메뉴 건너뛰기




Volumn 77, Issue 6, 2010, Pages 524-533

The checkpoint kinase ATM protects against stress-induced elevation of cyclin D1 and potential cell death in neurons

Author keywords

Ataxia telangiectasia; ATM; Cell cycle; Cyclin D1; Neural stem cell; Neurodegeneration; Neuron; Reactive oxygen

Indexed keywords

ATM PROTEIN; CELL CYCLE PROTEIN; CYCLIN D1; DNA BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

EID: 77952722363     PISSN: 15524922     EISSN: 15524930     Source Type: Journal    
DOI: 10.1002/cyto.a.20885     Document Type: Article
Times cited : (13)

References (37)
  • 1
    • 4444339751 scopus 로고    scopus 로고
    • ATM and ataxia telangiectasia
    • McKinnon PJ. ATM and ataxia telangiectasia. EMBO Rep 2004;5:772-776.
    • (2004) EMBO Rep , vol.5 , pp. 772-776
    • McKinnon, P.J.1
  • 2
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham RT. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 2001;15:2177-2196.
    • (2001) Genes Dev , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 3
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003;421:499-506.
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 5
    • 33745823159 scopus 로고    scopus 로고
    • The ATM-mediated DNA-damage response: Taking shape
    • Shiloh Y. The ATM-mediated DNA-damage response: Taking shape. Trends Biochem Sci 2006;31:402-410.
    • (2006) Trends Biochem Sci , vol.31 , pp. 402-410
    • Shiloh, Y.1
  • 6
    • 34247483506 scopus 로고    scopus 로고
    • ATM activation and DNA damage response
    • Lavin MF, Kozlov S. ATM activation and DNA damage response. Cell Cycle 2007;6:931-942.
    • (2007) Cell Cycle , vol.6 , pp. 931-942
    • Lavin, M.F.1    Kozlov, S.2
  • 8
    • 0028827312 scopus 로고
    • The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species
    • Savitsky K, Sfez S, Tagle DA, Ziv Y, Sartiel A, Collins FS, Shiloh Y, Rotman G. The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum Mol Genet 1995;4:2025-2032.
    • (1995) Hum Mol Genet , vol.4 , pp. 2025-2032
    • Savitsky, K.1    Sfez, S.2    Tagle, D.A.3    Ziv, Y.4    Sartiel, A.5    Collins, F.S.6    Shiloh, Y.7    Rotman, G.8
  • 9
    • 33746164726 scopus 로고    scopus 로고
    • Spinocerebellar ataxia with ocular motor apraxia and DNA repair
    • Onodera O. Spinocerebellar ataxia with ocular motor apraxia and DNA repair. Neuropathology 2006;26:361-367.
    • (2006) Neuropathology , vol.26 , pp. 361-367
    • Onodera, O.1
  • 10
    • 33749678963 scopus 로고    scopus 로고
    • Ataxia-telangiectasia and related diseases
    • Frappart PO, McKinnon PJ. Ataxia-telangiectasia and related diseases. Neuromolecular Med 2006;8:495-511.
    • (2006) Neuromolecular Med , vol.8 , pp. 495-511
    • Frappart, P.O.1    McKinnon, P.J.2
  • 11
    • 44949238447 scopus 로고    scopus 로고
    • The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle
    • Biton S, Barzilai A, Shiloh Y. The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle. DNA Repair (Amst) 2008;7:1028-1038.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1028-1038
    • Biton, S.1    Barzilai, A.2    Shiloh, Y.3
  • 12
    • 0030062245 scopus 로고    scopus 로고
    • Mitotic mechanisms in Alzheimer's disease?
    • Vincent I, Rosado M, Davies P. Mitotic mechanisms in Alzheimer's disease? J Cell Biol 1996;132:413-425.
    • (1996) J Cell Biol , vol.132 , pp. 413-425
    • Vincent, I.1    Rosado, M.2    Davies, P.3
  • 13
    • 0030921323 scopus 로고    scopus 로고
    • Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease
    • McShea A, Harris PL, Webster KR, Wahl AF, Smith MA. Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease. Am J Pathol 1997;150:1933-1939.
    • (1997) Am J Pathol , vol.150 , pp. 1933-1939
    • McShea, A.1    Harris, P.L.2    Webster, K.R.3    Wahl, A.F.4    Smith, M.A.5
  • 14
    • 33644650035 scopus 로고    scopus 로고
    • Cell-cycle markers in a transgenic mouse model of human tauopathy: Increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1
    • Delobel P, Lavenir I, Ghetti B, Holzer M, Goedert M. Cell-cycle markers in a transgenic mouse model of human tauopathy: Increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. Am J Pathol 2006;168:878-887.
    • (2006) Am J Pathol , vol.168 , pp. 878-887
    • Delobel, P.1    Lavenir, I.2    Ghetti, B.3    Holzer, M.4    Goedert, M.5
  • 15
    • 0030454478 scopus 로고    scopus 로고
    • Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimer's disease
    • Arendt T, Rodel L, Gartner U, Holzer M. Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimer's disease. Neuroreport 1996;7:3047-3049.
    • (1996) Neuroreport , vol.7 , pp. 3047-3049
    • Arendt, T.1    Rodel, L.2    Gartner, U.3    Holzer, M.4
  • 18
    • 0030031514 scopus 로고    scopus 로고
    • Cyclin D1 is an essential mediator of apoptotic neuronal cell death
    • Kranenburg O, van der Eb AJ, Zantema A. Cyclin D1 is an essential mediator of apoptotic neuronal cell death. Embo J 1996;15:46-54.
    • (1996) Embo J , vol.15 , pp. 46-54
    • Kranenburg, O.1    Van Der Eb, A.J.2    Zantema, A.3
  • 19
    • 0035882278 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo
    • Ino H, Chiba T. Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo. J Neurosci 2001;21:6086-6094.
    • (2001) J Neurosci , vol.21 , pp. 6086-6094
    • Ino, H.1    Chiba, T.2
  • 20
    • 47149109415 scopus 로고    scopus 로고
    • Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity
    • Koeller HB, Ross ME, Glickstein SB. Cyclin D1 in excitatory neurons of the adult brain enhances kainate-induced neurotoxicity. Neurobiol Dis 2008;31:230-241.
    • (2008) Neurobiol Dis , vol.31 , pp. 230-241
    • Koeller, H.B.1    Ross, M.E.2    Glickstein, S.B.3
  • 21
    • 0028129498 scopus 로고
    • Cycling D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblassts
    • Pagano M, Theodoras AM, Tam SW, Draetta GF. Cycling D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblassts. Genes Dev 1994;8:1627-1639.
    • (1994) Genes Dev , vol.8 , pp. 1627-1639
    • Pagano, M.1    Theodoras, A.M.2    Tam, S.W.3    Draetta, G.F.4
  • 22
    • 17844382743 scopus 로고    scopus 로고
    • Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis
    • Guo Y, Yang K, Harwalkar J, Nye JM, Mason DR, Garrett MD, Hitomi M, Stacey DW. Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis. Oncogene 2005;24:2599-2612.
    • (2005) Oncogene , vol.24 , pp. 2599-2612
    • Guo, Y.1    Yang, K.2    Harwalkar, J.3    Nye, J.M.4    Mason, D.R.5    Garrett, M.D.6    Hitomi, M.7    Stacey, D.W.8
  • 23
    • 13944249549 scopus 로고    scopus 로고
    • Destabilization of cyclin D1 message plays a critical role in cell cycle exit upon mitogen withdrawal
    • Guo Y, Harwalkar J, Stacey DW, Hitomi M. Destabilization of cyclin D1 message plays a critical role in cell cycle exit upon mitogen withdrawal. Oncogene 2005;24:1032-1042.
    • (2005) Oncogene , vol.24 , pp. 1032-1042
    • Guo, Y.1    Harwalkar, J.2    Stacey, D.W.3    Hitomi, M.4
  • 24
    • 0033533724 scopus 로고    scopus 로고
    • Cyclin D1 production in cycling cells depends on Ras in a cell-cycle-specific manner
    • DOI 10.1016/S0960-9822(99)80476-X
    • Hitomi M, Stacey DW. Cyclin D1 production in cycling cells depends on ras in a cellcycle-specific manner. Curr Biol 1999;9:1075-1084. (Pubitemid 29504477)
    • (1999) Current Biology , vol.9 , Issue.19 , pp. 1075-1084
    • Hitomi, M.1    Stacey, D.W.2
  • 25
    • 0032999249 scopus 로고    scopus 로고
    • Cellular ras and cyclin D1 are required during different cell cycle periods in cycling NIH 3T3 cells
    • Hitomi M, Stacey DW. Cellular ras and cyclin D1 are required during different cell cycle periods in cycling NIH 3T3 cells. Mol Cell Biol 1999;19:4623-4632.
    • (1999) Mol Cell Biol , vol.19 , pp. 4623-4632
    • Hitomi, M.1    Stacey, D.W.2
  • 26
    • 0035895663 scopus 로고    scopus 로고
    • Ras-dependent cell cycle commitment during G2 phase
    • Hitomi M, Stacey DW. Ras-dependent cell cycle commitment during G2 phase. FEBS Lett 2001;490:123-131.
    • (2001) FEBS Lett , vol.490 , pp. 123-131
    • Hitomi, M.1    Stacey, D.W.2
  • 27
    • 0037376168 scopus 로고    scopus 로고
    • Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells
    • Stacey DW. Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells. Curr Opin Cell Biol 2003;15:158-163.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 158-163
    • Stacey, D.W.1
  • 29
    • 34247167103 scopus 로고    scopus 로고
    • Variations in cyclin D1 levels through the cell cycle determine the proliferative fate of a cell
    • Yang K, Hitomi M, Stacey DW. Variations in cyclin D1 levels through the cell cycle determine the proliferative fate of a cell. Cell Div 2006;1:32-40.
    • (2006) Cell Div , vol.1 , pp. 32-40
    • Yang, K.1    Hitomi, M.2    Stacey, D.W.3
  • 30
    • 33749599776 scopus 로고    scopus 로고
    • Evidence that the ATR/Chk1 pathway maintains normal replication fork progression during unperturbed S phase
    • Petermann E, Caldecot KW. Evidence that the ATR/Chk1 pathway maintains normal replication fork progression during unperturbed S phase. Cell Cycle 2006;5:2203-2209.
    • (2006) Cell Cycle , vol.5 , pp. 2203-2209
    • Petermann, E.1    Caldecot, K.W.2
  • 31
    • 50249184808 scopus 로고    scopus 로고
    • Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression
    • Hitomi M, Yang K, Stacey AW, Stacey DW. Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression. Mol Cell Biol 2008;28:5478-5493.
    • (2008) Mol Cell Biol , vol.28 , pp. 5478-5493
    • Hitomi, M.1    Yang, K.2    Stacey, A.W.3    Stacey, D.W.4
  • 33
    • 42049086285 scopus 로고    scopus 로고
    • Hitomi M Cell cycle studies based upon quantitative image analysis
    • Stacey DW, Hitomi M Cell cycle studies based upon quantitative image analysis. Cytometry A 2008;73A:270-278.
    • (2008) Cytometry A , vol.73 A , pp. 270-278
    • Stacey, D.W.1
  • 34
    • 14944346310 scopus 로고    scopus 로고
    • Loss of neuronal cell cycle control in ataxia-telangiectasia: A unified disease mechanism
    • Yang Y, Herrup K. Loss of neuronal cell cycle control in ataxia-telangiectasia: A unified disease mechanism. J Neurosci 2005;25:2599-12529
    • (2005) J Neurosci , vol.25 , pp. 2599-12529
    • Yang, Y.1    Herrup, K.2
  • 35
    • 44949085340 scopus 로고    scopus 로고
    • The role of the DNA damage response in neuronal development, organization and maintenance
    • Barzilai A, Biton S, Shiloh Y. The role of the DNA damage response in neuronal development, organization and maintenance. DNA Repair (Amst) 2008;7:1010-1027.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1010-1027
    • Barzilai, A.1    Biton, S.2    Shiloh, Y.3
  • 36
    • 3242886115 scopus 로고    scopus 로고
    • DNA damage responses to oxidative stress
    • Barzilai A, Yamamoto. K. DNA damage responses to oxidative stress. DNA Repair (Amst) 2004;3:1109-1115.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1109-1115
    • Barzilai, A.1    Yamamoto, K.2
  • 37
    • 72849109858 scopus 로고    scopus 로고
    • NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease
    • Varvel NH, Bhaskar K, Kounnas MZ, Wagner SL, Yang Y, Lamb BT, Herrup K. NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease. J Clin Invest 2009;119:3692-3702.
    • (2009) J Clin Invest , vol.119 , pp. 3692-3702
    • Varvel, N.H.1    Bhaskar, K.2    Kounnas, M.Z.3    Wagner, S.L.4    Yang, Y.5    Lamb, B.T.6    Herrup, K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.