MnSOD activity protects mitochondrial morphology of quiescent fibroblasts from age associated abnormalities

Mitochondrion

Volumn 10, Issue 4, 2010, Pages 342-349

  Sarsour, Ehab H ^a   Goswami, Monali ^a   Kalen, Amanda L ^a   Goswami, Prabhat C ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Aging; Chronological life span; Mitochondria; MnSOD; Quiescent growth; ROS

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; MANGANESE SUPEROXIDE DISMUTASE; OXYGEN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL AGING; CELL DAMAGE; CELL FUNCTION; CELL GROWTH; CELL POPULATION; CELL PROLIFERATION; CELL PROTECTION; CELL VACUOLE; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FIBROBLAST CULTURE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL VOLUME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; CELL DIVISION; CELLS, CULTURED; FIBROBLASTS; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 77952884070     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2010.02.004     Document Type: Article

References (37)

1. Allsopp R.C., Vaziri H., et al. Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl. Acad. Sci. USA 1992, 89:10114-10118.
2. Asikainen T.M., Huang T.T., et al. Increased sensitivity of homozygous Sod2 mutant mice to oxygen toxicity. Free Radical Biol. Med. 2002, 32:175-186.
3. Balaban R.S., Nemoto S., Finkel T. Mitochondria, oxidants, and aging. Cell 2005, 120:483-495.
4. Beauchamp C., Fridovich I. Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal. Biochem. 1971, 44:276-287.
5. Borgstahl G.E., Parge H.E., et al. The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles [erratum appears in Cell 1993 Feb 12;72(3): following 476]. Cell 1992, 71:107-118.
6. Boveris A. Mitochondrial production of superoxide radical and hydrogen peroxide. Adv. Exp. Med. Biol. 1977, 78:67-82.
7. Campisi J. Replicative senescence. an old lives' tale?. Cell 1996, 84:497-500.
8. Campisi J. Cancer, aging and cellular senescence. In Vivo 2000, 14:183-188.
9. Chance B. Electron transfer: pathways, mechanisms, and controls. Ann. Rev. Biochem. 1977, 46:967-980.
10. Chance B., Sies H., Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 1979, 59:527-605.
11. Davidson B.L., Allen E.D., et al. A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nat. Genet. 1993, 3:219-223.
12. Finch C.E. The biology of aging in model organisms. Alzheimer Dis. Assoc. Disord. 2003, 17(Suppl. 2):S39-S41.
13. Finkel T., Holbrook N.J. Oxidants, oxidative stress and the biology of ageing. Nature 2000, 408:239-247.
14. Harley C.B., Vaziri H., Counter C.M., Allsopp R.C. The telomere hypothesis of cellular aging. Exp. Gerontol. 1992, 27:375-382.
15. Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 1956, 11:298-300.
16. Harris N., Costa V., et al. Mnsod overexpression extends the yeast chronological (G(0)) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells. Free Radical Biol. Med. 2003, 34:1599-1606.
17. Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 1965, 37:614-636.
18. Hayflick L. Current theories of biological aging. Fed. Proc. 1975, 34:9-13.
19. Hayflick L., Moorhead P.S. The serial cultivation of human diploid cell strains. Exp. Cell Res. 1961, 25:585-621.
20. Li Y., Huang T.T., et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat. Genet. 1995, 11:376-381.
21. Liu R., Oberley T.D., Oberley L.W. Transfection and expression of MnSOD cDNA decreases tumor malignancy of human oral squamous carcinoma SCC-25 cells. Hum. Gene Ther. 1997, 8:585-595.
22. Melov S., Schneider J.A., et al. A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase.[see comment]. Nat. Genet. 1998, 18:159-163.
23. Melov S., Doctrow S.R., et al. Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics. J. Neurosci. 2001, 21:8348-8353.
24. Orr W.C., Sohal R.S. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 1994, 263:1128-1130.
25. Packer L., Fuehr K. Low oxygen concentration extends the lifespan of cultured human diploid cells. Nature 1977, 267:423-425.
26. Perez V.I., Van Remmen H., et al. The overexpression of major antioxidant enzymes does not extend the lifespan of mice. Aging Cell 2009, 8:73-75.
27. Presley A.D., Fuller K.M., Arriaga E.A. MitoTracker Green labeling of mitochondrial proteins and their subsequent analysis by capillary electrophoresis with laser-induced fluorescence detection. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2003, 793:141-150.
28. Saito H., Hammond A.T., Moses R.E. The effect of low oxygen tension on the in vitro-replicative life span of human diploid fibroblast cells and their transformed derivatives. Exp. Cell Res. 1995, 217:272-279.
29. Sarsour E.H., Agarwal M., et al. Manganese superoxide dismutase protects the proliferative capacity of confluent normal human fibroblasts. J. Biol. Chem. 2005, 280:18033-18041.
30. Sarsour E.H., Venkataraman S., et al. Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth. Aging Cell 2008, 7:405-417.
31. Schriner S.E., Linford N.J., et al. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 2005, 308:1909-1911.
32. Serrano M., Blasco M.A. Putting the stress on senescence [erratum appears in Curr. Opin. Cell Biol. 2002 Feb;14(1):123]. Curr. Opin. Cell Biol. 2001, 13:748-753.
33. Singh K.K. Mitochondria damage checkpoint, aging, and cancer. Ann. NY Acad. Sci. 2006, 1067:182-190.
34. Smith J.R., Pereira-Smith O.M. Replicative senescence: implications for in vivo aging and tumor suppression [see comment]. Science 1996, 273:63-67.
35. Staniek K., Nohl H. Are mitochondria a permanent source of reactive oxygen species?. Biochim. Biophys. Acta 2000, 1460:268-275.
36. St-Pierre J., Buckingham J.A., Roebuck S.J., Brand M.D. Topology of superoxide production from different sites in the mitochondrial electron transport chain. J. Biol. Chem. 2002, 277:44784-44790.
37. Wright W.E., Shay J.W. Historical claims and current interpretations of replicative aging [see comment]. Nat. Biotechnol. 2002, 20:682-688.