Synthesis, structure, and antimycobacterial activity of 6-[1(3H)-isobenzofuranylidenemethyl]purines and analogs

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 18, 2009, Pages 6512-6516

  Brændvang, Morten ^a   Bakken, Vebjørn ^a   Gundersen, Lise Lotte ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

Ab initio calculations; Antimycobacterials; Cross couplings; Purines; X ray

Indexed keywords

2 CHLORO 6 (FURAN 2 YLMETHYL) 9 (4 METHOXYPHENYLMETHYL) 9H PURINE; 6 [1(3H) ISOBENZOFURANYLIDENEMETHYL]PURINE DERIVATIVE; ANTIMYCOBACTERIAL AGENT; PURINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; TUBERCULOSIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTITUBERCULAR AGENTS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CRYSTALLOGRAPHY, X-RAY; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PURINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBERCULOSIS; VERO CELLS;

MAMMALIA; MYCOBACTERIUM TUBERCULOSIS;

EID: 69249087377     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.08.012     Document Type: Article

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