Primary immune-mediated hemolytic anemia in 19 cats: Diagnosis, therapy, and outcome (1998-2004)

Journal of Veterinary Internal Medicine

Volumn 20, Issue 1, 2006, Pages 159-166

  Kohn, Barbara ^a   Weingart, Christiane ^a   Eckmann, Vera ^a   Ottenjann, Mareike ^a   Leibold, Wolfgang ^b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Coombs' test; Course of disease; Feline hemolytic anemia; Osmotic fragility of red blood cells; Persistent erythrocyte agglutination; Primary and secondary immune mediated hemolysis

Indexed keywords

ANTIINFECTIVE AGENT; HISTAMINE H2 RECEPTOR ANTAGONIST; IMMUNOSUPPRESSIVE AGENT; PREDNISOLONE;

ANIMAL; ANIMAL DISEASE; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; BLOOD TRANSFUSION; CAT; CAT DISEASE; FEMALE; IMMUNOLOGY; MALE; PATHOLOGY; TREATMENT OUTCOME;

ANEMIA, HEMOLYTIC, AUTOIMMUNE; ANIMALS; ANTI-BACTERIAL AGENTS; BLOOD TRANSFUSION; CAT DISEASES; CATS; FEMALE; HISTAMINE H2 ANTAGONISTS; IMMUNOSUPPRESSIVE AGENTS; MALE; PREDNISOLONE; TREATMENT OUTCOME;

CANIS FAMILIARIS; FELIDAE; FELINE LEUKEMIA VIRUS;

EID: 32344448290     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2006)20[159:PIHAIC]2.0.CO;2     Document Type: Article

References (31)

1. Werner LL, Gorman NT. Immune-mediated disorders of cats. Vet Clin North Am Small Anim Pract 1984;14:1039-1064.
2. Kohn B. Erythrozytenstudien bei gesunden und anämischen Katzen. Habilitationsschrift, 2001, Free University of Berlin.
3. Scott DW, Schultz RD, Post JE, et al. Autoimmune hemolytic anemia in the cat. J Am Anim Hosp Assoc 1973;9:530-539.
4. Maede Y, Hata R. Studies of feline haemobartonellosis. II. The mechanism of anemia produced by infection with Haemobartonella felis. Jap J Vet Sci 1975;37:49-54.
5. Peterson ME, Hutwitz AI, Leib MS, et al. Propylthiouracil-associated hemolytic anemia, thrombocytopenia, and antinuclear antibodies in cats with hyperthyroidism. J Am Vet Med Assoc 1984;184:806-808.
6. Lusson D, Billiemaz B, Chabanne JL. Circulating lupus anticoagulant and probable systemic lupus erythematosus in a cat. J Feline Med Surg 1999;3:193-196.
7. Auer L, Bell K. Transfusion reactions in cats due to AB-blood group incompatibility. Res Vet Sci 1983;35:145-152.
8. Klag AR, Giger U, Shofer FS. Idiopathic immune-mediated hemolytic anemia in dogs: 42 cases (1986-1990). J Am Vet Med Assoc 1993;202:783-788.
9. Slappendel RJ. The diagnostic significance of the direct antiglobulin test (DAT) in anemic dogs. J Vet Immunol Immunopathol 1979;1:49-60.
10. Engelbrecht R, Kohn B, Leibold W, Giger U. Klinische Befunde, Diagnostik und Behandlungserfolge bei der primären und sekundären immunhämolytischen Anämie beim Hund. Kleintierpraxis, 2002;47:265-278.
11. Dunn JK, Searcy GP, Hirsch VM. The diagnostic significance of a positive direct antiglobulin test in anemic cats. Can J Comp Med 1984;48:349-353.
12. Giger U. Regenerative anemias caused by blood loss or hemolysis. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine. Philadelphia, PA: WB Saunders; 2000:1784-1804.
13. Jain NC. Osmotic fragility of erythrocytes in dogs and cats in health and in certain hematologic disorders. Cornell Vet 1973;63:411-423.
14. Slappendel RJ. Hemolytic Anemia in the Dog. University of Utrecht: Proefschrift, 1978.
15. Kohn B, Goldschmidt HM, Hohenhaus AE, Giger U. Anemia, splenomegaly, and increased osmotic fragility of erythrocytes in Abyssinian and Somali cats. J Am Vet Med Assoc 2000;217:1483-1491.
16. Beutler E. Osmotic fragility. In: Williams JW, Beutler E, Erslev AJ, Lichtman MA, eds. Hematology. New York, NY: McGraw Hill; 1990:1726-1728.
17. Lutz H. Virusinfektionen. In: Horzinek MC, Schmidt V, Lutz H, eds. Krankheiten der Katze. Stuttgart: Enke Verlag; 2003:119-123.
18. Griot-Wenk ME, Giger U. Feline transfusion medicine. Blood types and their clinical importance. Vet Clin North Am Small Anim Pract 1995;25:1305-1322.
19. Weingart C, Giger U, Kohn B. Whole blood transfusions in 91 cats: A clinical evaluation. J Feline Med Surg 2004;6:139-148.
20. Hübner J, Kühnlein P, Müller E. Diagnose von Haemobartonella felis-Infektionen bei der Katze. Kleintierpraxis 2002;47:341-345.
21. Person JM, Sicard M, Pellerin JL. Les anemies hemolytiques auto-immunes chez le chat: Etude clinique et immunopathologique de cinq cas. Revue Med Vet 1997;148:107-114.
22. Duval D, Giger U. Vaccine-associated immune-mediated hemolytic anemia in the dog. J Vet Intern Med 1996;10:290-295.
23. Kohn B, Garner M, Lübke S, et al. Polyarthritis following vaccination in four dogs. Vet Comp Orthop Traumatol 2003;16:6-10.
24. Dawson S, McArdle F, Bennett D, et al. Investigation of vaccine reactions and breakdowns after feline caicivirus vaccination. Vet Rec 1993;132:346-350.
25. Stokol T, Blue JT. Pure red cell aplasia in cats: 9 cases (1989-1997). J Am Vet Med Assoc 1999;214:75-79.
26. Scott-Moncrieff JC, Treadwell NG, Mc Cullough SM, Brooks MB. Hemostatic abnormalities in dogs with primary immune-mediated hemolytic anemia. J Am Anim Hosp Assoc 2001;37:220-227.
27. Mc Manus PM, Linden EC. Correlation between leukocytosis and necropsy findings in dogs with immune-mediated hemolytic anemia: 34 cases (1994-1999). J Am Vet Med Assoc 2001;218:1308-1313.
28. Couto CG. A diagnostic approach to splenomegaly in cats and dogs. Vet Med 1990;3:220-238.
29. Holmes R. The occurrence of blood groups in cats. J Exp Biol 1953;30:350-357.
30. Tizard IR. Veterinary Immunology. Philadelphia, PA: WB Saunders; 2000:379-381.
31. Reimer ME, Troy GS, Warnick LD. Immune-mediated hemolytic anemia: 70 cases (1988-1996). J Am Anim Hosp Assoc 1999;35:384-391.