Therapeutic uses of drug-carrier systems for imidazole-containing dipeptide compounds that act as pharmacological chaperones and have significant impact on the treatment of chronic diseases associated with increased oxidative stress and the formation of advanced glycation end products

Critical Reviews in Therapeutic Drug Carrier Systems

Volumn 27, Issue 2, 2010, Pages 85-154

  Babizhayev, Mark A ^a,b   Yegorov, Yegor E ^c  

^a Innovative Vision Products Incorporated   (United States)

^b MOSCOW HELMHOLTZ RESEARCH INSTITUTE OF EYE DISEASES   (Russian Federation)

^c ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

Age related cataract; Alpha A crystallin; Carcinine; Chemical and pharmacological chaperones; Cosmetic science; L carnosine; Leucyl histidylhydrazide; N acetylcarnosine; Natural imidazole containing peptidomimetics; Ophthalmic treatment; Photoaging; Skin care

Indexed keywords

ACETYLCYSTEINE; ADVANCED GLYCATION END PRODUCT; ASCORBIC ACID; CARCININE; CARNOSINE; CHAPERONE; CRYSTALLIN; CURCUMIN; DIPEPTIDE DERIVATIVE; DOXYCYCLINE; DRUG CARRIER; EYE DROPS; FREE RADICAL; HYDRAZIDE DERIVATIVE; HYDROPEROXIDE; IMIDAZOLE DERIVATIVE; IRON; LINOLEIC ACID; LIPID PEROXIDASE; LIPID PEROXIDE; LIPOSOME; MEMBRANE LIPID; N ACETYLCARNOSINE; PEPTIDOMIMETIC AGENT; POLAPREZINC; RITONAVIR; SUPEROXIDE DISMUTASE; TRIETHYLAMINE; TRIMETHYLAMINE OXIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AGING; ANTIOXIDANT ACTIVITY; AQUEOUS HUMOR; BASAL CELL CARCINOMA; BLINDNESS; CANCER INCIDENCE; CATARACT; CATARACTOGENESIS; CELL AGING; CELL NUCLEUS; CELL PROTECTION; CELL STRESS; CHRONIC DISEASE; COGNITIVE DEFECT; COLITIS; CUTANEOUS PARAMETERS; DIABETES MELLITUS; DIABETIC PATIENT; DIABETIC RETINOPATHY; DISEASE ASSOCIATION; ENVIRONMENTAL FACTOR; ENVIRONMENTAL STRESS; ENZYME ACTIVITY; EPILEPSY; GAIT DISORDER; GLAUCOMA; HISTOPATHOLOGY; HUMAN; HYPERTRICHOSIS; IN VITRO STUDY; IN VIVO STUDY; LENS; LIPID PEROXIDATION; MELANOMA; MOLECULAR INTERACTION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PHOTOAGING; PHOTOTOXICITY; PORPHYRIA CUTANEA TARDA; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; PROTON NUCLEAR MAGNETIC RESONANCE; RETINA MACULA AGE RELATED DEGENERATION; RETINOPATHY; REVIEW; SKIN CANCER; SKIN CARE; SKIN CELL; SKIN DISEASE; SKIN FUNCTION; SKIN INFLAMMATION; SKIN INJURY; SKIN PHOTOTOXICITY; SKIN PROTECTION; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE; ULTRAVIOLET IRRADIATION; VISUAL IMPAIRMENT; VITREORETINOPATHY;

EID: 77952938755     PISSN: 07434863     EISSN: None     Source Type: Journal    
DOI: 10.1615/CritRevTherDrugCarrierSyst.v27.i2.10     Document Type: Review

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