-
1
-
-
56349158387
-
Type 2 diabetes: New genes, new understanding
-
Prokopenko I, McCarthy MI, Lindgren CM. Type 2 diabetes: new genes, new understanding. Trends Genet. 2008;24(12):613-21.
-
(2008)
Trends Genet
, vol.24
, Issue.12
, pp. 613-621
-
-
Prokopenko, I.1
McCarthy, M.I.2
Lindgren, C.M.3
-
2
-
-
57349103144
-
Clinical review: The genetics of type 2 diabetes: A realistic appraisal in 2008
-
Florez JC. Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008. J Clin Endocrinol Metab. 2008;93(12):4633-42.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, Issue.12
, pp. 4633-4642
-
-
Florez, J.C.1
-
3
-
-
44749085712
-
Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: Where are the insulin resistance genes?
-
Florez JC. Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes? Diabetologia. 2008;51(7):1100-10.
-
(2008)
Diabetologia
, vol.51
, Issue.7
, pp. 1100-1110
-
-
Florez, J.C.1
-
4
-
-
0026659006
-
Sulfonylureas in NIDDM
-
Groop LC. Sulfonylureas in NIDDM. Diabetes Care. 1992;15(6):737-54.
-
(1992)
Diabetes Care
, vol.15
, Issue.6
, pp. 737-754
-
-
Groop, L.C.1
-
5
-
-
60449089649
-
Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
American Diabetes Association, European Association for the Study of Diabetes
-
Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B, American Diabetes Association, European Association for the Study of Diabetes. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2009;32(1):193-203.
-
(2009)
Diabetes Care
, vol.32
, Issue.1
, pp. 193-203
-
-
Nathan, D.M.1
Buse, J.B.2
Davidson, M.B.3
Ferrannini, E.4
Holman, R.R.5
Sherwin, R.6
Zinman, B.7
-
6
-
-
56749101779
-
Genotype score in addition to common risk factors for prediction of type 2 diabetes
-
Meigs JB, Shrader P, Sullivan LM, McAteer JB, Fox CS, Dupuis J, Manning AK, Florez JC, Wilson PW, D'Agostino RB Sr, Cupples LA. Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med. 2008;359(21):2208-19.
-
(2008)
N Engl J Med
, vol.359
, Issue.21
, pp. 2208-2219
-
-
Meigs, J.B.1
Shrader, P.2
Sullivan, L.M.3
McAteer, J.B.4
Fox, C.S.5
Dupuis, J.6
Manning, A.K.7
Florez, J.C.8
Wilson, P.W.9
D'Agostino Sr., R.B.10
Cupples, L.A.11
-
7
-
-
34249654186
-
Prediction of incident diabetes mellitus in middle-aged adults: The framingham offspring study
-
DOI 10.1001/archinte.167.10.1068
-
Wilson PW, Meigs JB, Sullivan L, Fox CS, Nathan DM, D'Agostino RB Sr. Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study. Arch Intern Med. 2007;167(10):1068-74. (Pubitemid 46835795)
-
(2007)
Archives of Internal Medicine
, vol.167
, Issue.10
, pp. 1068-1074
-
-
Wilson, P.W.F.1
Meigs, J.B.2
Sullivan, L.3
Fox, C.S.4
Nathan, D.M.5
D'Agostino Sr., R.B.6
-
8
-
-
55649105963
-
Clinical risk factors, DNA variants, and the development of type 2 diabetes
-
Lyssenko V, Jonsson A, Almgren P, Pulizzi N, Isomaa B, Tuomi T, Berglund G, Altshuler D, Nilsson P, Groop L. Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med. 2008;359(21):2220-32.
-
(2008)
N Engl J Med
, vol.359
, Issue.21
, pp. 2220-2232
-
-
Lyssenko, V.1
Jonsson, A.2
Almgren, P.3
Pulizzi, N.4
Isomaa, B.5
Tuomi, T.6
Berglund, G.7
Altshuler, D.8
Nilsson, P.9
Groop, L.10
-
9
-
-
56349096931
-
Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk
-
UK Type 2 Diabetes Genetics Consortium, Palmer CN, Morris AD, Zeggini E, Hattersley AT, McCarthy MI, Frayling TM, Weedon MN
-
Lango H, UK Type 2 Diabetes Genetics Consortium, Palmer CN, Morris AD, Zeggini E, Hattersley AT, McCarthy MI, Frayling TM, Weedon MN. Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. Diabetes. 2008;57(11):3129-35.
-
(2008)
Diabetes
, vol.57
, Issue.11
, pp. 3129-3135
-
-
Lango, H.1
-
10
-
-
58149333712
-
Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: A population-based study
-
van Hoek M, Dehghan A, Witteman JC, van Duijn CM, Uitterlinden AG, Oostra BA, Hofman A, Sijbrands EJ, Janssens AC. Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study. Diabetes. 2008;57(11):3122-8.
-
(2008)
Diabetes
, vol.57
, Issue.11
, pp. 3122-3128
-
-
Van Hoek, M.1
Dehghan, A.2
Witteman, J.C.3
Van Duijn, C.M.4
Uitterlinden, A.G.5
Oostra, B.A.6
Hofman, A.7
Sijbrands, E.J.8
Janssens, A.C.9
-
11
-
-
0030935652
-
Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance: The Da Qing IGT and diabetes study
-
Pan XR, Li GW, Hu YH, Wang JX, Yang WY, An ZX, Hu ZX, Lin J, Xiao JZ, Cao HB, Liu PA, Jiang XG, Jiang YY, Wang JP, Zheng H, Zhang H, Bennett PH, Howard BV. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care. 1997;20(4):537-44. (Pubitemid 27143412)
-
(1997)
Diabetes Care
, vol.20
, Issue.4
, pp. 537-544
-
-
Pan, X.-R.1
Li, G.-W.2
Hu, Y.-H.3
Wang, J.-X.4
Yang, W.-Y.5
An, Z.-X.6
Hu, Z.-X.7
Lin, J.8
Xiao, J.-Z.9
Cao, H.-B.10
Liu, P.-A.11
Jiang, X.-G.12
Jiang, Y.-Y.13
Wang, J.-P.14
Zheng, H.15
Zhang, H.16
Bennett, P.H.17
Howard, B.V.18
-
12
-
-
0035799806
-
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
-
Finnish Diabetes Prevention Study Group
-
Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Rastas M, Salminen V, Uusitupa M, Finnish Diabetes Prevention Study Group. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med. 2001;344(18):1343-50.
-
(2001)
N Engl J Med
, vol.344
, Issue.18
, pp. 1343-1350
-
-
Tuomilehto, J.1
Lindström, J.2
Eriksson, J.G.3
Valle, T.T.4
Hämäläinen, H.5
Ilanne-Parikka, P.6
Keinänen-Kiukaanniemi, S.7
Laakso, M.8
Louheranta, A.9
Rastas, M.10
Salminen, V.11
Uusitupa, M.12
-
13
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
DOI 10.1056/NEJMoa012512
-
Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM, Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346(6):393-403. (Pubitemid 34437694)
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.6
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
Nathan, D.M.7
-
14
-
-
31844452061
-
The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1)
-
DOI 10.1007/s00125-005-0097-z
-
Ramachandran A, Snehalatha C, Mary S, Mukesh B, Bhaskar AD, Vijay V, Indian Diabetes Prevention Programme. The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1). Diabetologia. 2006;49(2):289-97. (Pubitemid 43185397)
-
(2006)
Diabetologia
, vol.49
, Issue.2
, pp. 289-297
-
-
Ramachandran, A.1
Snehalatha, C.2
Mary, S.3
Mukesh, B.4
Bhaskar, A.D.5
Vijay, V.6
-
15
-
-
0037097039
-
Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomised trial
-
DOI 10.1016/S0140-6736(02)08905-5
-
Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, Laakso M, STOP-NIDDM Trail Research Group. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet. 2002;359(9323):2072-7. (Pubitemid 34680970)
-
(2002)
Lancet
, vol.359
, Issue.9323
, pp. 2072-2077
-
-
Chiasson, J.-L.1
Josse, R.G.2
Gomis, R.3
Hanefeld, M.4
Karasik, A.5
Laakso, M.6
-
16
-
-
33748748206
-
Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: A randomised controlled trial
-
DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone Medication) Trial Investigators
-
DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone Medication) Trial Investigators, Gerstein HC, Yusuf S, Bosch J, Pogue J, Sheridan P, Dinccag N, Hanefeld M, Hoogwerf B, Laakso M, Mohan V, Shaw J, Zinman B, Holman RR. Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. Lancet. 2006;368(9541):1096-105.
-
(2006)
Lancet
, vol.368
, Issue.9541
, pp. 1096-1105
-
-
Gerstein, H.C.1
Yusuf, S.2
Bosch, J.3
Pogue, J.4
Sheridan, P.5
Dinccag, N.6
Hanefeld, M.7
Hoogwerf, B.8
Laakso, M.9
Mohan, V.10
Shaw, J.11
Zinman, B.12
Holman, R.R.13
-
17
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet. 2006;38(3):320-3.
-
(2006)
Nat Genet
, vol.38
, Issue.3
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
Helgason, A.7
Stefansson, H.8
Emilsson, V.9
Helgadottir, A.10
Styrkarsdottir, U.11
Magnusson, K.P.12
Walters, G.B.13
Palsdottir, E.14
Jonsdottir, T.15
Gudmundsdottir, T.16
Gylfason, A.17
Saemundsdottir, J.18
Wilensky, R.L.19
Reilly, M.P.20
Rader, D.J.21
Bagger, Y.22
Christiansen, C.23
Gudnason, V.24
Sigurdsson, G.25
Thorsteinsdottir, U.26
Gulcher, J.R.27
Kong, A.28
Stefansson, K.29
more..
-
19
-
-
33746075560
-
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program
-
DOI 10.1056/NEJMoa062418
-
Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, Knowler WC, Nathan DM, Altshuler D, Diabetes Prevention Program Research Group. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med. 2006;355(3):241-50. (Pubitemid 44079339)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.3
, pp. 241-250
-
-
Florez, J.C.1
Jablonski, K.A.2
Bayley, N.3
Pollin, T.I.4
De Bakker, P.I.W.5
Shuldiner, A.R.6
Knowler, W.C.7
Nathan, D.M.8
Altshuler, D.9
-
20
-
-
34247855851
-
Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion
-
DOI 10.1007/s00125-007-0656-6
-
Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M. Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion. Diabetologia. 2007;50(6):1192-200. (Pubitemid 46701561)
-
(2007)
Diabetologia
, vol.50
, Issue.6
, pp. 1192-1200
-
-
Wang, J.1
Kuusisto, J.2
Vanttinen, M.3
Kuulasmaa, T.4
Lindstrom, J.5
Tuomilehto, J.6
Uusitupa, M.7
Laakso, M.8
-
21
-
-
59749097689
-
The association of ENPP1 K121Q with diabetes incidence is abolished by lifestyle modification in the Diabetes Prevention Program
-
Diabetes Prevention Program Research Group.
-
Moore AF, Jablonski KA, Mason CC, McAteer JB, Arakaki RF, Goldstein BJ, Kahn SE, Kitabchi AE, Hanson RL, Knowler WC, Florez JC, Diabetes Prevention Program Research Group. The association of ENPP1 K121Q with diabetes incidence is abolished by lifestyle modification in the Diabetes Prevention Program. J Clin Endocrinol Metab. 2009;94(2):449-55.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, Issue.2
, pp. 449-455
-
-
Moore, A.F.1
Jablonski, K.A.2
Mason, C.C.3
McAteer, J.B.4
Arakaki, R.F.5
Goldstein, B.J.6
Kahn, S.E.7
Kitabchi, A.E.8
Hanson, R.L.9
Knowler, W.C.10
Florez, J.C.11
-
22
-
-
42449116149
-
The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: Evidence from an updated meta-analysis in 42,042 subjects
-
ENPP1 Consortium
-
McAteer JB, Prudente S, Bacci S, Lyon HN, Hirschhorn JN, Trischitta V, Florez JC, ENPP1 Consortium. The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: evidence from an updated meta-analysis in 42,042 subjects. Diabetes. 2008;57(4):1125-30.
-
(2008)
Diabetes
, vol.57
, Issue.4
, pp. 1125-1130
-
-
McAteer, J.B.1
Prudente, S.2
Bacci, S.3
Lyon, H.N.4
Hirschhorn, J.N.5
Trischitta, V.6
Florez, J.C.7
-
23
-
-
48249098981
-
Haplotype structure of the ENPP1 gene and nominal association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study
-
Stolerman ES, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB, Florez JC. Haplotype structure of the ENPP1 gene and nominal association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study. Diabetes. 2008;57(7):1971-7.
-
(2008)
Diabetes
, vol.57
, Issue.7
, pp. 1971-1977
-
-
Stolerman, E.S.1
Manning, A.K.2
McAteer, J.B.3
Dupuis, J.4
Fox, C.S.5
Cupples, L.A.6
Meigs, J.B.7
Florez, J.C.8
-
24
-
-
58149354288
-
Role of the ENPP1 K121Q polymorphism in glucose homeostasis
-
Baratta R, Rossetti P, Prudente S, Barbetti F, Sudano D, Nigro A, Farina MG, Pellegrini F, Trischitta V, Frittitta L. Role of the ENPP1 K121Q polymorphism in glucose homeostasis. Diabetes. 2008;57(12):3360-4.
-
(2008)
Diabetes
, vol.57
, Issue.12
, pp. 3360-3364
-
-
Baratta, R.1
Rossetti, P.2
Prudente, S.3
Barbetti, F.4
Sudano, D.5
Nigro, A.6
Farina, M.G.7
Pellegrini, F.8
Trischitta, V.9
Frittitta, L.10
-
25
-
-
55649107932
-
The search for putative unifying genetic factors for components of the metabolic syndrome
-
Sjögren M, Lyssenko V, Jonsson A, Berglund G, Nilsson P, Groop L, Orho-Melander M. The search for putative unifying genetic factors for components of the metabolic syndrome. Diabetologia. 2008;51(12):2242-51.
-
(2008)
Diabetologia
, vol.51
, Issue.12
, pp. 2242-2251
-
-
Sjögren, M.1
Lyssenko, V.2
Jonsson, A.3
Berglund, G.4
Nilsson, P.5
Groop, L.6
Orho-Melander, M.7
-
26
-
-
0033847575
-
Sensitivity to sulphonylureas in patients with hepatocyte nuclear factor-1alpha gene mutations: Evidence for pharmacogenetics in diabetes
-
DOI 10.1046/j.1464-5491.2000.00305.x
-
Pearson ER, Liddell WG, Shepherd M, Corrall RJ, Hattersley AT. Sensitivity to sulphonylureas in patients with hepatocyte nuclear factor-1a gene mutations: evidence for pharmacogenetics in diabetes. Diabet Med. 2000;17(7):543-5. (Pubitemid 30660158)
-
(2000)
Diabetic Medicine
, vol.17
, Issue.7
, pp. 543-545
-
-
Pearson, E.R.1
Liddell, W.G.2
Shepherd, M.3
Corrall, R.J.4
Hattersley, A.T.5
-
27
-
-
33746686369
-
Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations
-
Neonatal Diabetes International Collaborative Group
-
Pearson ER, Flechtner I, Njølstad PR, Malecki MT, Flanagan SE, Larkin B, Ashcroft FM, Klimes I, Codner E, Iotova V, Slingerland AS, Shield J, Robert JJ, Holst JJ, Clark PM, Ellard S, Søvik O, Polak M, Hattersley AT, Neonatal Diabetes International Collaborative Group. Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations. N Engl J Med. 2006;355(5):467-77.
-
(2006)
N Engl J Med
, vol.355
, Issue.5
, pp. 467-477
-
-
Pearson, E.R.1
Flechtner, I.2
Njølstad, P.R.3
Malecki, M.T.4
Flanagan, S.E.5
Larkin, B.6
Ashcroft, F.M.7
Klimes, I.8
Codner, E.9
Iotova, V.10
Slingerland, A.S.11
Shield, J.12
Robert, J.J.13
Holst, J.J.14
Clark, P.M.15
Ellard, S.16
Søvik, O.17
Polak, M.18
Hattersley, A.T.19
-
28
-
-
33746778878
-
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus
-
Babenko AP, Polak M, Cavé H, Busiah K, Czernichow P, Scharfmann R, Bryan J, Aguilar-Bryan L, Vaxillaire M, Froguel P. Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. N Engl J Med. 2006;355(5):456-66.
-
(2006)
N Engl J Med
, vol.355
, Issue.5
, pp. 456-466
-
-
Babenko, A.P.1
Polak, M.2
Cavé, H.3
Busiah, K.4
Czernichow, P.5
Scharfmann, R.6
Bryan, J.7
Aguilar-Bryan, L.8
Vaxillaire, M.9
Froguel, P.10
-
29
-
-
0033624575
-
The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, Nemesh J, Lane CR, Schaffner SF, Bolk S, Brewer C, Tuomi T, Gaudet D, Hudson TJ, Daly M, Groop L, Lander ES. The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet. 2000;26(1):76-80.
-
(2000)
Nat Genet
, vol.26
, Issue.1
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.C.5
Nemesh, J.6
Lane, C.R.7
Schaffner, S.F.8
Bolk, S.9
Brewer, C.10
Tuomi, T.11
Gaudet, D.12
Hudson, T.J.13
Daly, M.14
Groop, L.15
Lander, E.S.16
-
30
-
-
0037317981
-
ATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
-
DOI 10.2337/diabetes.52.2.568
-
Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, Hitman G, Walker M, Levy JC, Sampson M, Halford S, McCarthy MI, Hattersley AT, Frayling TM. Large-scale association studies of variants in genes encoding the pancreatic β-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes. 2003;52(2):568-72. (Pubitemid 36173218)
-
(2003)
Diabetes
, vol.52
, Issue.2
, pp. 568-572
-
-
Gloyn, A.L.1
Weedon, M.N.2
Owen, K.R.3
Turner, M.J.4
Knight, B.A.5
Hitman, G.6
Walker, M.7
Levy, J.C.8
Sampson, M.9
Halford, S.10
McCarthy, M.I.11
Hattersley, A.T.12
Frayling, T.M.13
-
31
-
-
18344417084
-
Analysis of the relationship between the Pro12Ala variant in the PPARγ-gene and the response rate to therapy with pioglitazone in patients with type 2 diabetes
-
Blüher M, Lübben G, Paschke R. Analysis of the relationship between the Pro12Ala variant in the PPARγ-gene and the response rate to therapy with pioglitazone in patients with type 2 diabetes. Diabetes Care. 2003;26(3):825-31.
-
(2003)
Diabetes Care
, vol.26
, Issue.3
, pp. 825-831
-
-
Blüher, M.1
Lübben, G.2
Paschke, R.3
-
32
-
-
2542443906
-
Changes in insulin sensitivity in response to troglitazone do not differ between subjects with and without the common, functional pro 12Ala peroxisome proliferator-activated receptor-gamma2 gene variant: Results from the troglitazone in prevention of diabetes (TRIPOD) study
-
DOI 10.2337/diacare.27.6.1365
-
Snitker S, Watanabe RM, Ani I, Xiang AH, Marroquin A, Ochoa C, Goico J, Shuldiner AR, Buchanan TA, Troglitazone in Prevention of Diabetes (TRIPOD) study. Changes in insulin sensitivity in response to troglitazone do not differ between subjects with and without the common, functional Pro12Ala peroxisome proliferator-activated receptor-gamma2 gene variant: results from the Troglitazone in Prevention of Diabetes (TRIPOD) study. Diabetes Care. 2004;27(6):1365-8. (Pubitemid 38679984)
-
(2004)
Diabetes Care
, vol.27
, Issue.6
, pp. 1365-1368
-
-
Snitker, S.1
Watanabe, R.M.2
Ani, I.3
Xiang, A.H.4
Marroquin, A.5
Ochoa, C.6
Goico, J.7
Shuldiner, A.R.8
Buchanan, T.A.9
-
33
-
-
34147106645
-
Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone
-
DOI 10.1210/jc.2006-2275
-
Florez JC, Jablonski KA, Sun MW, Bayley N, Kahn SE, Shamoon H, Hamman RF, Knowler WC, Nathan DM, Altshuler D, Diabetes Prevention Program Research Group. Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone. J Clin Endocrinol Metab. 2007;92(4):1502-9. (Pubitemid 46556431)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.4
, pp. 1502-1509
-
-
Florez, J.C.1
Jablonski, K.A.2
Sun, M.W.3
Bayley, N.4
Kahn, S.E.5
Shamoon, H.6
Hamman, R.F.7
Knowler, W.C.8
Nathan, D.M.9
Altshuler, D.10
-
34
-
-
23444457610
-
Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor γ2 gene on rosiglitazone response in type 2 diabetes
-
Kang ES, Park SY, Kim HJ, Kim CS, Ahn CW, Cha BS, Lim SK, Nam CM, Lee HC. Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor γ2 gene on rosiglitazone response in type 2 diabetes. Clin Pharmacol Ther. 2005;78(2):202-8.
-
(2005)
Clin Pharmacol Ther
, vol.78
, Issue.2
, pp. 202-208
-
-
Kang, E.S.1
Park, S.Y.2
Kim, H.J.3
Kim, C.S.4
Ahn, C.W.5
Cha, B.S.6
Lim, S.K.7
Nam, C.M.8
Lee, H.C.9
-
35
-
-
33644669582
-
Sequence variation in PPARG may underlie differential response to troglitazone
-
Wolford JK, Yeatts KA, Dhanjal SK, Black MH, Xiang AH, Buchanan TA, Watanabe RM. Sequence variation in PPARG may underlie differential response to troglitazone. Diabetes. 2005;54(11):3319-25.
-
(2005)
Diabetes
, vol.54
, Issue.11
, pp. 3319-3325
-
-
Wolford, J.K.1
Yeatts, K.A.2
Dhanjal, S.K.3
Black, M.H.4
Xiang, A.H.5
Buchanan, T.A.6
Watanabe, R.M.7
-
36
-
-
0035043009
-
Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53)
-
DOI 10.1046/j.1464-5491.2001.00449.x
-
Gloyn AL, Hashim Y, Ashcroft SJ, Ashfield R, Wiltshire S, Turner RC, UK Prospective Diabetes Study (UKPDS 53). Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with type 2 diabetes mellitus (UKPDS 53). Diabet Med. 2001;18(3):206-12. (Pubitemid 32397858)
-
(2001)
Diabetic Medicine
, vol.18
, Issue.3
, pp. 206-212
-
-
Gloyn, A.L.1
Hashim, Y.2
Ashcroft, S.J.H.3
Ashfield, R.4
Wiltshire, S.5
Turner, R.C.6
-
37
-
-
33744965950
-
The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5′-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes
-
DOI 10.1210/jc.2005-2323
-
Sesti G, Laratta E, Cardellini M, Andreozzi F, Del Guerra S, Irace C, Gnasso A, Grupillo M, Lauro R, Hribal ML, Perticone F, Marchetti P. The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5′-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes. J Clin Endocrinol Metab. 2006;91(6):2334-9. (Pubitemid 43855025)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.6
, pp. 2334-2339
-
-
Sesti, G.1
Laratta, E.2
Cardellini, M.3
Andreozzi, F.4
Del, G.S.5
Irace, C.6
Gnasso, A.7
Grupillo, M.8
Lauro, R.9
Hribal, M.L.10
Perticone, F.11
Marchetti, P.12
-
38
-
-
56149106823
-
Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients
-
Feng Y, Mao G, Ren X, Xing H, Tang G, Li Q, Li X, Sun L, Yang J, Ma W, Wang X, Xu X. Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients. Diabetes Care. 2008;31(10):1939-44.
-
(2008)
Diabetes Care
, vol.31
, Issue.10
, pp. 1939-1944
-
-
Feng, Y.1
Mao, G.2
Ren, X.3
Xing, H.4
Tang, G.5
Li, Q.6
Li, X.7
Sun, L.8
Yang, J.9
Ma, W.10
Wang, X.11
Xu, X.12
-
39
-
-
2342561802
-
Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region
-
DOI 10.2337/diabetes.53.5.1360
-
Florez JC, Burtt N, de Bakker PI, Almgren P, Tuomi T, Holmkvist J, Gaudet D, Hudson TJ, Schaffner SF, Daly MJ, Hirschhorn JN, Groop L, Altshuler D. Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region. Diabetes. 2004;53(5):1360-8. (Pubitemid 38569024)
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1360-1368
-
-
Florez, J.C.1
Burtt, N.2
De Bakker, P.I.W.3
Almgren, P.4
Tuomi, T.5
Holmkvist, J.6
Gaudet, D.7
Hudson, T.J.8
Schaffner, S.F.9
Daly, M.J.10
Hirschhorn, J.N.11
Groop, L.12
Altshuler, D.13
-
40
-
-
33750892139
-
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
-
DOI 10.2337/db06-0381
-
Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, Sjögren M, Florez JC, Almgren P, Isomaa B, Orho-Melander M, Lindblad U, Daly MJ, Tuomi T, Hirschhorn JN, Ardlie KG, Groop LC, Altshuler D. Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals. Diabetes. 2006;55(10):2890-5. (Pubitemid 44923692)
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2890-2895
-
-
Saxena, R.1
Gianniny, L.2
Burtt, N.P.3
Lyssenko, V.4
Giuducci, C.5
Sjogren, M.6
Florez, J.C.7
Almgren, P.8
Isomaa, B.9
Orho-Melander, M.10
Lindblad, U.11
Daly, M.J.12
Tuomi, T.13
Hirschhorn, J.N.14
Ardlie, K.G.15
Groop, L.C.16
Altshuler, D.17
-
41
-
-
34547585382
-
Variation in TCF7L2 influences therapeutic response to sulfonylureas: A GoDARTs study
-
DOI 10.2337/db07-0440
-
Pearson ER, Donnelly LA, Kimber C, Whitley A, Doney AS, McCarthy MI, Hattersley AT, Morris AD, Palmer CN. Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study. Diabetes. 2007;56(8):2178-82. (Pubitemid 47195841)
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 2178-2182
-
-
Pearson, E.R.1
Donnelly, L.A.2
Kimber, C.3
Whitley, A.4
Doney, A.S.F.5
McCarthy, M.I.6
Hattersley, A.T.7
Morris, A.D.8
Palmer, C.N.A.9
-
42
-
-
34248156160
-
Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action
-
DOI 10.1172/JCI30558
-
Shu Y, Sheardown SA, Brown C, Owen RP, Zhang S, Castro RA, Ianculescu AG, Yue L, Lo JC, Burchard EG, Brett CM, Giacomini KM. Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. J Clin Invest. 2007;117(5):1422-31. (Pubitemid 46718430)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.5
, pp. 1422-1431
-
-
Shu, Y.1
Sheardown, S.A.2
Brown, C.3
Owen, R.P.4
Zhang, S.5
Castro, R.A.6
Ianculescu, A.G.7
Yue, L.8
Lo, J.C.9
Burchard, E.G.10
Brett, C.M.11
Giacomini, K.M.12
-
43
-
-
66649121405
-
Reduced function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: A Go-DARTS study
-
Zhou K, Donnelly LA, Kimber CH, Donnan PT, Doney AS, Leese G, Hattersley AT, McCarthy MI, Morris AD, Palmer CN, Pearson ER. Reduced function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: a Go-DARTS study. Diabetes. 2009;58(6):1434-9.
-
(2009)
Diabetes
, vol.58
, Issue.6
, pp. 1434-1439
-
-
Zhou, K.1
Donnelly, L.A.2
Kimber, C.H.3
Donnan, P.T.4
Doney, A.S.5
Leese, G.6
Hattersley, A.T.7
McCarthy, M.I.8
Morris, A.D.9
Palmer, C.N.10
Pearson, E.R.11
-
44
-
-
62749133967
-
Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: A preliminary study
-
Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH. Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study. Diabetes. 2009;58(3):745-9.
-
(2009)
Diabetes
, vol.58
, Issue.3
, pp. 745-749
-
-
Becker, M.L.1
Visser, L.E.2
Van Schaik, R.H.3
Hofman, A.4
Uitterlinden, A.G.5
Stricker, B.H.6
|