Oral administration of a GSK3 inhibitor increases brain insulin-like growth factor I levels

Journal of Biological Chemistry

Volumn 285, Issue 23, 2010, Pages 17693-17700

  Bolós, Marta ^a   Fernandez, Silvia ^a   Torres Aleman, Ignacio ^a  

^a CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER; ALZHEIMER DISEASE; C-TERMINAL REGIONS; DRUG TARGETS; INSULIN-LIKE GROWTH FACTOR-I; KEY REGULATORS; NEURODEGENERATION; NEURODEGENERATIVE; NEUROTROPHIC; ORAL ADMINISTRATION; SERUM INSULIN; SRC HOMOLOGY 3 DOMAINS; THERAPEUTIC EFFICACY; TRANSMEMBRANE REGIONS; TRANSPORT MECHANISM; WILD TYPES;

BIOACTIVITY; INSULIN; PEPTIDES;

BODY FLUIDS;

ALBUMIN; AMYLOID PRECURSOR PROTEIN; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; MEGALIN; NP 12; PRESENILIN 1; PROTEIN SH3; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; INTERNALIZATION; MALE; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; TRANSCYTOSIS;

ADMINISTRATION, ORAL; ALZHEIMER DISEASE; ANIMALS; BRAIN; DOGS; GLYCOGEN SYNTHASE KINASE 3; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NERVE GROWTH FACTORS; RATS; RATS, WISTAR; RECEPTORS, LIPOPROTEIN;

MUS;

EID: 77952936812     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.096594     Document Type: Article

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