메뉴 건너뛰기




Volumn 99, Issue 1, 2008, Pages 121-126

Assessment of ADP-induced platelet aggregation with light transmission aggregometry and multiple electrode platelet aggregometry before and after clopidogrel treatment

Author keywords

Clopidogrel; Platelet aggregation; Whole blood aggregometry

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

EID: 38349090725     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/th07-07-0478     Document Type: Article
Times cited : (273)

References (35)
  • 1
    • 33645052218 scopus 로고    scopus 로고
    • Smith SC, Jr., Feldman TE, Hirstifeld JW, Jr., et al. ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update 2001 Guidelines for Percutaneous Coronary Intervention). Circulation 2006; 113: el66-286.
    • Smith SC, Jr., Feldman TE, Hirstifeld JW, Jr., et al. ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update 2001 Guidelines for Percutaneous Coronary Intervention). Circulation 2006; 113: el66-286.
  • 2
    • 33645520354 scopus 로고    scopus 로고
    • Clopidogrel treatment prior to percutaneous coronary intervention: When enough isn't enough
    • Steinhubl SR, Charnigo R. Clopidogrel treatment prior to percutaneous coronary intervention: when enough isn't enough. JAMA 2006; 295: 1581-1582.
    • (2006) JAMA , vol.295 , pp. 1581-1582
    • Steinhubl, S.R.1    Charnigo, R.2
  • 3
    • 11844256436 scopus 로고    scopus 로고
    • Variability in platelet responsiveness to clopidogrel among 544 individuals
    • Serebruany VL, Steinhubl SR, Berger PB, et al. Variability in platelet responsiveness to clopidogrel among 544 individuals. J Am Coll Cardiol 2005; 45: 246-251.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 246-251
    • Serebruany, V.L.1    Steinhubl, S.R.2    Berger, P.B.3
  • 4
    • 34047096264 scopus 로고    scopus 로고
    • Variability in individual responsiveness to clopidogrel: Clinical implications, management, and future perspectives
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Variability in individual responsiveness to clopidogrel: clinical implications, management, and future perspectives. J Am Coll Cardiol 2007; 49: 1505-1516.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1505-1516
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3
  • 5
    • 33751572499 scopus 로고    scopus 로고
    • Clopidogrel response variability and future therapies: Clopidogrel: does one size fit all?
    • O'Donoghue M, Wiviott SD. Clopidogrel response variability and future therapies: clopidogrel: does one size fit all? Circulation 2006; 114: e600-606.
    • (2006) Circulation , vol.114
    • O'Donoghue, M.1    Wiviott, S.D.2
  • 6
    • 34250020766 scopus 로고    scopus 로고
    • Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis
    • Buonamici P, Marcucci R, Migliorini A, et al. Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis, J Am Coll Cardiol 2007; 49: 2312-2317.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2312-2317
    • Buonamici, P.1    Marcucci, R.2    Migliorini, A.3
  • 7
    • 33750479499 scopus 로고    scopus 로고
    • Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement
    • Hochholzer W, Trenk D, Bestehorn HP et al. Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement. J Am Coll Cardiol 2006; 48: 1742-1750.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1742-1750
    • Hochholzer, W.1    Trenk, D.2    Bestehorn, H.P.3
  • 8
    • 33749503499 scopus 로고    scopus 로고
    • Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation
    • Geisler T, Langer H, Wydymus M, et al. Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation. Eur Heart J 2006; 27: 2420-2425.
    • (2006) Eur Heart J , vol.27 , pp. 2420-2425
    • Geisler, T.1    Langer, H.2    Wydymus, M.3
  • 9
    • 18044362959 scopus 로고
    • Effect of adenosine diphosphate on the concentration of platelets in circulating blood
    • Born GV, Cross MJ. Effect of adenosine diphosphate on the concentration of platelets in circulating blood. Nature 1963; 197: 974-976.
    • (1963) Nature , vol.197 , pp. 974-976
    • Born, G.V.1    Cross, M.J.2
  • 10
    • 0032777493 scopus 로고    scopus 로고
    • Repeated-dose pharmacodynamics of clopidogrel in healthy subjects
    • Thebault JJ, Kieffer G, Lowe GD, et al. Repeated-dose pharmacodynamics of clopidogrel in healthy subjects. Semin Thromb Hemost 1999; 25 Suppl 2: 9-14.
    • (1999) Semin Thromb Hemost , vol.25 , Issue.SUPPL. 2 , pp. 9-14
    • Thebault, J.J.1    Kieffer, G.2    Lowe, G.D.3
  • 11
    • 0037454169 scopus 로고    scopus 로고
    • Aspirin resistance: A new independent predictor of vascular events?
    • Eikelboom JW, Hankey GJ. Aspirin resistance: a new independent predictor of vascular events? J Am Coll Cardiol 2003; 41: 966-968.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 966-968
    • Eikelboom, J.W.1    Hankey, G.J.2
  • 13
    • 33644499788 scopus 로고    scopus 로고
    • Determination of clopidogrel resistance by whole blood platelet aggregometry and inhibitors of the P2Y12 receptor
    • Ivandic BT, Schlick P, Staritz P, et al. Determination of clopidogrel resistance by whole blood platelet aggregometry and inhibitors of the P2Y12 receptor. Clin Chem 2006; 52: 383-388.
    • (2006) Clin Chem , vol.52 , pp. 383-388
    • Ivandic, B.T.1    Schlick, P.2    Staritz, P.3
  • 14
    • 33646441600 scopus 로고    scopus 로고
    • Correlation of a new point-of-care test with conventional optical aggregometry for the assessment of clopidogrel responsiveness
    • von Beckerath N, Pogatsa-Murray G, Wieczorek A, et al. Correlation of a new point-of-care test with conventional optical aggregometry for the assessment of clopidogrel responsiveness. Thromb Haemost 2006; 95: 910-911.
    • (2006) Thromb Haemost , vol.95 , pp. 910-911
    • von Beckerath, N.1    Pogatsa-Murray, G.2    Wieczorek, A.3
  • 15
    • 35548957533 scopus 로고    scopus 로고
    • Assessment of clopidogrel responsiveness: Measurements of maximum platelet aggregation, final platelet aggregation and their correlation with vasodilator-stimulated phosphoprotein in resistant patients
    • Gurbel PA, Bliden KP, Etherington A, et al. Assessment of clopidogrel responsiveness: Measurements of maximum platelet aggregation, final platelet aggregation and their correlation with vasodilator-stimulated phosphoprotein in resistant patients. Thromb Res 2007; 121: 107-115.
    • (2007) Thromb Res , vol.121 , pp. 107-115
    • Gurbel, P.A.1    Bliden, K.P.2    Etherington, A.3
  • 16
    • 33750083316 scopus 로고    scopus 로고
    • A head-to-head comparison between the VerifyNow P2Y 12 assay and light transmittance aggregometry for monitoring the individual platelet response to clopidogrel in patients undergoing elective percutaneous coronary intervention
    • van Werkum JW, van der Stelt CA, Seesing TH, et al. A head-to-head comparison between the VerifyNow P2Y 12 assay and light transmittance aggregometry for monitoring the individual platelet response to clopidogrel in patients undergoing elective percutaneous coronary intervention. J Thromb Haemost 2006; 4: 2516-2518.
    • (2006) J Thromb Haemost , vol.4 , pp. 2516-2518
    • van Werkum, J.W.1    van der Stelt, C.A.2    Seesing, T.H.3
  • 17
    • 33845366186 scopus 로고    scopus 로고
    • Comparison of VASP-phosphorylation assay to light-transmission aggregometry in assessing inhibition of the platelet ADP P2Y12 receptor
    • Pampuch A, Cerletti C, de Gaetano G. Comparison of VASP-phosphorylation assay to light-transmission aggregometry in assessing inhibition of the platelet ADP P2Y12 receptor. Thromb Haemost 2006; 96: 767-773.
    • (2006) Thromb Haemost , vol.96 , pp. 767-773
    • Pampuch, A.1    Cerletti, C.2    de Gaetano, G.3
  • 18
    • 33845358942 scopus 로고    scopus 로고
    • Multiple electrode aggregometry: A new device to measure platelet aggregation in whole blood
    • Toth O, Calatzis A, Penz S, et al. Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood. Thromb Haemost 2006; 96: 781-788.
    • (2006) Thromb Haemost , vol.96 , pp. 781-788
    • Toth, O.1    Calatzis, A.2    Penz, S.3
  • 19
    • 0018855854 scopus 로고
    • The electronic aggregometer: A novel device for assessing platelet behavior in blood
    • Cardinal DC, Flower RJ. The electronic aggregometer: a novel device for assessing platelet behavior in blood. J Pharmacol Methods 1980; 3: 135-158.
    • (1980) J Pharmacol Methods , vol.3 , pp. 135-158
    • Cardinal, D.C.1    Flower, R.J.2
  • 20
    • 34248400317 scopus 로고    scopus 로고
    • Variables influencing Multiplate(TM) whole blood impedance platelet aggregometry and turbidimetric platelet aggregation in healthy individuals
    • Seyfert UT, Haubelt H, Vogt A, et al. Variables influencing Multiplate(TM) whole blood impedance platelet aggregometry and turbidimetric platelet aggregation in healthy individuals. Platelets 2007; 18: 199 206.
    • (2007) Platelets , vol.18 , pp. 199-206
    • Seyfert, U.T.1    Haubelt, H.2    Vogt, A.3
  • 21
    • 33947322186 scopus 로고    scopus 로고
    • Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques
    • Penz SM, Reininger AJ, Toth O, et al. Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques. Thromb Haemost 2007; 97: 435-443.
    • (2007) Thromb Haemost , vol.97 , pp. 435-443
    • Penz, S.M.1    Reininger, A.J.2    Toth, O.3
  • 22
    • 36348990349 scopus 로고    scopus 로고
    • Mueller T, Dieplinger B, Poelz W, et al. Utility of whole blood impedance aggregometry for the assessment of clopidogrel action using the novel Multiplate(R) analyzer-comparison with two flow cytometric methods. Thromb Res 2007 [Epub ahead of print].
    • Mueller T, Dieplinger B, Poelz W, et al. Utility of whole blood impedance aggregometry for the assessment of clopidogrel action using the novel Multiplate(R) analyzer-comparison with two flow cytometric methods. Thromb Res 2007 [Epub ahead of print].
  • 23
    • 75649132996 scopus 로고    scopus 로고
    • Homepage Accessed May 12, 2007, at
    • Dynabyte Informationssysteme GmbH, Homepage (Accessed May 12, 2007, at www.multiplate.net).
    • Dynabyte Informationssysteme GmbH
  • 24
    • 27644465874 scopus 로고    scopus 로고
    • Clopidogrel effect on platelet reactivity in patients with stent thrombosis: Results of the CREST Study
    • Gurbel PA, Bliden KP, Samara W, et al. Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study J Am Coll Cardiol 2005; 46: 1827-1832.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1827-1832
    • Gurbel, P.A.1    Bliden, K.P.2    Samara, W.3
  • 25
    • 0038291914 scopus 로고    scopus 로고
    • Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement
    • Müller I, Besta F, Schulz C, et al. Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement. Thromb Haemost 2003; 89: 783-787.
    • (2003) Thromb Haemost , vol.89 , pp. 783-787
    • Müller, I.1    Besta, F.2    Schulz, C.3
  • 26
    • 0032777985 scopus 로고    scopus 로고
    • Single-dose pharmacodynamics of clopidogrel
    • Thebault JJ Kieffer G, Carion R. Single-dose pharmacodynamics of clopidogrel. Semin Thromb Hemost 1999; 25 Suppl 2: 3-8.
    • (1999) Semin Thromb Hemost , vol.25 , Issue.SUPPL. 2 , pp. 3-8
    • Thebault, J.J.1    Kieffer, G.2    Carion, R.3
  • 27
    • 9644281093 scopus 로고    scopus 로고
    • The difference between clopidogrel responsiveness and post-treatment platelet reactivity
    • Samara WM, Bliden KP, Tantry US, et al. The difference between clopidogrel responsiveness and post-treatment platelet reactivity. Thromb Res 2005; 115: 89-94.
    • (2005) Thromb Res , vol.115 , pp. 89-94
    • Samara, W.M.1    Bliden, K.P.2    Tantry, U.S.3
  • 28
    • 33845507441 scopus 로고    scopus 로고
    • Whole blood aggregometry for evaluation of the antiplatelet effects of clopidogrel
    • Hochholzer W, Trenk D, Frundi D, et al. Whole blood aggregometry for evaluation of the antiplatelet effects of clopidogrel. Thromb Res 2007; 119: 285-291.
    • (2007) Thromb Res , vol.119 , pp. 285-291
    • Hochholzer, W.1    Trenk, D.2    Frundi, D.3
  • 29
    • 0343487645 scopus 로고    scopus 로고
    • Influence of different anticoagulants on platelet aggregation in whole blood; a comparison between citrate, low molecular mass heparin and hirudin
    • Wallen NH, Ladjevardi M, Albert J, et al. Influence of different anticoagulants on platelet aggregation in whole blood; a comparison between citrate, low molecular mass heparin and hirudin. Thromb Res 1997; 87: 151-157.
    • (1997) Thromb Res , vol.87 , pp. 151-157
    • Wallen, N.H.1    Ladjevardi, M.2    Albert, J.3
  • 30
    • 23644437489 scopus 로고    scopus 로고
    • Matching the evaluation of the clinical efficacy of clopidogrel to platelet function tests relevant to the biological properties of the drug
    • Labarthe B, Theroux P, Angioi M, et al. Matching the evaluation of the clinical efficacy of clopidogrel to platelet function tests relevant to the biological properties of the drug. J Am Coll Cardiol 2005; 46: 63 8-645.
    • (2005) J Am Coll Cardiol , vol.46 , Issue.63 , pp. 8-645
    • Labarthe, B.1    Theroux, P.2    Angioi, M.3
  • 31
    • 0024471618 scopus 로고
    • Effect of the concentration of Ca2+ in the suspending medium on the responses of human and rabbit platelets to aggregating agents
    • Packham MA, Bryant NL, Guccione MA, et al. Effect of the concentration of Ca2+ in the suspending medium on the responses of human and rabbit platelets to aggregating agents. Thromb Haemost 1989; 62: 968-976.
    • (1989) Thromb Haemost , vol.62 , pp. 968-976
    • Packham, M.A.1    Bryant, N.L.2    Guccione, M.A.3
  • 32
    • 0023525650 scopus 로고
    • Thromboxane A2 causes feedback amplification involving extensive thromboxane A2 formation on close contact of human platelets in media with a low concentration of ionized calcium
    • Packham MA, Kinlough-Rathbone RL, Mustard JE Thromboxane A2 causes feedback amplification involving extensive thromboxane A2 formation on close contact of human platelets in media with a low concentration of ionized calcium. Blood 1987; 70: 647-651.
    • (1987) Blood , vol.70 , pp. 647-651
    • Packham, M.A.1    Kinlough-Rathbone, R.L.2    Mustard, J.E.3
  • 33
    • 0026353835 scopus 로고
    • ADP-induced second wave aggregation in platelet rich plasma from hypercholesterolemic rabbits
    • Weber A, Hohlfeld T, Schrör K. ADP-induced second wave aggregation in platelet rich plasma from hypercholesterolemic rabbits. Thromb Res 1991; 64: 703-712.
    • (1991) Thromb Res , vol.64 , pp. 703-712
    • Weber, A.1    Hohlfeld, T.2    Schrör, K.3
  • 34
    • 27644496060 scopus 로고    scopus 로고
    • Homepage Accessed September 15, 2007, at
    • Chyono-log Corporation, Homepage (Accessed September 15, 2007, at http://www.chronolog.com/disprb.htm).
    • Corporation
    • Chyono-log1
  • 35
    • 0034831048 scopus 로고    scopus 로고
    • Platelets, leukocytes, and coagulation
    • Bouchard BA, Tracy PB. Platelets, leukocytes, and coagulation. Curr Opin Hematol 2001; 8: 263 269.
    • (2001) Curr Opin Hematol , vol.8 , pp. 263-269
    • Bouchard, B.A.1    Tracy, P.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.