)
Inflamm Res
, vol.55
, pp. 476-480
-
-
Handa, O.1
Yoshida, N.2
Fujita, N.3
-
27
-
-
33750362795
-
Suppression of proinflammatory cytokine production in macrophages by lansoprazole
-
Hinoki A, Yoshimura K, Fujita K, et al. Suppression of proinflammatory cytokine production in macrophages by lansoprazole. Pediatr Surg Int 2006;22:915-23.
-
(2006)
Pediatr Surg Int
, vol.22
, pp. 915-923
-
-
Hinoki, A.1
Yoshimura, K.2
Fujita, K.3
-
28
-
-
64249110579
-
Proton pump inhibitors exert anti-inflammatory effects and decrease human microglial and monocytic THP-1 cell neurotoxicity
-
Hashioka S, Klegeris A, McGeer PL. Proton pump inhibitors exert anti-inflammatory effects and decrease human microglial and monocytic THP-1 cell neurotoxicity. Exp Neurol 2009;217:177-83.
-
(2009)
Exp Neurol
, vol.217
, pp. 177-183
-
-
Hashioka, S.1
Klegeris, A.2
McGeer, P.L.3
-
29
-
-
67849115751
-
Lansoprazole, a Proton pump inhibitor, suppresses production of tumor necrosis factor-alpha and interleukin-1beta induced by lipopolysaccharide and Helicobacter pylori bacterial components in human monocytic cells via inhibition of activation of nuclear factor-kappaB and extracellular signal-regulated kinase
-
Tanigawa T, Watanabe T, Higuchi K, et al. Lansoprazole, a Proton pump inhibitor, suppresses production of tumor necrosis factor-alpha and interleukin-1beta induced by lipopolysaccharide and Helicobacter pylori bacterial components in human monocytic cells via inhibition of activation of nuclear factor-kappaB and extracellular signal-regulated kinase. J Clin Biochem Nutr 2009;45:86-92.
-
(2009)
J Clin Biochem Nutr
, vol.45
, pp. 86-92
-
-
Tanigawa, T.1
Watanabe, T.2
Higuchi, K.3
-
30
-
-
36849082926
-
Lansoprazole novel effector sites revealed by autoradiography: Relation to Helicobacter pylori, colon, esophagus and others
-
Nakamura M, Matsui H, Serizawa H, Tsuchimoto K. Lansoprazole novel effector sites revealed by autoradiography: relation to Helicobacter pylori, colon, esophagus and others. J Clin Biochem Nutr 2007;41:154-9.
-
(2007)
J Clin Biochem Nutr
, vol.41
, pp. 154-159
-
-
Nakamura, M.1
Matsui, H.2
Serizawa, H.3
Tsuchimoto, K.4
-
31
-
-
11144357585
-
Tumor necrosis factor-alpha-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by rat gastric epithelial cells: Role of reactive oxygen species and nuclear factor-kappaB
-
Handa O, Naito Y, Takagi T, et al. Tumor necrosis factor-alpha-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by rat gastric epithelial cells: role of reactive oxygen species and nuclear factor-kappaB. J Pharmacol Exp Ther 2004;309:670-6.
-
(2004)
J Pharmacol Exp Ther
, vol.309
, pp. 670-676
-
-
Handa, O.1
Naito, Y.2
Takagi, T.3
-
32
-
-
77953364583
-
Inhibition of BACH1 Ameliorates Indomethacin-induced intestinal injury in Mice
-
in press
-
Harusato A, Naito Y, Takagi T, et al. Inhibition of BACH1 ameliorates indomethacin-induced intestinal injury in mice. J Pharm Pharmacol 2010; in press.
-
(2010)
J Pharm Pharmacol
-
-
Harusato, A.1
Naito, Y.2
Takagi, T.3
-
33
-
-
0033543566
-
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene
-
Alam J, Stewart D, Touchard C, et al. Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene. J Biol Chem 1999;274:26071-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 26071-26078
-
-
Alam, J.1
Stewart, D.2
Touchard, C.3
-
34
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K, Wakabayashi N, Katoh Y, et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 1999;13:76-86.
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
-
35
-
-
0034717329
-
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
-
Ishii T, Itoh K, Takahashi S, et al. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem 2000;275:16023-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 16023-16029
-
-
Ishii, T.1
Itoh, K.2
Takahashi, S.3
-
36
-
-
12444257799
-
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles
-
Itoh K, Wakabayashi N, Katoh Y, et al. Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles. Genes Cells 2003;8:379-91.
-
(2003)
Genes Cells
, vol.8
, pp. 379-391
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
-
37
-
-
13244256816
-
Heme oxygenase-1: Redox regulation of a stress protein in lung and cell culture models
-
Ryter SW, Choi AM. Heme oxygenase-1: redox regulation of a stress protein in lung and cell culture models. Antioxid Redox Signal 2005;7:80-91.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 80-91
-
-
Ryter, S.W.1
Choi, A.M.2
-
38
-
-
0033001564
-
Serum antioxidative vitamin levels and lipid peroxidation in gastric carcinoma patients
-
Choi MA, Kim BS, Yu R. Serum antioxidative vitamin levels and lipid peroxidation in gastric carcinoma patients. Cancer Lett 1999;136:89-93.
-
(1999)
Cancer Lett
, vol.136
, pp. 89-93
-
-
Choi, M.A.1
Kim, B.S.2
Yu, R.3
-
39
-
-
0042531793
-
Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway
-
Gong P, Cederbaum AI, Nieto N. Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway. J Biol Chem 2003;278:29693-700.
-
(2003)
J Biol Chem
, vol.278
, pp. 29693-29700
-
-
Gong, P.1
Cederbaum, A.I.2
Nieto, N.3
-
40
-
-
57349131700
-
Heme oxygenase-1 inhibits the proliferation of pancreatic stellate cells by repression of the extracellular signal-regulated kinase1/2 pathway
-
Schwer CI, Guerrero AM, Humar M, et al. Heme oxygenase-1 inhibits the proliferation of pancreatic stellate cells by repression of the extracellular signal-regulated kinase1/2 pathway. J Pharmacol Exp Ther 2008;327:863-71.
-
(2008)
J Pharmacol Exp Ther
, vol.327
, pp. 863-871
-
-
Schwer, C.I.1
Guerrero, A.M.2
Humar, M.3
-
41
-
-
0036839113
-
TGF-beta1 stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells
-
Ning W, Song R, Li C, et al. TGF-beta1 stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells. Am J Physiol Lung Cell Mol Physiol 2002;283:L1094-102.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
-
-
Ning, W.1
Song, R.2
Li, C.3
-
42
-
-
38649142892
-
Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid
-
Pi J, Zhang Q, Woods CG, et al. Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid. Toxicol Appl Pharmacol 2008;226:236-43.
-
(2008)
Toxicol Appl Pharmacol
, vol.226
, pp. 236-243
-
-
Pi, J.1
Zhang, Q.2
Woods, C.G.3
-
43
-
-
0035963293
-
Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:Quinone oxidoreductase1 gene
-
Dhakshinamoorthy S, Jaiswal AK. Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. Oncogene 2001;20:3906-17.
-
(2001)
Oncogene
, vol.20
, pp. 3906-3917
-
-
Dhakshinamoorthy, S.1
Jaiswal, A.K.2
-
44
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, et al. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci U S A 2002;99:11908-13.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
-
45
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
Zhang DD, Hannink M. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol 2003;23:8137-51.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
46
-
-
6344238985
-
Induction of reversible cysteine-targeted protein oxidation by an endogenous electrophile 15-deoxy-delta12,14-prostaglandin J2
-
Ishii T, Uchida K. Induction of reversible cysteine-targeted protein oxidation by an endogenous electrophile 15-deoxy-delta12,14-prostaglandin J2. Chem Res Toxicol 2004;17:1313-22.
-
(2004)
Chem Res Toxicol
, vol.17
, pp. 1313-1322
-
-
Ishii, T.1
Uchida, K.2
-
47
-
-
42149196050
-
Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity
-
Yamamoto T, Suzuki T, Kobayashi A, et al. Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity. Mol Cell Biol 2008;28:2758-70.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 2758-2770
-
-
Yamamoto, T.1
Suzuki, T.2
Kobayashi, A.3
|