Autoimmune Diseases in Small Animals

Veterinary Clinics of North America - Small Animal Practice

Volumn 40, Issue 3, 2010, Pages 439-457

  Gershwin, Laurel J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antinuclear antibodies; Autoimmune disease; Autoimmune hemolytic anemia; Canine; Feline; Systemic lupus erythematosus

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINUCLEAR ANTIBODY; ANTIRHEUMATIC AGENT; ATROPINE; AZATHIOPRINE; CHLORAMBUCIL; CHOLINESTERASE INHIBITOR; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYCLOSPORIN A; DEXAMETHASONE; EDROPHONIUM CHLORIDE; ETANERCEPT; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR BLOCKING AGENT; LEVOTHYROXINE SODIUM; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; METHOTREXATE; METHYLPREDNISOLONE; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISONE; PROPYLTHIOURACIL; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBODY DETECTION; AUTOIMMUNE DISEASE; AUTOIMMUNE HEMOLYTIC ANEMIA; AUTOIMMUNE THROMBOCYTOPENIA; AUTOIMMUNE THYROIDITIS; AUTOIMMUNITY; BULLOUS SKIN DISEASE; CLINICAL TRIAL; COOMBS TEST; DIABETES MELLITUS; DIAGNOSTIC VALUE; DISCOID LUPUS ERYTHEMATOSUS; DRUG EFFICACY; DRUG MEGADOSE; DRUG RESPONSE; ERYTHROCYTE TRANSFUSION; GENETIC PREDISPOSITION; HUMAN; HYPERTHYROIDISM; INCIDENCE; MYASTHENIA GRAVIS; NEUTROPENIA; NONHUMAN; PATHOGENESIS; REVIEW; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; VETERINARY MEDICINE; VOGT KOYANAGI SYNDROME;

ANIMALS; AUTOIMMUNE DISEASES; CAT DISEASES; CATS; DOG DISEASES; DOGS; GENETIC PREDISPOSITION TO DISEASE; IMMUNE COMPLEX DISEASES; IMMUNOLOGIC DEFICIENCY SYNDROMES;

ANIMALIA; CANIS FAMILIARIS; FELIDAE;

EID: 77952783119     PISSN: 01955616     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cvsm.2010.02.003     Document Type: Review

References (70)

1. Figueroa-Vega N., Alfonso-Pérez M., Benedicto I., et al. Increased circulating pro-inflammatory cytokines and Th17 lymphocytes in Hashimoto's thyroiditis. J Clin Endocrinol Metab 2010, 95(2):953-962.
2. Afzali B., Lombardi G., Lechler R.I., et al. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol 2007, 148(1):32-46.
3. Gaffen S.L. The role of interleukin-17 in the pathogenesis of rheumatoid arthritis. Curr Rheumatol Rep 2009, 11(5):365-370.
4. Bertolaccini M.L., Hughes G.R.V., Khamashta M.A. Systemic lupus erythematosus. Diagnostic criteria in autoimmune diseases 2008, 3-8. Humana Press, New Jersey. Y. Shoenfeld, R. Cervera, M.E. Gershwin (Eds.).
5. Techner M., Krumbacher K., Doxiadis I., et al. Systemic lupus erythematosus in dogs: association to the major histocompatibility complex class I antigen DLA-A7. Clin Immunol Immunopathol 1990, 55:255-262.
6. Fournel C., Chabanne L., Caux C., et al. Canine systemic lupus erythematosus. I: a study of 75 cases. Lupus 1992, 1(3):133-139.
7. Monestier M., Novick K.E., Karam E.T., et al. Autoantibodies to histone, DNA, and nucleosome antigens in canine systemic lupus erythematousus. Clin Exp Immunol 1995, 99:37-41.
8. Smee N.M., Harkin K.R., Wilkerson M.J. Measurement of serum antinuclear antibody titer in dogs with and without systemic lupus erythematosus: 120 cases (1997-2005). J Am Vet Med Assoc 2007, 230(8):1180-1183.
9. Aucoin D.P., Rubin R.L., Peterson M.E., et al. Dose-dependent induction of anti-native DNA antibodies in cats by propylthiouracil. Arthritis Rheum 1988, 31(5):688-692.
10. Balch A., Mackin A. Canine immune-mediated hemolytic anemia: pathophysiology, clinical signs, and diagnosis. Compend Contin Educ Vet 2007, 29(4):217-225. [review].
11. Nelson R.W. Anemia. Small animal internal medicine 2003, 1162-1164. Mosby, St Louis (MO). 3rd edition. R.W. Nelson, C.G. Couto (Eds.).
12. Kohn B., Weingart C., Eckmann V., et al. Primary immune-mediated hemolytic anemia in 19 cats: diagnosis, therapy, and outcome (1998-2004). J Vet Intern Med 2006, 20(1):159-166.
13. Warman S.M., Murray J.K., Ridyard A., et al. Pattern of Coombs' test reactivity has diagnostic significance in dogs with immune-mediated haemolytic anaemia. J Small Anim Pract 2008, 49(10):525-530.
14. Kennedy L.J., Barnes A., Ollier W.E., et al. Association of a common dog leucocyte antigen class II haplotype with canine primary immune-mediated haemolytic anemia. Tissue Antigens 2006, 68(6):502-508.
15. Whelan M.F., O'Toole T.E., Chan D.L., et al. Use of human immunoglobulin in addition to glucocorticoids for the initial treatment of dogs with immune-mediated hemolytic anemia. J Vet Emerg CritCare (San Antonio) 2009, 19(2):158-164.
16. Goggs R., Boag A.K., Chan D.L. Concurrent immune-mediated haemolytic anaemia and severe thrombocytopenia in 21 dogs. Vet Rec 2008, 163(11):323-327.
17. Dircks B.H., Schuberth H.J., Mischke R. Underlying diseases and clinicopathologic variables of thrombocytopenic dogs with and without platelet-bound antibodies detected by use of a flow cytometric assay: 83 cases (2004-2006). J Am Vet Med Assoc 2009, 235(8):960-966.
18. Horgan J.E., Roberts B.K., Schermerhorn T. Splenectomy as an adjunctive treatment for dogs with immune-mediated hemolytic anemia: ten cases (2003-2006). J Vet Emerg Crit Care (San Antonio) 2009, 19(3):254-261.
19. Bianco D., Armstrong P.J., Washabau R.J. Treatment of severe immune-mediated thrombocytopenia with human IV immunoglobulin in 5 dogs. J Vet Intern Med 2007, 21(4):694-699.
20. Cortese L., Sica M., Piantedosi D., et al. Secondary immune-mediated thrombocytopenia in dogs naturally infected by Leishmania infantum. Vet Rec 2009, 164(25):778-782.
21. Vargo C.L., Taylor S.M., Haines D.M. Immune mediated neutropenia and thrombocytopenia in 3 giant schnauzers. Can Vet J 2007, 8(11):1159-1163.
22. Rocchi R., Rose N.R. Hashimoto thyroiditis. Diagnostic criteria in autoimmune diseases 2008, 217-220. Humana Press, New Jersey. Y. Shoenfeld, R. Cervera, M.E. Gershwin (Eds.).
23. Nelson R.W. Disorders of the thyroid gland. Small animal internal medicine 2003, 691-694. Mosby, St Louis (MO). 3rd edition. R.W. Nelson, C.G. Couto (Eds.).
24. Kennedy L.J., Quarmby S., Happ G.M., et al. Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele. Tissue Antigens 2006, 68(1):82-86.
25. Catchpole B., Kennedy L.J., Davison L.J., et al. Canine diabetes mellitus: from phenotype to genotype. J Small Anim Pract 2008, 49(1):4-10.
26. Ferm K., Björnerfeldt S., Karlsson A., et al. Prevalence of diagnostic characteristics indicating canine autoimmune lymphocytic thyroiditis in giant schnauzer and hovawart dogs. J Small Anim Pract 2009, 50(4):176-179.
27. Choi E.W., Shin I.S., Bhang D.H., et al. Hormonal change and cytokine mRNA expression in peripheral blood mononuclear cells during the development of canine autoimmune thyroiditis. Clin Exp Immunol 2006, 146(1):101-108.
28. Nelson R.W. Disorders of the endocrine pancreas. Small animal internal medicine 2003, 729-733. Mosby, St Louis (MO), 749-52. 3rd edition. R.W. Nelson, C.G. Couto (Eds.).
29. Hoenig M., Reusch C., Peterson M.E. Beta cell and insulin antibodies in treated and untreated diabetic cats. Vet Immunol Immunopathol 2000, 77(1-2):93-102.
30. Petersen J.S., Hejnaes K.R., Moody A., et al. Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radioligand assay. Diabetes 1994, 43(3):459-467.
31. Davison L.J., Weenink S.M., Christie M.R., et al. Autoantibodies to GAD65 and IA-2 in canine diabetes mellitus. Vet Immunol Immunopathol 2008, 126(1-2):83-90.
32. Medleau L., Hnilica K.A. Discoid lupus. Small animal dermatology 2006, 204. Saunders-Elsevier, St. Louis (MO). 2nd edition.
33. Medleau L., Hnilica K.A. Pemphigus foliaceous. Small animal dermatology 2006, 190. Saunders-Elsevier, St. Louis (MO). 2nd edition.
34. Medleau L., Hnilica K.A. Pemphigus vulgaris. Small animal dermatology 2006, 199. Saunders-Elsevier, St. Louis (MO). 2nd edition.
35. Medleau L., Hnilica K.A. Bullous pemphigoid. Small animal dermatology 2006, 202. Saunders-Elsevier, St. Louis (MO). 2nd edition.
36. Olivry T., Dunston S.M., Walker R.H., et al. Investigations on the nature and pathogenicity of circulating antikeratinocyte antibodies in dogs with pemphigus foliaceus. Vet Dermatol 2009, 20(1):42-50.
37. Nishifuji K., Olivry T., Ishii K., et al. IgG autoantibodies directed against desmoglein 3 cause dissociation of keratinocytes in canine pemphigus vulgaris and paraneoplastic pemphigus. Vet Immunol Immunopathol 2007, 117(3-4):209-221.
38. Nishifuji K., Yoshida-Yamakita K., Iwasaki T. A canine pemphigus foliaceus case showing parallel relationship of disease activity and titer of serum anti-keratinocyte cell surface antibodies. J Vet Med Sci 2005, 67(9):943-945.
39. Shelton G.D. Myasthenia gravis and disorders of neuromuscular transmission. Vet Clin North Am Small Anim Pract 2002, 32(1):189-206. [review], vii.
40. Couturier J., Huynh M., Boussarie D., et al. Autoimmune myasthenia gravis in a ferret. J Am Vet Med Assoc 2009, 235(12):1462-1466.
41. Shelton G.D., Schule A., Kass P.H. Risk factors for acquired myasthenia gravis in dogs: 1,154 cases (1991-1995). J Am Vet Med Assoc 1997, 211(11):1428-1431.
42. Uchida K., Awamura Y., Nakamura T., et al. Thymoma and multiple thymic cysts in a dog with acquired myasthenia gravis. J Vet Med Sci 2002, 64(7):637-640.
43. Wood S.L., Rosenstein D.S., Bebchuk T. Myasthenia gravis and thymoma in a dog. Vet Rec 2001, 148(18):573-574.
44. Day M.J. Review of thymic pathology in 30 cats and 36 dogs. J Small Anim Pract 1997, 38(9):393-403. [review].
45. Shelton G.D., Ho M., Kass P.H. Risk factors for acquired myasthenia gravis in cats: 105 cases (1986-1998). J Am Vet Med Assoc 2000, 216(1):55-57.
46. Nelson R.W. Disorders of peripheral nerves and the neuromuscular junction. Small Animal internal medicine 2003, 1059-1061. Mosby. 3rd edition. R.W. Nelson, C.G. Couto (Eds.).
47. Luo J., Lindstrom J. Antigenic structure of the human muscle nicotinic acetylcholine receptor main immunogenic region. J Mol Neurosci 2010, 40(1-2):217-220.
48. Heuser W. Canine rheumatoid arthritis. Can Vet J 1980, 21(11):314-316.
49. Lubberts E., van den Berg W.B. Potential of modulatory cytokines in the rheumatoid arthritis process. Drug News Perspect 2001, 14(9):517-522.
50. Moreland L.W. The role of cytokines in rheumatoid arthritis: inhibition of cytokines in therapeutic trials. Drugs Today (Barc) 1999, 35(4-5):309-319.
51. Jazayeri J.A., Carroll G.J., Vernallis A.B. Interleukin-6 subfamily cytokines and rheumatoid arthritis: role of antagonists. Int Immunopharmacol 2010, 10(1):1-8.
52. Hegemann N., Wondimu A., Ullrich K., et al. Synovial MMP-3 and TIMP-1 levels and their correlation with cytokine expression in canine rheumatoid arthritis. Vet Immunol Immunopathol 2003, 91(3-4):199-204.
53. Ollier W.E., Kennedy L.J., Thomson W., et al. Dog MHC alleles containing the human RA shared epitope confer susceptibility to canine rheumatoid arthritis. Immunogenetics 2001, 53(8):669-673.
54. May C., Carter S.D., Bell S.C., et al. Immune responses to canine distemper virus in joint diseases of dogs. Br J Rheumatol 1994, 33(1):27-31.
55. Bell S.C., Carter S.D., Bennett D. Canine distemper viral antigens and antibodies in dogs with rheumatoid arthritis. Res Vet Sci 1991, 50(1):64-68.
56. Roush J.K., Manley P.A., Dueland R.T. Rheumatoid arthritis subsequent to Borrelia burgdorferi infection in two dogs. J Am Vet Med Assoc 1989, 195(7):951-953.
57. Angles J.M., Famula T.R., Pedersen N.C. Uveodermatologic (VKH-like) syndrome in American Akita dogs is associated with an increased frequency of DQA1*00201. Tissue Antigens 2005, 66(6):656-665.
58. Medleau L., Hnilica K.A. Canine uveodermatologic syndrome (Vogt-Koyangi-Harada-like syndrome, VKH). Small animal dermatology 2006, 292. Saunders-Elsevier, St. Louis (MO). 2nd edition.
59. Yamaki K., Ohono S. Animal models of Vogt-Koyanagi-Harada disease (sympathetic ophthalmia). Ophthalmic Res 2008, 40(3-4):129-135.
60. Hansson-Hamlin H., Lilliehöök I., Trowald-Wigh G. Subgroups of canine antinuclear antibodies in relation to laboratory and clinical findings in immune-mediated disease. Vet Clin Pathol 2006, 35(4):397-404.
61. Ginel P.J., Camacho S., Lucena R. Anti-histone antibodies in dogs with leishmaniasis and glomerulonephritis. Res Vet Sci 2008, 85(3):510-514.
62. Smith B.E., Tompkins M.B., Breitschwerdt E.B. Antinuclear antibodies can be detected in dog sera reactive to Bartonella vinsonii subsp. berkhoffii, Ehrlichia canis, or Leishmania infantum antigens. J Vet Intern Med 2004, 18(1):47-51.
63. Conrad K., Ittenson A., Reinhold D., et al. High sensitive detection of double-stranded DNA autoantibodies by a modified Crithidia luciliae immunofluorescence test. Ann N Y Acad Sci 2009, 1173:180-185.
64. Welin Henriksson E., Hansson H., Karlsson-Parra A., et al. Autoantibody profiles in canine ANA-positive sera investigated by immunoblot and ELISA. Vet Immunol Immunopathol 1998, 61(2-4):157-170. [review].
65. Hansson H., Karlsson-Parra A. Canine antinuclear antibodies: comparison of immunofluorescence staining patterns and precipitin reactivity. Acta Vet Scand 1999, 40(3):205-212.
66. Hansson-Hamlin H., Rönnelid J. Detection of antinuclear antibodies by the Inno-Lia ANA update test in canine systemic rheumatic disease. Vet Clin Pathol 2009, [Epub ahead of print].
67. Warman S.M., Murray J.K., Ridyard A., et al. Pattern of Coombs' test reactivity has diagnostic significance in dogs with immune-mediated haemolytic anaemia. J Small Anim Pract 2008, 49(10):525-530.
68. Aucoin D.P., Peterson M.E., Hurvitz A.I., et al. Propylthiouracil-induced immune-mediated disease in the cat. J Pharmacol Exp Ther 1985, 234(1):13-18.
69. Aucoin D.P., Rubin R.L., Peterson M.E., et al. Dose-dependent induction of anti-native DNA antibodies in cats by propylthiouracil. Arthritis Rheum 1988, 31(5):688-692.
70. Nelson R.W. Immunosuppressive drugs. Small animal internal medicine 2003, 1216-1219. Mosby, St Louis (MO). 3rd edition. R.W. Nelson, C.G. Couto (Eds.).