Consequences of nitric oxide generation in epileptic-seizure rodent models as studied by in vivo EPR

Magnetic Resonance in Medicine

Volumn 48, Issue 6, 2002, Pages 1051-1056

  Kaneko, Kenshi ^a   Itoh, Kouichi ^b   Berliner, Lawrence J ^c   Miyasaka, Kazuo ^a   Fujii, Hirotada ^d  

^a HOKKAIDO UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^c UNIVERSITY OF DENVER   (United States)

^d SAPPORO MEDICAL UNIVERSITY   (Japan)

Author keywords

EPR; In vivo; NO; NOS; Pentylenetetrazole (PTZ); Seizure

Indexed keywords

ARGININE; BRAIN; DRUG DOSAGE; ELECTRON SPIN RESONANCE SPECTROSCOPY; NITRIC OXIDE; NOBELIUM; PARAMAGNETIC RESONANCE; POSITIVE IONS; RATS; SPECTROMETERS;

CEREBRAL CORTEX; EPILEPTIC SEIZURES; EPILEPTOGENESIS; EPR SPECTROSCOPY; IN-VIVO; OLFACTORY BULBS; PENTYLENETETRAZOLE (PTZ); SEIZURE;

BROMINE COMPOUNDS;

3 BROMO 7 NITROINDAZOLE; N(G) METHYLARGININE; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PENTETRAZOLE;

ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CEREBELLUM; CLONIC SEIZURE; ELECTRON SPIN RESONANCE; ENZYME ASSAY; EPILEPSY; HIPPOCAMPUS; HYPOTHALAMUS; MALE; NONHUMAN; OLFACTORY BULB; RAT; SEIZURE; TONIC SEIZURE;

EID: 0036893511     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10297     Document Type: Article

References (24)

1. Barañano D, Ferris CD, Snyder SH. Atypical neural messengers. Trends Neurosci 2001;24:99-106.
2. Kiss JP, Vizi ES. Nitric oxide: A novel link between synaptic and nonsynaptic transmission. Trends Neurosci 2001;24:211-215.
3. Palmer RMJ, Ress DD, Ashton DS, Moncada S. L-Arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem Biophys Res Commun 1988;153:1251-1256.
4. Bredt DS, Snyder SH. Isolation of nitric oxide synthase, a calmodulin-requiring enzyme. Proc Natl Acad Sci USA 1990;87:682-685.
5. Garthwaite J, Charles SL, Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 1988;336:385-388.
6. Garthwaite J. Glutamate, nitric oxide and cell-cell signaling in the nervous system. Trends Neurosci 1991;14:60-67.
7. Dawson MT, Dawson LV, Dawson L, Snyder HS. A novel neuronal messenger molecule in brain: The free radical, nitric oxide. Ann Neurol 1992;32:297-311.
8. Dawson MT, Snyder HS. Gases as biological messengers: Nitric oxide and carbon monoxide in the brain. J Neurosci 1994;14:5147-5159.
9. De Sarro GB, Donato Di Paola E, De Sarro A, Vidal MJ. Role of nitric oxide in the genesis of excitatory amino acid-induced seizures from the deep prepiriform cortex. Fund Clin Pharmacol 1991;5:503-511.
10. Kaputla I, Uzbay T. L-NAME inhibits pentylenetetrazole and strychnine-induces seizures in mice. Brain Res 1997;753:98-101.
11. Bashkatova V, Vitskova G, Narkevich V, Vanin A, Mikoyan V, Rayevsky K. Nitric oxide content measured by ESR-spectroscopy in the rat brain is increased during pentylenetetrazole-induced seizures. J Molec Neurosci 2000;14:183-190.
12. Vasconcelos A, Marescaux C, Nehlig A. Age-dependent regulation of seizure activity by nitric oxide in the developing rat. Dev Brain Res 1998;107:315-319.
13. Herberg L, Grottick A, Rose I. Nitric oxide synthesis, epileptic seizures and kindling. Psychopharmacology 1995;119:115-123.
14. Przegalinski E, Baran L, Siwanowicz J. The role of nitric oxide in chemically- and electrically-induced seizures in mice. Neurosci Lett 1996;217:145-148.
15. Urbanska EM, Drelewska E, Borowicz KK, Blaszczak P, Kleinrok Z, Czuczwar SJ. N-nitro-L-arginine, a nitric oxide synthase inhibitor, and seizure susceptibility in four seizure models in mice. J Neural Trans 996;103:1145-1152.
16. Ito T, Hori M, Yoshida K, Shimizu M. Effect of anticonvulsants on seizures developing in the course of daily administration of pentetrazol to rats. Eur J Pharmacol 1977;45:165-172.
17. Fujii H, Zhao B, Koscielniak J, Berliner LJ. In vivo EPR studies of the metabolic fate of nitrosobenzene in the mouse. Magn Reson Med 1994;31:77-80.
18. Feelisch M, Noack EA. Nitric oxide (NO) formation from nitrovasodilators occurs independently of hemoglobin or non-heme iron. Eur J Pharmacol 1987;142:465-469.
19. Knowles RG, Merrett M, Salter M, Moncada S. Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat. Biochem J 1990;270:833-836.
20. Komarov AM, Mattson D, Jones MM, Singh PK, Lai C-S. In vivo spin trapping of nitric oxide in mice. Biochem Biophys Res Commun 1993;195:1191-1198.
21. Lai C-S, Komarov AM. Spin trapping of nitric oxide produced in vivo in septic-shock mice. FEBS Lett 1994;345:120-124.
22. Yoshimura T, Yokoyama H, Fujii S, Takayama F, Oikawa K, Kamada H. In vivo EPR detection and imaging of endogenous nitric oxide in lipopolysaccharide-treated mice. Nat Biotechnol 1996;14:992-994.
23. Fujii H, Koscielniak J, Berliner LJ. Determination and characterization of nitric oxide generation in mice by in vivo L-band EPR spectroscopy. Magn Reson Med 1997;38:565-568.
24. Fujii H, Berliner LJ. Ex vivo EPR detection of nitric oxide in brain tissue. Magn Reson Med 1999;42:599-602.