Cyclooxygenase-2 in human platelets as a possible factor in aspirin resistance

Lancet

Volumn 353, Issue 9156, 1999, Pages 900-901

  Weber, Artur Aron ^a   Zimmermann, Katja C ^a   Meyer Kirchrath, Jutta ^a   Schrör, Karsten ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIBODY; ANTICOAGULANT AGENT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOKINE; ENDOTOXIN; GROWTH FACTOR; MESSENGER RNA; PROSTAGLANDIN; THROMBOXANE A2;

ARTICLE; BLOOD FLOW; HEMOSTASIS; HUMAN; HUMAN CELL; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOCYTE; THROMBOSIS; WESTERN BLOTTING;

EID: 0345040152     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(99)00498-5     Document Type: Article

References (4)

1. Vane JR, Bakhle YS, Botting RM. Cyclooxygenases 1 and 2. Ann Rev Pharmacol Toxicol 1998; 38: 97-120.
2. Zimmermann KC, Sarbia M, Schrör K, Weber A-A. Constitutive cyclooxygenase-2 expression in healthy human and rabbit gastric mucosa. Mol Pharmacol 1998; 54: 536-40.
3. Schrör K. Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis. Sem Thromb Hemost 1998; 23: 349-56.
4. Helgason CM, Tortorice KL, Winkler SR, et al. Aspirin response and failure in cerebral infarction. Stroke 1993; 24: 345-50.