메뉴 건너뛰기




Volumn 24, Issue 4, 2010, Pages 1279-1284

In vitro effects of antiepileptic drugs on acetylcholinesterase and ectonucleotidase activities in zebrafish (Danio rerio) brain

Author keywords

Acetylcholinesterase; Antiepileptic drugs; Ecto 5' nucleotidase; Nucleoside triphosphate diphosphohydrolase; Zebrafish

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; ECTO 5' NUCLEOTIDASE; GABAPENTIN; HYDROLASE; NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE; PHENYTOIN; UNCLASSIFIED DRUG;

EID: 77952938471     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.03.018     Document Type: Article
Times cited : (33)

References (74)
  • 2
    • 59549102715 scopus 로고    scopus 로고
    • Cortical hyperexcitability and epileptogenesis: understanding the mechanisms of epilepsy - part 1
    • Badawy R.A.B., Harvey A.S., Macdonell R.A.L. Cortical hyperexcitability and epileptogenesis: understanding the mechanisms of epilepsy - part 1. Journal of Clinical Neuroscience 2009, 16:355-365.
    • (2009) Journal of Clinical Neuroscience , vol.16 , pp. 355-365
    • Badawy, R.A.B.1    Harvey, A.S.2    Macdonell, R.A.L.3
  • 3
    • 67349192949 scopus 로고    scopus 로고
    • The descriptive epidemiology of epilepsy: a review
    • Banerjee P.N., Filippi D., Hauser W.A. The descriptive epidemiology of epilepsy: a review. Epilepsy Research 2009, 85(1):31-45.
    • (2009) Epilepsy Research , vol.85 , Issue.1 , pp. 31-45
    • Banerjee, P.N.1    Filippi, D.2    Hauser, W.A.3
  • 4
    • 33947148529 scopus 로고    scopus 로고
    • Emerging epilepsy models: insights from mice, flies, worms and fish
    • Baraban S.C. Emerging epilepsy models: insights from mice, flies, worms and fish. Current Opinion in Neurology 2007, 20(2):164-168.
    • (2007) Current Opinion in Neurology , vol.20 , Issue.2 , pp. 164-168
    • Baraban, S.C.1
  • 5
    • 13844314605 scopus 로고    scopus 로고
    • Pentylenetetrazole induced changes in zebrafish behavior, neural activity and c-fos expression
    • Baraban S.C., Taylor M.R., Castro P.A., Baier H. Pentylenetetrazole induced changes in zebrafish behavior, neural activity and c-fos expression. Neuroscience 2005, 131(3):759-768.
    • (2005) Neuroscience , vol.131 , Issue.3 , pp. 759-768
    • Baraban, S.C.1    Taylor, M.R.2    Castro, P.A.3    Baier, H.4
  • 6
    • 0027438050 scopus 로고
    • Interaction of guanine nucleotides with [3H] kainate and 6-[3H]cyano-7-nitroquinoxaline-2,3-dione binding in goldfish brain
    • Barnes J.M., Murphy P.A., Kirkham D., Henley J. Interaction of guanine nucleotides with [3H] kainate and 6-[3H]cyano-7-nitroquinoxaline-2,3-dione binding in goldfish brain. Journal of Neurochemistry 1993, 61(5):1685-1691.
    • (1993) Journal of Neurochemistry , vol.61 , Issue.5 , pp. 1685-1691
    • Barnes, J.M.1    Murphy, P.A.2    Kirkham, D.3    Henley, J.4
  • 7
    • 70349216340 scopus 로고    scopus 로고
    • Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety
    • Bencan Z., Sledge D., Levin E.D. Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety. Pharmacology, Biochemistry and Behavior 2009, 94(1):75-80.
    • (2009) Pharmacology, Biochemistry and Behavior , vol.94 , Issue.1 , pp. 75-80
    • Bencan, Z.1    Sledge, D.2    Levin, E.D.3
  • 8
    • 34249813382 scopus 로고    scopus 로고
    • Zebrafish offer the potential for a primary screen to identify a wide variety of potential anticonvulsants
    • Berghmans S., Hunt J., Roach A., Goldsmith P. Zebrafish offer the potential for a primary screen to identify a wide variety of potential anticonvulsants. Epilepsy Research 2007, 75:18-28.
    • (2007) Epilepsy Research , vol.75 , pp. 18-28
    • Berghmans, S.1    Hunt, J.2    Roach, A.3    Goldsmith, P.4
  • 9
    • 0025853742 scopus 로고
    • Effects of muscarinic receptor agonists and antagonists on response of non-extensor rats to maximal electroshock
    • Bhattacharya S.K., Sen A.P., Mitra S.K. Effects of muscarinic receptor agonists and antagonists on response of non-extensor rats to maximal electroshock. Indian Journal of Experimental Biology 1991, 29(3):237-240.
    • (1991) Indian Journal of Experimental Biology , vol.29 , Issue.3 , pp. 237-240
    • Bhattacharya, S.K.1    Sen, A.P.2    Mitra, S.K.3
  • 10
    • 74049163222 scopus 로고    scopus 로고
    • Key factors in the discovery and development of new antiepileptic drugs
    • Bialer M., White H.S. Key factors in the discovery and development of new antiepileptic drugs. Nature Reviews. Drug Discovery 2010, 9(1):68-82.
    • (2010) Nature Reviews. Drug Discovery , vol.9 , Issue.1 , pp. 68-82
    • Bialer, M.1    White, H.S.2
  • 11
    • 0035812899 scopus 로고    scopus 로고
    • Memory improving actions of gabapentine in mice: possible involvement of central muscarinic cholinergic mechanism
    • Boccia M.M., Acosta G.B., Baratti C.M. Memory improving actions of gabapentine in mice: possible involvement of central muscarinic cholinergic mechanism. Neuroscience Letters 2001, 311:153-156.
    • (2001) Neuroscience Letters , vol.311 , pp. 153-156
    • Boccia, M.M.1    Acosta, G.B.2    Baratti, C.M.3
  • 12
    • 13544274000 scopus 로고    scopus 로고
    • Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies
    • Boison D. Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies. The Neuroscientist 2005, 11(1):25-36.
    • (2005) The Neuroscientist , vol.11 , Issue.1 , pp. 25-36
    • Boison, D.1
  • 13
    • 38649097860 scopus 로고    scopus 로고
    • Adenosine as a neuromodulator in neurological diseases
    • Boison D. Adenosine as a neuromodulator in neurological diseases. Current Opinion in Pharmacology 2008, 8(1):2-7.
    • (2008) Current Opinion in Pharmacology , vol.8 , Issue.1 , pp. 2-7
    • Boison, D.1
  • 14
    • 0030611565 scopus 로고    scopus 로고
    • N6-2-4-aminophenyl/ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs
    • Borowicz K.K., Kleinrok K., Czuczwar S.J. N6-2-4-aminophenyl/ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs. European Journal of Pharmacology 1997, 372(2-3):125-133.
    • (1997) European Journal of Pharmacology , vol.372 , Issue.2-3 , pp. 125-133
    • Borowicz, K.K.1    Kleinrok, K.2    Czuczwar, S.J.3
  • 15
    • 0036177567 scopus 로고    scopus 로고
    • 2-Chloroadenosine, a preferential agonist of adenosine A1 receptors enhances the anticonvulsant activity of carbamazepine and clonazepam in mice
    • Borowicz K.K., Luszczki J., Czuczwar S.J. 2-Chloroadenosine, a preferential agonist of adenosine A1 receptors enhances the anticonvulsant activity of carbamazepine and clonazepam in mice. European Neuropsychopharmacology 2002, 12:173-179.
    • (2002) European Neuropsychopharmacology , vol.12 , pp. 173-179
    • Borowicz, K.K.1    Luszczki, J.2    Czuczwar, S.J.3
  • 16
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 1976, 72:218-254.
    • (1976) Analytical Biochemistry , vol.72 , pp. 218-254
    • Bradford, M.M.1
  • 19
    • 61849128446 scopus 로고    scopus 로고
    • Evolutionary origins of the purinergic signalling system
    • Burnstock G., Verkhratsky A. Evolutionary origins of the purinergic signalling system. Acta Physiologica 2009, 195:415-447.
    • (2009) Acta Physiologica , vol.195 , pp. 415-447
    • Burnstock, G.1    Verkhratsky, A.2
  • 20
    • 0022549284 scopus 로고
    • A direct colorimetric assay for Ca2+-stimulated ATPase activity
    • Chan K.M., Delfert D., Junger K.D. A direct colorimetric assay for Ca2+-stimulated ATPase activity. Analytical Biochemistry 1986, 157:375-380.
    • (1986) Analytical Biochemistry , vol.157 , pp. 375-380
    • Chan, K.M.1    Delfert, D.2    Junger, K.D.3
  • 22
    • 49749128051 scopus 로고    scopus 로고
    • Inhibition of human NTPDase2 by modification of an intramembrane cysteine by p-chloromercuriphenylsulfonate and oxidative cross-linking of the transmembrane domains
    • Chiang W.C., Knowles A.F. Inhibition of human NTPDase2 by modification of an intramembrane cysteine by p-chloromercuriphenylsulfonate and oxidative cross-linking of the transmembrane domains. Biochemistry 2008, 47(33):8775-8785.
    • (2008) Biochemistry , vol.47 , Issue.33 , pp. 8775-8785
    • Chiang, W.C.1    Knowles, A.F.2
  • 24
    • 34248164936 scopus 로고    scopus 로고
    • Antiepileptic drugs prevent changes induced by pilocarpine model of epilepsy in brain ectonucleotidases
    • Cognato G.P., Bruno A.N., da Silva R.S., Bog M.R., Sarkis J.J.F., Bonan C.D. Antiepileptic drugs prevent changes induced by pilocarpine model of epilepsy in brain ectonucleotidases. Neurochemical Research 2007, 32:1046-1055.
    • (2007) Neurochemical Research , vol.32 , pp. 1046-1055
    • Cognato, G.P.1    Bruno, A.N.2    da Silva, R.S.3    Bog, M.R.4    Sarkis, J.J.F.5    Bonan, C.D.6
  • 25
    • 0028297090 scopus 로고
    • Involvement of M1 muscarinic receptors in the initiation of cholinergically induced epileptic seizures in the rat brain
    • Cruickshank J.W., Brudzynski S.M., McLachlan R.S. Involvement of M1 muscarinic receptors in the initiation of cholinergically induced epileptic seizures in the rat brain. Brain Research 1994, 643:125-129.
    • (1994) Brain Research , vol.643 , pp. 125-129
    • Cruickshank, J.W.1    Brudzynski, S.M.2    McLachlan, R.S.3
  • 26
    • 0035255227 scopus 로고    scopus 로고
    • Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors
    • Cunha R.A. Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors. Neurochemistry International 2001, 38:107-125.
    • (2001) Neurochemistry International , vol.38 , pp. 107-125
    • Cunha, R.A.1
  • 28
    • 0030861492 scopus 로고    scopus 로고
    • Muscarinic induction of synchronous population activity in the entorhinal cortex
    • Dickson C.T., Alonso A. Muscarinic induction of synchronous population activity in the entorhinal cortex. The Journal of Neuroscience 1997, 17:6729-6744.
    • (1997) The Journal of Neuroscience , vol.17 , pp. 6729-6744
    • Dickson, C.T.1    Alonso, A.2
  • 29
    • 0034923094 scopus 로고    scopus 로고
    • The role and regulation of adenosine in the central nervous system
    • Dunwiddie T.V., Masino S.A. The role and regulation of adenosine in the central nervous system. Annual Review of Neuroscience 2001, 24:31-55.
    • (2001) Annual Review of Neuroscience , vol.24 , pp. 31-55
    • Dunwiddie, T.V.1    Masino, S.A.2
  • 31
    • 0035209620 scopus 로고    scopus 로고
    • International union of pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • Fredholm B.B., Ijzerman A.P., Jacobson J.K., Klotz K., Linden J. International union of pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacological Reviews 2001, 53(4):527-552.
    • (2001) Pharmacological Reviews , vol.53 , Issue.4 , pp. 527-552
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, J.K.3    Klotz, K.4    Linden, J.5
  • 33
    • 34848926206 scopus 로고    scopus 로고
    • Cholinergic dysfunction in temporal lobe epilepsy
    • Friedman A., Behrens C.J., Heinemann U. Cholinergic dysfunction in temporal lobe epilepsy. Epilepsia 2007, 48(5):126-130.
    • (2007) Epilepsia , vol.48 , Issue.5 , pp. 126-130
    • Friedman, A.1    Behrens, C.J.2    Heinemann, U.3
  • 34
    • 67349202870 scopus 로고    scopus 로고
    • Zebrafish (Danio rerio) responds to the animated image of a predator: towards the development of an automated aversive task
    • Gerlai R., Fernandes Y., Pereira T. Zebrafish (Danio rerio) responds to the animated image of a predator: towards the development of an automated aversive task. Behavioural Brain Research 2009, 201:318-324.
    • (2009) Behavioural Brain Research , vol.201 , pp. 318-324
    • Gerlai, R.1    Fernandes, Y.2    Pereira, T.3
  • 35
    • 33846081115 scopus 로고    scopus 로고
    • CD39, NTPDase1, is attached to the plasma membrane by two transmembrane domains. Why?
    • Grinthal A., Guidotti G. CD39, NTPDase1, is attached to the plasma membrane by two transmembrane domains. Why?. Purinergic Signalling 2006, 2:391-398.
    • (2006) Purinergic Signalling , vol.2 , pp. 391-398
    • Grinthal, A.1    Guidotti, G.2
  • 36
    • 65549132450 scopus 로고    scopus 로고
    • The aspects and mechanisms of cognitive alterations in epilepsy: the role of antiepileptic medication
    • Hamed S.A. The aspects and mechanisms of cognitive alterations in epilepsy: the role of antiepileptic medication. CNS Neuroscience and Therapeutics 2009, 15:134-156.
    • (2009) CNS Neuroscience and Therapeutics , vol.15 , pp. 134-156
    • Hamed, S.A.1
  • 39
    • 63149158008 scopus 로고    scopus 로고
    • The power of the zebrafish for disease analysis
    • Ingham P.W. The power of the zebrafish for disease analysis. Human Molecular Genetics 2009, 18:107-112.
    • (2009) Human Molecular Genetics , vol.18 , pp. 107-112
    • Ingham, P.W.1
  • 40
    • 38049121040 scopus 로고    scopus 로고
    • DNA damage induced by genotoxicants in zebrafish (Danio rerio) embryos after contact exposure to freeze-dried sediment and sediment extracts from Laguna Lake (The Philippines) as measured by the comet assay
    • Kosmehl T., Hallare A.V., Braunbeck T., Hollert H. DNA damage induced by genotoxicants in zebrafish (Danio rerio) embryos after contact exposure to freeze-dried sediment and sediment extracts from Laguna Lake (The Philippines) as measured by the comet assay. Mutation Research 2008, 650:1-14.
    • (2008) Mutation Research , vol.650 , pp. 1-14
    • Kosmehl, T.1    Hallare, A.V.2    Braunbeck, T.3    Hollert, H.4
  • 41
    • 0028274070 scopus 로고
    • Quantitative evaluation of neuronal loss in the dorsal hippocampus in rats with longterm pilocarpine seizures
    • Liu Z., Nagao T., Desjardins C.G., Gloor P., Avoli M. Quantitative evaluation of neuronal loss in the dorsal hippocampus in rats with longterm pilocarpine seizures. Epilepsy Research 1994, 17:237-247.
    • (1994) Epilepsy Research , vol.17 , pp. 237-247
    • Liu, Z.1    Nagao, T.2    Desjardins, C.G.3    Gloor, P.4    Avoli, M.5
  • 42
    • 0001876282 scopus 로고
    • Carbamazepine clinical use
    • Raven Press, New York, R.H. Levy, R.H. Mattson, B.S. Meldrum (Eds.)
    • Loiseau P., Duche B. Carbamazepine clinical use. Antiepileptic Drugs 1995, 555-566. Raven Press, New York. fourth ed. R.H. Levy, R.H. Mattson, B.S. Meldrum (Eds.).
    • (1995) Antiepileptic Drugs , pp. 555-566
    • Loiseau, P.1    Duche, B.2
  • 43
    • 77952906875 scopus 로고    scopus 로고
    • Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy
    • Luna-Tortós C., Fedrowitz M., Löscher W. Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy. Neuropharmacology 2010, 18:1-14.
    • (2010) Neuropharmacology , vol.18 , pp. 1-14
    • Luna-Tortós, C.1    Fedrowitz, M.2    Löscher, W.3
  • 44
    • 0027143716 scopus 로고
    • Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting
    • Mello L.E., Cavalheiro E.A., Tan A.M., Kupfer W.R., Pretorius J.K., Babb T.L., Finch D.M. Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting. Epilepsia 1993, 34:985-995.
    • (1993) Epilepsia , vol.34 , pp. 985-995
    • Mello, L.E.1    Cavalheiro, E.A.2    Tan, A.M.3    Kupfer, W.R.4    Pretorius, J.K.5    Babb, T.L.6    Finch, D.M.7
  • 46
    • 0029916090 scopus 로고    scopus 로고
    • Epileptiform activity induced by pilocarpine in the rat hippocampal-entorhinal slice preparation
    • Nagao T., Alonso A., Avoli M. Epileptiform activity induced by pilocarpine in the rat hippocampal-entorhinal slice preparation. Neuroscience 1996, 72:399-408.
    • (1996) Neuroscience , vol.72 , pp. 399-408
    • Nagao, T.1    Alonso, A.2    Avoli, M.3
  • 53
    • 33846436678 scopus 로고    scopus 로고
    • The E-NTPDase family of ectonucleotidases: structure function relationships and pathophysiological significance
    • Robson S.C., Sévigny J., Zimmermann H. The E-NTPDase family of ectonucleotidases: structure function relationships and pathophysiological significance. Purinergic Signalling 2006, 2:409-430.
    • (2006) Purinergic Signalling , vol.2 , pp. 409-430
    • Robson, S.C.1    Sévigny, J.2    Zimmermann, H.3
  • 56
  • 60
    • 0035320772 scopus 로고    scopus 로고
    • Acetylcholinesterase: news roles for old actor
    • Soreq H., Seidman S. Acetylcholinesterase: news roles for old actor. Nature Reviews. Neuroscience 2001, 2(4):294-302.
    • (2001) Nature Reviews. Neuroscience , vol.2 , Issue.4 , pp. 294-302
    • Soreq, H.1    Seidman, S.2
  • 62
    • 34047250594 scopus 로고    scopus 로고
    • Ecto-5'-nucleotidase: structure function relationships
    • Sträter N. Ecto-5'-nucleotidase: structure function relationships. Purinergic Signalling 2006, 2:343-350.
    • (2006) Purinergic Signalling , vol.2 , pp. 343-350
    • Sträter, N.1
  • 63
    • 0029125229 scopus 로고
    • Chronic phenytoin induced impairment of learning and memory with associated changes in brain acetylcholine esterase activity and monoamine levels
    • Sudha S., Lakshmanat M.K., Pradhan N. Chronic phenytoin induced impairment of learning and memory with associated changes in brain acetylcholine esterase activity and monoamine levels. Pharmacology Biochemistry and Behavior 1995, 52(1):119-124.
    • (1995) Pharmacology Biochemistry and Behavior , vol.52 , Issue.1 , pp. 119-124
    • Sudha, S.1    Lakshmanat, M.K.2    Pradhan, N.3
  • 66
    • 0024510191 scopus 로고
    • Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy
    • Turski L., Ikonomidou C., Turski W.A., Bortolotto Z.A., Cavalheiro E.A. Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy. Synapse 1989, 3:154-171.
    • (1989) Synapse , vol.3 , pp. 154-171
    • Turski, L.1    Ikonomidou, C.2    Turski, W.A.3    Bortolotto, Z.A.4    Cavalheiro, E.A.5
  • 68
    • 1642504359 scopus 로고    scopus 로고
    • ATP- and adenosine-mediated signaling in the central nervous system purinergic receptor complex: generating adenine nucleotide-sensitive adenosine receptors
    • Yoshioka K., Nakata H. ATP- and adenosine-mediated signaling in the central nervous system purinergic receptor complex: generating adenine nucleotide-sensitive adenosine receptors. Journal of Pharmacological Sciences 2004, 94:88-94.
    • (2004) Journal of Pharmacological Sciences , vol.94 , pp. 88-94
    • Yoshioka, K.1    Nakata, H.2
  • 69
    • 0036229384 scopus 로고    scopus 로고
    • Interaction between carbamazepine, zonisamide and voltage-sensitive Ca2+ channel on acetylcholine release in rat frontal cortex
    • Zhu G., Okada M., Murakami T., Kawata Y., Kamata A., Kaneko S. Interaction between carbamazepine, zonisamide and voltage-sensitive Ca2+ channel on acetylcholine release in rat frontal cortex. Epilepsy Research 2002, 49(1):49-60.
    • (2002) Epilepsy Research , vol.49 , Issue.1 , pp. 49-60
    • Zhu, G.1    Okada, M.2    Murakami, T.3    Kawata, Y.4    Kamata, A.5    Kaneko, S.6
  • 70
    • 33745750361 scopus 로고    scopus 로고
    • Nucleotide signaling in nervous system development
    • Zimmermann H. Nucleotide signaling in nervous system development. European Journal of Physiology 2006, 452:573-588.
    • (2006) European Journal of Physiology , vol.452 , pp. 573-588
    • Zimmermann, H.1
  • 71
    • 33748932546 scopus 로고    scopus 로고
    • Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission
    • Zimmermann G., Soreq H. Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission. Cell and Tissue Research 2006, 326:655-669.
    • (2006) Cell and Tissue Research , vol.326 , pp. 655-669
    • Zimmermann, G.1    Soreq, H.2
  • 72
    • 0032077198 scopus 로고    scopus 로고
    • New insights into molecular structure and function of ecto-nucleotidases in the nervous system
    • Zimmermann H., Braun N., Kegel B., Heine P. New insights into molecular structure and function of ecto-nucleotidases in the nervous system. Neurochemistry International 1998, 32:421-425.
    • (1998) Neurochemistry International , vol.32 , pp. 421-425
    • Zimmermann, H.1    Braun, N.2    Kegel, B.3    Heine, P.4
  • 74
    • 9644289586 scopus 로고    scopus 로고
    • Adenosine A1 receptors and the anticonvulsant potential of drugs effective in the model of 3-nitropropionic acid-induced seizures in mice
    • Zuchora B., Wielosz M., Urbanska E.M. Adenosine A1 receptors and the anticonvulsant potential of drugs effective in the model of 3-nitropropionic acid-induced seizures in mice. European Neuropsychopharmacology 2004, 15:85-93.
    • (2004) European Neuropsychopharmacology , vol.15 , pp. 85-93
    • Zuchora, B.1    Wielosz, M.2    Urbanska, E.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.