메뉴 건너뛰기




Volumn 34, Issue 2, 2004, Pages 91-103

5′ Adenosine Monophosphate-Activated Protein Kinase, Metabolism and Exercise

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; FATTY ACID; PROTEIN;

EID: 1442332885     PISSN: 01121642     EISSN: None     Source Type: Journal    
DOI: 10.2165/00007256-200434020-00003     Document Type: Review
Times cited : (53)

References (89)
  • 1
    • 0016888751 scopus 로고
    • Biochemical adaptations to endurance exercise in muscle
    • Holloszy JO, Booth FW. Biochemical adaptations to endurance exercise in muscle. Annu Rev Physiol 1976; 38: 273-91
    • (1976) Annu Rev Physiol , vol.38 , pp. 273-291
    • Holloszy, J.O.1    Booth, F.W.2
  • 2
    • 0031717105 scopus 로고    scopus 로고
    • The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell?
    • Hardie DG, Carling D, Carlson M. The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? Annu Rev Biochem 1998; 67: 821-55
    • (1998) Annu Rev Biochem , vol.67 , pp. 821-855
    • Hardie, D.G.1    Carling, D.2    Carlson, M.3
  • 3
    • 0031007065 scopus 로고    scopus 로고
    • The AMP-activated protein kinase: Fuel gauge of the mammalian cell?
    • Hardie DG, Carling D. The AMP-activated protein kinase: fuel gauge of the mammalian cell? Eur J Biochem 1997; 246 (2): 259-73
    • (1997) Eur J Biochem , vol.246 , Issue.2 , pp. 259-273
    • Hardie, D.G.1    Carling, D.2
  • 4
    • 0032792665 scopus 로고    scopus 로고
    • AMP-activated protein kinase, a metabolic master switch: Possible roles in type 2 diabetes
    • Winder WW, Hardie DG. AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am J Physiol 1999; 277 (1 Pt 1): E1-10
    • (1999) Am J Physiol , vol.277 , Issue.1 PART 1
    • Winder, W.W.1    Hardie, D.G.2
  • 5
    • 0034870748 scopus 로고    scopus 로고
    • Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle
    • Winder WW. Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle. J Appl Physiol 2001; 91 (3): 1017-28
    • (2001) J Appl Physiol , vol.91 , Issue.3 , pp. 1017-1028
    • Winder, W.W.1
  • 6
    • 0034219196 scopus 로고    scopus 로고
    • AMP-activated protein kinase: A critical signaling intermediary for exercise-stimulated glucose transport?
    • Goodyear LJ. AMP-activated protein kinase: a critical signaling intermediary for exercise-stimulated glucose transport? Exerc Sport Sci Rev 2000; 28 (3): 113-6
    • (2000) Exerc Sport Sci Rev , vol.28 , Issue.3 , pp. 113-116
    • Goodyear, L.J.1
  • 7
    • 0035986085 scopus 로고    scopus 로고
    • Invited review: Intracellular signaling in contracting skeletal muscle
    • Sakamoto K, Goodyear LJ. Invited review: intracellular signaling in contracting skeletal muscle. J Appl Physiol 2002; 93 (1): 369-83
    • (2002) J Appl Physiol , vol.93 , Issue.1 , pp. 369-383
    • Sakamoto, K.1    Goodyear, L.J.2
  • 8
    • 0036635769 scopus 로고    scopus 로고
    • Targeting the AMP-activated protein kinase for the treatment of type 2 diabetes
    • Musi N, Goodyear LJ. Targeting the AMP-activated protein kinase for the treatment of type 2 diabetes. Curr Drug Targets Immune Endocr Metabol Disord 2002; 2: 119-27
    • (2002) Curr Drug Targets Immune Endocr Metabol Disord , vol.2 , pp. 119-127
    • Musi, N.1    Goodyear, L.J.2
  • 9
    • 0029910018 scopus 로고    scopus 로고
    • Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
    • Hawley SA, Davison M, Woods A, et al. Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase. J Biol Chem 1996; 271 (44): 27879-87
    • (1996) J Biol Chem , vol.271 , Issue.44 , pp. 27879-27887
    • Hawley, S.A.1    Davison, M.2    Woods, A.3
  • 10
    • 0032524622 scopus 로고    scopus 로고
    • Identification of a novel AMP-activated protein kinase β subunit isoform that is highly expressed in skeletal muscle
    • Thornton C, Snowden MA, Carling D. Identification of a novel AMP-activated protein kinase β subunit isoform that is highly expressed in skeletal muscle. J Biol Chem 1998; 273 (20): 12443-50
    • (1998) J Biol Chem , vol.273 , Issue.20 , pp. 12443-12450
    • Thornton, C.1    Snowden, M.A.2    Carling, D.3
  • 11
    • 13344285343 scopus 로고    scopus 로고
    • Mammalian AMP-activated protein kinase subfamily
    • Stapleton D, Mitchelhill KI, Gao G, et al. Mammalian AMP-activated protein kinase subfamily. J Biol Chem 1996; 271 (2): 611-4
    • (1996) J Biol Chem , vol.271 , Issue.2 , pp. 611-614
    • Stapleton, D.1    Mitchelhill, K.I.2    Gao, G.3
  • 12
    • 0000368683 scopus 로고    scopus 로고
    • Exercise induces isoform-specific increase in 5′ AMP-activated protein kinase activity in human skeletal muscle
    • Fujii N, Hayashi T, Hirshman MF, et al. Exercise induces isoform-specific increase in 5′ AMP-activated protein kinase activity in human skeletal muscle. Biochem Biophys Res Commun 2000; 273 (3): 1150-5
    • (2000) Biochem Biophys Res Commun , vol.273 , Issue.3 , pp. 1150-1155
    • Fujii, N.1    Hayashi, T.2    Hirshman, M.F.3
  • 14
    • 0036084141 scopus 로고    scopus 로고
    • Effect of fiber type and nutritional state on AICAR- and contraction-stimulated glucose transport in rat muscle
    • Ai H, Ihlemann J, Hellsten Y, et al. Effect of fiber type and nutritional state on AICAR- and contraction-stimulated glucose transport in rat muscle. Am J Physiol Endocrinol Metab 2002; 282 (6): E1291-300
    • (2002) Am J Physiol Endocrinol Metab , vol.282 , Issue.6
    • Ai, H.1    Ihlemann, J.2    Hellsten, Y.3
  • 15
    • 0035282062 scopus 로고    scopus 로고
    • Post-translational modifications of the β-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization
    • Warden SM, Richardson C, O'Donnell JJ, et al. Post-translational modifications of the β-1 subunit of AMP-activated protein kinase affect enzyme activity and cellular localization. Biochem J 2001; 354 (Pt 2): 275-83
    • (2001) Biochem J , vol.354 , Issue.2 PART , pp. 275-283
    • Warden, S.M.1    Richardson, C.2    O'Donnell, J.J.3
  • 16
    • 0032728266 scopus 로고    scopus 로고
    • Expression of the AMP-activated protein kinase β1 and β2 subunits in skeletal muscle
    • Chen Z, Heierhorst J, Mann RJ, et al. Expression of the AMP-activated protein kinase β1 and β2 subunits in skeletal muscle. FEBS Lett 1999; 460 (2): 343-8
    • (1999) FEBS Lett , vol.460 , Issue.2 , pp. 343-348
    • Chen, Z.1    Heierhorst, J.2    Mann, R.J.3
  • 17
    • 0034654362 scopus 로고    scopus 로고
    • Characterization of AMP-activated protein kinase γ-subunit isoforms and their role in AMP binding
    • Cheung PC, Salt IP, Davies SP, et al. Characterization of AMP-activated protein kinase γ-subunit isoforms and their role in AMP binding. Biochem J 2000; 346 (Pt 3): 659-69
    • (2000) Biochem J , vol.346 , Issue.3 PART , pp. 659-669
    • Cheung, P.C.1    Salt, I.P.2    Davies, S.P.3
  • 18
    • 0036298152 scopus 로고    scopus 로고
    • Effects of endurance training on activity and expression of AMP-activated protein kinase isoforms in rat muscles
    • Durante PE, Mustard KJ, Park SH, et al. Effects of endurance training on activity and expression of AMP-activated protein kinase isoforms in rat muscles. Am J Physiol Endocrinol Metab 2002; 283 (1): E178-86
    • (2002) Am J Physiol Endocrinol Metab , vol.283 , Issue.1
    • Durante, P.E.1    Mustard, K.J.2    Park, S.H.3
  • 19
    • 0034070567 scopus 로고    scopus 로고
    • Metabolic stress and altered glucose transport: Activation of AMP-activated protein kinase as a unifying coupling mechanism
    • Hayashi T, Hirshman MF, Fujii N, et al. Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism. Diabetes 2000; 49: 527-31
    • (2000) Diabetes , vol.49 , pp. 527-531
    • Hayashi, T.1    Hirshman, M.F.2    Fujii, N.3
  • 20
    • 0028845251 scopus 로고
    • 5′-AMP activates the AMP-activated protein kinase cascade, and Ca2+/ calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms
    • Hawley SA, Selbert MA, Goldstein EG, et al. 5′-AMP activates the AMP-activated protein kinase cascade, and Ca2+/ calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms. J Biol Chem 1995; 270 (45): 27186-91
    • (1995) J Biol Chem , vol.270 , Issue.45 , pp. 27186-27191
    • Hawley, S.A.1    Selbert, M.A.2    Goldstein, E.G.3
  • 21
    • 0029561919 scopus 로고
    • 5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase: Studies using bacterially expressed human protein phosphatase-2Cα and native bovine protein phosphatase-2AC
    • Davies SP, Helps NR, Cohen PT, et al. 5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase: studies using bacterially expressed human protein phosphatase-2Cα and native bovine protein phosphatase-2AC. FEBS Lett 1995; 377 (3): 421-5
    • (1995) FEBS Lett , vol.377 , Issue.3 , pp. 421-425
    • Davies, S.P.1    Helps, N.R.2    Cohen, P.T.3
  • 22
    • 0035542970 scopus 로고    scopus 로고
    • AMP-activated protein kinase: The energy charge hypothesis revisited
    • Hardie DG, Hawley SA. AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays 2001; 23 (12): 1112-9
    • (2001) Bioessays , vol.23 , Issue.12 , pp. 1112-1119
    • Hardie, D.G.1    Hawley, S.A.2
  • 23
    • 0033855903 scopus 로고    scopus 로고
    • Dissociation of AMP-activated protein kinase activation and glucose transport in contracting slow-twitch muscle
    • Derave W, Ai H, Ihlemann J, et al. Dissociation of AMP-activated protein kinase activation and glucose transport in contracting slow-twitch muscle. Diabetes 2000; 49 (8): 1281-7
    • (2000) Diabetes , vol.49 , Issue.8 , pp. 1281-1287
    • Derave, W.1    Ai, H.2    Ihlemann, J.3
  • 24
    • 0036430469 scopus 로고    scopus 로고
    • Dissociation of AMPK activity and ACCβ phosphorylation in human muscle during prolonged exercise
    • Wojtaszewski JF, Mourtzakis M, Hillig T, et al. Dissociation of AMPK activity and ACCβ phosphorylation in human muscle during prolonged exercise. Biochem Biophys Res Commun 2002; 298 (3): 309-16
    • (2002) Biochem Biophys Res Commun , vol.298 , Issue.3 , pp. 309-316
    • Wojtaszewski, J.F.1    Mourtzakis, M.2    Hillig, T.3
  • 25
    • 0036064261 scopus 로고    scopus 로고
    • Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA) riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle
    • Wojtaszewski JF, Jorgensen SB, Hellsten Y, et al. Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA) riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle. Diabetes 2002; 51 (2): 284-92
    • (2002) Diabetes , vol.51 , Issue.2 , pp. 284-292
    • Wojtaszewski, J.F.1    Jorgensen, S.B.2    Hellsten, Y.3
  • 26
    • 0037375970 scopus 로고    scopus 로고
    • Regulation of 5′ AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle
    • Wojtaszewski JF, MacDonald C, Nielsen JN, et al. Regulation of 5′ AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle. Am J Physiol Endocrinol Metab 2003; 284 (4): E813-22
    • (2003) Am J Physiol Endocrinol Metab , vol.284 , Issue.4
    • Wojtaszewski, J.F.1    MacDonald, C.2    Nielsen, J.N.3
  • 28
    • 0037219253 scopus 로고    scopus 로고
    • Regulation of glycogen synthase by glucose and glycogen: A possible role for AMP-activated protein kinase
    • Halse R, Fryer LG, McCormack JG, et al. Regulation of glycogen synthase by glucose and glycogen: a possible role for AMP-activated protein kinase. Diabetes 2003; 52 (1): 9-15
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 9-15
    • Halse, R.1    Fryer, L.G.2    McCormack, J.G.3
  • 29
    • 0029978799 scopus 로고    scopus 로고
    • Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise
    • Winder WW, Hardie DG. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am J Physiol 1996; 270 (2 Pt 1): E299-304
    • (1996) Am J Physiol , vol.270 , Issue.2 PART 1
    • Winder, W.W.1    Hardie, D.G.2
  • 30
    • 0030863587 scopus 로고    scopus 로고
    • Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase
    • Rasmussen BB, Winder WW. Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase. J Appl Physiol 1997; 83 (4): 1104-9
    • (1997) J Appl Physiol , vol.83 , Issue.4 , pp. 1104-1109
    • Rasmussen, B.B.1    Winder, W.W.2
  • 31
    • 0031769058 scopus 로고    scopus 로고
    • Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinase
    • Rasmussen BB, Hancock CR, Winder WW. Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinase. J Appl Physiol 1998; 85 (5): 1629-34
    • (1998) J Appl Physiol , vol.85 , Issue.5 , pp. 1629-1634
    • Rasmussen, B.B.1    Hancock, C.R.2    Winder, W.W.3
  • 32
    • 0030901556 scopus 로고    scopus 로고
    • Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase
    • Hutber CA, Hardie DG, Winder WW. Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase. Am J Physiol 1997; 272 (2 Pt 1): E262-6
    • (1997) Am J Physiol , vol.272 , Issue.2 PART 1
    • Hutber, C.A.1    Hardie, D.G.2    Winder, W.W.3
  • 33
    • 0031009673 scopus 로고    scopus 로고
    • Contraction-induced changes in acetyl-CoA carboxylase and 5′-AMP-activated kinase in skeletal muscle
    • Vavvas D, Apazidis A, Saha AK, et al. Contraction-induced changes in acetyl-CoA carboxylase and 5′-AMP-activated kinase in skeletal muscle. J Biol Chem 1997; 272 (20): 13255-61
    • (1997) J Biol Chem , vol.272 , Issue.20 , pp. 13255-13261
    • Vavvas, D.1    Apazidis, A.2    Saha, A.K.3
  • 34
    • 0031849916 scopus 로고    scopus 로고
    • Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport
    • Hayashi T, Hirshman MF, Kurth EJ, et al. Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport. Diabetes 1998; 47 (8): 1369-73
    • (1998) Diabetes , vol.47 , Issue.8 , pp. 1369-1373
    • Hayashi, T.1    Hirshman, M.F.2    Kurth, E.J.3
  • 35
    • 0032865578 scopus 로고    scopus 로고
    • Effect of tension on contraction-induced glucose transport in rat skeletal muscle
    • Ihlemann J, Ploug T, Hellsten Y, et al. Effect of tension on contraction-induced glucose transport in rat skeletal muscle. Am J Physiol 1999; 277 (2 Pt 1): E208-14
    • (1999) Am J Physiol , vol.277 , Issue.2 PART 1
    • Ihlemann, J.1    Ploug, T.2    Hellsten, Y.3
  • 36
    • 0035039274 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise
    • Musi N, Fujii N, Hirshman MF, et al. AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise. Diabetes 2001; 50 (5): 921-7
    • (2001) Diabetes , vol.50 , Issue.5 , pp. 921-927
    • Musi, N.1    Fujii, N.2    Hirshman, M.F.3
  • 37
    • 0034306362 scopus 로고    scopus 로고
    • Isoform-specific and exercise intensity-dependent activation of 5′-AMP-activated protein kinase in human skeletal muscle
    • Wojtaszewski JF, Nielsen P, Hansen BF, et al. Isoform-specific and exercise intensity-dependent activation of 5′-AMP-activated protein kinase in human skeletal muscle. J Physiol 2000; 528 Pt 1: 221-6
    • (2000) J Physiol , vol.528 , Issue.1 PART , pp. 221-226
    • Wojtaszewski, J.F.1    Nielsen, P.2    Hansen, B.F.3
  • 38
    • 0036088360 scopus 로고    scopus 로고
    • Progressive increase in human skeletal muscle AMPKα2 activity and ACC phosphorylation during exercise
    • Stephens TJ, Chen ZP, Canny BJ, et al. Progressive increase in human skeletal muscle AMPKα2 activity and ACC phosphorylation during exercise. Am J Physiol Endocrinol Metab 2002; 282 (3): E688-94
    • (2002) Am J Physiol Endocrinol Metab , vol.282 , Issue.3
    • Stephens, T.J.1    Chen, Z.P.2    Canny, B.J.3
  • 39
    • 0033667964 scopus 로고    scopus 로고
    • AMPK signaling in contracting human skeletal muscle: Acetyl-CoA carboxylase and NO synthase phosphorylation
    • Chen ZP, McConell GK, Michell BJ, et al. AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation. Am J Physiol Endocrinol Metab 2000; 279 (5): E1202-6
    • (2000) Am J Physiol Endocrinol Metab , vol.279 , Issue.5
    • Chen, Z.P.1    McConell, G.K.2    Michell, B.J.3
  • 40
    • 0034999425 scopus 로고    scopus 로고
    • AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle
    • Musi N, Hayashi T, Fujii N, et al. AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle. Am J Physiol 2001; 280 (5): E677-84
    • (2001) Am J Physiol , vol.280 , Issue.5
    • Musi, N.1    Hayashi, T.2    Fujii, N.3
  • 42
    • 0037369214 scopus 로고    scopus 로고
    • A forty-year memoir of research on the regulation of glucose transport into muscle
    • Holloszy JO. A forty-year memoir of research on the regulation of glucose transport into muscle. Am J Physiol Endocrinol Metab 2003; 284 (3): E453-67
    • (2003) Am J Physiol Endocrinol Metab , vol.284 , Issue.3
    • Holloszy, J.O.1
  • 43
    • 0031978984 scopus 로고    scopus 로고
    • Exercise, glucose transport, and insulin sensitivity
    • Goodyear LJ, Kahn BB. Exercise, glucose transport, and insulin sensitivity. Annu Rev Med 1998; 49: 235-61
    • (1998) Annu Rev Med , vol.49 , pp. 235-261
    • Goodyear, L.J.1    Kahn, B.B.2
  • 44
    • 1442340975 scopus 로고    scopus 로고
    • Effects of exercise on glucose transport in skeletal muscle: Glucose transporters and intracellular signaling mechanisms
    • Nose H, Nadel ER, Morimoto T, editors. Carmel (IL): Cooper
    • Goodyear LJ, Hayashi T. Effects of exercise on glucose transport in skeletal muscle: glucose transporters and intracellular signaling mechanisms. In: Nose H, Nadel ER, Morimoto T, editors. The 1997 Nagano Symposium on sports sciences. Carmel (IL): Cooper, 2001: 83-93
    • (2001) The 1997 Nagano Symposium on Sports Sciences , pp. 83-93
    • Goodyear, L.J.1    Hayashi, T.2
  • 45
    • 0031425839 scopus 로고    scopus 로고
    • AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle
    • Merrill GF, Kurth EJ, Hardie DG, et al. AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. Am J Physiol 1997; 273 (36): E1107-12
    • (1997) Am J Physiol , vol.273 , Issue.36
    • Merrill, G.F.1    Kurth, E.J.2    Hardie, D.G.3
  • 46
    • 0026063181 scopus 로고
    • Inhibition by AICA riboside of gluconeogenesis in isolated rat hepatocytes
    • Vincent MF, Marangos PJ, Gruber HE, et al. Inhibition by AICA riboside of gluconeogenesis in isolated rat hepatocytes. Diabetes 1991; 40 (10): 1259-66
    • (1991) Diabetes , vol.40 , Issue.10 , pp. 1259-1266
    • Vincent, M.F.1    Marangos, P.J.2    Gruber, H.E.3
  • 47
    • 0032966874 scopus 로고    scopus 로고
    • Effect of AMPK activation on muscle glucose metabolism in conscious rats
    • Bergeron R, Russell III RR, Young LH, et al. Effect of AMPK activation on muscle glucose metabolism in conscious rats. Am J Physiol 1999; 276 (5 Pt 1): E938-44
    • (1999) Am J Physiol , vol.276 , Issue.5 PART 1
    • Bergeron, R.1    Russell III, R.R.2    Young, L.H.3
  • 48
    • 0032765396 scopus 로고    scopus 로고
    • 5′ AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle
    • Kurth-Kraczek EJ, Hirshman MF, Goodyear LJ, et al. 5′ AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle. Diabetes 1999; 48 (8): 1667-71
    • (1999) Diabetes , vol.48 , Issue.8 , pp. 1667-1671
    • Kurth-Kraczek, E.J.1    Hirshman, M.F.2    Goodyear, L.J.3
  • 49
    • 0024454449 scopus 로고
    • Increased adenosine concentration in blood from ischemic myocardium by AICA riboside: Effects on flow, granulocytes, and injury
    • Gruber HE, Hoffer ME, McAllister DR, et al. Increased adenosine concentration in blood from ischemic myocardium by AICA riboside: effects on flow, granulocytes, and injury. Circulation 1989; 80 (5): 1400-11
    • (1989) Circulation , vol.80 , Issue.5 , pp. 1400-1411
    • Gruber, H.E.1    Hoffer, M.E.2    McAllister, D.R.3
  • 50
    • 0029885660 scopus 로고    scopus 로고
    • Activation of glycogen phosphorylase and glycogenolysis in rat skeletal muscle by AICAR: An activator of AMP-activated protein kinase
    • Young ME, Radda GK, Leighton B. Activation of glycogen phosphorylase and glycogenolysis in rat skeletal muscle by AICAR: an activator of AMP-activated protein kinase. FEBS Lett 1996; 382: 43-7
    • (1996) FEBS Lett , vol.382 , pp. 43-47
    • Young, M.E.1    Radda, G.K.2    Leighton, B.3
  • 51
    • 0035947235 scopus 로고    scopus 로고
    • A role for AMP-activated protein kinase in contraction-and hypoxia-regulated glucose transport in skeletal muscle
    • Mu J, Brozinick Jr JT, Valladares O, et al. A role for AMP-activated protein kinase in contraction-and hypoxia-regulated glucose transport in skeletal muscle. Mol Cell 2001; 7 (5): 1085-94
    • (2001) Mol Cell , vol.7 , Issue.5 , pp. 1085-1094
    • Mu, J.1    Brozinick Jr., J.T.2    Valladares, O.3
  • 52
    • 0036317870 scopus 로고    scopus 로고
    • Effect of AICAR treatment on glycogen metabolism in skeletal muscle
    • Aschenbach WG, Hirshman MF, Fujii N, et al. Effect of AICAR treatment on glycogen metabolism in skeletal muscle. Diabetes 2002; 51 (3): 567-73
    • (2002) Diabetes , vol.51 , Issue.3 , pp. 567-573
    • Aschenbach, W.G.1    Hirshman, M.F.2    Fujii, N.3
  • 53
    • 0035029874 scopus 로고    scopus 로고
    • Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats
    • Bergeron R, Previs SF, Cline GW, et al. Effect of 5-aminoimidazole-4- carboxamide- 1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes 2001; 50 (5): 1076-82
    • (2001) Diabetes , vol.50 , Issue.5 , pp. 1076-1082
    • Bergeron, R.1    Previs, S.F.2    Cline, G.W.3
  • 54
    • 0024335432 scopus 로고
    • The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase
    • Carling D, Hardie DG. The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase. Biochim Biophys Acta 1989; 1012 (1): 81-6
    • (1989) Biochim Biophys Acta , vol.1012 , Issue.1 , pp. 81-86
    • Carling, D.1    Hardie, D.G.2
  • 55
    • 0033948787 scopus 로고    scopus 로고
    • Muscle phosphorylase kinase is not a substrate of AMP-activated protein kinase
    • Beyer A, Kitzerow A, Crute B, et al. Muscle phosphorylase kinase is not a substrate of AMP-activated protein kinase. Biol Chem 2000; 381 (5-6): 457-61
    • (2000) Biol Chem , vol.381 , Issue.5-6 , pp. 457-461
    • Beyer, A.1    Kitzerow, A.2    Crute, B.3
  • 56
    • 0029946455 scopus 로고    scopus 로고
    • Isoform-specific purification and substrate specificity of the 5′ AMP-activated protein kinase
    • Michell BJ, Stapleton D, Mitchelhill KI, et al. Isoform-specific purification and substrate specificity of the 5′ AMP-activated protein kinase. J Biol Chem 1996; 271 (45): 28445-50
    • (1996) J Biol Chem , vol.271 , Issue.45 , pp. 28445-28450
    • Michell, B.J.1    Stapleton, D.2    Mitchelhill, K.I.3
  • 57
    • 0032704115 scopus 로고    scopus 로고
    • Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
    • Holmes BF, Kurth-Kraczek EJ, Winder WW. Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. J Appl Physiol 1999; 87 (5): 1990-5
    • (1999) J Appl Physiol , vol.87 , Issue.5 , pp. 1990-1995
    • Holmes, B.F.1    Kurth-Kraczek, E.J.2    Winder, W.W.3
  • 58
    • 0028967272 scopus 로고
    • Cell-type specificity of inhibition of glycolysis by 5-amino-4- imidazolecarboxamide riboside: Lack of effect in rabbit cardiomyocytes and human erythrocytes, and inhibition in FTO-2B rat hepatoma cells
    • Javaux F, Vincent MF, Wagner DR, et al. Cell-type specificity of inhibition of glycolysis by 5-amino-4-imidazolecarboxamide riboside: lack of effect in rabbit cardiomyocytes and human erythrocytes, and inhibition in FTO-2B rat hepatoma cells. Biochem J 1995; 305 (Pt 3): 913-9
    • (1995) Biochem J , vol.305 , Issue.3 PART , pp. 913-919
    • Javaux, F.1    Vincent, M.F.2    Wagner, D.R.3
  • 59
    • 0036751393 scopus 로고    scopus 로고
    • Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways
    • Hue L, Beauloye C, Marsin AS, et al. Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways. J Mol Cell Cardiol 2002; 34 (9): 1091-7
    • (2002) J Mol Cell Cardiol , vol.34 , Issue.9 , pp. 1091-1097
    • Hue, L.1    Beauloye, C.2    Marsin, A.S.3
  • 60
    • 0034687210 scopus 로고    scopus 로고
    • Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
    • Marsin AS, Bertrand L, Rider MH, et al. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia. Curr Biol 2000; 10 (20): 1247-55
    • (2000) Curr Biol , vol.10 , Issue.20 , pp. 1247-1255
    • Marsin, A.S.1    Bertrand, L.2    Rider, M.H.3
  • 61
    • 0033527643 scopus 로고    scopus 로고
    • Contractile activity modifies Fru-2,6-P2 metabolism in rabbit fast twitch skeletal muscle
    • Cadefau JA, Parra J, Tauler A, et al. Contractile activity modifies Fru-2,6-P2 metabolism in rabbit fast twitch skeletal muscle. J Biol Chem 1999; 274 (45): 31961-6
    • (1999) J Biol Chem , vol.274 , Issue.45 , pp. 31961-31966
    • Cadefau, J.A.1    Parra, J.2    Tauler, A.3
  • 62
    • 0034880181 scopus 로고    scopus 로고
    • Regulation of fatty acid oxidation and glucose metabolism in rat soleus muscle: Effects of AICAR
    • Kaushik VK, Young ME, Dean DJ, et al. Regulation of fatty acid oxidation and glucose metabolism in rat soleus muscle: effects of AICAR. Am J Physiol Endocrinol Metab 2001; 281 (2): E335-40
    • (2001) Am J Physiol Endocrinol Metab , vol.281 , Issue.2
    • Kaushik, V.K.1    Young, M.E.2    Dean, D.J.3
  • 63
    • 0031888070 scopus 로고    scopus 로고
    • Regulation of GLUT4 protein and glycogen synthase during muscle glycogen synthesis after exercise
    • Ivy JL, Kuo CH. Regulation of GLUT4 protein and glycogen synthase during muscle glycogen synthesis after exercise. Acta Physiol Scand 1998; 162 (3): 295-304
    • (1998) Acta Physiol Scand , vol.162 , Issue.3 , pp. 295-304
    • Ivy, J.L.1    Kuo, C.H.2
  • 64
    • 0035155821 scopus 로고    scopus 로고
    • Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D- ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner
    • Buhl ES, Jessen N, Schmitz O, et al. Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner. Diabetes 2001; 50 (1): 12-7
    • (2001) Diabetes , vol.50 , Issue.1 , pp. 12-17
    • Buhl, E.S.1    Jessen, N.2    Schmitz, O.3
  • 65
    • 0033949848 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
    • Winder WW, Holmes BF, Rubink DS, et al. Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle. J Appl Physiol 2000; 88 (6): 2219-26
    • (2000) J Appl Physiol , vol.88 , Issue.6 , pp. 2219-2226
    • Winder, W.W.1    Holmes, B.F.2    Rubink, D.S.3
  • 66
    • 0034685949 scopus 로고    scopus 로고
    • A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle
    • Milan D, Jeon JT, Looft C, et al. A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle. Science 2000; 288 (5469): 1248-51
    • (2000) Science , vol.288 , Issue.5469 , pp. 1248-1251
    • Milan, D.1    Jeon, J.T.2    Looft, C.3
  • 67
    • 0029130484 scopus 로고
    • Malonyl-CoA and carnitine palmitoyltransferase I: An expanding partnership
    • McGarry JD. Malonyl-CoA and carnitine palmitoyltransferase I: an expanding partnership. Biochem Soc Trans 1995; 23 (3): 481-5
    • (1995) Biochem Soc Trans , vol.23 , Issue.3 , pp. 481-485
    • McGarry, J.D.1
  • 68
    • 0032946302 scopus 로고    scopus 로고
    • Malonyl-CoA, fuel sensing, and insulin resistance
    • Ruderman NB, Saha AK, Vavvas D, et aL Malonyl-CoA, fuel sensing, and insulin resistance. Am J Physiol 1999; 276 (1 Pt 1): E1-E18
    • (1999) Am J Physiol , vol.276 , Issue.1 PART 1
    • Ruderman, N.B.1    Saha, A.K.2    Vavvas, D.3
  • 69
    • 0033855904 scopus 로고    scopus 로고
    • Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle
    • Dean D, Daugaard JR, Young ME, et al. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. Diabetes 2000; 49 (8): 1295-300
    • (2000) Diabetes , vol.49 , Issue.8 , pp. 1295-1300
    • Dean, D.1    Daugaard, J.R.2    Young, M.E.3
  • 70
    • 0036087776 scopus 로고    scopus 로고
    • Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle
    • Park SH, Gammon SR, Knippers JD, et al. Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle. J Appl Physiol 2002; 92 (6): 2475-82
    • (2002) J Appl Physiol , vol.92 , Issue.6 , pp. 2475-2482
    • Park, S.H.1    Gammon, S.R.2    Knippers, J.D.3
  • 71
    • 0034637538 scopus 로고    scopus 로고
    • Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4- carboxamide-1-beta-D-ribofuranoside
    • Saha AK, Schwarsin AJ, Roduit R, et al. Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside. J Biol Chem 2000; 275 (32): 24279-83
    • (2000) J Biol Chem , vol.275 , Issue.32 , pp. 24279-24283
    • Saha, A.K.1    Schwarsin, A.J.2    Roduit, R.3
  • 72
    • 0037031840 scopus 로고    scopus 로고
    • Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3- phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise
    • Park H, Kaushik VK, Constant S, et al. Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise. J Biol Chem 2002; 277 (36): 32571-7
    • (2002) J Biol Chem , vol.277 , Issue.36 , pp. 32571-32577
    • Park, H.1    Kaushik, V.K.2    Constant, S.3
  • 73
    • 12244267094 scopus 로고    scopus 로고
    • Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise
    • Yu M, Stepto NK, Chibalin AV, et al. Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise. J Physiol 2003; 546 (Pt 2): 327-35
    • (2003) J Physiol , vol.546 , Issue.2 PART , pp. 327-335
    • Yu, M.1    Stepto, N.K.2    Chibalin, A.V.3
  • 74
    • 15444339308 scopus 로고    scopus 로고
    • Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A
    • Winder WW, Wilson HA, Hardie DG, et al. Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A. J Appl Physiol 1997; 82 (1): 219-25
    • (1997) J Appl Physiol , vol.82 , Issue.1 , pp. 219-225
    • Winder, W.W.1    Wilson, H.A.2    Hardie, D.G.3
  • 75
    • 0035580981 scopus 로고    scopus 로고
    • Malonyl-CoA decarboxylase is not a substrate of AMP-activated protein kinase in rat fast-twitch skeletal muscle or an islet cell line
    • Habinowski SA, Hirshman M, Sakamoto K, et al. Malonyl-CoA decarboxylase is not a substrate of AMP-activated protein kinase in rat fast-twitch skeletal muscle or an islet cell line. Arch Biochem Biophys 2001; 396 (1): 71-9
    • (2001) Arch Biochem Biophys , vol.396 , Issue.1 , pp. 71-79
    • Habinowski, S.A.1    Hirshman, M.2    Sakamoto, K.3
  • 76
    • 0041883026 scopus 로고    scopus 로고
    • The glucose-fatty acid cycle in skeletal muscle at rest and during exercise
    • Maughan RJ, Shisheva A, editors. Aberdeen: Human Kinetics Publishers Inc.
    • Spriet LL, Dyck DJ. The glucose-fatty acid cycle in skeletal muscle at rest and during exercise. In: Maughan RJ, Shisheva A, editors. Biochemistry of exercise. Aberdeen: Human Kinetics Publishers Inc., 2003: 127-56
    • (2003) Biochemistry of Exercise , pp. 127-156
    • Spriet, L.L.1    Dyck, D.J.2
  • 77
    • 0037025356 scopus 로고    scopus 로고
    • AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling
    • Bolster DR, Crozier SJ, Kimball SJ, et al. AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling. J Biol Chem 2002; 277 (27): 23977-80
    • (2002) J Biol Chem , vol.277 , Issue.27 , pp. 23977-23980
    • Bolster, D.R.1    Crozier, S.J.2    Kimball, S.J.3
  • 78
    • 0001171879 scopus 로고    scopus 로고
    • Regulation of gene expression in skeletal muscle by contractile activity
    • Williams RS, Neufer PD. Regulation of gene expression in skeletal muscle by contractile activity. Handbook Physiol 1999; 12: 1124-50
    • (1999) Handbook Physiol , vol.12 , pp. 1124-1150
    • Williams, R.S.1    Neufer, P.D.2
  • 79
    • 0034863102 scopus 로고    scopus 로고
    • Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase
    • Zheng D, MacLean PS, Pohnert SC, et al. Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase. J Appl Physiol 2001; 91 (3): 1073-83
    • (2001) J Appl Physiol , vol.91 , Issue.3 , pp. 1073-1083
    • Zheng, D.1    MacLean, P.S.2    Pohnert, S.C.3
  • 80
    • 0034014002 scopus 로고    scopus 로고
    • Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro
    • Ojuka EO, Nolte LA, Holloszy JO. Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro. J Appl Physiol 2000; 88 (3): 1072-5
    • (2000) J Appl Physiol , vol.88 , Issue.3 , pp. 1072-1075
    • Ojuka, E.O.1    Nolte, L.A.2    Holloszy, J.O.3
  • 81
    • 0036081167 scopus 로고    scopus 로고
    • Regulation of GLUT4 biogenesis in muscle; evidence for involvement of AMPK and Ca2+
    • Ojuka EO, Jones TE, Nolte LA, et al. Regulation of GLUT4 biogenesis in muscle; evidence for involvement of AMPK and Ca2+. Am J Physiol Endocrinol Metab 2002; 282 (5); E1008-13
    • (2002) Am J Physiol Endocrinol Metab , vol.282 , Issue.5
    • Ojuka, E.O.1    Jones, T.E.2    Nolte, L.A.3
  • 82
    • 0033830770 scopus 로고    scopus 로고
    • UCP-3 expression in skeletal muscle: Effects of exercise, hypoxia, and AMP-activated protein kinase
    • Zhou M, Lin BZ, Coughlin S, et al. UCP-3 expression in skeletal muscle: effects of exercise, hypoxia, and AMP-activated protein kinase. Am J Physiol Endocrinol Metab 2000; 279 (3): E622-9
    • (2000) Am J Physiol Endocrinol Metab , vol.279 , Issue.3
    • Zhou, M.1    Lin, B.Z.2    Coughlin, S.3
  • 83
    • 0036889017 scopus 로고    scopus 로고
    • AMP-activated protein kinase activates transcription of the UCP3 and HKII genes in rat skeletal muscle
    • Stoppani J, Hildebrandt AL, Sakamoto K, et al. AMP-activated protein kinase activates transcription of the UCP3 and HKII genes in rat skeletal muscle. Am J Physiol Endocrinol Metab 2002; 283 (6): E1239-48
    • (2002) Am J Physiol Endocrinol Metab , vol.283 , Issue.6
    • Stoppani, J.1    Hildebrandt, A.L.2    Sakamoto, K.3
  • 84
    • 0035665594 scopus 로고    scopus 로고
    • Chronic activation of AMP kinase resulls in NRF-1 activation and mitochondrial biogenesis
    • Bergeron R, Ren JM, Cadman KS, et al. Chronic activation of AMP kinase resulls in NRF-1 activation and mitochondrial biogenesis. Am J Physiol Endocrinol Metab 2001; 281 (6): E1340-6
    • (2001) Am J Physiol Endocrinol Metab , vol.281 , Issue.6
    • Bergeron, R.1    Ren, J.M.2    Cadman, K.S.3
  • 85
    • 0037058977 scopus 로고    scopus 로고
    • AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
    • Zong H, Ren JM, Young LH, et al. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc Natl Acad Sci U S A 2002; 99 (25): 15983-7
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.25 , pp. 15983-15987
    • Zong, H.1    Ren, J.M.2    Young, L.H.3
  • 86
    • 0037066459 scopus 로고    scopus 로고
    • Regulation of mitochondrial biogenesis in skeletal muscle by CaMK
    • Wu H, Kanatous SB, Thurmond FA, et al. Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. Science 2002; 296 (5566): 349-52
    • (2002) Science , vol.296 , Issue.5566 , pp. 349-352
    • Wu, H.1    Kanatous, S.B.2    Thurmond, F.A.3
  • 87
    • 0037185021 scopus 로고    scopus 로고
    • 2 subunit of AMP-activated protein kinase associated with cardiac hypertrophy and Wolff-Parkinson-White syndrome
    • 2 subunit of AMP-activated protein kinase associated with cardiac hypertrophy and Wolff-Parkinson-White syndrome. J Biol Chem 2002; 277 (52): 51017-24
    • (2002) J Biol Chem , vol.277 , Issue.52 , pp. 51017-51024
    • Daniel, T.1    Carling, D.2
  • 88
    • 0035872209 scopus 로고    scopus 로고
    • 2 subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: Evidence for the central role of energy compromise in disease pathogenesis
    • 2 subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis. Hum Mol Genet 2001; 10 (11): 1215-20
    • (2001) Hum Mol Genet , vol.10 , Issue.11 , pp. 1215-1220
    • Blair, E.1    Redwood, C.2    Ashrafian, H.3
  • 89
    • 0035797839 scopus 로고    scopus 로고
    • Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy
    • Tian R, Musi N, D'Agostino J, et al. Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hyper[trophy. Circulation 2001; 104 (14): 1664-9
    • (2001) Circulation , vol.104 , Issue.14 , pp. 1664-1669
    • Tian, R.1    Musi, N.2    D'Agostino, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.