Synthesis, biological activity, and SAR of antimycobacterial 9-aryl-, 9-arylsulfonyl-, and 9-benzyl-6-(2-furyl)purines

Journal of Medicinal Chemistry

Volumn 48, Issue 7, 2005, Pages 2710-2723

  Bakkestuen, Anne Kristin ^a   Gundersen, Lise Lotte ^a   Utenova, Bibigul T ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 6 (2 FURYL) 9 (4 METHOXYPHENYLMETHYL) 9H PURINE; 9 BENZYL 6 (2 FURYL)PURINE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; ARYLATION; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ELECTRON TRANSPORT; INHIBITION KINETICS; MAMMAL CELL; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STILLE REACTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTITUBERCULAR AGENTS; CERCOPITHECUS AETHIOPS; FURANS; MACROPHAGES; MICE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM AVIUM COMPLEX; MYCOBACTERIUM TUBERCULOSIS; PURINES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES; VERO CELLS;

EID: 17144376741     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0408924     Document Type: Article

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