메뉴 건너뛰기




Volumn 7, Issue 2, 2008, Pages 174-178

Expression of transforming growth factors in hepatocellular carcinoma and its relations with clinicopathological parameters and prognosis

Author keywords

Carcinoma; Hepatocellular; Immunohistochemistry; Transforming growth factor

Indexed keywords

SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1;

EID: 42149168576     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (18)

References (32)
  • 1
    • 33746002609 scopus 로고    scopus 로고
    • Control of differentiation in progression of epithelial tumors
    • Abelev GI, Lazarevich NL. Control of differentiation in progression of epithelial tumors. Adv Cancer Res 2006;95: 61-113.
    • (2006) Adv Cancer Res , vol.95 , pp. 61-113
    • Abelev, G.I.1    Lazarevich, N.L.2
  • 2
    • 0344586810 scopus 로고    scopus 로고
    • Inhibition of CK2 activity by TGF-beta1 promotes IkappaB-alpha protein stabilization and apoptosis of immortalized hepatocytes
    • Cavin LG, Romieu-Mourez R, Panta GR, Sun J, Factor VM, Thorgeirsson SS, et al. Inhibition of CK2 activity by TGF-beta1 promotes IkappaB-alpha protein stabilization and apoptosis of immortalized hepatocytes. Hepatology 2003; 38:1540-1551.
    • (2003) Hepatology , vol.38 , pp. 1540-1551
    • Cavin, L.G.1    Romieu-Mourez, R.2    Panta, G.R.3    Sun, J.4    Factor, V.M.5    Thorgeirsson, S.S.6
  • 3
    • 0242438167 scopus 로고    scopus 로고
    • Expressions of transforming growth factor (TGF)-beta1 and TGF-beta type II receptor and their relationship with apoptosis during chemical hepatocarcinogenesis in rats
    • Park DY, Sol MY, Suh KS, Shin EC, Kim CH. Expressions of transforming growth factor (TGF)-beta1 and TGF-beta type II receptor and their relationship with apoptosis during chemical hepatocarcinogenesis in rats. Hepatol Res 2003;27:205-213.
    • (2003) Hepatol Res , vol.27 , pp. 205-213
    • Park, D.Y.1    Sol, M.Y.2    Suh, K.S.3    Shin, E.C.4    Kim, C.H.5
  • 4
    • 34047180525 scopus 로고    scopus 로고
    • Smad4 and ERK2 stimulated by transforming growth factor beta1 in rhabdomyosarcoma
    • Guo H, Zhang HY, Wang SL, Ye L, Yang GH, Bu H. Smad4 and ERK2 stimulated by transforming growth factor beta1 in rhabdomyosarcoma. Chin Med J (Engl) 2007;120:515-521.
    • (2007) Chin Med J (Engl) , vol.120 , pp. 515-521
    • Guo, H.1    Zhang, H.Y.2    Wang, S.L.3    Ye, L.4    Yang, G.H.5    Bu, H.6
  • 6
    • 0033570029 scopus 로고    scopus 로고
    • The expression of transforming, growth factor-beta1 is significantly correlated with the expression of vascular endothelial growth factor and poor prognosis of patients with advanced gastric carcinoma
    • Saito H, Tsujitani S, Oka S, Kondo A, Ikeguchi M, Maeta M, et al. The expression of transforming, growth factor-beta1 is significantly correlated with the expression of vascular endothelial growth factor and poor prognosis of patients with advanced gastric carcinoma. Cancer 1999;86:1455-1462.
    • (1999) Cancer , vol.86 , pp. 1455-1462
    • Saito, H.1    Tsujitani, S.2    Oka, S.3    Kondo, A.4    Ikeguchi, M.5    Maeta, M.6
  • 7
    • 0031724451 scopus 로고    scopus 로고
    • Overexpression of transforming growth factor-beta1 in scirrhous carcinoma of the stomach correlates with decreased survival
    • Kinugasa S, Abe S, Tachibana M, Hishikawa Y, Yoshimura H, Monden N, et al. Overexpression of transforming growth factor-beta1 in scirrhous carcinoma of the stomach correlates with decreased survival. Oncology 1998;55:582-587.
    • (1998) Oncology , vol.55 , pp. 582-587
    • Kinugasa, S.1    Abe, S.2    Tachibana, M.3    Hishikawa, Y.4    Yoshimura, H.5    Monden, N.6
  • 8
    • 2342434705 scopus 로고    scopus 로고
    • Prognostic significance of the expression of Smad4 and Smad7 in human gastric carcinomas
    • Kim YH, Lee HS, Lee HJ, Hur K, Kim WH, Bang YJ, et al. Prognostic significance of the expression of Smad4 and Smad7 in human gastric carcinomas. Ann Oncol 2004;15: 574-580.
    • (2004) Ann Oncol , vol.15 , pp. 574-580
    • Kim, Y.H.1    Lee, H.S.2    Lee, H.J.3    Hur, K.4    Kim, W.H.5    Bang, Y.J.6
  • 9
    • 0035233998 scopus 로고    scopus 로고
    • Relation of type II transforming growth factor-beta receptor to hepatic fibrosis and hepatocellular carcinoma
    • Ueno T, Hashimoto O, Kimura R, Torimura T, Kawaguchi T, Nakamura T, et al. Relation of type II transforming growth factor-beta receptor to hepatic fibrosis and hepatocellular carcinoma. Int J Oncol 2001;18:49-55.
    • (2001) Int J Oncol , vol.18 , pp. 49-55
    • Ueno, T.1    Hashimoto, O.2    Kimura, R.3    Torimura, T.4    Kawaguchi, T.5    Nakamura, T.6
  • 10
    • 0038205584 scopus 로고    scopus 로고
    • Expression of c-erbB-2 oncogene protein, epidermal growth factor receptor, and TGF-beta1 in human pancreatic ductal adenocarcinoma
    • Zhang L, Yuan SZ. Expression of c-erbB-2 oncogene protein, epidermal growth factor receptor, and TGF-beta1 in human pancreatic ductal adenocarcinoma. Hepatobiliary Pancreat Dis Int 2002;1:620-623.
    • (2002) Hepatobiliary Pancreat Dis Int , vol.1 , pp. 620-623
    • Zhang, L.1    Yuan, S.Z.2
  • 11
    • 22144490495 scopus 로고    scopus 로고
    • Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis
    • Han G, Lu SL, Li AG, He W, Corless CL, Kulesz-Martin M, et al. Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis. J Clin Invest 2005;115: 1714-1723.
    • (2005) J Clin Invest , vol.115 , pp. 1714-1723
    • Han, G.1    Lu, S.L.2    Li, A.G.3    He, W.4    Corless, C.L.5    Kulesz-Martin, M.6
  • 12
    • 15244340251 scopus 로고    scopus 로고
    • TGFbeta1, back to the future: Revisiting its role as a transforming growth factor
    • Glick AB. TGFbeta1, back to the future: revisiting its role as a transforming growth factor. Cancer Biol Ther 2004;3: 276-283.
    • (2004) Cancer Biol Ther , vol.3 , pp. 276-283
    • Glick, A.B.1
  • 13
    • 33750573332 scopus 로고    scopus 로고
    • Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and [i#in vivo#1i]
    • Andl CD, Fargnoli BB, Okawa T, Bowser M, Takaoka M, Nakagawa H, et al. Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and [i#in vivo#1i]. Cancer Res 2006;66:9878-9885.
    • (2006) Cancer Res , vol.66 , pp. 9878-9885
    • Andl, C.D.1    Fargnoli, B.B.2    Okawa, T.3    Bowser, M.4    Takaoka, M.5    Nakagawa, H.6
  • 14
    • 11844299595 scopus 로고    scopus 로고
    • Association between endogenous gene expression and growth regulation induced by TGF-beta1 in human gastric cancer cells
    • Li X, Zhang YY, Wang Q, Fu SB. Association between endogenous gene expression and growth regulation induced by TGF-beta1 in human gastric cancer cells. World J Gastroenterol 2005;11:61-68.
    • (2005) World J Gastroenterol , vol.11 , pp. 61-68
    • Li, X.1    Zhang, Y.Y.2    Wang, Q.3    Fu, S.B.4
  • 15
    • 33847391646 scopus 로고    scopus 로고
    • Expression of messenger RNA for transforming growth factor-beta1 and for transforming growth factor-beta receptors in peripheral blood of systemic lupus erythematosus patients treated with low doses of quinagolide
    • Hrycek A, Kusmierz D, Dybala T, Swiatkowska L. Expression of messenger RNA for transforming growth factor-beta1 and for transforming growth factor-beta receptors in peripheral blood of systemic lupus erythematosus patients treated with low doses of quinagolide. Autoimmunity 2007;40:23-30.
    • (2007) Autoimmunity , vol.40 , pp. 23-30
    • Hrycek, A.1    Kusmierz, D.2    Dybala, T.3    Swiatkowska, L.4
  • 16
    • 33645333133 scopus 로고    scopus 로고
    • Gefitinib and the modulation of the signaling pathways downstream of epidermal growth factor receptor in human liver cancer cells
    • Okano J, Matsumoto K, Nagahara T, Murawaki Y. Gefitinib and the modulation of the signaling pathways downstream of epidermal growth factor receptor in human liver cancer cells. J Gastroenterol 2006;41:166-176.
    • (2006) J Gastroenterol , vol.41 , pp. 166-176
    • Okano, J.1    Matsumoto, K.2    Nagahara, T.3    Murawaki, Y.4
  • 17
    • 33847731040 scopus 로고    scopus 로고
    • Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells
    • Shiou SR, Singh AB, Moorthy K, Datta PK, Washington MK, Beauchamp RD, et al. Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells. Cancer Res 2007;67:1571-1579.
    • (2007) Cancer Res , vol.67 , pp. 1571-1579
    • Shiou, S.R.1    Singh, A.B.2    Moorthy, K.3    Datta, P.K.4    Washington, M.K.5    Beauchamp, R.D.6
  • 18
    • 33751251034 scopus 로고    scopus 로고
    • Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer
    • Bardeesy N, Cheng KH, Berger JH, Chu GC, Pahler J, Olson P, et al. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. Genes Dev 2006;20:3130-3146.
    • (2006) Genes Dev , vol.20 , pp. 3130-3146
    • Bardeesy, N.1    Cheng, K.H.2    Berger, J.H.3    Chu, G.C.4    Pahler, J.5    Olson, P.6
  • 19
    • 33751247898 scopus 로고    scopus 로고
    • Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression
    • Ijichi H, Chytil A, Gorska AE, Aakre ME, Fujitani Y, Fujitani S, et al. Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression. Genes Dev 2006; 20:3147-3160.
    • (2006) Genes Dev , vol.20 , pp. 3147-3160
    • Ijichi, H.1    Chytil, A.2    Gorska, A.E.3    Aakre, M.E.4    Fujitani, Y.5    Fujitani, S.6
  • 20
    • 32944459015 scopus 로고    scopus 로고
    • Molecular mechanisms of pancreatic carcinogenesis
    • Furukawa T, Sunamura M, Horii A. Molecular mechanisms of pancreatic carcinogenesis. Cancer Sci 2006;97:1-7.
    • (2006) Cancer Sci , vol.97 , pp. 1-7
    • Furukawa, T.1    Sunamura, M.2    Horii, A.3
  • 21
    • 34548575184 scopus 로고    scopus 로고
    • Loss of Smad4 expression predicts liver metastasis in human colorectal cancer
    • Losi L, Bouzourene H, Benhattar J. Loss of Smad4 expression predicts liver metastasis in human colorectal cancer. Oncol Rep 2007;17:1095-1099.
    • (2007) Oncol Rep , vol.17 , pp. 1095-1099
    • Losi, L.1    Bouzourene, H.2    Benhattar, J.3
  • 22
    • 33751086164 scopus 로고    scopus 로고
    • Expression and mutation of SMAD4 in poorly differentiated carcinoma and signet-ring cell carcinoma of the colorectum
    • Seshimo I, Yamamoto H, Mishima H, Kurata A, Suzuki R, Ezumi K, et al. Expression and mutation of SMAD4 in poorly differentiated carcinoma and signet-ring cell carcinoma of the colorectum. J Exp Clin Cancer Res 2006; 25:433-442.
    • (2006) J Exp Clin Cancer Res , vol.25 , pp. 433-442
    • Seshimo, I.1    Yamamoto, H.2    Mishima, H.3    Kurata, A.4    Suzuki, R.5    Ezumi, K.6
  • 25
    • 34249735834 scopus 로고    scopus 로고
    • Chen W, Lam SS, Srinath H, Schiffer CA, Royer WE Jr, Lin K. Competition between Ski and CREB-binding protein for binding to Smad proteins in transforming growth factor-beta signaling. J Biol Chem 2007;282-11365-11376.
    • Chen W, Lam SS, Srinath H, Schiffer CA, Royer WE Jr, Lin K. Competition between Ski and CREB-binding protein for binding to Smad proteins in transforming growth factor-beta signaling. J Biol Chem 2007;282-11365-11376.
  • 26
    • 34247882875 scopus 로고    scopus 로고
    • Restoration of RUNX3 enhances transforming growth factor-beta-dependent p21 expression in a biliary tract cancer cell line
    • Hasegawa K, Yazumi S, Wada M, Sakurai T, Kida M, Yamauchi J, et al. Restoration of RUNX3 enhances transforming growth factor-beta-dependent p21 expression in a biliary tract cancer cell line. Cancer Sci 2007;98:838-843.
    • (2007) Cancer Sci , vol.98 , pp. 838-843
    • Hasegawa, K.1    Yazumi, S.2    Wada, M.3    Sakurai, T.4    Kida, M.5    Yamauchi, J.6
  • 27
    • 34247117728 scopus 로고    scopus 로고
    • Genetic testing in colorectal cancer: Who, when, how and why
    • Davidson NO. Genetic testing in colorectal cancer: who, when, how and why. Keio J Med 2007;56:14-20.
    • (2007) Keio J Med , vol.56 , pp. 14-20
    • Davidson, N.O.1
  • 29
    • 33846326893 scopus 로고    scopus 로고
    • Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression
    • Wang LH, Kim SH, Lee JH, Choi YL, Kim YC, Park TS, et al. Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression. Clin Cancer Res 2007;13: 102-110.
    • (2007) Clin Cancer Res , vol.13 , pp. 102-110
    • Wang, L.H.1    Kim, S.H.2    Lee, J.H.3    Choi, Y.L.4    Kim, Y.C.5    Park, T.S.6
  • 30
    • 33847387472 scopus 로고    scopus 로고
    • Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas
    • Izeradjene K, Combs C, Best M, Gopinathan A, Wagner A, Grady WM, et al. Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas. Cancer Cell 2007;11:229-243.
    • (2007) Cancer Cell , vol.11 , pp. 229-243
    • Izeradjene, K.1    Combs, C.2    Best, M.3    Gopinathan, A.4    Wagner, A.5    Grady, W.M.6
  • 31
    • 34248674918 scopus 로고    scopus 로고
    • Smad4 is essential for down-regulation of E-cadherin induced by TGF-beta in pancreatic cancer cell line PANC-1
    • Takano S, Kanai F, Jazag A, Ijichi H, Yao J, Ogawa H, et al. Smad4 is essential for down-regulation of E-cadherin induced by TGF-beta in pancreatic cancer cell line PANC-1. J Biochem 2007;141:345-351.
    • (2007) J Biochem , vol.141 , pp. 345-351
    • Takano, S.1    Kanai, F.2    Jazag, A.3    Ijichi, H.4    Yao, J.5    Ogawa, H.6
  • 32


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.