Cellular Ras and cyclin D1 are required during different cell cycle periods in cycling NIH 3T3 cells

Molecular and Cellular Biology

Volumn 19, Issue 7, 1999, Pages 4623-4632

  Hitomi, Masahiro ^a   Stacey, Dennis W ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; RAS PROTEIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN 3T3; DNA SYNTHESIS; MICROINJECTION; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0032999249     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.7.4623     Document Type: Article

References (44)

1. Albanese, C., J. Johnson, G. Watanabe, N. Eklund, D. Vu, A Arnold, and R. G. Pestell. 1995. Transforming p21ras mutants and c-ETS-2 activate the cyclin D1 promoter through distinguishable regions. J. Biol. Chem. 270: 23589-23597.
2. Choi, Y. H., S. J. Lee, P. Nguyen, J. S. Jang, J. Lee, M-L. Wu, E. Takano, M. Maki, P. A. Henkart, and J. B. Trepel. 1997. Regulation of cyclin D1 by calpain protease. J. Biol. Chem. 272:28479-28484.
3. Coats, S., M. Flanagan, J. Nourse, and J. M. Roberts. 1996. Requirement of p27kip1 for restriction point control of the fibroblast cell cycle. Science 272:877-880.
4. Diehl, J. A., M. Cheng, F. M. Roussel, and C. J. Sherr. 1998. Glycogen synthase kinase-3heta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 12:3499-3511.
5. 1 phase in BALB/c 3T3 cells. Mol. Cell. Biol. 14:5441-5449.
6. Filmus, J., A. I. Robles, W. Shi, M. J. Wong, L. L. Colombo, and C. J. Conti. 1994. Induction of cyclin D1 overexpression by activated ras. Oncogene 9:3627-3633.
7. Fox, P. L., G. Sa, S. F. Dobrowolski, and D. W. Stacey. 1994. The regulation of endothelial cell motility by p21 ras. Oncogene 93519-3526.
8. German, C., R. H. Skinner, J. V. Skelly, S. Neidle, and P. N. Lowe. 1996. Equilibrium and kinetic measurements reveal rapidly reversible binding of Ras to Raf. J. Biol. Chem. 271:6713-6719.
9. Hattori, S., D. J. Clanton, T. Satoh, S. Nakamura, Y. Kaziro, M. Kawakila, and T. Y. Shih. 1987. Neutralizing monoclonal antibody against ras oncogene product p21 which impairs guanine nucleotide exchange. Mol. Cell. Biol. 7:1999-2002.
10. Herrmann, C., G. A. Martin, and A. Wittinghofer. 1995. Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase. J. Biol. Chem. 270:2901-2905.
11. Hitomi, M., J. Shu, D. Strom, S. W. Hiebert, L. M. Harter, and D. W. Stacey. 1996. Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation. J. Biol. Chem. 271:9375-9383.
12. 1S-phase growth arrest. Mol. Cell. Biol. 11:1185-1194.
13. Hurn, B. A. L., and S. M. Chantler. 1980. Production of reagent antibodies. Methods Enzymol. 70:104-142.
14. 1 transition and during exponential growth in mouse fibroblasts: differential role of Fos proteins. Mol. Cell. Biol. 12:5015-5023.
15. Larsson, O., A. Zetterberg, and W. Engstrom. 1985. Consequences of parental exposure to serum-free medium for progeny cell division. J. Cell Sci. 75:259-268.
16. 1 progression in NIH 3T3 cells. Mol. Cell. Biol. 15:3654-3663.
17. 1 control in retinoblastoma gene-deficient cells independently of cdk4 activity. Mol. Cell. Biol. 15:2600-2611.
18. Lukas, J., M. Pagano, Z. Staskova, G. Draetta, and J. Bartek. 1994. Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumor cell lines. Oncogene 9:707-718.
19. Mayol, X., J. Garriga, and X. Grana. 1996. G1 cyclin/CDK-independent phosphorylation and accumulation of p130 during the transition from G1 to G0 lead to its association with E2F-4. Oncogene 13:237-246.
20. Moodie, S. A., and A. Wolfman. 1994. The 3Rs of life: ras raf and growth regulation. Trends Genet. 10:44-48.
21. Mulcahy, L. S., M. R. Smith, and D. W. Stacey. 1985. Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells. Nature 313:241-243.
22. Nevtns, J. R. 1992. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 258:424-429.
23. 1-to-S phase transition. Mol. Cell. Biol. 15:2612-2624.
24. O'Keefe, E. J., and W. J. Pledger. 1983. A model of cell cycle control: sequential events regulated by growth factors. Mol. Cell. Endocrinol. 31:167-186.
25. Pardee, A. B. 1974. A restriction point for control of normal animal cell proliferation. Proc. Natl. Acad. Sci. USA 71:1286-1290.
26. Pardee, A. B. 1989. G1 events and regulation of cell proliferation. Science 246:603-608.
27. Peeper, D. S., T. M. Upton, M. H. Ladha, E. Neuman, J. Zalvide, R. Bernard, J. A. DeCaprio, and M. E. Ewen. 1997. Ras signaling linked to the cell-cycle machinery by the retinoblastoma protein. Nature 386:177-181.
28. Rodriguez-Viciana, P., P. H. Warne, R. Dhand, R Vanhaesebroeck, I. Gout, M. J. Fry, M. D. Waterfleld, and J. Downward. 1994. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370:527-534.
29. Rossow, P. W., V. G. H. Riddle, and A. B. Pardee. 1979. Synthesis of labile, serum-dependent protein in early G1 controls animal cell growth. Proc. Natl. Acad. Sci. USA 76:4446-4450.
30. Schlessinger, J. 1993. How receptor tyrosine kinases activate ras. Trends Biochem. Sci. 18:273-275.
31. Sherr, C. J. 1995. D-type cyclins. Trends Biochem. Sci. 20:187-190.
32. Sherr, C. J., and J. M. Roberts. 1995. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9:1149-1163.
33. Shu, J., M. Hitomi, and D. W. Stacey. 1996. Activation of JNK/SAPK pathway is not directly inhibitory for cell cycle progression in NIH3T3 cells. Oncogene 13:2421-2430.
34. 1 cell state. Mol. Cell. Biol. 16:6965-6976.
35. Smith, M. R., S. J. DeGudicibus, and D. W. Stacey. 1986. Requirement for c-ras proteins during viral oncogene transformation. Nature 320:540-543.
36. Stacey, D., T. Watson, H. Kung, and T. Curran. 1987. Microinjection of transforming Ras protein induces c-fos expression. Mol. Cell. Biol. 7:523-527.
37. Stacey, D. W. 1981. Microinjection of mRNA and other macromolecules into living cells. Methods Enzymol. 79:76-88.
38. Taylor, S. J., and D. Shalloway. 1996. Cell cycle-dependent activation of Ras. Curr. Biol. 6:1621-1627.
39. van Weering, D., J. de Rooij, B. Marte, J. Downward, J. L. Bos, and B. M. Burgering. 1998. Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras. Mol. Cell. Biol. 18:1802-1811.
40. Warne, P. H., P. R. Viciana, and J. Downward. 1993. Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro. Nature 364:352-355.
41. Weinberg, R. A. 1995. The retinoblastoma protein and cell cycle control. Cell 81:323-330.
42. Van, Z., J. DeGregori, R. Shohet, G. Leone, B. Stiliman, J. R. Nevins, and R. S. Williams. 1998. Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. Proc. Natl. Acad. Sci. USA 95:3603-3608.
43. Yen, A., and A. B. Pardee. 1978. Exponential 3T3 cells escape in mid-G1 from their high serum requirement. Exp. Cell Res. 116:103-113.
44. Zetterberg, A., and O. Larsson. 1985. Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc. Natl. Acad. Sci. USA 82:5365-5369.