-
1
-
-
19344374617
-
An essential, putative MEK kinase of Leishmania major
-
Agron P.G., Reed S.L., Engel J.N. An essential, putative MEK kinase of Leishmania major. Mol. Biochem. Parasitol. 2005, 142:121-125.
-
(2005)
Mol. Biochem. Parasitol.
, vol.142
, pp. 121-125
-
-
Agron, P.G.1
Reed, S.L.2
Engel, J.N.3
-
2
-
-
33749853607
-
A probability-based approach for high-throughput protein phosphorylation analysis and site localization
-
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Nat. Biotechnol. 2006, 24:1285-1292.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1285-1292
-
-
Beausoleil, S.A.1
Villen, J.2
Gerber, S.A.3
Rush, J.4
Gygi, S.P.5
-
3
-
-
0033768154
-
Deletion of the gene for the membrane-bound acid phosphatase of Leishmania mexicana
-
Benzel I., Weise F., Wiese M. Deletion of the gene for the membrane-bound acid phosphatase of Leishmania mexicana. Mol. Biochem. Parasitol. 2000, 111:77-86.
-
(2000)
Mol. Biochem. Parasitol.
, vol.111
, pp. 77-86
-
-
Benzel, I.1
Weise, F.2
Wiese, M.3
-
4
-
-
35148827468
-
Structural and functional characterization of the human protein kinase ASK1
-
Bunkoczi G., Salah E., Filippakopoulos P., Fedorov O., Muller S., Sobott F., Parker S.A., Zhang H., Min W., Turk B.E., Knapp S. Structural and functional characterization of the human protein kinase ASK1. Structure 2007, 15:1215-1226.
-
(2007)
Structure
, vol.15
, pp. 1215-1226
-
-
Bunkoczi, G.1
Salah, E.2
Filippakopoulos, P.3
Fedorov, O.4
Muller, S.5
Sobott, F.6
Parker, S.A.7
Zhang, H.8
Min, W.9
Turk, B.E.10
Knapp, S.11
-
5
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang L., Karin M. Mammalian MAP kinase signalling cascades. Nature 2001, 410:37-40.
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
6
-
-
0027995077
-
PJC20 and pJC40 - two high-copy-number vectors for T7 RNA polymerase-dependent expression of recombinant genes in Escherichia coli
-
Clos J., Brandau S. PJC20 and pJC40 - two high-copy-number vectors for T7 RNA polymerase-dependent expression of recombinant genes in Escherichia coli. Protein Expr. Purif. 1994, 5:133-137.
-
(1994)
Protein Expr. Purif.
, vol.5
, pp. 133-137
-
-
Clos, J.1
Brandau, S.2
-
7
-
-
63749083925
-
Targeting protein kinases for the development of anti-inflammatory drugs
-
Cohen P. Targeting protein kinases for the development of anti-inflammatory drugs. Curr. Opin. Cell Biol. 2009, 21:317-324.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 317-324
-
-
Cohen, P.1
-
8
-
-
0026539931
-
The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product
-
Crews C.M., Alessandrini A., Erikson R.L. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science 1992, 258:478-480.
-
(1992)
Science
, vol.258
, pp. 478-480
-
-
Crews, C.M.1
Alessandrini, A.2
Erikson, R.L.3
-
9
-
-
0028228861
-
Stage-specific regulation of protein phosphorylation in Leishmania major
-
Dell K.R., Engel J.N. Stage-specific regulation of protein phosphorylation in Leishmania major. Mol. Biochem. Parasitol. 1994, 64:283-292.
-
(1994)
Mol. Biochem. Parasitol.
, vol.64
, pp. 283-292
-
-
Dell, K.R.1
Engel, J.N.2
-
10
-
-
22244472295
-
Comparative genomics of trypanosomatid parasitic protozoa
-
El Sayed N.M., Myler P.J., Blandin G., Berriman M., Crabtree J., Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C., Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.N., Wortman J.R., Alsmark U.C., Angiuoli S., Anupama A., Badger J., Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T., Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C., Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L., Shallom J., Silva J.C., Sundaram J., Westenberger S., White O., Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N. Comparative genomics of trypanosomatid parasitic protozoa. Science 2005, 309:404-409.
-
(2005)
Science
, vol.309
, pp. 404-409
-
-
El Sayed, N.M.1
Myler, P.J.2
Blandin, G.3
Berriman, M.4
Crabtree, J.5
Aggarwal, G.6
Caler, E.7
Renauld, H.8
Worthey, E.A.9
Hertz-Fowler, C.10
Ghedin, E.11
Peacock, C.12
Bartholomeu, D.C.13
Haas, B.J.14
Tran, A.N.15
Wortman, J.R.16
Alsmark, U.C.17
Angiuoli, S.18
Anupama, A.19
Badger, J.20
Bringaud, F.21
Cadag, E.22
Carlton, J.M.23
Cerqueira, G.C.24
Creasy, T.25
Delcher, A.L.26
Djikeng, A.27
Embley, T.M.28
Hauser, C.29
Ivens, A.C.30
Kummerfeld, S.K.31
Pereira-Leal, J.B.32
Nilsson, D.33
Peterson, J.34
Salzberg, S.L.35
Shallom, J.36
Silva, J.C.37
Sundaram, J.38
Westenberger, S.39
White, O.40
Melville, S.E.41
Donelson, J.E.42
Andersson, B.43
Stuart, K.D.44
Hall, N.45
more..
-
11
-
-
33745262164
-
Interacting protein kinases involved in the regulation of flagellar length
-
Erdmann M., Scholz A., Melzer I.M., Schmetz C., Wiese M. Interacting protein kinases involved in the regulation of flagellar length. Mol. Biol. Cell. 2006, 17:2035-2045.
-
(2006)
Mol. Biol. Cell.
, vol.17
, pp. 2035-2045
-
-
Erdmann, M.1
Scholz, A.2
Melzer, I.M.3
Schmetz, C.4
Wiese, M.5
-
12
-
-
0032102902
-
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution
-
Eyers P.A., Craxton M., Morrice N., Cohen P., Goedert M. Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution. Chem. Biol. 1998, 5:321-328.
-
(1998)
Chem. Biol.
, vol.5
, pp. 321-328
-
-
Eyers, P.A.1
Craxton, M.2
Morrice, N.3
Cohen, P.4
Goedert, M.5
-
13
-
-
0025924328
-
Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase
-
Featherstone C., Russell P. Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase. Nature 1991, 349:808-811.
-
(1991)
Nature
, vol.349
, pp. 808-811
-
-
Featherstone, C.1
Russell, P.2
-
14
-
-
26244444772
-
Mitogen-activated protein kinase (MAPK)-docking sites in MAPK kinases function as tethers that are crucial for MAPK regulation in vivo
-
Grewal S., Molina D.M., Bardwell L. Mitogen-activated protein kinase (MAPK)-docking sites in MAPK kinases function as tethers that are crucial for MAPK regulation in vivo. Cell Signal. 2006, 18:123-134.
-
(2006)
Cell Signal.
, vol.18
, pp. 123-134
-
-
Grewal, S.1
Molina, D.M.2
Bardwell, L.3
-
15
-
-
0025977037
-
Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
-
Guan K.L., Dixon J.E. Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem. 1991, 192:262-267.
-
(1991)
Anal. Biochem.
, vol.192
, pp. 262-267
-
-
Guan, K.L.1
Dixon, J.E.2
-
16
-
-
0029020282
-
Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification
-
Hanks S.K., Hunter T. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 1995, 9:576-596.
-
(1995)
FASEB J.
, vol.9
, pp. 576-596
-
-
Hanks, S.K.1
Hunter, T.2
-
17
-
-
22244437571
-
The genome of the kinetoplastid parasite, Leishmania major
-
Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G., Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A., Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M., Bianchettin G., Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E., Ciarloni L., Clayton C., Coulson R.M., Cronin A., Cruz A.K., Davies R.M., De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N., Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A., Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S., Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M., Masuy D., Matthews K., Michaeli S., Mottram J.C., Muller-Auer S., Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M., Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E., Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C., Rutter S., Saunders D., Schafer M., Schein J., Schwartz D.C., Seeger K., Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V., Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J., Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D., Barrell B., Myler P.J. The genome of the kinetoplastid parasite, Leishmania major. Science 2005, 309:436-442.
-
(2005)
Science
, vol.309
, pp. 436-442
-
-
Ivens, A.C.1
Peacock, C.S.2
Worthey, E.A.3
Murphy, L.4
Aggarwal, G.5
Berriman, M.6
Sisk, E.7
Rajandream, M.A.8
Adlem, E.9
Aert, R.10
Anupama, A.11
Apostolou, Z.12
Attipoe, P.13
Bason, N.14
Bauser, C.15
Beck, A.16
Beverley, S.M.17
Bianchettin, G.18
Borzym, K.19
Bothe, G.20
Bruschi, C.V.21
Collins, M.22
Cadag, E.23
Ciarloni, L.24
Clayton, C.25
Coulson, R.M.26
Cronin, A.27
Cruz, A.K.28
Davies, R.M.29
De Gaudenzi, J.30
Dobson, D.E.31
Duesterhoeft, A.32
Fazelina, G.33
Fosker, N.34
Frasch, A.C.35
Fraser, A.36
Fuchs, M.37
Gabel, C.38
Goble, A.39
Goffeau, A.40
Harris, D.41
Hertz-Fowler, C.42
Hilbert, H.43
Horn, D.44
Huang, Y.45
Klages, S.46
Knights, A.47
Kube, M.48
Larke, N.49
Litvin, L.50
Lord, A.51
Louie, T.52
Marra, M.53
Masuy, D.54
Matthews, K.55
Michaeli, S.56
Mottram, J.C.57
Muller-Auer, S.58
Munden, H.59
Nelson, S.60
Norbertczak, H.61
Oliver, K.62
O'neil, S.63
Pentony, M.64
Pohl, T.M.65
Price, C.66
Purnelle, B.67
Quail, M.A.68
Rabbinowitsch, E.69
Reinhardt, R.70
Rieger, M.71
Rinta, J.72
Robben, J.73
Robertson, L.74
Ruiz, J.C.75
Rutter, S.76
Saunders, D.77
Schafer, M.78
Schein, J.79
Schwartz, D.C.80
Seeger, K.81
Seyler, A.82
Sharp, S.83
Shin, H.84
Sivam, D.85
Squares, R.86
Squares, S.87
Tosato, V.88
Vogt, C.89
Volckaert, G.90
Wambutt, R.91
Warren, T.92
Wedler, H.93
Woodward, J.94
Zhou, S.95
Zimmermann, W.96
Smith, D.F.97
Blackwell, J.M.98
Stuart, K.D.99
more..
-
18
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
-
Johnson G.L., Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002, 298:1911-1912.
-
(2002)
Science
, vol.298
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
19
-
-
19944401878
-
LmxPK4, a mitogen-activated protein kinase kinase homologue of Leishmania mexicana with a potential role in parasite differentiation
-
Kuhn D., Wiese M. LmxPK4, a mitogen-activated protein kinase kinase homologue of Leishmania mexicana with a potential role in parasite differentiation. Mol. Microbiol. 2005, 56:1169-1182.
-
(2005)
Mol. Microbiol.
, vol.56
, pp. 1169-1182
-
-
Kuhn, D.1
Wiese, M.2
-
20
-
-
36448991500
-
Clustal W and Clustal X version 2.0
-
Larkin M.A., Blackshields G., Brown N.P., Chenna R., McGettigan P.A., McWilliam H., Valentin F., Wallace I.M., Wilm A., Lopez R., Thompson J.D., Gibson T.J., Higgins D.G. Clustal W and Clustal X version 2.0. Bioinformatics 2007, 23:2947-2948.
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Larkin, M.A.1
Blackshields, G.2
Brown, N.P.3
Chenna, R.4
McGettigan, P.A.5
McWilliam, H.6
Valentin, F.7
Wallace, I.M.8
Wilm, A.9
Lopez, R.10
Thompson, J.D.11
Gibson, T.J.12
Higgins, D.G.13
-
21
-
-
53249105444
-
Development of new antileishmanial drugs - current knowledge and future prospects
-
Le Pape P. Development of new antileishmanial drugs - current knowledge and future prospects. J. Enzyme Inhib. Med. Chem. 2008, 23:708-718.
-
(2008)
J. Enzyme Inhib. Med. Chem.
, vol.23
, pp. 708-718
-
-
Le Pape, P.1
-
22
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee J.C., Laydon J.T., McDonnell P.C., Gallagher T.F., Kumar S., Green D., McNulty D., Blumenthal M.J., Heys J.R., Landvatter S.W. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994, 372:739-746.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
23
-
-
0033780929
-
Mitogen-activated protein (MAP) kinase pathways in plants: versatile signaling tools
-
Ligterink W., Hirt H. Mitogen-activated protein (MAP) kinase pathways in plants: versatile signaling tools. Int. Rev. Cytol. 2001, 201:209-275.
-
(2001)
Int. Rev. Cytol.
, vol.201
, pp. 209-275
-
-
Ligterink, W.1
Hirt, H.2
-
24
-
-
0026555495
-
Dual-specificity protein kinases: will any hydroxyl do?
-
Lindberg R.A., Quinn A.M., Hunter T. Dual-specificity protein kinases: will any hydroxyl do?. Trends Biochem. Sci. 1992, 17:114-119.
-
(1992)
Trends Biochem. Sci.
, vol.17
, pp. 114-119
-
-
Lindberg, R.A.1
Quinn, A.M.2
Hunter, T.3
-
25
-
-
74049122035
-
Drug resistance in visceral leishmaniasis
-
Maltezou H.C. Drug resistance in visceral leishmaniasis. J. Biomed. Biotechnol. 2010, 2010:617521.
-
(2010)
J. Biomed. Biotechnol.
, vol.2010
, pp. 617521
-
-
Maltezou, H.C.1
-
26
-
-
4944253500
-
The Arabidopsis thaliana MEK AtMKK6 activates the MAP kinase AtMPK13
-
Melikant B., Giuliani C., Halbmayer-Watzina S., Limmongkon A., Heberle-Bors E., Wilson C. The Arabidopsis thaliana MEK AtMKK6 activates the MAP kinase AtMPK13. FEBS Lett. 2004, 576:5-8.
-
(2004)
FEBS Lett.
, vol.576
, pp. 5-8
-
-
Melikant, B.1
Giuliani, C.2
Halbmayer-Watzina, S.3
Limmongkon, A.4
Heberle-Bors, E.5
Wilson, C.6
-
27
-
-
0033785992
-
Biochemical characterization and localization of the dual specificity kinase CLK1
-
Menegay H.J., Myers M.P., Moeslein F.M., Landreth G.E. Biochemical characterization and localization of the dual specificity kinase CLK1. J. Cell Sci. 2000, 113:3241-3253.
-
(2000)
J. Cell Sci.
, vol.113
, pp. 3241-3253
-
-
Menegay, H.J.1
Myers, M.P.2
Moeslein, F.M.3
Landreth, G.E.4
-
28
-
-
34447623007
-
Over-expression of Leishmania major MAP kinases reveals stage-specific induction of phosphotransferase activity
-
Morales M.A., Renaud O., Faigle W., Shorte S.L., Spath G.F. Over-expression of Leishmania major MAP kinases reveals stage-specific induction of phosphotransferase activity. Int. J. Parasitol. 2007, 37:1187-1199.
-
(2007)
Int. J. Parasitol.
, vol.37
, pp. 1187-1199
-
-
Morales, M.A.1
Renaud, O.2
Faigle, W.3
Shorte, S.L.4
Spath, G.F.5
-
29
-
-
15744380263
-
Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition
-
Ohren J.F., Chen H., Pavlovsky A., Whitehead C., Zhang E., Kuffa P., Yan C., McConnell P., Spessard C., Banotai C., Mueller W.T., Delaney A., Omer C., Sebolt-Leopold J., Dudley D.T., Leung I.K., Flamme C., Warmus J., Kaufman M., Barrett S., Tecle H., Hasemann C.A. Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. Nat. Struct. Mol. Biol. 2004, 11:1192-1197.
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 1192-1197
-
-
Ohren, J.F.1
Chen, H.2
Pavlovsky, A.3
Whitehead, C.4
Zhang, E.5
Kuffa, P.6
Yan, C.7
McConnell, P.8
Spessard, C.9
Banotai, C.10
Mueller, W.T.11
Delaney, A.12
Omer, C.13
Sebolt-Leopold, J.14
Dudley, D.T.15
Leung, I.K.16
Flamme, C.17
Warmus, J.18
Kaufman, M.19
Barrett, S.20
Tecle, H.21
Hasemann, C.A.22
more..
-
30
-
-
33750456519
-
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
-
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 2006, 127:635-648.
-
(2006)
Cell
, vol.127
, pp. 635-648
-
-
Olsen, J.V.1
Blagoev, B.2
Gnad, F.3
Macek, B.4
Kumar, C.5
Mortensen, P.6
Mann, M.7
-
31
-
-
0030203863
-
TreeView: an application to display phylogenetic trees on personal computers
-
Page R.D. TreeView: an application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 1996, 12:357-358.
-
(1996)
Comput. Appl. Biosci.
, vol.12
, pp. 357-358
-
-
Page, R.D.1
-
32
-
-
0028359984
-
Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1)
-
Pages G., Brunet A., L'Allemain G., Pouyssegur J. Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1). EMBO J. 1994, 13:3003-3010.
-
(1994)
EMBO J.
, vol.13
, pp. 3003-3010
-
-
Pages, G.1
Brunet, A.2
L'Allemain, G.3
Pouyssegur, J.4
-
33
-
-
25444512182
-
Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi
-
Parsons M., Worthey E.A., Ward P.N., Mottram J.C. Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi. BMC Genomics 2005, 6:127.
-
(2005)
BMC Genomics
, vol.6
, pp. 127
-
-
Parsons, M.1
Worthey, E.A.2
Ward, P.N.3
Mottram, J.C.4
-
34
-
-
0037317228
-
Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics
-
Rappsilber J., Ishihama Y., Mann M. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. Anal. Chem. 2003, 75:663-670.
-
(2003)
Anal. Chem.
, vol.75
, pp. 663-670
-
-
Rappsilber, J.1
Ishihama, Y.2
Mann, M.3
-
35
-
-
33846205114
-
Molecular diagnosis of leishmaniasis: current status and future applications
-
Reithinger R., Dujardin J.C. Molecular diagnosis of leishmaniasis: current status and future applications. J. Clin. Microbiol. 2007, 45:21-25.
-
(2007)
J. Clin. Microbiol.
, vol.45
, pp. 21-25
-
-
Reithinger, R.1
Dujardin, J.C.2
-
36
-
-
4444244846
-
Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stibogluconate and need for a policy to limit further decline
-
Rijal S., Chappuis F., Singh R., Bovier P.A., Acharya P., Karki B.M., Das M.L., Desjeux P., Loutan L., Koirala S. Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stibogluconate and need for a policy to limit further decline. Trans. R. Soc. Trop. Med. Hyg. 2003, 97:350-354.
-
(2003)
Trans. R. Soc. Trop. Med. Hyg.
, vol.97
, pp. 350-354
-
-
Rijal, S.1
Chappuis, F.2
Singh, R.3
Bovier, P.A.4
Acharya, P.5
Karki, B.M.6
Das, M.L.7
Desjeux, P.8
Loutan, L.9
Koirala, S.10
-
37
-
-
0024394417
-
Staurosporine, K-252 and UCN-01: potent but non-specific inhibitors of protein kinases
-
Ruegg U.T., Burgess G.M. Staurosporine, K-252 and UCN-01: potent but non-specific inhibitors of protein kinases. Trends Pharmacol. Sci. 1989, 10:218-220.
-
(1989)
Trends Pharmacol. Sci.
, vol.10
, pp. 218-220
-
-
Ruegg, U.T.1
Burgess, G.M.2
-
38
-
-
0343569838
-
Expression and subcellular localization of cpn60 protein family members in Leishmania donovani
-
Schluter A., Wiesgigl M., Hoyer C., Fleischer S., Klaholz L., Schmetz C., Clos J. Expression and subcellular localization of cpn60 protein family members in Leishmania donovani. Biochim. Biophys. Acta 2000, 1491:65-74.
-
(2000)
Biochim. Biophys. Acta
, vol.1491
, pp. 65-74
-
-
Schluter, A.1
Wiesgigl, M.2
Hoyer, C.3
Fleischer, S.4
Klaholz, L.5
Schmetz, C.6
Clos, J.7
-
39
-
-
0029927505
-
Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
-
Shevchenko A., Wilm M., Vorm O., Mann M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 1996, 68:850-858.
-
(1996)
Anal. Chem.
, vol.68
, pp. 850-858
-
-
Shevchenko, A.1
Wilm, M.2
Vorm, O.3
Mann, M.4
-
40
-
-
33749338420
-
Development of miltefosine as an oral treatment for leishmaniasis
-
Sindermann H., Engel J. Development of miltefosine as an oral treatment for leishmaniasis. Trans. R. Soc. Trop. Med. Hyg. 2006, 100(Suppl. 1):S17-S20.
-
(2006)
Trans. R. Soc. Trop. Med. Hyg.
, vol.100
, Issue.SUPPL. 1
-
-
Sindermann, H.1
Engel, J.2
-
41
-
-
1042288575
-
Amphotericin B treatment for Indian visceral leishmaniasis: conventional versus lipid formulations
-
Sundar S., Mehta H., Suresh A.V., Singh S.P., Rai M., Murray H.W. Amphotericin B treatment for Indian visceral leishmaniasis: conventional versus lipid formulations. Clin. Infect. Dis. 2004, 38:377-383.
-
(2004)
Clin. Infect. Dis.
, vol.38
, pp. 377-383
-
-
Sundar, S.1
Mehta, H.2
Suresh, A.V.3
Singh, S.P.4
Rai, M.5
Murray, H.W.6
-
42
-
-
0034451615
-
Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic
-
Sundar S., More D.K., Singh M.K., Singh V.P., Sharma S., Makharia A., Kumar P.C., Murray H.W. Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic. Clin. Infect. Dis. 2000, 31:1104-1107.
-
(2000)
Clin. Infect. Dis.
, vol.31
, pp. 1104-1107
-
-
Sundar, S.1
More, D.K.2
Singh, M.K.3
Singh, V.P.4
Sharma, S.5
Makharia, A.6
Kumar, P.C.7
Murray, H.W.8
-
43
-
-
0037400611
-
Molecular recognitions in the MAP kinase cascades
-
Tanoue T., Nishida E. Molecular recognitions in the MAP kinase cascades. Cell Signal. 2003, 15:455-462.
-
(2003)
Cell Signal.
, vol.15
, pp. 455-462
-
-
Tanoue, T.1
Nishida, E.2
-
44
-
-
65349177118
-
The use of titanium dioxide micro-columns to selectively isolate phosphopeptides from proteolytic digests
-
Thingholm T.E., Larsen M.R. The use of titanium dioxide micro-columns to selectively isolate phosphopeptides from proteolytic digests. Methods Mol. Biol. 2009, 527:57-66.
-
(2009)
Methods Mol. Biol.
, vol.527
, pp. 57-66
-
-
Thingholm, T.E.1
Larsen, M.R.2
-
45
-
-
30544449006
-
LmxMPK4, a mitogen-activated protein (MAP) kinase homologue essential for promastigotes and amastigotes of Leishmania mexicana
-
Wang Q., Melzer I.M., Kruse M., Sander-Juelch C., Wiese M. LmxMPK4, a mitogen-activated protein (MAP) kinase homologue essential for promastigotes and amastigotes of Leishmania mexicana. Kinetoplastid. Biol. Dis. 2005, 4:6.
-
(2005)
Kinetoplastid. Biol. Dis.
, vol.4
, pp. 6
-
-
Wang, Q.1
Melzer, I.M.2
Kruse, M.3
Sander-Juelch, C.4
Wiese, M.5
-
46
-
-
0032080107
-
A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host
-
Wiese M. A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host. EMBO J. 1998, 17:2619-2628.
-
(1998)
EMBO J.
, vol.17
, pp. 2619-2628
-
-
Wiese, M.1
-
47
-
-
34447262542
-
Leishmania MAP kinases-familiar proteins in an unusual context
-
Wiese M. Leishmania MAP kinases-familiar proteins in an unusual context. Int. J. Parasitol. 2007, 37:1053-1062.
-
(2007)
Int. J. Parasitol.
, vol.37
, pp. 1053-1062
-
-
Wiese, M.1
-
48
-
-
12644277392
-
The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase
-
Wilson K.P., McCaffrey P.G., Hsiao K., Pazhanisamy S., Galullo V., Bemis G.W., Fitzgibbon M.J., Caron P.R., Murcko M.A., Su M.S. The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase. Chem. Biol. 1997, 4:423-431.
-
(1997)
Chem. Biol.
, vol.4
, pp. 423-431
-
-
Wilson, K.P.1
McCaffrey, P.G.2
Hsiao, K.3
Pazhanisamy, S.4
Galullo, V.5
Bemis, G.W.6
Fitzgibbon, M.J.7
Caron, P.R.8
Murcko, M.A.9
Su, M.S.10
-
49
-
-
0028157664
-
Atomic structure of the MAP kinase ERK2 at 2.3Å resolution
-
Zhang F., Strand A., Robbins D., Cobb M.H., Goldsmith E.J. Atomic structure of the MAP kinase ERK2 at 2.3Å resolution. Nature 1994, 367:704-711.
-
(1994)
Nature
, vol.367
, pp. 704-711
-
-
Zhang, F.1
Strand, A.2
Robbins, D.3
Cobb, M.H.4
Goldsmith, E.J.5
-
50
-
-
4644232397
-
Crystal structure of the TAO2 kinase domain: activation and specificity of a Ste20p MAP3K
-
Zhou T., Raman M., Gao Y., Earnest S., Chen Z., Machius M., Cobb M.H., Goldsmith E.J. Crystal structure of the TAO2 kinase domain: activation and specificity of a Ste20p MAP3K. Structure 2004, 12:1891-1900.
-
(2004)
Structure
, vol.12
, pp. 1891-1900
-
-
Zhou, T.1
Raman, M.2
Gao, Y.3
Earnest, S.4
Chen, Z.5
Machius, M.6
Cobb, M.H.7
Goldsmith, E.J.8
-
51
-
-
0028061958
-
The role of pH and temperature in the development of Leishmania parasites
-
Zilberstein D., Shapira M. The role of pH and temperature in the development of Leishmania parasites. Annu. Rev. Microbiol. 1994, 48:449-470.
-
(1994)
Annu. Rev. Microbiol.
, vol.48
, pp. 449-470
-
-
Zilberstein, D.1
Shapira, M.2
|