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Volumn 101, Issue 1, 2010, Pages 35-47

Aspirin and clopidogrel resistance: Should we worry about?

Author keywords

Aspirin; Coronary artery disease, prevention and control; Platelet aggregation inhibitors

Indexed keywords

11 OXOTHROMBOXANE B2; ACETYLSALICYLIC ACID; ALPHA2 INTEGRIN; BETA1 INTEGRIN; CLOPIDOGREL; COLLAGEN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GLYCOPROTEIN IB; IBUPROFEN; NAPROXEN; PRASUGREL; PROSTAGLANDIN E1; PURINERGIC P2Y12 RECEPTOR; THROMBOXANE A2; THROMBOXANE B2; TICAGRELOR; VASODILATOR STIMULATED PHOSPHOPROTEIN; VON WILLEBRAND FACTOR;

EID: 77952866908     PISSN: 00264806     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (8)

References (78)
  • 1
    • 0037271306 scopus 로고    scopus 로고
    • Scientific and therapeutic advances in antiplatelet therapy
    • DOI 10.1038/nrd985
    • Bhatt D, Topol EJ. Scientific and therapeutic advances in antiplatelet therapy. Nature Rev 2003;2:15-28. (Pubitemid 37361621)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.1 , pp. 15-28
    • Bhatt, D.L.1    Topol, E.J.2
  • 2
    • 17144396926 scopus 로고    scopus 로고
    • Platelet function testing in cardiovascular diseases
    • Michelson AD. Platelet function testing in cardiovascular diseases. Circulation 2004;110:489-493
    • (2004) Circulation , vol.110 , pp. 489-493
    • Michelson, A.D.1
  • 3
    • 0141851094 scopus 로고    scopus 로고
    • Aspirin resistance: Definition, mechanisms and clinical read-outs
    • Patrono C. Aspirin resistance: definition, mechanisms and clinical read-outs. J Thromb Haemost 2003;1:1710-1713
    • (2003) J Thromb Haemost , vol.1 , pp. 1710-1713
    • Patrono, C.1
  • 4
    • 0031978582 scopus 로고    scopus 로고
    • Eicosanoids and iso-eicosanoids: Constitutive, inducible and transcellular biosynthesis in vascular disease
    • Maclouf J, Folco G, Patrono C. Eicosanoids and iso-eicosanoids: constitutive, inducible and transcellular biosynthesis in vascular disease. Thromb Haemost 1998;79:691-705.
    • (1998) Thromb Haemost , vol.79 , pp. 691-705
    • Maclouf, J.1    Folco, G.2    Patrono, C.3
  • 5
    • 0029664422 scopus 로고    scopus 로고
    • Cyclooxygenases-1 and -2 of endothelial cells utilize exogenous or endogenous arachidonic acid for transcellular production of thromboxane
    • DOI 10.1074/jbc.271.20.12042
    • Karim S, Habib A, Levy-Toledano S, Maclouf J. Cyclooxygenase-1 and -2 of endothelial cells utilize exogenous or endogenous arachidonic acid for transcellular production of thromboxane. J Biol Chem 1996;271: 12042-12048 (Pubitemid 26157282)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.20 , pp. 12042-12048
    • Karim, S.1    Habib, A.2    Levy-Toledano, S.3    Maclouf, J.4
  • 7
    • 0345040152 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in human platelets as a possible factor in aspirin resistance
    • Weber AA, Zimmermann KC, Meyer-Kirchrath J, Schrör K. Cylcooxygenase-2 in human platelets as a possible factor in aspirin resistance. Lancet 1999;353:900. (Pubitemid 29126885)
    • (1999) Lancet , vol.353 , Issue.9156 , pp. 900
    • Weber, A.-A.1    Zimmermann, K.C.2    Meyer-Kirchrath, J.3    Schror, K.4
  • 8
    • 9144270451 scopus 로고    scopus 로고
    • Expert consensus document on the use of antiplatelet agents. The Task Force on the Use of Antiplatelet Agents in Patients with Atherosclerotic Cardiovascular Disease of the European Society of Cardiology
    • Patrono C, Bachmann F, Baigent C, et al.. Expert consensus document on the use of antiplatelet agents. The Task Force on the Use of Antiplatelet Agents in Patients with Atherosclerotic Cardiovascular Disease of the European Society of Cardiology. Eur Heart J 2004;25:166-181
    • (2004) Eur Heart J , vol.25 , pp. 166-181
    • Patrono, C.1    Bachmann, F.2    Baigent, C.3
  • 10
    • 8344231455 scopus 로고    scopus 로고
    • Aspirin and clopidogrel. Efficacy, safety and the issue of drug resistance
    • Cattaneo M. Aspirin and clopidogrel. Efficacy, safety and the issue of drug resistance. Arterioscler Thromb Vasc Biol 2004;24:1980-1987
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1980-1987
    • Cattaneo, M.1
  • 11
    • 0030851305 scopus 로고    scopus 로고
    • A comparison of the effects of aspirin on bleeding time measured during the SimplateTM method and closure time measured using the PDA-100TM, in healthy volunteers
    • Marshall PW, Williams AJ, Dixon RM, et al.. A comparison of the effects of aspirin on bleeding time measured during the SimplateTM method and closure time measured using the PDA-100TM, in healthy volunteers. Br J Pharmacol 1997;44:151-155
    • (1997) Br J Pharmacol , vol.44 , pp. 151-155
    • Marshall, P.W.1    Williams, A.J.2    Dixon, R.M.3
  • 13
    • 2942555599 scopus 로고    scopus 로고
    • Assessing aspirin responsiveness in subjects with multiple risk factors for vascular disease with a rapid platelet function analyzer
    • DOI 10.1097/00001721-200406000-00002
    • Malinin A, Spergling M, Muhlestein B, Steinhubl S, Serebruany V. Assessing aspirin responsiveness in subjects with multiple risk factors for vascular disease with a rapid platelet function analyzer. Blood Coagul Fibrinolysis 2004;15:295-301. (Pubitemid 38757056)
    • (2004) Blood Coagulation and Fibrinolysis , vol.15 , Issue.4 , pp. 295-301
    • Malinin, A.1    Spergling, M.2    Muhlestein, B.3    Steinhubl, S.4    Serebruany, V.5
  • 14
    • 12244255075 scopus 로고    scopus 로고
    • Effect of a single dose aspirin on platelets in humans with multiple risk factors for coronary artery disease
    • DOI 10.1016/S0014-2999(02)02956-4
    • Malinin AI, Atar D, Callahan KP, McKenzie ME, Serebruany V. Effect of a single dose aspirin on platelets in humans with multiple risk factors for coronary artery disease. Eur J Pharmacol 2003;462:139-143 (Pubitemid 36183745)
    • (2003) European Journal of Pharmacology , vol.462 , Issue.1-3 , pp. 139-143
    • Malinin, A.I.1    Atar, D.2    Callahan, K.P.3    McKenzie, M.E.4    Serebruany, V.L.5
  • 15
    • 34547760330 scopus 로고    scopus 로고
    • A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease
    • DOI 10.1093/eurheartj/ehm226
    • Lordkipanidzé M, Pharand C, Schampaert E, Turgeon J, Palisaitis DA, Diodati JG. A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease. Eur Heart J 2007;28:1702-1708 (Pubitemid 47227104)
    • (2007) European Heart Journal , vol.28 , Issue.14 , pp. 1702-1708
    • Lordkipanidze, M.1    Pharand, C.2    Schampaert, E.3    Turgeon, J.4    Palisaitis, D.A.5    Diodati, J.G.6
  • 16
    • 10744228434 scopus 로고    scopus 로고
    • Lack of aspirin effect:aspirin resistance or resistance to taking aspirin?
    • Cotter G, Shemesh E, Zehavi M, Dinur I, Rudnick A, Milo O et al. Lack of aspirin effect:aspirin resistance or resistance to taking aspirin? Am Heart J 2004;147:293-300.
    • (2004) Am Heart J , vol.147 , pp. 293-300
    • Cotter, G.1    Shemesh, E.2    Zehavi, M.3    Dinur, I.4    Rudnick, A.5    Milo, O.6
  • 17
    • 64649091484 scopus 로고    scopus 로고
    • Aspirin noncompliance is the major cause of "aspirin resistance" in patients undergoing coronary stenting
    • Cuisset T, Frere C, Quilici J, Gaborit B, Bali L, Poyet R et al. Aspirin noncompliance is the major cause of "aspirin resistance" in patients undergoing coronary stenting. Am Heart J 2009;157:889-893
    • (2009) Am Heart J , vol.157 , pp. 889-893
    • Cuisset, T.1    Frere, C.2    Quilici, J.3    Gaborit, B.4    Bali, L.5    Poyet, R.6
  • 18
    • 16844362580 scopus 로고    scopus 로고
    • Compliance as a critical consideration in patients who appear to be resistant to aspirin after healing of myocardial infarction
    • DOI 10.1016/j.amjcard.2004.12.038
    • Schwartz KA, Schwartz DE, Ghosheh K, Reeves MJ, Barber K, DeFranco A. Compliance as a critical consideration in patients who appear to be resistant to aspirin after healing of myocardial infarction. Am J Cardiol 2005;95:973-975 (Pubitemid 40487749)
    • (2005) American Journal of Cardiology , vol.95 , Issue.8 , pp. 973-975
    • Schwartz, K.A.1    Schwartz, D.E.2    Ghosheh, K.3    Reeves, M.J.4    Barber, K.5    Defranco, A.6
  • 19
    • 27444434164 scopus 로고    scopus 로고
    • Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachidonic acid stimulation
    • Tantry US, Bliden KP, Gurbel PA. Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachidonic acid stimulation. J Am Coll Cardiol 2005;46:1705-1709
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1705-1709
    • Tantry, U.S.1    Bliden, K.P.2    Gurbel, P.A.3
  • 20
    • 0141919739 scopus 로고    scopus 로고
    • Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes:Observations from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) study
    • Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) Trial Investigators
    • Peters RJ, Mehta SR, Fox KA, Zhao F, Lewis BS, Kopecky SL et al. Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) Trial Investigators. Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes:observations from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) study. Circulation 2003;108:1682-1687
    • (2003) Circulation , vol.108 , pp. 1682-1687
    • Peters, R.J.1    Mehta, S.R.2    Fox, K.A.3    Zhao, F.4    Lewis, B.S.5    Kopecky, S.L.6
  • 22
    • 0021838191 scopus 로고
    • Low-dose aspirin in patients recovering from myocardial infarction. Evidence for a selective inhibition of thromboxane-related platelet function
    • De Caterina R, Giannessi D, Bernini W, Gazzetti P, Michelassi C, L'Abbate A et al. Low-dose aspirin in patients recovering from myocardial infarction. Evidence for a selective inhibition of thromboxane-related platelet function. Eur Heart J 1985;6:409-417
    • (1985) Eur Heart J , vol.6 , pp. 409-417
    • De Caterina, R.1    Giannessi, D.2    Bernini, W.3    Gazzetti, P.4    Michelassi, C.5    L'Abbate, A.6
  • 23
    • 77952824613 scopus 로고    scopus 로고
    • Organisation to Assess Strategies for Ischemic Syndromes (OASIS)-7 Results, Oral Communication
    • Mehta S. Organisation to Assess Strategies for Ischemic Syndromes (OASIS)-7 Results, Oral Communication. ESC Congress, Barcelona 2009.
    • ESC Congress, Barcelona 2009
    • Mehta, S.1
  • 24
    • 0021918123 scopus 로고
    • Clinical pharmacokinetics of the salicylates
    • Needs CJ, Brooks PM. Clinical pharmacokinetics of the salicylates. Clin Pharmacokinet 1985;10:164-177
    • (1985) Clin Pharmacokinet , vol.10 , pp. 164-177
    • Needs, C.J.1    Brooks, P.M.2
  • 26
    • 0041572921 scopus 로고    scopus 로고
    • Functional and biochemical evaluation of platelet aspirin resistance after coronary artery bypass surgery
    • DOI 10.1161/01.CIR.0000081770.51929.5A
    • Zimmermann N, Wenk A, Kim U, Kienzle P, Weber AA, Gams E et al. Functional and biochemical evaluation of platelet aspirin resistance after coronary artery bypass surgery. Circulation 2003;108:542-547 (Pubitemid 36961167)
    • (2003) Circulation , vol.108 , Issue.5 , pp. 542-547
    • Zimmermann, N.1    Wenk, A.2    Kim, U.3    Kienzle, P.4    Weber, A.-A.5    Gams, E.6    Schror, K.7    Hohlfeld, T.8
  • 27
    • 0037046196 scopus 로고    scopus 로고
    • Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
    • DOI 10.1161/01.CIR.0000013777.21160.07
    • Eikelboom JW, Hirsh J, Weitz JI, Johnston M, Yi Q, Yusuf S. Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 2002;105:1650-1655 (Pubitemid 34298607)
    • (2002) Circulation , vol.105 , Issue.14 , pp. 1650-1655
    • Eikelboom, J.W.1    Hirsh, J.2    Weitz, J.I.3    Johnston, M.4    Yi, Q.5    Yusuf, S.6
  • 28
    • 55449132867 scopus 로고    scopus 로고
    • Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid:Determinants and effect on cardiovascular risk
    • Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA) Investigators
    • Eikelboom JW, Hankey GJ, Thorn J, Bhatt DL, Steg PG, Montalescot G et al. Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA) Investigators. Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid:determinants and effect on cardiovascular risk. Circulation 2008;118:1705-1712
    • (2008) Circulation , vol.118 , pp. 1705-1712
    • Eikelboom, J.W.1    Hankey, G.J.2    Thorn, J.3    Bhatt, D.L.4    Steg, P.G.5    Montalescot, G.6
  • 29
    • 0037454168 scopus 로고    scopus 로고
    • A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease
    • DOI 10.1016/S0735-1097(02)03014-0
    • Gum PA, Kottke-Marchant K, Welsh PA, White J, Topol EJ. A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol 2003;41:961-965 (Pubitemid 36315537)
    • (2003) Journal of the American College of Cardiology , vol.41 , Issue.6 , pp. 961-965
    • Gum, P.A.1    Kottke-Marchant, K.2    Welsh, P.A.3    White, J.4    Topol, E.J.5
  • 30
    • 0027279350 scopus 로고
    • Two-year follow-up of aspirin responder and aspirin non responder. A pilot-study including 180 post-stroke patients
    • Grotemeyer KH, Scharafinski HW, Husstedt IW. Two-year follow-up of aspirin responder and aspirin non responder. A pilot-study including 180 post-stroke patients. Thromb Res 1993;71:397-403.
    • (1993) Thromb Res , vol.71 , pp. 397-403
    • Grotemeyer, K.H.1    Scharafinski, H.W.2    Husstedt, I.W.3
  • 31
    • 1542708471 scopus 로고    scopus 로고
    • Aspirin resistance is associated with a high incidence of myonecrosis after non-urgent percutaneous coronary intervention despite clopidogrel pretreatment
    • DOI 10.1016/j.jacc.2003.12.034, PII S0735109704001731
    • Chen WH, Lee PY, Ng W, Tse HF, Lau CP. Aspirin resistance is associated with a high incidence of myonecrosis after nonurgent percutaneous coronary intervention despite clopidogrel pretreatment. J Am Coll Cardiol 2004;43:1122-1126 (Pubitemid 38353000)
    • (2004) Journal of the American College of Cardiology , vol.43 , Issue.6 , pp. 1122-1126
    • Chen, W.-H.1    Lee, P.-Y.2    Ng, W.3    Tse, H.-F.4    Lau, C.-P.5
  • 32
    • 0037276966 scopus 로고    scopus 로고
    • Aspirin non-responder status in patients with recurrent cerebral ischemic attacks
    • DOI 10.1007/s00415-003-0954-y
    • Grundmann K, Jaschonek K, Kleine B, Dichgans J, Topka H. Aspirin non-responder status in patients with recurrent cerebral ischemic attacks. J Neurol 2003;250:63-66 (Pubitemid 36206686)
    • (2003) Journal of Neurology , vol.250 , Issue.1 , pp. 63-66
    • Grundmann, K.1    Jaschonek, K.2    Kleine, B.3    Dichgans, J.4    Topka, H.5
  • 33
    • 73949093109 scopus 로고    scopus 로고
    • Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization
    • Frelinger AL 3rd, Li Y, Linden MD, Barnard MR, Fox ML, Christie DJ et al. Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. Circulation 2009;120:2586-2596
    • (2009) Circulation , vol.120 , pp. 2586-2596
    • Frelinger III, A.L.1    Li, Y.2    Linden, M.D.3    Barnard, M.R.4    Fox, M.L.5    Christie, D.J.6
  • 35
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting:Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • Gurbel PA, Bliden KP, Hiatt BL, O'Connor CM. Clopidogrel for coronary stenting:response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation 2003;107:2908-2913
    • (2003) Circulation , vol.107 , pp. 2908-2913
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3    O'Connor, C.M.4
  • 37
    • 53449098101 scopus 로고    scopus 로고
    • Dose effect of clopidogrel reloading in patients already on 75-mg maintenance dose:The Reload with Clopidogrel before Coronary Angioplasty in Subjects Treated Long Term with Dual Antiplatelet Therapy (RELOAD) study
    • Collet JP, Silvain J, Landivier A, Tanguy ML, Cayla G, Bellemain A et al. Dose effect of clopidogrel reloading in patients already on 75-mg maintenance dose:the Reload with Clopidogrel Before Coronary Angioplasty in Subjects Treated Long Term with Dual Antiplatelet Therapy (RELOAD) study. Circulation 2008;118:1225-1233
    • (2008) Circulation , vol.118 , pp. 1225-1233
    • Collet, J.P.1    Silvain, J.2    Landivier, A.3    Tanguy, M.L.4    Cayla, G.5    Bellemain, A.6
  • 38
    • 0032873146 scopus 로고    scopus 로고
    • Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets. Definition and detection of ticlopidine/clopidogrel effects
    • Schwarz UR, Geiger J, Walter U, Eigenthaler M. Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets - definition and detection of ticlopidine/clopidogrel effects. Thromb Haemost 1999;82:1145-1152 (Pubitemid 29419734)
    • (1999) Thrombosis and Haemostasis , vol.82 , Issue.3 , pp. 1145-1152
    • Schwarz, U.R.1    Geiger, J.2    Walter, U.3    Eigenthaler, M.4
  • 39
    • 15944383861 scopus 로고    scopus 로고
    • Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases
    • DOI 10.1111/j.1538-7836.2004.01063.x
    • Aleil B, Ravanat C, Cazenave JP, Rochoux G, Heitz A, Gachet C. Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases. J Thromb Haemost 2005;3:85-92. (Pubitemid 41647119)
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.1 , pp. 85-92
    • Aleil, B.1    Ravanat, C.2    Cazenave, J.P.3    Rochoux, G.4    Heitz, A.5    Gachet, C.6
  • 40
    • 33646441600 scopus 로고    scopus 로고
    • Correlation of a new point-of-care test with conventional optical aggregometry for the assessment of clopidogrel responsiveness
    • von Beckerath N, Pogatsa-Murray G, Wieczorek A, Sibbing D, Schömig A, Kastrati A. Correlation of a new point-of-care test with conventional optical aggregometry for the assessment of clopidogrel responsiveness. Thromb Haemost 2006;95:910-911
    • (2006) Thromb Haemost , vol.95 , pp. 910-911
    • Von Beckerath, N.1    Pogatsa-Murray, G.2    Wieczorek, A.3    Sibbing, D.4    Schömig, A.5    Kastrati, A.6
  • 41
    • 38349090725 scopus 로고    scopus 로고
    • Assessment of ADP-induced platelet aggregation with light transmission aggregometry and multiple electrode platelet aggregometry before and after clopidogrel treatment
    • Sibbing D, Braun S, Jawansky S, Vogt W, Mehilli J, Schömig A et al. Assessment of ADP-induced platelet aggregation with light transmission aggregometry and multiple electrode platelet aggregometry before and after clopidogrel treatment. Thromb Haemost 2008;99:121.
    • (2008) Thromb Haemost , vol.99 , pp. 121
    • Sibbing, D.1    Braun, S.2    Jawansky, S.3    Vogt, W.4    Mehilli, J.5    Schömig, A.6
  • 42
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Matetzky S, Shenkman B, Guetta V, Shechter M, Bienart R, Goldenberg I et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation 2004;109:3171-3175
    • (2004) Circulation , vol.109 , pp. 3171-3175
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3    Shechter, M.4    Bienart, R.5    Goldenberg, I.6
  • 43
    • 33645982865 scopus 로고    scopus 로고
    • High post-treatment platelet reactivity identified low-responders to dual antiplatelet therapy at increased risk of recurrent cardiovascular events after stenting for acute coronary syndrome
    • Cuisset T, Frere C, Quilici J, Barbou F, Morange PE, Hovasse T et al. High post-treatment platelet reactivity identified low-responders to dual antiplatelet therapy at increased risk of recurrent cardiovascular events after stenting for acute coronary syndrome. J Thromb Haemost 2006;4:542-549
    • (2006) J Thromb Haemost , vol.4 , pp. 542-549
    • Cuisset, T.1    Frere, C.2    Quilici, J.3    Barbou, F.4    Morange, P.E.5    Hovasse, T.6
  • 46
    • 0038291914 scopus 로고    scopus 로고
    • Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement
    • Muller I, Besta F, Schulz C, Massberg S, Schonig A, Gawaz M. Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement. Thromb Haemost 2003;89:783-787 (Pubitemid 36603418)
    • (2003) Thrombosis and Haemostasis , vol.89 , Issue.5 , pp. 783-787
    • Muller, I.1    Besta, F.2    Schulz, C.3    Massberg, S.4    Schonig, A.5    Gawaz, M.6
  • 49
    • 34447636769 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events
    • DOI 10.1111/j.1538-7836.2007.02609.x
    • Bonello L, Paganelli F, Arpin-Bornet M, Auquier P, Sampol J, Dignat-George F et al. asodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of post-procedural major adverse cardiovascular events. J Thromb Haemost 2007;5:1630-1636 (Pubitemid 47091403)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.8 , pp. 1630-1636
    • Bonello, L.1    Paganelli, F.2    Arpin-Bornet, M.3    Auquier, P.4    Sampol, J.5    Dignat-George, F.6    Barragan, P.7    Camoin-Jau, L.8
  • 50
    • 58049213577 scopus 로고    scopus 로고
    • Flow cytometric assessment of vasodilator-stimulated phosphoprotein: Prognostic value of recurrent cardiovascular events after acute coronary syndromes
    • Cayla G, Macia JC, Rabesandratana H, Roubille F, Gervasoni R, Pasquie JL et al. Flow cytometric assessment of vasodilator-stimulated phosphoprotein: prognostic value of recurrent cardiovascular events after acute coronary syndromes. Arch Cardiovasc Dis 2008;101:743-751
    • (2008) Arch Cardiovasc Dis , vol.101 , pp. 743-751
    • Cayla, G.1    Macia, J.C.2    Rabesandratana, H.3    Roubille, F.4    Gervasoni, R.5    Pasquie, J.L.6
  • 52
    • 59849120163 scopus 로고    scopus 로고
    • Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay:A 12-month follow-up
    • Marcucci R, Gori AM, Paniccia R, Giusti B, Valente S, Giglioli C et al. Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay:a 12-month follow-up. Circulation 2009;119:237-242
    • (2009) Circulation , vol.119 , pp. 237-242
    • Marcucci, R.1    Gori, A.M.2    Paniccia, R.3    Giusti, B.4    Valente, S.5    Giglioli, C.6
  • 53
    • 51649108832 scopus 로고    scopus 로고
    • Point-of-care measurement of clopidogrel responsiveness predicts clinical outcome in patients undergoing percutaneous coronary intervention results of the ARMYDA-PRO (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Platelet Reactivity Predicts Outcome) study
    • Patti G, Nusca A, Mangiacapra F, Gatto L, D'Ambrosio A, Di Sciascio G. Point-of-care measurement of clopidogrel responsiveness predicts clinical outcome in patients undergoing percutaneous coronary intervention results of the ARMYDA-PRO (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Platelet Reactivity Predicts Outcome) study. J Am Coll Cardiol 2008;52:1128-1133
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1128-1133
    • Patti, G.1    Nusca, A.2    Mangiacapra, F.3    Gatto, L.4    D'Ambrosio, A.5    Di Sciascio, G.6
  • 55
    • 66349133650 scopus 로고    scopus 로고
    • Cytochrome P450 genetic polymorphisms and the response to prasugrel:Relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes
    • Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT et al. Cytochrome P450 genetic polymorphisms and the response to prasugrel:relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes. Circulation 2009;119:2553-2560
    • (2009) Circulation , vol.119 , pp. 2553-2560
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3    Shen, L.4    Hockett, R.D.5    Brandt, J.T.6
  • 56
    • 58249135635 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction:A cohort study
    • Collet JP, Hulot JS, Pena A, Villard E, Esteve JB, Silvain J et al. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction:a cohort study. Lancet 2009;373:309-317
    • (2009) Lancet , vol.373 , pp. 309-317
    • Collet, J.P.1    Hulot, J.S.2    Pena, A.3    Villard, E.4    Esteve, J.B.5    Silvain, J.6
  • 59
    • 65249145201 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention
    • Sibbing D, Stegherr J, Latz W, Koch W, Mehilli J, Dorrler K et al. Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention. Eur Heart J 2009;30:916-922
    • (2009) Eur Heart J , vol.30 , pp. 916-922
    • Sibbing, D.1    Stegherr, J.2    Latz, W.3    Koch, W.4    Mehilli, J.5    Dorrler, K.6
  • 61
    • 0038300483 scopus 로고    scopus 로고
    • Impact of angina class on inhibition of platelet aggregation following clopidogrel loading in patients undergoing coronary intervention:Do we need more aggressive dosing regimens in unstable angina?
    • Soffer D, Moussa I, Harjai KJ, Boura JA, Dixon SR, Grines CL et al. Impact of angina class on inhibition of platelet aggregation following clopidogrel loading in patients undergoing coronary intervention:do we need more aggressive dosing regimens in unstable angina? Catheter Cardiovasc Interv 2003;59:21-25
    • (2003) Catheter Cardiovasc Interv , vol.59 , pp. 21-25
    • Soffer, D.1    Moussa, I.2    Harjai, K.J.3    Boura, J.A.4    Dixon, S.R.5    Grines, C.L.6
  • 65
    • 54349121974 scopus 로고    scopus 로고
    • Calcium-channel blockers reduce the antiplatelet effect of clopidogrel
    • Siller-Matula JM, Lang I, Christ G, Jilma B. Calcium-channel blockers reduce the antiplatelet effect of clopidogrel. J Am Coll Cardiol 2008;52:1557-1563
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1557-1563
    • Siller-Matula, J.M.1    Lang, I.2    Christ, G.3    Jilma, B.4
  • 66
    • 38349065084 scopus 로고    scopus 로고
    • Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: The randomized, double-blind OCLA (Omeprazole Clopidogrel Aspirin) study
    • Gilard M, Arnaud B, Cornily JC, Le Gal G, Lacut K, Le Calvez G et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole Clopidogrel Aspirin) study. J Am Coll Cardiol 2008;51:256-260
    • (2008) J Am Coll Cardiol , vol.51 , pp. 256-260
    • Gilard, M.1    Arnaud, B.2    Cornily, J.C.3    Le Gal, G.4    Lacut, K.5    Le Calvez, G.6
  • 67
    • 62649164844 scopus 로고    scopus 로고
    • A population-based study of the drug interaction between proton pump inhibitors and clopidogrel
    • Juurlink DN, Gomes T, Ko DT, Szmitko PE, Austin PC, Tu JV et al. A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ 2009;180:713-718
    • (2009) CMAJ , vol.180 , pp. 713-718
    • Juurlink, D.N.1    Gomes, T.2    Ko, D.T.3    Szmitko, P.E.4    Austin, P.C.5    Tu, J.V.6
  • 68
    • 61549124132 scopus 로고    scopus 로고
    • Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome
    • Ho PM, Maddox TM, Wang L, Fihn SD, Jesse RL, Peterson ED et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA. 2009;301:937-944
    • (2009) JAMA , vol.301 , pp. 937-944
    • Ho, P.M.1    Maddox, T.M.2    Wang, L.3    Fihn, S.D.4    Jesse, R.L.5    Peterson, E.D.6
  • 69
    • 70249139788 scopus 로고    scopus 로고
    • Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor:An analysis of two randomised trials
    • O'Donoghue ML, Braunwald E, Antman EM, Murphy SA, Bates ER, Rozenman Y et al. Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor:an analysis of two randomised trials. Lancet 2009;374:989-997
    • (2009) Lancet , vol.374 , pp. 989-997
    • O'Donoghue, M.L.1    Braunwald, E.2    Antman, E.M.3    Murphy, S.A.4    Bates, E.R.5    Rozenman, Y.6
  • 70
    • 77952359072 scopus 로고    scopus 로고
    • COGENT:A prospective, randomized, placebo-controlled trial of omeprazole in patients receiving aspirin and clopidogrel
    • Presented at: September 24, 2009;San Francisco, Calif
    • Bhatt DL. COGENT:A prospective, randomized, placebo-controlled trial of omeprazole in patients receiving aspirin and clopidogrel. Presented at:Transcatheter Cardiovascular Therapeutics; September 24, 2009;San Francisco, Calif.
    • Transcatheter Cardiovascular Therapeutics
    • Bhatt, D.L.1
  • 71
    • 70049098599 scopus 로고    scopus 로고
    • Comparison of omeprazole and pantoprazole influence on a high 150-mg clopidogrel maintenance dose:The PACA (Proton Pump Inhibitors and Clopidogrel Association) prospective randomized study
    • Cuisset T, Frere C, Quilici J, Poyet R, Gaborit B, Bali L et al. Comparison of omeprazole and pantoprazole influence on a high 150-mg clopidogrel maintenance dose:the PACA (Proton Pump Inhibitors and Clopidogrel Association) prospective randomized study. J Am Coll Cardiol 2009;54:1149-1153
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1149-1153
    • Cuisset, T.1    Frere, C.2    Quilici, J.3    Poyet, R.4    Gaborit, B.5    Bali, L.6
  • 72
    • 41249093357 scopus 로고    scopus 로고
    • Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance:A multicenter randomized prospective study
    • Bonello L, Camoin-Jau L, Arques S, Boyer C, Panagides D, Wittenberg O et al. Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance:a multicenter randomized prospective study. J Am Coll Cardiol 2008;51:1404-1411
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1404-1411
    • Bonello, L.1    Camoin-Jau, L.2    Arques, S.3    Boyer, C.4    Panagides, D.5    Wittenberg, O.6
  • 73
    • 57549099501 scopus 로고    scopus 로고
    • Glycoprotein IIb/IIIa inhibitors improve outcome after coronary stenting in clopidogrel nonresponders:A prospective, randomized study
    • Cuisset T, Frere C, Quilici J, Morange PE, Mouret JP, Bali L et al. Glycoprotein IIb/IIIa inhibitors improve outcome after coronary stenting in clopidogrel nonresponders:a prospective, randomized study. JACC Cardiovasc Interv 2008;1:649-653
    • (2008) JACC Cardiovasc Interv , vol.1 , pp. 649-653
    • Cuisset, T.1    Frere, C.2    Quilici, J.3    Morange, P.E.4    Mouret, J.P.5    Bali, L.6
  • 74
    • 67650745975 scopus 로고    scopus 로고
    • Intensifying platelet inhibition with tirofiban in poor responders to aspirin, clopidogrel, or both agents undergoing elective coronary intervention:Results from the double-blind, prospective, randomized Tailoring Treatment with Tirofiban in Patients Showing Resistance to Aspirin and/or Resistance to Clopidogrel study
    • Tailoring Treatment With Tirofiban in Patients Showing Resistance to Aspirin and/or Resistance to Clopidogrel (3T/2R) Investigators
    • Valgimigli M, Campo G, de Cesare N, Meliga E, Vranckx P, Furgieri A et al. Tailoring Treatment With Tirofiban in Patients Showing Resistance to Aspirin and/or Resistance to Clopidogrel (3T/2R) Investigators. Intensifying platelet inhibition with tirofiban in poor responders to aspirin, clopidogrel, or both agents undergoing elective coronary intervention:results from the double-blind, prospective, randomized Tailoring Treatment with Tirofiban in Patients Showing Resistance to Aspirin and/or Resistance to Clopidogrel study. Circulation 2009;119:3215-3222
    • (2009) Circulation , vol.119 , pp. 3215-3222
    • Valgimigli, M.1    Campo, G.2    De Cesare, N.3    Meliga, E.4    Vranckx, P.5    Furgieri, A.6
  • 75
    • 33747874088 scopus 로고    scopus 로고
    • A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes:The ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial
    • Montalescot G, Sideris G, Meuleman C, Bal-dit-Sollier C, Lellouche N, Steg PG et al. A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes:the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial. J Am Coll Cardiol 2006;48:931-938
    • (2006) J Am Coll Cardiol , vol.48 , pp. 931-938
    • Montalescot, G.1    Sideris, G.2    Meuleman, C.3    Bal-dit-Sollier, C.4    Lellouche, N.5    Steg, P.G.6
  • 76
    • 60649112469 scopus 로고    scopus 로고
    • Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38):Double-blind, randomised controlled trial
    • Montalescot G, Wiviott SD, Braunwald E, Murphy SA, Gibson CM, McCabe CH et al. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38):double-blind, randomised controlled trial. Lancet 2009;373:723-731
    • (2009) Lancet , vol.373 , pp. 723-731
    • Montalescot, G.1    Wiviott, S.D.2    Braunwald, E.3    Murphy, S.A.4    Gibson, C.M.5    McCabe, C.H.6
  • 77
    • 55949103494 scopus 로고    scopus 로고
    • Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-Thrombolysis in Myocardial Infarction 38
    • Wiviott SD, Braunwald E, Angiolillo DJ, Meisel S, Dalby AJ, Verheugt FW et al. Greater clinical benefit of more intensive oral antiplatelet therapy with prasugrel in patients with diabetes mellitus in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-Thrombolysis in Myocardial Infarction 38. Circulation 2008;118:1626-1636
    • (2008) Circulation , vol.118 , pp. 1626-1636
    • Wiviott, S.D.1    Braunwald, E.2    Angiolillo, D.J.3    Meisel, S.4    Dalby, A.J.5    Verheugt, F.W.6


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