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Volumn 25, Issue 5, 2010, Pages 591-599

Role of TGF-β1, its receptor TGFβRII, and Smad proteins in the progression of colorectal cancer

Author keywords

Colorectal cancer; Dendritic cells; Macrophages; Smad proteins; TGF TGF RII

Indexed keywords

CD68 ANTIGEN; CD83 ANTIGEN; HLA DR ANTIGEN; SMAD4 PROTEIN; SMAD7 PROTEIN; T6 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; PROTEIN SERINE THREONINE KINASE; SMAD4 PROTEIN, HUMAN; SMAD7 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA TYPE II RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR; TUMOR PROTEIN;

EID: 77953288010     PISSN: 01791958     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00384-010-0906-9     Document Type: Article
Times cited : (52)

References (35)
  • 1
    • 33748754842 scopus 로고    scopus 로고
    • Transforming growth factor-beta pathway disruption and infiltration of colorectal cancers by intraepithelial lymphocytes
    • Baker K, Chong G, Foulkes WD, Jass JR (2006) Transforming growth factor-beta pathway disruption and infiltration of colorectal cancers by intraepithelial lymphocytes. Histopathology 49:371-380
    • (2006) Histopathology , vol.49 , pp. 371-380
    • Baker, K.1    Chong, G.2    Foulkes, W.D.3    Jass, J.R.4
  • 3
    • 15744372725 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human cancer
    • Elliot RL, Blobe GC (2005) Role of transforming growth factor beta in human cancer. J Clin Oncol 23:2078-2093
    • (2005) J Clin Oncol , vol.23 , pp. 2078-2093
    • Elliot, R.L.1    Blobe, G.C.2
  • 4
    • 34748819999 scopus 로고    scopus 로고
    • TGF-beta receptor downregulation in tumor-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: A retrospective study
    • Bacman D, Merkel S, Croner R, Papadopoulos T, Brueckl W, Dimmler A (2007) TGF-beta receptor downregulation in tumor-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study. BMC Cancer 7:156-166
    • (2007) BMC Cancer , vol.7 , pp. 156-166
    • Bacman, D.1    Merkel, S.2    Croner, R.3    Papadopoulos, T.4    Brueckl, W.5    Dimmler, A.6
  • 5
    • 34547789841 scopus 로고    scopus 로고
    • TGF-β signaling alterations and susceptibility to colorectal cancer
    • doi:10.1093/hmg/dd1486
    • Xu Y, Pashe B (2007) TGF-β signaling alterations and susceptibility to colorectal cancer. Hum Mol Genet 16 (SPEC1):R14-R20. doi:10.1093/hmg/dd1486
    • (2007) Hum Mol Genet , vol.16 , Issue.SPEC. 1
    • Xu, Y.1    Pashe, B.2
  • 6
    • 0031438047 scopus 로고    scopus 로고
    • TGF- β signaling from cell membrane to nucleus via Smad proteins
    • Heldin C-H, Miyazono K, ten Duke P (1997) TGF- β signaling from cell membrane to nucleus via Smad proteins. Nature 390:465-471
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.-H.1    Miyazono, K.2    Ten Duke, P.3
  • 8
    • 0033565626 scopus 로고    scopus 로고
    • Transforming growth factor β1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis
    • Engle SJ, Hoying JB, Boivin GP, Ormsby I, Gartside PS, Doetschman T (1999) Transforming growth factor β1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis. Cancer Res 59:3379-3386
    • (1999) Cancer Res , vol.59 , pp. 3379-3386
    • Engle, S.J.1    Hoying, J.B.2    Boivin, G.P.3    Ormsby, I.4    Gartside, P.S.5    Doetschman, T.6
  • 10
    • 0029740157 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 expression in human colorectal tumors: An independent prognostic marker in a subgroup of poor prognosis patients
    • Robson H, Anderson E, James RD, Schofield PF (1996) Transforming growth factor beta 1 expression in human colorectal tumors: an independent prognostic marker in a subgroup of poor prognosis patients. Br J Cancer 74:753-758
    • (1996) Br J Cancer , vol.74 , pp. 753-758
    • Robson, H.1    Anderson, E.2    James, R.D.3    Schofield, P.F.4
  • 11
    • 0033984978 scopus 로고    scopus 로고
    • Adhesion molecules expressed on homing lymphocytes in model intestinal epithelia
    • Shibahara T, Si-Tahar M, Shaw SK, Madara JL (2000) Adhesion molecules expressed on homing lymphocytes in model intestinal epithelia. Gastroenterology 118:289-298
    • (2000) Gastroenterology , vol.118 , pp. 289-298
    • Shibahara, T.1    Si-Tahar, M.2    Shaw, S.K.3    Madara, J.L.4
  • 13
    • 25144451812 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition (EMT) and colorectal cancer progression
    • Bates RC, Mercurio AM (2005) The epithelial-mesenchymal transition (EMT) and colorectal cancer progression. Cancer Biol Ther 4:365-370
    • (2005) Cancer Biol Ther , vol.4 , pp. 365-370
    • Bates, R.C.1    Mercurio, A.M.2
  • 14
    • 36148960830 scopus 로고    scopus 로고
    • Inflammatory cell infiltration of tumors: Jekyll or hyde
    • Talmadge JE, Donkor M, Scholar E (2007) Inflammatory cell infiltration of tumors: Jekyll or Hyde. Cancer Metast Rev 26:373-400
    • (2007) Cancer Metast Rev , vol.26 , pp. 373-400
    • Talmadge, J.E.1    Donkor, M.2    Scholar, E.3
  • 17
    • 10044294649 scopus 로고    scopus 로고
    • Prognostic significance of mature dendritic cells and factors associated with their accumulation in metastatic liver tumors from colorectal cancer
    • Miygawa S, Soeda J, Takagi S, Miwa S, Ichikawa E, Noike T (2004) Prognostic significance of mature dendritic cells and factors associated with their accumulation in metastatic liver tumors from colorectal cancer. Hum Pathol 35:1392-1396
    • (2004) Hum Pathol , vol.35 , pp. 1392-1396
    • Miygawa, S.1    Soeda, J.2    Takagi, S.3    Miwa, S.4    Ichikawa, E.5    Noike, T.6
  • 18
    • 53949088235 scopus 로고    scopus 로고
    • Recruitment of dendritic cells in human liver with metastases
    • Gulubova M, Manolova I, Cirovski G, Sivrev D (2008) Recruitment of dendritic cells in human liver with metastases. Clin Exp Metast 25:777-785
    • (2008) Clin Exp Metast , vol.25 , pp. 777-785
    • Gulubova, M.1    Manolova, I.2    Cirovski, G.3    Sivrev, D.4
  • 19
    • 77953284589 scopus 로고    scopus 로고
    • UICC 6th ed In: Sobin LH, Wittekind Ch (eds) Wiley-Liss, New York
    • UICC. TNM Classification of Malignant Tumours 6th ed (2002) In: Sobin LH, Wittekind Ch (eds) Wiley-Liss, New York
    • (2002) TNM Classification of Malignant Tumours
  • 20
    • 0031980533 scopus 로고    scopus 로고
    • Immunohistochemical localization of laminin, collagen type IV and heparan sulfate proteoglycan in human colorectal adenocarcinoma: Correlation with local invasive pattern and lymph node metastasis
    • Kioshima T, Kobayashi I, Matsuo K, Ishibashi Y, Miyoshi A, Akashi Y, Sakai H (1998) Immunohistochemical localization of laminin, collagen type IV and heparan sulfate proteoglycan in human colorectal adenocarcinoma: correlation with local invasive pattern and lymph node metastasis. Acta Histochem Cytochem 31:39-47
    • (1998) Acta Histochem Cytochem , vol.31 , pp. 39-47
    • Kioshima, T.1    Kobayashi, I.2    Matsuo, K.3    Ishibashi, Y.4    Miyoshi, A.5    Akashi, Y.6    Sakai, H.7
  • 21
    • 33646065641 scopus 로고    scopus 로고
    • Immunohistochemical assessment of fibronectin and tenascin and their integrin receptors alpha5beta1 and alpha9beta1 in gastric and colorectal cancers with lymph node and liver metastases
    • Gulubova M, Vlaykova T (2006) Immunohistochemical assessment of fibronectin and tenascin and their integrin receptors alpha5beta1 and alpha9beta1 in gastric and colorectal cancers with lymph node and liver metastases. Acta Histochem 108:25-35
    • (2006) Acta Histochem , vol.108 , pp. 25-35
    • Gulubova, M.1    Vlaykova, T.2
  • 22
    • 14844345809 scopus 로고    scopus 로고
    • Transforming growth factor beta can be a parameter of aggressiveness of pT1 colorectal cancer
    • Guzinska-Ustymowicz K, Kemona A (2005) Transforming growth factor beta can be a parameter of aggressiveness of pT1 colorectal cancer. World J Gastroenterol 11:1193-1195
    • (2005) World J Gastroenterol , vol.11 , pp. 1193-1195
    • Guzinska-Ustymowicz, K.1    Kemona, A.2
  • 23
    • 33749259074 scopus 로고    scopus 로고
    • Overexpression of TGF-β1 in esophageal (Barrett's) adenocarcinoma is associated with advanced stage of disease and poor prognosis
    • Von Rahden BHA, Stein HJ, Feith M, Puhringer F, Theisen J, Siewert R, Sarbia M (2006) Overexpression of TGF-β1 in esophageal (Barrett's) adenocarcinoma is associated with advanced stage of disease and poor prognosis. Mol Carcinog 45:786-794
    • (2006) Mol Carcinog , vol.45 , pp. 786-794
    • Von Rahden, B.H.A.1    Stein, H.J.2    Feith, M.3    Puhringer, F.4    Theisen, J.5    Siewert, R.6    Sarbia, M.7
  • 24
    • 42149168576 scopus 로고    scopus 로고
    • Expression of transforming growth factors in hepatocellular carcinoma and its relations with clinicopathological parameters and prognosis
    • Lu Y, Wu L-Q, Li C-S, Wang S-G, Han B (2008) Expression of transforming growth factors in hepatocellular carcinoma and its relations with clinicopathological parameters and prognosis. Hepatobiliary Pancreat Dis Int 7:174-178
    • (2008) Hepatobiliary Pancreat Dis Int , vol.7 , pp. 174-178
    • Lu, Y.1    Wu, L.-Q.2    Li, C.-S.3    Wang, S.-G.4    Han, B.5
  • 25
    • 1842431049 scopus 로고    scopus 로고
    • Expression of Smad7 in hepatocellular carcinoma and dysplastic nodules: Resistance mechanism to transforming growth factor-β
    • Park YN, Chae KJ, Oh B-K, Choi J, Choi KS, Park C (2004) Expression of Smad7 in hepatocellular carcinoma and dysplastic nodules: resistance mechanism to transforming growth factor-β. Hepato-Gastroenterol 51:396-400
    • (2004) Hepato-Gastroenterol , vol.51 , pp. 396-400
    • Park, Y.N.1    Chae, K.J.2    Oh, B.-K.3    Choi, J.4    Choi, K.S.5    Park, C.6
  • 26
    • 0031948084 scopus 로고    scopus 로고
    • A subset of metastatic human colon cancers expresses elevated levels of transforming growth factor β1
    • Picon A, Gold LI, Wang J, Cohen A, Friedman E (1998) A subset of metastatic human colon cancers expresses elevated levels of transforming growth factor β1. Cancer Epidemiol Biomark Prev 7:497-504
    • (1998) Cancer Epidemiol Biomark Prev , vol.7 , pp. 497-504
    • Picon, A.1    Gold, L.I.2    Wang, J.3    Cohen, A.4    Friedman, E.5
  • 27
    • 0027848683 scopus 로고
    • Increased transforming growth factor β expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of meth a sarcoma cells
    • Chang H-L, Gillett N, Figari I, Lopez A, Palladino M, Derynck R (1993) Increased transforming growth factor β expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells. Cancer Res 53:4391-4398
    • (1993) Cancer Res , vol.53 , pp. 4391-4398
    • Chang, H.-L.1    Gillett, N.2    Figari, I.3    Lopez, A.4    Palladino, M.5    Derynck, R.6
  • 28
    • 0006335227 scopus 로고    scopus 로고
    • Elevated serum levels of transforming growth factor- β1 in patients with colorectal carcinoma
    • Shim KS, Kim KH, Han WS, Park EB (1999) Elevated serum levels of transforming growth factor- β1 in patients with colorectal carcinoma. Cancer 85:554-561
    • (1999) Cancer , vol.85 , pp. 554-561
    • Shim, K.S.1    Kim, K.H.2    Han, W.S.3    Park, E.B.4
  • 29
    • 0028230617 scopus 로고
    • Increased expression of transforming growth factor β isoforms and basic fibroblast growth factor in complex hyperplasia and adenocarcinoma of the endometrium: Evidence for paracrine and autocrine action
    • Gold L, Saxena B, Mittalk K, Marmor M, Goswami S, Nactigal L, Kork M, Demopoulos R (1994) Increased expression of transforming growth factor β isoforms and basic fibroblast growth factor in complex hyperplasia and adenocarcinoma of the endometrium: evidence for paracrine and autocrine action. Cancer Res 54:2347-2358
    • (1994) Cancer Res , vol.54 , pp. 2347-2358
    • Gold, L.1    Saxena, B.2    Mittalk, K.3    Marmor, M.4    Goswami, S.5    Nactigal, L.6    Kork, M.7    Demopoulos, R.8
  • 30
    • 0027053058 scopus 로고
    • Immunohistochemical staining for transforming growth factor β1 associates with disease progression in human breast cancer
    • Gorsch S, Memoli V, Stukel T, Gold L, Arrick B (1992) Immunohistochemical staining for transforming growth factor β1 associates with disease progression in human breast cancer. Cancer Res 52:6949-6952
    • (1992) Cancer Res , vol.52 , pp. 6949-6952
    • Gorsch, S.1    Memoli, V.2    Stukel, T.3    Gold, L.4    Arrick, B.5
  • 34
    • 27844514155 scopus 로고    scopus 로고
    • Stable verexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo
    • Javelaud D, Delmas V, Moller M, Sextius P, Andre J, Menashi S, Larue L, Mauviel A (2005) Stable verexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo. Oncogene 24:7624-7629
    • (2005) Oncogene , vol.24 , pp. 7624-7629
    • Javelaud, D.1    Delmas, V.2    Moller, M.3    Sextius, P.4    Andre, J.5    Menashi, S.6    Larue, L.7    Mauviel, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.