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Volumn 40, Issue 11, 1999, Pages 2080-2090

Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: Integrated activities of hepatic lipid regulatory enzymes

Author keywords

Acyl CoA:cholesterol acyltransferase; Choleslerol 7 hydroxylase; Gallstones; Genetics; HMG CoA reductase; Microscopy; Recombinant inbred mice; Sterol 27 hydroxylase

Indexed keywords

BILE SALT; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLESTEROL ACYLTRANSFERASE; CHOLIC ACID; FAT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LIPID; LIVER ENZYME; STEROID 21 MONOOXYGENASE;

EID: 0032692921     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (68)

References (50)
  • 1
    • 0344671406 scopus 로고    scopus 로고
    • Gallstones
    • R. A. King, J. F. Rotter, and A. G. Motulsky, editors. Oxford University Press, London. In press
    • Paigen, B., and M. C. Carey. 1999. Gallstones. In The Genetic Basis of Common Diseases. R. A. King, J. F. Rotter, and A. G. Motulsky, editors. Oxford University Press, London. In press.
    • (1999) The Genetic Basis of Common Diseases
    • Paigen, B.1    Carey, M.C.2
  • 3
    • 0030893854 scopus 로고    scopus 로고
    • Complex genetic control of hdl levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism
    • Machleder, D., B. Ivandic, C. Welch, L. Castellani, K. Reue, and A. J. Lusis. 1997. Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism. J. Clin. Invest. 99: 1406-1419.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1406-1419
    • Machleder, D.1    Ivandic, B.2    Welch, C.3    Castellani, L.4    Reue, K.5    Lusis, A.J.6
  • 4
    • 0001787345 scopus 로고    scopus 로고
    • Functional and genetic studies of biliary cholesterol secretion in inbred mice: Evidence for a primary role of sister to P-glycoprotein, the canalicular bile salt export pump, in cholesterol gallstone pathogenesis
    • G. Paumgartner, A. Stiehl, W. Gerok, D. Keppler, and U. Leuschner, editors. Kluwer Academic Publishers, Dordrecht.
    • Lammert, F., D. Q-H. Wang, D. E. Cohen, B. Paigen, and M. C. Carey. 1999. Functional and genetic studies of biliary cholesterol secretion in inbred mice: evidence for a primary role of sister to P-glycoprotein, the canalicular bile salt export pump, in cholesterol gallstone pathogenesis. In Bile Acids and Cholestasis, G. Paumgartner, A. Stiehl, W. Gerok, D. Keppler, and U. Leuschner, editors. Kluwer Academic Publishers, Dordrecht. 224-228.
    • (1999) Bile Acids and Cholestasis , pp. 224-228
    • Lammert, F.1    Wang, D.Q.-H.2    Cohen, D.E.3    Paigen, B.4    Carey, M.C.5
  • 6
    • 0030810683 scopus 로고    scopus 로고
    • Phenotypic characterization of lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: Physical-chemistry of gallbladder bile
    • Wang, D. Q-H., B. Paigen, and M. C. Carey. 1997. Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: physical-chemistry of gallbladder bile. J. Lipid Res. 38: 1395-1411.
    • (1997) J. Lipid Res. , vol.38 , pp. 1395-1411
    • Wang, D.Q.-H.1    Paigen, B.2    Carey, M.C.3
  • 7
    • 0032692920 scopus 로고    scopus 로고
    • Phenotypic characterization of lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: Pathophysiology of biliary lipid secretion
    • Wang, D. Q-H., F. Lammert, B. Paigen, and M. C. Carey. 1999. Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: pathophysiology of biliary lipid secretion. J. Lipid Res. 40: 2066-2079.
    • (1999) J. Lipid Res. , vol.40 , pp. 2066-2079
    • Wang, D.Q.-H.1    Lammert, F.2    Paigen, B.3    Carey, M.C.4
  • 8
    • 0027017761 scopus 로고
    • Cholesterol gallstone formation. 2. Pathobiology and pathomechanics
    • LaMont, J. T., and M. C. Carey. 1992. Cholesterol gallstone formation. 2. Pathobiology and pathomechanics. Prog. Liver Dis. 10: 165-191.
    • (1992) Prog. Liver Dis. , vol.10 , pp. 165-191
    • LaMont, J.T.1    Carey, M.C.2
  • 9
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein, J. L., and M. S. Brown. 1990. Regulation of the mevalonate pathway. Nature. 343: 425-430.
    • (1990) Nature. , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 12
    • 0026551710 scopus 로고
    • Mechanism of degradation of the steroid side chain in the formation of bile acids
    • Björkhem, I. 1992. Mechanism of degradation of the steroid side chain in the formation of bile acids. J. Lipid Res. 33: 455-471.
    • (1992) J. Lipid Res. , vol.33 , pp. 455-471
    • Björkhem, I.1
  • 13
    • 0025045782 scopus 로고
    • Potential bile acid precursors in plasma - Possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man
    • Axelsson, M., and J. Sjövall. 1990. Potential bile acid precursors in plasma - possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man. J. Steroid Biochem. 36: 631-640.
    • (1990) J. Steroid Biochem. , vol.36 , pp. 631-640
    • Axelsson, M.1    Sjövall, J.2
  • 14
    • 0025803835 scopus 로고
    • Hepatic cholesterol metabolism in cholesterol gallstone disease
    • Reihnér, E., B. Angelin, I. Björkhem, and K. Einarsson. 1991. Hepatic cholesterol metabolism in cholesterol gallstone disease. J. Lipid Res. 32: 469-475.
    • (1991) J. Lipid Res. , vol.32 , pp. 469-475
    • Reihnér, E.1    Angelin, B.2    Björkhem, I.3    Einarsson, K.4
  • 15
    • 0028278546 scopus 로고
    • Effects of dietary cholesterol on cholesterol and bile acid homeostasis in patients with cholesterol gallstones
    • Kern, F., Jr. 1994. Effects of dietary cholesterol on cholesterol and bile acid homeostasis in patients with cholesterol gallstones. J. Clin. Invest. 93: 1186-1194.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1186-1194
    • Kern F., Jr.1
  • 16
    • 0029017084 scopus 로고
    • Increase of deoxycholate in supersaturated bile of patients with cholesterol gallstone disease and its correlation with de novo synthesis of cholesterol and bile acids in liver, gallbladder emptying, and small intestinal transit
    • Shoda, J., B. F. He, N. Tanaka, Y. Matsuzaki, T. Osuga, S. Yamamori, H. Miyazaki, and J. Sjövall. 1995. Increase of deoxycholate in supersaturated bile of patients with cholesterol gallstone disease and its correlation with de novo synthesis of cholesterol and bile acids in liver, gallbladder emptying, and small intestinal transit. Hepatology. 21: 1291-1302.
    • (1995) Hepatology. , vol.21 , pp. 1291-1302
    • Shoda, J.1    He, B.F.2    Tanaka, N.3    Matsuzaki, Y.4    Osuga, T.5    Yamamori, S.6    Miyazaki, H.7    Sjövall, J.8
  • 17
    • 0029862903 scopus 로고    scopus 로고
    • Hepatic cholesterol metabolism in patients with cholesterol gallstones: Enhanced intracellular transport of cholesterol
    • Ito, T., S. Kawata, Y. Imai, H. Kakimoto, J. M. Trzaskos, and Y. Matsuzawa. 1996. Hepatic cholesterol metabolism in patients with cholesterol gallstones: enhanced intracellular transport of cholesterol. Gastroenterology. 110: 1619-1627.
    • (1996) Gastroenterology , vol.110 , pp. 1619-1627
    • Ito, T.1    Kawata, S.2    Imai, Y.3    Kakimoto, H.4    Trzaskos, J.M.5    Matsuzawa, Y.6
  • 18
    • 0030628631 scopus 로고    scopus 로고
    • Coordinate regulation of cholesterol 7α-hydroxylase and HMG-CoA reductase in the liver
    • R. Bittman, editor. Plenum Press, New York, NY.
    • Björkhem, I., E. Lund, and M. Rudling. 1997. Coordinate regulation of cholesterol 7α-hydroxylase and HMG-CoA reductase in the liver. In Subcellular Biochemistry. Vol. 28. R. Bittman, editor. Plenum Press, New York, NY. 23-55.
    • (1997) Subcellular Biochemistry , vol.28 , pp. 23-55
    • Björkhem, I.1    Lund, E.2    Rudling, M.3
  • 19
    • 0029447565 scopus 로고
    • Strain distribution pattern for SSLP markers in the SWXJ recombinant inbred strain set: Chromosomes 1 to 6
    • Svenson, K. L., Y. C. Cheah, K. L. Shultz, J. L. Mu, B. Paigen, and W. G. Beamer. 1995. Strain distribution pattern for SSLP markers in the SWXJ recombinant inbred strain set: chromosomes 1 to 6. Mamm. Genome. 6: 867-872.
    • (1995) Mamm. Genome. , vol.6 , pp. 867-872
    • Svenson, K.L.1    Cheah, Y.C.2    Shultz, K.L.3    Mu, J.L.4    Paigen, B.5    Beamer, W.G.6
  • 20
    • 0025322603 scopus 로고
    • Synthetic low and high fat diets for study of atherosclerosis in the mouse
    • Nishina, P. M., J. Verstuyft, and B. Paigen. 1990. Synthetic low and high fat diets for study of atherosclerosis in the mouse. J. Lipid Res. 31: 859-869.
    • (1990) J. Lipid Res. , vol.31 , pp. 859-869
    • Nishina, P.M.1    Verstuyft, J.2    Paigen, B.3
  • 21
    • 0027199742 scopus 로고
    • Atherosclerosis and plasma and liver lipids in nine inbred strains of mice
    • Nishina, P. M., J. Wang, W. Toyofoku, F. A. Kuypers, B. Y. Ishida, and B. Paigen. 1993. Atherosclerosis and plasma and liver lipids in nine inbred strains of mice. Lipids. 28: 599-605.
    • (1993) Lipids. , vol.28 , pp. 599-605
    • Nishina, P.M.1    Wang, J.2    Toyofoku, W.3    Kuypers, F.A.4    Ishida, B.Y.5    Paigen, B.6
  • 23
    • 0027428833 scopus 로고
    • Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis by ATP depletion
    • Sato, R., J. L. Goldstein, and M. S. Brown. 1993. Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis by ATP depletion. Proc. Natl. Acad. Sci. USA. 90: 9261-9265.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9261-9265
    • Sato, R.1    Goldstein, J.L.2    Brown, M.S.3
  • 24
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 25
    • 0028979939 scopus 로고
    • Regulation of cholesterol 7α-hydroxylase expression by sterols in primary rat hepatocyte cultures
    • Doerner, K., E. C. Gurley, Z. R. Vlahcevic, and P. B. Hylemon. 1995. Regulation of cholesterol 7α-hydroxylase expression by sterols in primary rat hepatocyte cultures. J. Lipid Res. 36: 1168-1177.
    • (1995) J. Lipid Res. , vol.36 , pp. 1168-1177
    • Doerner, K.1    Gurley, E.C.2    Vlahcevic, Z.R.3    Hylemon, P.B.4
  • 27
    • 0027456308 scopus 로고
    • Synthesis of 27-hydroxycholesterol in rat liver mitochondria: HPLC assay and marked activation by exogenous cholesterol
    • Petrack, B., and B. J. Latario. 1993. Synthesis of 27-hydroxycholesterol in rat liver mitochondria: HPLC assay and marked activation by exogenous cholesterol. J. Lipid Res. 34: 643-649.
    • (1993) J. Lipid Res. , vol.34 , pp. 643-649
    • Petrack, B.1    Latario, B.J.2
  • 28
    • 0021891299 scopus 로고
    • Cholesterol acyltransferase
    • Billheimer, J. T. 1985. Cholesterol acyltransferase. Methods Enzymol. 111: 286-293.
    • (1985) Methods Enzymol. , vol.111 , pp. 286-293
    • Billheimer, J.T.1
  • 29
    • 0029958885 scopus 로고    scopus 로고
    • Complete mapping of crystallization pathways during cholesterol precipitation from model bile: Influence of physical-chemical variables of pathophysiological relevance and identification of a stable liquid crystalline state in cold, dilute and hydrophilic bile-salt containing systems
    • Wang, D. Q-H., and M. C. Carey. 1996. Complete mapping of crystallization pathways during cholesterol precipitation from model bile: influence of physical-chemical variables of pathophysiological relevance and identification of a stable liquid crystalline state in cold, dilute and hydrophilic bile-salt containing systems. J. Lipid Res. 37: 606-630.
    • (1996) J. Lipid Res. , vol.37 , pp. 606-630
    • Wang, D.Q.-H.1    Carey, M.C.2
  • 30
    • 0030454457 scopus 로고    scopus 로고
    • Characterization of crystallization pathways during cholesterol precipitation from human gallbladder biles: Identical pathways to corresponding model biles with three predominating sequences
    • Wang, D. Q-H., and M. C. Carey. 1996. Characterization of crystallization pathways during cholesterol precipitation from human gallbladder biles: identical pathways to corresponding model biles with three predominating sequences. J. Lipid Res. 37: 2539-2549.
    • (1996) J. Lipid Res. , vol.37 , pp. 2539-2549
    • Wang, D.Q.-H.1    Carey, M.C.2
  • 31
    • 0029854823 scopus 로고    scopus 로고
    • Lithogenic diet and gallstone formation in mice: Integrated response of activities of regulatory enzymes in hepatic cholesterol metabolism
    • Reihnér, E., and D. Ståhlberg. 1996. Lithogenic diet and gallstone formation in mice: integrated response of activities of regulatory enzymes in hepatic cholesterol metabolism. Br. J. Nutr. 76: 765-772.
    • (1996) Br. J. Nutr. , vol.76 , pp. 765-772
    • Reihnér, E.1    Ståhlberg, D.2
  • 32
    • 0027288278 scopus 로고
    • Effect of dietary cholesterol and taurocholate on cholesterol 7α-hydroxylase and hepatic LDL receptors in mice
    • Dueland, S., J. Drisko, L. Graf, D. Machleder, A. J. Lusis, and R. A. Davis. 1993. Effect of dietary cholesterol and taurocholate on cholesterol 7α-hydroxylase and hepatic LDL receptors in mice. J. Lipid Res. 34: 923-931.
    • (1993) J. Lipid Res. , vol.34 , pp. 923-931
    • Dueland, S.1    Drisko, J.2    Graf, L.3    Machleder, D.4    Lusis, A.J.5    Davis, R.A.6
  • 33
    • 0032953973 scopus 로고    scopus 로고
    • Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis
    • Wang, D. Q-H., F. Lammert, D. E. Cohen, B. Paigen, and M. C. Carey. 1999. Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis. Am. J. Physiol. 276: G751-G760.
    • (1999) Am. J. Physiol. , vol.276
    • Wang, D.Q.-H.1    Lammert, F.2    Cohen, D.E.3    Paigen, B.4    Carey, M.C.5
  • 35
    • 0028850779 scopus 로고
    • Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes
    • Twisk, J., E. C. de Wit, and H. M. Princen. 1995. Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes. Biochem. J. 205: 505-511.
    • (1995) Biochem. J. , vol.205 , pp. 505-511
    • Twisk, J.1    De Wit, E.C.2    Princen, H.M.3
  • 36
    • 0030009916 scopus 로고    scopus 로고
    • Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes
    • Stravitz, R. T., Z. R. Vlahcevic, T. L. Russell, M. L. Heizer, N. G. Avadhani, and P. B. Hylemon. 1996. Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes. J. Steroid Biochem. 57: 337-347.
    • (1996) J. Steroid Biochem. , vol.57 , pp. 337-347
    • Stravitz, R.T.1    Vlahcevic, Z.R.2    Russell, T.L.3    Heizer, M.L.4    Avadhani, N.G.5    Hylemon, P.B.6
  • 37
    • 0023273466 scopus 로고
    • Different susceptibilities to the formation of cholesterol gallstones in mice
    • Alexander, M., and O. W. Portman. 1987. Different susceptibilities to the formation of cholesterol gallstones in mice. Hepatology. 7: 257-265.
    • (1987) Hepatology. , vol.7 , pp. 257-265
    • Alexander, M.1    Portman, O.W.2
  • 38
    • 0029899036 scopus 로고    scopus 로고
    • Pathogenesis of cholesterol gallstones: A parsimonious hypothesis
    • Apstein, M. D., and M. C. Carey. 1996. Pathogenesis of cholesterol gallstones: a parsimonious hypothesis. Eur. J. Clin. Invest. 26: 343-352.
    • (1996) Eur. J. Clin. Invest. , vol.26 , pp. 343-352
    • Apstein, M.D.1    Carey, M.C.2
  • 40
    • 0028224484 scopus 로고
    • Effects of different bile salts on steady-state mRNA levels and transcriptional activity of cholesterol 7α-hydroxylase
    • Pandak, W. M., Z. R. Vlahcevic, D. M. Heuman, K. S. Redford, J. Y. Chiang, and P. B. Hylemon. 1994. Effects of different bile salts on steady-state mRNA levels and transcriptional activity of cholesterol 7α-hydroxylase. Hepatology. 19: 941-947.
    • (1994) Hepatology. , vol.19 , pp. 941-947
    • Pandak, W.M.1    Vlahcevic, Z.R.2    Heuman, D.M.3    Redford, K.S.4    Chiang, J.Y.5    Hylemon, P.B.6
  • 41
    • 0023256652 scopus 로고
    • Heterogeneity of cholesterol homeostasis in man: Response to changes in dietary fat and cholesterol quantity
    • McNamara, D. J., R. Kolb, T. S. Parker, H. Batwin, P. Samuel, C. D. Brown, and E. H. Ahrens. 1987. Heterogeneity of cholesterol homeostasis in man: response to changes in dietary fat and cholesterol quantity. J. Clin. Invest. 79: 1729-1739.
    • (1987) J. Clin. Invest. , vol.79 , pp. 1729-1739
    • McNamara, D.J.1    Kolb, R.2    Parker, T.S.3    Batwin, H.4    Samuel, P.5    Brown, C.D.6    Ahrens, E.H.7
  • 42
    • 0026525973 scopus 로고
    • Hepatic mRNA levels for the LDL receptor and HMG-CoA reductase show coordinate regulation in vivo
    • Rudling, M. 1992. Hepatic mRNA levels for the LDL receptor and HMG-CoA reductase show coordinate regulation in vivo. J. Lipid Res. 33: 493-501.
    • (1992) J. Lipid Res. , vol.33 , pp. 493-501
    • Rudling, M.1
  • 43
    • 0030933465 scopus 로고    scopus 로고
    • Dietary fats modulate the regulatory potential of dietary cholesterol on cholesterol 7α-hydroxylase gene expression
    • Cheema, S. K., D. Cikaluk, and L. B. Agellon. 1997. Dietary fats modulate the regulatory potential of dietary cholesterol on cholesterol 7α-hydroxylase gene expression. J. Lipid Res. 38: 315-333.
    • (1997) J. Lipid Res. , vol.38 , pp. 315-333
    • Cheema, S.K.1    Cikaluk, D.2    Agellon, L.B.3
  • 44
    • 0001053857 scopus 로고
    • Regulation of hepatic metabolism of free fatty acids: Interrelationships among secretion of very-low-density lipoproteins, ketogenesis, and cholesterogenesis
    • J. M. Dietschy, A. M. Gotto, and J. A. Ontko, editors. American Physiological Society, Bethesda, MD.
    • Heimberg, M., E. H. Goh, H. J. Klausner, C. Soler-Argilaga, I. Weinstein, and H. G. Wilcox. 1978. Regulation of hepatic metabolism of free fatty acids: Interrelationships among secretion of very-low-density lipoproteins, ketogenesis, and cholesterogenesis. In Disturbances in Lipid and Lipoprotein Metabolism. J. M. Dietschy, A. M. Gotto, and J. A. Ontko, editors. American Physiological Society, Bethesda, MD. 251-267.
    • (1978) Disturbances in Lipid and Lipoprotein Metabolism , pp. 251-267
    • Heimberg, M.1    Goh, E.H.2    Klausner, H.J.3    Soler-Argilaga, C.4    Weinstein, I.5    Wilcox, H.G.6
  • 45
    • 0030763198 scopus 로고    scopus 로고
    • High density lipoproteins, but not other lipoproteins provide a vehicle for sterol transport to bile
    • Robins, S. J., and J. M. Fasulo. 1997. High density lipoproteins, but not other lipoproteins provide a vehicle for sterol transport to bile. J. Clin. Invest. 99: 380-384.
    • (1997) J. Clin. Invest. , vol.99 , pp. 380-384
    • Robins, S.J.1    Fasulo, J.M.2
  • 46
    • 0031263042 scopus 로고    scopus 로고
    • Homing-in on the origin of biliary steroids
    • Carey, M. C. 1997. Homing-in on the origin of biliary steroids. Gut. 41: 721-722.
    • (1997) Gut. , vol.41 , pp. 721-722
    • Carey, M.C.1
  • 48
    • 0032533544 scopus 로고    scopus 로고
    • Sterol carrier protein 2 participates in hypersecretion of biliary cholesterol during gallstone formation in genetically gallstone-susceptible mice
    • Fuchs, M., F. Lammert, D. Q-H. Wang, B. Paigen, M. C. Carey, and D. E. Cohen. 1998. Sterol carrier protein 2 participates in hypersecretion of biliary cholesterol during gallstone formation in genetically gallstone-susceptible mice. Biochem. J. 336: 33-37.
    • (1998) Biochem. J. , vol.336 , pp. 33-37
    • Fuchs, M.1    Lammert, F.2    Wang, D.Q.-H.3    Paigen, B.4    Carey, M.C.5    Cohen, D.E.6
  • 49
    • 0029817701 scopus 로고    scopus 로고
    • Modulation of intrahepatic cholesterol trafficking: Evidence by in vivo antisense treatment for the involvement of sterol carrier protein-2 in newly synthesized cholesterol transport into bile
    • Puglielli, L., A. Rigotti, L. Amigo, L. Nuñez, A. V. Greco, M. J. Santos, and F. Nervi. 1996. Modulation of intrahepatic cholesterol trafficking: evidence by in vivo antisense treatment for the involvement of sterol carrier protein-2 in newly synthesized cholesterol transport into bile. Biochem. J. 317: 681-687.
    • (1996) Biochem. J. , vol.317 , pp. 681-687
    • Puglielli, L.1    Rigotti, A.2    Amigo, L.3    Nuñez, L.4    Greco, A.V.5    Santos, M.J.6    Nervi, F.7
  • 50
    • 0030211231 scopus 로고    scopus 로고
    • Assignment of the mouse sterol carrier protein gene (Scp2) to chromosome 4
    • Welch, C. L., Y. R. Xia, J. T. Billheimer, J. F. Strauss, and A. J. Lusis. 1996. Assignment of the mouse sterol carrier protein gene (Scp2) to chromosome 4. Mamm. Genome. 7: 624-625.
    • (1996) Mamm. Genome. , vol.7 , pp. 624-625
    • Welch, C.L.1    Xia, Y.R.2    Billheimer, J.T.3    Strauss, J.F.4    Lusis, A.J.5


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