Transgenic overexpression of Abcb11 enhances biliary bile salt outputs, but does not affect cholesterol cholelithogenesis in mice

European Journal of Clinical Investigation

Volumn 40, Issue 6, 2010, Pages 541-551

  Wang, Helen H ^a   Lammert, Frank ^b   Schmitz, Anne ^b   Wang, David Q H ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Bile; Bile flow; Bile salt; Biliary secretion; Cholesterol saturation index; Crystallization; Liquid crystals; Lith gene; Microscopy

Indexed keywords

ABC TRANSPORTER; BILE SALT; CHOLESTEROL; PHOSPHOLIPID; PROTEIN ABCB11; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE FLOW; BILIARY EXCRETION; CHOLELITHIASIS; CHOLESTEROL CHOLELITHIASIS; CONTROLLED STUDY; DIETARY INTAKE; FLOW RATE; GALLBLADDER CONTRACTION; GALLSTONE FORMATION; GENE OVEREXPRESSION; GENETIC POLYMORPHISM; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN FUNCTION; STRAIN DIFFERENCE; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; CHOLELITHIASIS; CHOLESTEROL, DIETARY; GALLBLADDER; GALLSTONES; LIPIDS; MICE; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 77952615518     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2010.02300.x     Document Type: Article

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