Effects of sildenafil on pentylenetetrazol-induced convulsions in mice and amygdala-kindled seizures in rats

Pharmacological Reports

Volumn 62, Issue 2, 2010, Pages 383-391

  Nieoczym, Dorota ^a   Socała, Katarzyna ^a   Rundfeldt, Chris ^b   Wlaź, Piotr ^a  

^a MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

^b Drug ConsultNet   (Germany)

Author keywords

Amygdala kindling; Animal models of epilepsy; Epilepsy; Mice; Pentylenetetrazol; Rats; Sildenafil

Indexed keywords

PENTETRAZOLE; SILDENAFIL; CYCLIC GMP; NITRIC OXIDE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE V INHIBITOR; PIPERAZINE DERIVATIVE; PURINE DERIVATIVE; SULFONE;

AFTERDISCHARGE; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CLONIC SEIZURE; CONTROLLED STUDY; CONVULSION; DOSE RESPONSE; EPILEPTIC DISCHARGE; FOCAL EPILEPSY; KINDLING; MALE; MOUSE; MYOCLONUS SEIZURE; NONHUMAN; RAT; RIGHTING REFLEX; SEIZURE; SEIZURE THRESHOLD; ANIMAL; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; SEIZURES; WISTAR RAT;

AMYGDALA; ANIMALS; CYCLIC GMP; KINDLING, NEUROLOGIC; MALE; MICE; NITRIC OXIDE; PENTYLENETETRAZOLE; PHOSPHODIESTERASE 5 INHIBITORS; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; PURINES; RATS; RATS, WISTAR; SEIZURES; SULFONES;

EID: 77953298414     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(10)70278-4     Document Type: Article

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