Sertraline and clomipramine inhibit nucleotide catabolism in rat brain synaptosomes

Toxicology in Vitro

Volumn 21, Issue 4, 2007, Pages 671-676

  Pedrazza, Eduardo Luiz ^a   Senger, Mario Roberto ^b   Pedrazza, Leonardo ^a   Zimmermann, Fernanda Francine ^a   de Freitas Sarkis, João José ^b   Bonan, Carla Denise ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Adenosine; Clomipramine; Depression; Ecto 5 nucleotidase; Ecto nucleotidases; NTPDase; Sertraline

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CLOMIPRAMINE; ECTO 5' NUCLEOTIDASE; NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE; PHOSPHATASE; SERTRALINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SYNAPTOSOME; CATABOLISM; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVITY; ENZYME INHIBITION; HIPPOCAMPUS; HYDROLYSIS; MALE; NONHUMAN; NUCLEOTIDE METABOLISM; RAT;

5'-NUCLEOTIDASE; ADENOSINE DIPHOSPHATE; ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIDEPRESSIVE AGENTS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CEREBRAL CORTEX; CLOMIPRAMINE; HIPPOCAMPUS; MALE; NERVE TISSUE PROTEINS; NUCLEOSIDES; RATS; RATS, WISTAR; SERTRALINE; SYNAPTOSOMES;

RATTUS;

EID: 34047246531     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.01.006     Document Type: Article

References (40)

1. Bailly D. [Efficacy of selective serotonin reuptake inhibitor treatment in children and adolescents]. La Presse médicale 35 (2006) 1293-1302
2. Bal N., Figueras G., Vilaro M.T., Sunol C., and Artigas F. Antidepressant drugs inhibit a glial 5-hydroxytryptamine transporter in rat brain. The European Journal of Neuroscience 9 (1997) 1728-1738
3. Barcellos C.K., Schetinger M.R., Dias R.D., and Sarkis J.J. In vitro effect of central nervous system active drugs on the ATPase-ADPase activity and acetylcholinesterase activity from cerebral cortex of adult rats. General Pharmacology 31 (1998) 563-567
4. Battastini A.M., da Rocha J.B., Barcellos C.K., Dias R.D., and Sarkis J.J. Characterization of an ATP diphosphohydrolase (EC 3.6.1.5) in synaptosomes from cerebral cortex of adult rats. Neurochemical Research 16 (1991) 1303-1310
5. Bert B., Harms S., Langen B., and Fink H. Clomipramine and seleginine: do they influence impulse control?. Journal of Veterinary Pharmacology & Therapeutics 29 (2006) 41-47
6. BezchlibnyK-Butler K.Z., and Virani A.S. Clinical handbook of psychotropic drugs for children and adolescents (2004), Hogrefe & Huber Publishers pp. 77-78
7. Bigonnesse F., Levesque S.A., Kukulski F., Lecka J., Robson S.C., Fernandes M.J., and Sevigny J. Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-8. Biochemistry 11 (2004) 5511-5519
8. Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 (1976) 218-254
9. Brundege J.M., and Dunwiddie T.V. Role of adenosine as a modulator of synaptic activity in the central nervous system. Advances in Pharmacology 39 (1997) 353-391
10. Burnstock G. Cotransmission. Current Opinion on Pharmacology 4 (2004) 47-52
11. Carfagna M.A., and Muhoberac B.B. Interaction of tricyclic drug analogs with synaptic plasma membranes: structure-mechanism relationships in inhibition of neuronal Na+/K(+)-ATPase activity. Molecular Pharmacology 44 (1993) 129-141
12. 2+-stimulated ATPase activity. Analytical Biochemistry 157 (1986) 375-380
13. Cunha R.A. Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors. Neurochemistry International 38 (2001) 107-125
14. Daniel W.A., Wojcikowski J., and Palucha A. Intracellular distribution of psychotropic drugs in the grey and white matter of the brain: the role of lysosomal trapping. British Journal of Pharmacology 134 (2001) 807-814
15. Delgado P.L. Common pathways of depression and pain. The Journal of Clinical Psychiatry 65 (2004) 16-19
16. Dunwiddie T.V., and Masino S.A. The role and regulation of adenosine in the central nervous system. Annual Review of Neuroscience 24 (2001) 31-55
17. Fava M. The role of the serotonergic and noradrenergic neurotransmitter systems in the treatment of psychological and physical symptoms of depression. The Journal of Clinical Psychiatry 64 (2003) 26-29
18. Fredholm B.B., Chen J.F., Cunha R.A., Svenningsson P., and Vaugeois J.M. Adenosine and brain function. International Review of Neurobiology 63 (2005) 191-270
19. Galeotti N., Bartolini A., and Ghelardini C. Role of Gi proteins in the antidepressant-like effect of amitriptyline and clomipramine. Neuropsychopharmacology 27 (2002) 554-564
20. Giambalvo C.T., and Price L.H. Effects of fenfluramine and antidepressants on protein kinase C activity in rat cortical synaptoneurosomes. Synapse. 1 (2003) 212-222
21. Grinthal A., and Guidotti G. CD39, NTPDase 1, is attached to the plasma membrane by two transmembrane domains. Why?. Purinergic Signalling 2 (2006) 391-398
22. Harkin A., Nally R., Kelly J.P., and Leonard B.E. Effects of reboxetine and sertraline treatments alone and in combination on the binding properties of cortical NMDA and beta1-adrenergic receptors in an animal model of depression. Journal of Neural Transmission 107 (2000) 1213-1227
23. Heymann D., Reddington M., and Kreutzberg G.W. Subcellular localization of 5′ nucleotidase in rat brain. Journal of Neurochemistry 43 (1984) 971-978
24. Kaster M.P., Rosa A.O., Rosso M.M., Goulart E.C., Santos A.R., and Rodrigues A.L. Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors. Neuroscience Letters 23 (2004) 21-24
25. Lundbaek J.A., Birn P., Hansen A.J., Sogaard R., Nielsen C., Girshman J., Bruno M.J., Tape S.E., Egebjerg J., Greathouse D.V., Mattice G.L., Koeppe R.E., and Andersen O.S. Regulation of sodium channel function by bilayer elasticity: the importance of hydrophobic coupling. Effects of Micelle-forming amphiphiles and cholesterol. The Journal of General Physiology 123 (2004) 591-621
26. Nag D., and Ghosh J.J. Imipramine-induced changes of brain adenosine triphosphatase activity. Journal of Neurochemistry 20 (1973) 1021-1027
27. Nagy A., and Delgado-Escueta A.V. Rapid preparation of synaptosomes from mammalian brain using nontoxic isoosmotic gradient material (Percoll). Journal of Neurochemistry 43 (1984) 1114-1123
28. Okada M., Kawata Y., Murakami T., Wada K., Mizuno K., Kondo T., and Kaneko S. Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin. The European Journal of Neuroscience 11 (1999) 1-9
29. Papanikolaou A., Papafotika A., Murphy C., Papamarcaki T., Tsolas O., Drab M., Kurzchalia T.V., Kasper M., and Christoforidis S. Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39. Journal of Biological Chemistry 15 (2005) 26406-26414
30. Phillis J.W. Potentiation of the action of adenosine on cerebral cortical neurones by the tricyclic antidepressants. British Journal of Pharmacology 83 (1984) 567-575
31. Phillis J.W., and Wu P.H. The effect of various centrally active drugs on adenosine uptake by the central nervous system. Comparative Biochemistry and Physiology 72 (1982) 179-187
32. Ralevic V., and Burnstock G. Receptors for purines and pyrimidines. Pharmacological Reviews 50 (1998) 413-492
33. Robson S.C., Sévigny J., and Zimmermann H. The E-NTPDase family of ectonucleotidases: structure function relationships and pathophysiological significance. Purinergic Signalling 2 (2006) 409-430
34. Sanganahalli B.G., Joshi P.G., and Joshi N.B. Differential effects of tricyclic antidepressant drugs on membrane dynamics - a fluorescence spectroscopic study. Life Sciences 68 (2000) 81-90
35. Sobocki P., Jonsson B., Angst J., and Rehnberg C. Cost of depression in Europe. The Journal of Mental Health Policy and Economics 9 (2006) 87-98
36. Souza M.E., Polizello A.C., Uyemura S.A., Castro-Silva O., and Curti C. Effect of fluoxetine on rat liver mitochondria. Biochemical Pharmacology 48 (1994) 535-541
37. Sträter N. Ecto-5′-nucleotidase: structure function relationships. Purinergic Signalling 2 (2006) 343-350
38. Trivedi J.K., Sharma S., and Tandon R. Depression in general clinical practice. Journal of the Indian Medical Association 102 (2004) 557-558 561
39. Zanatta L.M., Nascimento F.C., Barros S.V., Silva G.R., Zugno A.I., Netto C.A., and Wyse A.T. In vivo and in vitro effect of imipramine and fluoxetine on Na+,K+-ATPase activity in synaptic plasma membranes from the cerebral cortex of rats. Brazilian Journal of Medical and Biological Research 34 (2001) 1265-1269
40. Zimmermann H. Ecto-nucleotidases: some recent developments and a note on nomenclature. Drug Development Research 52 (2001) 44-56