Azole resistance profile of amino acid changes in Aspergillus fumigatus CYP51A based on protein homology modeling

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 6, 2010, Pages 2425-2430

  Snelders, Eveline ^a   Karawajczyk, Anna ^b   Schaftenaar, Gijs ^b   Verweij, Paul E ^a   Melchers, Willem J G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 51 A; HISTIDINE; LEUCINE; PYRROLE DERIVATIVE; STEROL 14ALPHA DEMETHYLASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIFUNGAL RESISTANCE; ARTICLE; ASPERGILLUS FUMIGATUS; CODON; CORRELATION ANALYSIS; DRUG SENSITIVITY; GENE; GENE MUTATION; GENETIC VARIABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; STRAIN DIFFERENCE; TANDEM REPEAT;

AMINO ACID SUBSTITUTION; ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; AZOLES; CYTOCHROME P-450 ENZYME SYSTEM; DRUG RESISTANCE, FUNGAL; FUNGAL PROTEINS; GENES, FUNGAL; HUMANS; MODELS, MOLECULAR; MUTATION, MISSENSE; PROTEIN CONFORMATION; STRUCTURAL HOMOLOGY, PROTEIN; TANDEM REPEAT SEQUENCES;

EID: 77952597776     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01599-09     Document Type: Article

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