Design and synthesis of novel pyrrolo[2,1-c][1,4]benzodiazepine- lexitropsin conjugates

Journal of Organic Chemistry

Volumn 64, Issue 1, 1999, Pages 290-292

  Damayanthi, Yalamati ^a   Reddy, B S Praveen ^a   Lown, J William ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE DERIVATIVE; LEXITROPSIN;

ARTICLE; CYTOTOXICITY; DRUG CONJUGATION; DRUG DESIGN; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 0033534705     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9812072     Document Type: Article

References (6)

1. (a) Gupta, R. Xie, G.; Lown, J. W. Gene 1994, 149, 81.
2. (b) Gupta, R.; Wang, H.; Huang, L.; Lown, J. W. Anti-Cancer Drug Design 1994, 10, 25.
3. (c) Dervan, P. B.; Baird, E. E. J. Am. Chem. Soc. 1996, 118, 6141.
4. Langley, D. R.; Thurston, D. E. J. Org. Chem. 1987, 52, 91.
5. Kopka, M. L.; Goodsell, D. S.; Baikalov, I.; Grzeskowaik, K.; Cascio, D.; Dickerson, R. E. Biochemistry 1994, 33, 13593.
6. Cheatham, S.; Kook, A.; Hurley, L. H.; Barkley, M. D.; Remers, W. J. Med. Chem. 1988, 31, 583.