Synthesis and biological evaluation of pyrimidine analogs of antimycobacterial purines

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 11, 2010, Pages 3885-3897

  Read, Matthew L ^a   Brændvang, Morten ^a   Miranda, Pedro O ^a   Gundersen, Lise Lotte ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

Antimycobacterials; Fleximers; Pyrimidines

Indexed keywords

2 CHLORO 4 (2 FURYL) 6 (4 METHOXYBENZYLOXY)PYRIMIDINE; 2 CHLORO 6 (2 FURYL) N (4 METHOXYBENZYL) N METHYLPYRIMIDINE 4 AMINE; 2 CHLORO 6 (2 FURYL) N (4 METHOXYBENZYL)PYRIMIDINE 4 AMINE; 2,4 DICHLORO 6 (2 FURYL)PYRIMIDINE; 4 (2 FURYL) 6 (4 METHOXYBENZYLOXY) 5 NITROPYRIMIDINE; 4 (2 FURYL) 6 (4 METHOXYBENZYLOXY)PYRIMIDINE; 4 CHLORO 6 (4 METHOXYBENZYLOXY)PYRIMIDINE; 4 CHLORO 6 (4 METHOXYBENZYLOXY)PYRIMIDINE 5 AMINE; 4,6 DICHLORO N ETHYLPYRIMIDINE 5 AMINE; 4,6 DICHLORO N METHYLPYRIMIDINE 5 AMINE; 6 (2 FURYL) N (4 METHOXYBENZYL) 5 NITROPYRIMIDINE 4 AMINE; 6 (2 FURYL) N (4 METHOXYBENZYL) METHYLPYRIMIDINE 4 AMINE; 6 (2 FURYL) N (4 METHOXYBENZYL) N METHYL 5 NITROPYRIMIDINE 4 AMINE; 6 (2 FURYL) N (4 METHOXYBENZYL)PYRIMIDINE 4 AMINE; 6 (2 FURYL) N4 (4 METHOXYBENZYL) N4 METHYLPYRIMIDINE 4,5 DIAMINE; 6 (2 FURYL) N4 (4 METHOXYBENZYL) N5 METHYLPYRIMIDINE 4,5 DIAMINE; 6 (2 FURYL) N4 (4 METHOXYBENZYL)PYRIMIDINE 4,5 DIAMINE; 6 CHLORO N (4 METHOXYBENZYL) 5 NITROPYRIMIDINE 4 AMINE; 6 CHLORO N (4 METHOXYBENZYL) N METHYL 5 NITROPYRIMIDINE 4 AMINE; 6 CHLORO N (4 METHOXYBENZYL) N METHYLPYRIMIDINE 4 AMINE; 6 CHLORO N (4 METHOXYBENZYL)PYRIMIDINE 4 AMINE; 6 CHLORO N4 (4 METHOXYBENZYL) N4 METHYLPYRIMIDINE 4,5 DIAMINE; 6 CHLORO N4 (4 METHOXYBENZYL)PYRIMIDINE 4,5 DIAMINE; ANTIINFECTIVE AGENT; N [4 CHLORO 6 (4 METHOXYBENZYLOXY)PYRIMIDIN 5 YL]FORMAMIDE; N {4 CHLORO 6 [(4 METHOXYBENZYL)(METHYL)AMINO]PYRIMIDIN 5 YL}FORMAMIDE; N5 ETHYL 6 (2 FURYL) N4 (4 METHOXYBENZYL)PYRIMIDINE 4,5 DIAMINE; N5,N5 DIMETHYL 6 (2 FURYL) N4 (4 METHOXYBENZYL)PYRIMIDINE 4,5 DIAMINE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BIOLOGICAL ACTIVITY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MAMMAL CELL; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

ANTI-BACTERIAL AGENTS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PURINES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA; MYCOBACTERIUM TUBERCULOSIS;

EID: 77953130147     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.04.035     Document Type: Article

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