메뉴 건너뛰기




Volumn 51, Issue 1, 2010, Pages 277-285

Mechanisms for increased expression of cholesterol 7α-hydroxylase (Cyp7a1) in lactating rats

Author keywords

[No Author keywords available]

Indexed keywords

CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 2; CHOLESTEROL 7ALPHA MONOOXYGENASE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 15; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LIVER RECEPTOR HOMOLOG 1; LIVER X RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN C JUN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 73449095228     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.23289     Document Type: Article
Times cited : (19)

References (44)
  • 1
    • 0037790917 scopus 로고    scopus 로고
    • The enzymes, regulation, and genetics of bile acid synthesis
    • Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem 2003;72:137-174.
    • (2003) Annu Rev Biochem , vol.72 , pp. 137-174
    • Russell, D.W.1
  • 2
    • 0025269939 scopus 로고
    • Cloning and regulation of cholesterol 7α-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis
    • Jelinek DF, Andersson S, Slaughter CA, Russell DW. Cloning and regulation of cholesterol 7α-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis. J Biol Chem 1990;265:8190-8197.
    • (1990) J Biol Chem , vol.265 , pp. 8190-8197
    • Jelinek, D.F.1    Andersson, S.2    Slaughter, C.A.3    Russell, D.W.4
  • 3
    • 0025353861 scopus 로고
    • Regulation of cholesterol 7 α-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7α-hydroxylase mRNA
    • Li YC, Wang DP, Chiang JY. Regulation of cholesterol 7 α-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7α-hydroxylase mRNA. J Biol Chem 1990;265:12012-12019.
    • (1990) J Biol Chem , vol.265 , pp. 12012-12019
    • Li, Y.C.1    Wang, D.P.2    Chiang, J.Y.3
  • 4
    • 0028300020 scopus 로고
    • Cholesterol and bile acids regulate cholesterol 7α-hydroxylase expression at the transcriptional level in culture and in transgenic mice
    • Ramirez MI, Karaoglu D, Haro D, Barillas C, Bashirzadeh R, Gil G. Cholesterol and bile acids regulate cholesterol 7α-hydroxylase expression at the transcriptional level in culture and in transgenic mice. Mol Cell Biol 1994;14:2809-2821.
    • (1994) Mol Cell Biol , vol.14 , pp. 2809-2821
    • Ramirez, M.I.1    Karaoglu, D.2    Haro, D.3    Barillas, C.4    Bashirzadeh, R.5    Gil, G.6
  • 5
  • 6
    • 0035834868 scopus 로고    scopus 로고
    • Regulation of cholesterol 7α-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRα)
    • Chiang JY, Kimmel R, Stroup D. Regulation of cholesterol 7α-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRα). Gene 2001;262:257-265.
    • (2001) Gene , vol.262 , pp. 257-265
    • Chiang, J.Y.1    Kimmel, R.2    Stroup, D.3
  • 7
    • 0013199471 scopus 로고    scopus 로고
    • Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
    • Peet DJ, Turley SD, Ma W, Janowski BA, Lobaccaro JM, Hammer RE, et al. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 1998;93:693-704.
    • (1998) Cell , vol.93 , pp. 693-704
    • Peet, D.J.1    Turley, S.D.2    Ma, W.3    Janowski, B.A.4    Lobaccaro, J.M.5    Hammer, R.E.6
  • 8
    • 33845587711 scopus 로고    scopus 로고
    • Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice
    • Chen W, Chen G, Head DL, Mangelsdorf DJ, Russell DW. Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. Cell Metab 2007;5:73-79.
    • (2007) Cell Metab , vol.5 , pp. 73-79
    • Chen, W.1    Chen, G.2    Head, D.L.3    Mangelsdorf, D.J.4    Russell, D.W.5
  • 9
    • 34548745142 scopus 로고    scopus 로고
    • Insights in the regulation of cholesterol 7α-hydroxylase gene reveal a target for modulating bile acid synthesis
    • Mitro N, Godio C, De Fabiani E, Scotti E, Galmozzi A, Gilardi F, et al. Insights in the regulation of cholesterol 7α-hydroxylase gene reveal a target for modulating bile acid synthesis. HEPATOLOGY 2007;46:885-897.
    • (2007) HEPATOLOGY , vol.46 , pp. 885-897
    • Mitro, N.1    Godio, C.2    De Fabiani, E.3    Scotti, E.4    Galmozzi, A.5    Gilardi, F.6
  • 10
    • 0031751631 scopus 로고    scopus 로고
    • Transcriptional activation of the cholesterol 7α-hydroxylase gene (CYP7A) by nuclear hormone receptors
    • Crestani M, Sadeghpour A, Stroup D, Galli G, Chiang JY. Transcriptional activation of the cholesterol 7α-hydroxylase gene (CYP7A) by nuclear hormone receptors. J Lipid Res 1998;39:2192-2200.
    • (1998) J Lipid Res , vol.39 , pp. 2192-2200
    • Crestani, M.1    Sadeghpour, A.2    Stroup, D.3    Galli, G.4    Chiang, J.Y.5
  • 11
    • 0030950233 scopus 로고    scopus 로고
    • Orphan receptors chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and retinoid X receptor (RXR) activate and bind the rat cholesterol 7α-hydroxylase gene (CYP7A)
    • Stroup D, Crestani M, Chiang JY. Orphan receptors chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and retinoid X receptor (RXR) activate and bind the rat cholesterol 7α-hydroxylase gene (CYP7A). J Biol Chem 1997;272:9833-9839.
    • (1997) J Biol Chem , vol.272 , pp. 9833-9839
    • Stroup, D.1    Crestani, M.2    Chiang, J.Y.3
  • 12
    • 0033637121 scopus 로고    scopus 로고
    • A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
    • Goodwin B, Jones SA, Price RR, Watson MA, McKee DD, Moore LB, et al. A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol Cell 2000;6:517-526.
    • (2000) Mol Cell , vol.6 , pp. 517-526
    • Goodwin, B.1    Jones, S.A.2    Price, R.R.3    Watson, M.A.4    McKee, D.D.5    Moore, L.B.6
  • 13
    • 0034666027 scopus 로고    scopus 로고
    • Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7α-hydroxylase transcription
    • del Castillo-Olivares A, Gil G. Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7α-hydroxylase transcription. Nucleic Acids Res 2000;28:3587-3593.
    • (2000) Nucleic Acids Res , vol.28 , pp. 3587-3593
    • del Castillo-Olivares, A.1    Gil, G.2
  • 14
    • 0033636789 scopus 로고    scopus 로고
    • Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
    • Lu TT, Makishima M, Repa JJ, Schoonjans K, Kerr TA, Auwerx J, et al. Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol Cell 2000;6:507-515.
    • (2000) Mol Cell , vol.6 , pp. 507-515
    • Lu, T.T.1    Makishima, M.2    Repa, J.J.3    Schoonjans, K.4    Kerr, T.A.5    Auwerx, J.6
  • 15
    • 37749028981 scopus 로고    scopus 로고
    • Hepatocyte growth factor signaling pathway inhibits cholesterol 7α-hydroxylase and bile acid synthesis in human hepatocytes
    • Song KH, Ellis E, Strom S, Chiang JY. Hepatocyte growth factor signaling pathway inhibits cholesterol 7α-hydroxylase and bile acid synthesis in human hepatocytes. HEPATOLOGY 2007;46:1993-2002.
    • (2007) HEPATOLOGY , vol.46 , pp. 1993-2002
    • Song, K.H.1    Ellis, E.2    Strom, S.3    Chiang, J.Y.4
  • 16
    • 0037663483 scopus 로고    scopus 로고
    • Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis
    • Holt JA, Luo G, Billin AN, Bisi J, McNeill YY, Kozarsky KF, et al. Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. Genes Dev 2003;17:1581-1591.
    • (2003) Genes Dev , vol.17 , pp. 1581-1591
    • Holt, J.A.1    Luo, G.2    Billin, A.N.3    Bisi, J.4    McNeill, Y.Y.5    Kozarsky, K.F.6
  • 17
    • 27844546989 scopus 로고    scopus 로고
    • Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
    • Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, et al. Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab 2005;2:217-225.
    • (2005) Cell Metab , vol.2 , pp. 217-225
    • Inagaki, T.1    Choi, M.2    Moschetta, A.3    Peng, L.4    Cummins, C.L.5    McDonald, J.G.6
  • 18
    • 23644451052 scopus 로고    scopus 로고
    • Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids
    • Yu C, Wang F, Jin C, Huang X, McKeehan WL. Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids. J Biol Chem 2005;280:17707-17714.
    • (2005) J Biol Chem , vol.280 , pp. 17707-17714
    • Yu, C.1    Wang, F.2    Jin, C.3    Huang, X.4    McKeehan, W.L.5
  • 19
    • 58949097425 scopus 로고    scopus 로고
    • Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α-hydroxylase gene expression
    • Song K-H, Li T, Owsley E, Strom S, Chiang JYL. Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α-hydroxylase gene expression. HEPATOLOGY 2009;49:297-305.
    • (2009) HEPATOLOGY , vol.49 , pp. 297-305
    • Song, K.-H.1    Li, T.2    Owsley, E.3    Strom, S.4    Chiang, J.Y.L.5
  • 20
    • 42049099023 scopus 로고    scopus 로고
    • Increased cholesterol 7α-hydroxylase expression and size of the bile acid pool in the lactating rat
    • Wooton-Kee CR, Cohen DE, Vore M. Increased cholesterol 7α-hydroxylase expression and size of the bile acid pool in the lactating rat. Am J Physiol Gastrointest Liver Physiol 2008;294:G1009-1016.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Wooton-Kee, C.R.1    Cohen, D.E.2    Vore, M.3
  • 21
    • 0030994363 scopus 로고    scopus 로고
    • Regulation of the rat liver sodium-dependent bile acid cotransporter gene by prolactin
    • Ganguly TC, O'Brien ML, Karpen SJ, Hyde JF, Such FJ, Vore M. Regulation of the rat liver sodium-dependent bile acid cotransporter gene by prolactin. J Clin Invest 1997;99:2906-2914.
    • (1997) J Clin Invest , vol.99 , pp. 2906-2914
    • Ganguly, T.C.1    O'Brien, M.L.2    Karpen, S.J.3    Hyde, J.F.4    Such, F.J.5    Vore, M.6
  • 22
    • 0035192777 scopus 로고    scopus 로고
    • Differential regulation of hepatic bile salt and organic anion transporters in pregnant and postpartum rats and the role of prolactin
    • Cao H, Huang L, Liu Y, Hoffman T, Stieger B, Meier PJ, et al. Differential regulation of hepatic bile salt and organic anion transporters in pregnant and postpartum rats and the role of prolactin. HEPATOLOGY 2001;33:140-147.
    • (2001) HEPATOLOGY , vol.33 , pp. 140-147
    • Cao, H.1    Huang, L.2    Liu, Y.3    Hoffman, T.4    Stieger, B.5    Meier, P.J.6
  • 23
    • 0036024957 scopus 로고    scopus 로고
    • Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation
    • Wells J, Farnham PJ. Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation. Methods 2002;26:48-56.
    • (2002) Methods , vol.26 , pp. 48-56
    • Wells, J.1    Farnham, P.J.2
  • 24
    • 1842531011 scopus 로고    scopus 로고
    • The glucocorticoid receptor and the orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II interact with and mutually affect each other's transcriptional activities: Implications for intermediary metabolism
    • DeMartino MU, Bhattachryya N, Alesci S, Ichijo T, Chrousos GP, Kino T. The glucocorticoid receptor and the orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II interact with and mutually affect each other's transcriptional activities: implications for intermediary metabolism. Mol Endocrinol 2004;18:820-833.
    • (2004) Mol Endocrinol , vol.18 , pp. 820-833
    • DeMartino, M.U.1    Bhattachryya, N.2    Alesci, S.3    Ichijo, T.4    Chrousos, G.P.5    Kino, T.6
  • 25
    • 34249275727 scopus 로고    scopus 로고
    • Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism
    • Liu C, Li S, Liu T, Borjigin J, Lin JD. Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism. Nature 2007;447:477-481.
    • (2007) Nature , vol.447 , pp. 477-481
    • Liu, C.1    Li, S.2    Liu, T.3    Borjigin, J.4    Lin, J.D.5
  • 27
    • 33745529832 scopus 로고    scopus 로고
    • Bile acids and cytokines inhibit the human cholesterol 7α-hydroxylase gene via the JNK/c-jun pathway in human liver cells
    • Li T, Jahan A, Chiang JY. Bile acids and cytokines inhibit the human cholesterol 7α-hydroxylase gene via the JNK/c-jun pathway in human liver cells. HEPATOLOGY 2006;43:1202-1210.
    • (2006) HEPATOLOGY , vol.43 , pp. 1202-1210
    • Li, T.1    Jahan, A.2    Chiang, J.Y.3
  • 28
    • 18444377348 scopus 로고    scopus 로고
    • Redundant pathways for negative feedback regulation of bile acid production
    • Wang L, Lee YK, Bundman D, Han Y, Thevananther S, Kim CS, et al. Redundant pathways for negative feedback regulation of bile acid production. Dev Cell 2002;2:721-731.
    • (2002) Dev Cell , vol.2 , pp. 721-731
    • Wang, L.1    Lee, Y.K.2    Bundman, D.3    Han, Y.4    Thevananther, S.5    Kim, C.S.6
  • 29
    • 33747157406 scopus 로고    scopus 로고
    • Nuclear receptor expression links the circadian clock to metabolism
    • Yang X, Downes M, Yu RT, Bookout AL, He W, Straume M, et al. Nuclear receptor expression links the circadian clock to metabolism. Cell 2006;126:801-810.
    • (2006) Cell , vol.126 , pp. 801-810
    • Yang, X.1    Downes, M.2    Yu, R.T.3    Bookout, A.L.4    He, W.5    Straume, M.6
  • 30
    • 33846140784 scopus 로고    scopus 로고
    • Synergistic regulation of the mouse orphan nuclear receptor SHP gene promoter by CLOCK-BMAL1 and LRH-1
    • Oiwa A, Kakizawa T, Miyamoto T, Yamashita K, Jiang W, Takeda T, et al. Synergistic regulation of the mouse orphan nuclear receptor SHP gene promoter by CLOCK-BMAL1 and LRH-1. Biochem Biophys Res Commun 2007;353:895-901.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 895-901
    • Oiwa, A.1    Kakizawa, T.2    Miyamoto, T.3    Yamashita, K.4    Jiang, W.5    Takeda, T.6
  • 31
    • 37249015421 scopus 로고    scopus 로고
    • Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine
    • Kim I, Ahn SH, Inagaki T, Choi M, Ito S, Guo GL, et al. Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine. J Lipid Res 2007;48:2664-2672.
    • (2007) J Lipid Res , vol.48 , pp. 2664-2672
    • Kim, I.1    Ahn, S.H.2    Inagaki, T.3    Choi, M.4    Ito, S.5    Guo, G.L.6
  • 32
    • 0020560028 scopus 로고
    • Regulation of cholesterol synthesis in the liver and mammary gland of the lactating rat
    • Gibbons GF, Pullinger CR, Munday MR, Williamson DH. Regulation of cholesterol synthesis in the liver and mammary gland of the lactating rat. Biochem J 1983;212:843-848.
    • (1983) Biochem J , vol.212 , pp. 843-848
    • Gibbons, G.F.1    Pullinger, C.R.2    Munday, M.R.3    Williamson, D.H.4
  • 33
    • 0022106729 scopus 로고
    • Effect of lactation on cholesterol synthesis in rats
    • Feingold KR, Moser AH. Effect of lactation on cholesterol synthesis in rats. Am J Physiol 1985;249:G203-208.
    • (1985) Am J Physiol , vol.249
    • Feingold, K.R.1    Moser, A.H.2
  • 34
    • 0013860808 scopus 로고
    • Origin of milk cholesterol in the rat: Dietary versus endogenous sources
    • Clarenburg R, Chaikoff IL. Origin of milk cholesterol in the rat: dietary versus endogenous sources. J Lipid Res 1966;7:27-37.
    • (1966) J Lipid Res , vol.7 , pp. 27-37
    • Clarenburg, R.1    Chaikoff, I.L.2
  • 35
    • 70349430938 scopus 로고    scopus 로고
    • Bile acids: Regulation of synthesis
    • Chiang JYL. Bile acids: regulation of synthesis. J Lipid Res 2009;50:1955-1966.
    • (2009) J Lipid Res , vol.50 , pp. 1955-1966
    • Chiang, J.Y.L.1
  • 36
    • 0036086509 scopus 로고    scopus 로고
    • Loss of nuclear receptor SHP imparis but does not eliminate negative feedback regulation of bile acid synthesis
    • Kerr TA, Saeki S, Schnieder M, Schaefer K, Berdy S, Redder T, et al. Loss of nuclear receptor SHP imparis but does not eliminate negative feedback regulation of bile acid synthesis. Dev Cell 2002;2:713-720.
    • (2002) Dev Cell , vol.2 , pp. 713-720
    • Kerr, T.A.1    Saeki, S.2    Schnieder, M.3    Schaefer, K.4    Berdy, S.5    Redder, T.6
  • 37
  • 39
  • 40
    • 2542505481 scopus 로고    scopus 로고
    • Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes
    • Fu L, John LM, Adams SH, Yu XX, Tomlinson E, Renz M, et al, Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes. Endocrinology 2004;145:2594-2603.
    • (2004) Endocrinology , vol.145 , pp. 2594-2603
    • Fu, L.1    John, L.M.2    Adams, S.H.3    Yu, X.X.4    Tomlinson, E.5    Renz, M.6
  • 43
    • 0029086640 scopus 로고
    • Modulation of hepatocyte growth factor and c-met in the rat mammary gland during pregnancy, lactation, and involution
    • Pepper MS, Soriano JV, Menoud PA, Sappino AP, Orci L, Montesano R. Modulation of hepatocyte growth factor and c-met in the rat mammary gland during pregnancy, lactation, and involution. Exp Cell Res 1995;219:204-10.
    • (1995) Exp Cell Res , vol.219 , pp. 204-210
    • Pepper, M.S.1    Soriano, J.V.2    Menoud, P.A.3    Sappino, A.P.4    Orci, L.5    Montesano, R.6
  • 44
    • 0034978930 scopus 로고    scopus 로고
    • Expression of multidrug resistance-associated protein 2 in small intestine form pregnant and postpartum rats
    • Mottino AD, Hoffman T, Jennes L, Cao J, Vore M. Expression of multidrug resistance-associated protein 2 in small intestine form pregnant and postpartum rats. Am J Physiol Gastrointest Liver Physiol 2001;280:G1261-G1273.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280
    • Mottino, A.D.1    Hoffman, T.2    Jennes, L.3    Cao, J.4    Vore, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.