-
1
-
-
0027404624
-
Vitamin D, calcium, and epidermal differentiation
-
Bikle DD, Pillai S (1993) Vitamin D, calcium, and epidermal differentiation. Endocr Rev 14:3-19
-
(1993)
Endocr Rev
, vol.14
, pp. 3-19
-
-
Bikle, D.D.1
Pillai, S.2
-
2
-
-
0025980571
-
Role of intracellular-free calcium in the cornified envelope formation of keratinocytes: Differences in the mode of action of extracellular calcium and 1,25 dihydroxyvitamin D3
-
Pillai S, Bikle DD (1991) Role of intracellular-free calcium in the cornified envelope formation of keratinocytes: differences in the mode of action of extracellular calcium and 1,25 dihydroxyvitamin D3. J Cell Physiol 146:94-100
-
(1991)
J Cell Physiol
, vol.146
, pp. 94-100
-
-
Pillai, S.1
Bikle, D.D.2
-
3
-
-
0025815567
-
Squamous carcinoma cell lines produce 1,25 dihydroxyvitamin D, but fail to respond to its prodifferentiating effect
-
Bikle DD, Pillai S, Gee E (1991) Squamous carcinoma cell lines produce 1,25 dihydroxyvitamin D, but fail to respond to its prodifferentiating effect. J Invest Dermatol 97:435-441
-
(1991)
J Invest Dermatol
, vol.97
, pp. 435-441
-
-
Bikle, D.D.1
Pillai, S.2
Gee, E.3
-
4
-
-
0021087906
-
Regulation of terminal differentiation of cultured mouse epidermal cells by 1-alpha, 25-dihydroxyvitamin D3
-
Hosomi J, Hosoi J, Abe E, Suda T, Kuroki T (1983) Regulation of terminal differentiation of cultured mouse epidermal cells by 1-alpha, 25-dihydroxyvitamin D3. Endocrinology 113:1950-1957
-
(1983)
Endocrinology
, vol.113
, pp. 1950-1957
-
-
Hosomi, J.1
Hosoi, J.2
Abe, E.3
Suda, T.4
Kuroki, T.5
-
5
-
-
0022621042
-
Effect of 1-alpha, 25-dihydroxyvitamin D3 on the morphologic and biochemical differentiation of cultured human epidermal keratinocytes grown in serum-free conditions
-
Smith EL, Walworth NC, Holick MF (1986) Effect of 1-alpha, 25-dihydroxyvitamin D3 on the morphologic and biochemical differentiation of cultured human epidermal keratinocytes grown in serum-free conditions. J Invest Dermatol 86:709-714
-
(1986)
J Invest Dermatol
, vol.86
, pp. 709-714
-
-
Smith, E.L.1
Walworth, N.C.2
Holick, M.F.3
-
6
-
-
0025291364
-
Effect of 1,25-dihydroxyvitamin D3 on human keratinocytes grown under different culture conditions
-
McLane JA, Katz M, Abdelkader N (1990) Effect of 1,25-dihydroxyvitamin D3 on human keratinocytes grown under different culture conditions. In Vitro Cell Dev Biol 26:379-387
-
(1990)
In Vitro Cell Dev Biol
, vol.26
, pp. 379-387
-
-
McLane, J.A.1
Katz, M.2
Abdelkader, N.3
-
7
-
-
33947211993
-
Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3
-
Hawker NP, Pennypacker SD, Chang SM, Bikle DD (2007) Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3. J Invest Dermatol 127:874
-
(2007)
J Invest Dermatol
, vol.127
, pp. 874
-
-
Hawker, N.P.1
Pennypacker, S.D.2
Chang, S.M.3
Bikle, D.D.4
-
8
-
-
0025022398
-
3 on normal human keratinocytes cultured in serum-free medium
-
DOI 10.1016/0006-291X(90)90898-W
-
Matsumoto K, Hashimoto K, Nishida Y, Hashiro M, Yoshikawa K (1990) Growth-inhibitory effects of 1,25-dihydroxyvitamin D3 on normal human keratinocytes cultured in serum-free medium. Biochem Biophys Res Commun 166:916-923 (Pubitemid 20049933)
-
(1990)
Biochemical and Biophysical Research Communications
, vol.166
, Issue.2
, pp. 916-923
-
-
Matsumoto, K.1
Hashimoto, K.2
Nishida, Y.3
Hashiro, M.4
Yoshikawa, K.5
-
9
-
-
67349174964
-
Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation
-
Oda Y, Uchida Y, Moradian S, Crumrine D, Elias PM, Bikle DD (2009) Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation. J Invest Dermatol 129:1367-1378
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1367-1378
-
-
Oda, Y.1
Uchida, Y.2
Moradian, S.3
Crumrine, D.4
Elias, P.M.5
Bikle, D.D.6
-
10
-
-
33847220444
-
Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism
-
Schauber J, Dorschner RA, Coda AB, Buchau AS, Liu PT, Kiken D, Helfrich YR, Kang S, Elalieh HZ, Steinmeyer A, Zugel U, Bikle DD, Modlin RL, Gallo RL (2007) Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. J Clin Invest 117:803-811
-
(2007)
J Clin Invest
, vol.117
, pp. 803-811
-
-
Schauber, J.1
Dorschner, R.A.2
Coda, A.B.3
Buchau, A.S.4
Liu, P.T.5
Kiken, D.6
Helfrich, Y.R.7
Kang, S.8
Elalieh, H.Z.9
Steinmeyer, A.10
Zugel, U.11
Bikle, D.D.12
Modlin, R.L.13
Gallo, R.L.14
-
11
-
-
33746087225
-
Control of the innate epithelial antimicrobial response is cell-type specific and dependent on relevant microenvironmental stimuli
-
Schauber J, Dorschner RA, Yamasaki K, Brouha B, Gallo RL (2006) Control of the innate epithelial antimicrobial response is cell-type specific and dependent on relevant microenvironmental stimuli. Immunology 118:509-519
-
(2006)
Immunology
, vol.118
, pp. 509-519
-
-
Schauber, J.1
Dorschner, R.A.2
Yamasaki, K.3
Brouha, B.4
Gallo, R.L.5
-
12
-
-
0030610422
-
Targeted ablation of the vitamin D receptor: An animal model of vitamin D-dependent rickets type II with alopecia
-
Li YC, Pirro AE, Amling M, Delling G, Baron R, Bronson R, Demay MB (1997) Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia. Proc Natl Acad Sci USA 94:9831-9835
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9831-9835
-
-
Li, Y.C.1
Pirro, A.E.2
Amling, M.3
Delling, G.4
Baron, R.5
Bronson, R.6
Demay, M.B.7
-
13
-
-
2342571726
-
25 Hydroxyvitamin D 1-alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis
-
Bikle DD, Chang S, Crumrine D, Elalieh H, Man MQ, Choi EH, Dardenne O, Xie Z, Arnaud RS, Feingold K, Elias PM (2004) 25 Hydroxyvitamin D 1-alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis. J Invest Dermatol 122:984-992
-
(2004)
J Invest Dermatol
, vol.122
, pp. 984-992
-
-
Bikle, D.D.1
Chang, S.2
Crumrine, D.3
Elalieh, H.4
Man, M.Q.5
Choi, E.H.6
Dardenne, O.7
Xie, Z.8
Arnaud, R.S.9
Feingold, K.10
Elias, P.M.11
-
14
-
-
0036151233
-
Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth
-
Xie Z, Komuves L, Yu QC, Elalieh H, Ng DC, Leary C, Chang S, Crumrine D, Yoshizawa T, Kato S, Bikle DD (2002) Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth. J Invest Dermatol 118:11-16
-
(2002)
J Invest Dermatol
, vol.118
, pp. 11-16
-
-
Xie, Z.1
Komuves, L.2
Yu, Q.C.3
Elalieh, H.4
Ng, D.C.5
Leary, C.6
Chang, S.7
Crumrine, D.8
Yoshizawa, T.9
Kato, S.10
Bikle, D.D.11
-
15
-
-
33645671653
-
Development and progression of alopecia in the vitamin D receptor null mouse
-
Bikle DD, Elalieh H, Chang S, Xie Z, Sundberg JP (2006) Development and progression of alopecia in the vitamin D receptor null mouse. J Cell Physiol 207:340-353
-
(2006)
J Cell Physiol
, vol.207
, pp. 340-353
-
-
Bikle, D.D.1
Elalieh, H.2
Chang, S.3
Xie, Z.4
Sundberg, J.P.5
-
16
-
-
0035092887
-
Extrarenal expression of 25-hydroxyvitamin D(3)-1 alpha-hydroxylase
-
Zehnder D, Bland R, Williams MC, McNinch RW, Howie AJ, Stewart PM, Hewison M (2001) Extrarenal expression of 25-hydroxyvitamin D(3)-1 alpha-hydroxylase. J Clin Endocrinol Metab 86:888-894
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 888-894
-
-
Zehnder, D.1
Bland, R.2
Williams, M.C.3
McNinch, R.W.4
Howie, A.J.5
Stewart, P.M.6
Hewison, M.7
-
17
-
-
0025823930
-
Expression of 1,25-dihydroxyvitamin D3 receptors in normal and psoriatic skin
-
Milde P, Hauser U, Simon T, Mall G, Ernst V, Haussler MR, Frosch P, Rauterberg EW (1991) Expression of 1,25-dihydroxyvitamin D3 receptors in normal and psoriatic skin. J Invest Dermatol 97:230-239
-
(1991)
J Invest Dermatol
, vol.97
, pp. 230-239
-
-
Milde, P.1
Hauser, U.2
Simon, T.3
Mall, G.4
Ernst, V.5
Haussler, M.R.6
Frosch, P.7
Rauterberg, E.W.8
-
18
-
-
0021674565
-
Topographical and developmental studies on target sites of 1,25 (OH)2 vitamin D3 in skin
-
Stumpf WE, Clark SA, Sar M, DeLuca HF (1984) Topographical and developmental studies on target sites of 1,25 (OH)2 vitamin D3 in skin. Cell Tissue Res 238:489-496
-
(1984)
Cell Tissue Res
, vol.238
, pp. 489-496
-
-
Stumpf, W.E.1
Clark, S.A.2
Sar, M.3
DeLuca, H.F.4
-
19
-
-
0242298713
-
Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in vitamin D receptor transactivation during keratinocyte differentiation
-
Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang CP, Burlingame AL, Freedman LP, Bikle DD (2003) Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in vitamin D receptor transactivation during keratinocyte differentiation. Mol Endocrinol 17:2329-2339
-
(2003)
Mol Endocrinol
, vol.17
, pp. 2329-2339
-
-
Oda, Y.1
Sihlbom, C.2
Chalkley, R.J.3
Huang, L.4
Rachez, C.5
Chang, C.P.6
Burlingame, A.L.7
Freedman, L.P.8
Bikle, D.D.9
-
20
-
-
0033305547
-
Nuclear receptor coregulators: Cellular and molecular biology
-
McKenna NJ, Lanz RB, O'Malley BW (1999) Nuclear receptor coregulators: cellular and molecular biology. Endocr Rev 20:321-344
-
(1999)
Endocr Rev
, vol.20
, pp. 321-344
-
-
McKenna, N.J.1
Lanz, R.B.2
O'Malley, B.W.3
-
21
-
-
33947139219
-
Differential role of two VDR coactivators, DRIP205 and SRC-3, in keratinocyte proliferation and differentiation
-
Oda Y, Ishikawa MH, Hawker NP, Yun QC, Bikle DD (2007) Differential role of two VDR coactivators, DRIP205 and SRC-3, in keratinocyte proliferation and differentiation. J Steroid Biochem Mol Biol 103:776-780
-
(2007)
J Steroid Biochem Mol Biol
, vol.103
, pp. 776-780
-
-
Oda, Y.1
Ishikawa, M.H.2
Hawker, N.P.3
Yun, Q.C.4
Bikle, D.D.5
-
22
-
-
40649127503
-
Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3
-
Schauber J, Oda Y, Buchau AS, Steinmeyer A, Zugel U, Bikle DD, Gallo RL (2008) Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. J Invest Dermatol 128:816-824
-
(2008)
J Invest Dermatol
, vol.128
, pp. 816-824
-
-
Schauber, J.1
Oda, Y.2
Buchau, A.S.3
Steinmeyer, A.4
Zugel, U.5
Bikle, D.D.6
Gallo, R.L.7
-
23
-
-
0033614417
-
Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex
-
Rachez C, Lemon BD, Suldan Z, Bromleigh V, Gamble M, Naar AM, Erdjument-Bromage H, Tempst P, Freedman LP (1999) Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex. Nature (Lond) 398:824-828
-
(1999)
Nature (Lond)
, vol.398
, pp. 824-828
-
-
Rachez, C.1
Lemon, B.D.2
Suldan, Z.3
Bromleigh, V.4
Gamble, M.5
Naar, A.M.6
Erdjument-Bromage, H.7
Tempst, P.8
Freedman, L.P.9
-
24
-
-
0034034013
-
The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes
-
Rachez C, Gamble M, Chang CP, Atkins GB, Lazar MA, Freedman LP (2000) The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes. Mol Cell Biol 20:2718-2726
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2718-2726
-
-
Rachez, C.1
Gamble, M.2
Chang, C.P.3
Atkins, G.B.4
Lazar, M.A.5
Freedman, L.P.6
-
25
-
-
0034615669
-
The SRC family of nuclear receptor coactivators
-
Leo C, Chen JD (2000) The SRC family of nuclear receptor coactivators. Gene (Amst) 245:1-11
-
(2000)
Gene (Amst)
, vol.245
, pp. 1-11
-
-
Leo, C.1
Chen, J.D.2
-
26
-
-
61749101307
-
Quantification of the vitamin D receptor-coregulator interaction
-
Teichert A, Arnold LA, Otieno S, Oda Y, Augustinaite I, Geistlinger TR, Kriwacki RW, Guy RK, Bikle DD (2009) Quantification of the vitamin D receptor-coregulator interaction. Biochemistry 48:1454-1461
-
(2009)
Biochemistry
, vol.48
, pp. 1454-1461
-
-
Teichert, A.1
Arnold, L.A.2
Otieno, S.3
Oda, Y.4
Augustinaite, I.5
Geistlinger, T.R.6
Kriwacki, R.W.7
Guy, R.K.8
Bikle, D.D.9
-
27
-
-
1642387079
-
Selective recognition of distinct classes of coactivators by a ligand-inducible activation domain
-
Acevedo ML, Lee KC, Stender JD, Katzenellenbogen BS, Kraus WL (2004) Selective recognition of distinct classes of coactivators by a ligand-inducible activation domain. Mol Cell 13:725-738
-
(2004)
Mol Cell
, vol.13
, pp. 725-738
-
-
Acevedo, M.L.1
Lee, K.C.2
Stender, J.D.3
Katzenellenbogen, B.S.4
Kraus, W.L.5
-
28
-
-
0037371241
-
New insights into the mechanisms of vitamin D action
-
Christakos S, Dhawan P, Liu Y, Peng X, Porta A (2003) New insights into the mechanisms of vitamin D action. J Cell Biochem 88:695-705
-
(2003)
J Cell Biochem
, vol.88
, pp. 695-705
-
-
Christakos, S.1
Dhawan, P.2
Liu, Y.3
Peng, X.4
Porta, A.5
-
29
-
-
0034603725
-
Mechanisms of gene regulation by vitamin D(3) receptor: A network of coactivator interactions
-
Rachez C, Freedman LP (2000) Mechanisms of gene regulation by vitamin D(3) receptor: a network of coactivator interactions. Gene (Amst) 246:9-21
-
(2000)
Gene (Amst)
, vol.246
, pp. 9-21
-
-
Rachez, C.1
Freedman, L.P.2
-
30
-
-
38449107253
-
1,25-Dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex
-
Carvallo L, Henriquez B, Paredes R, Olate J, Onate S, Van Wijnen AJ, Lian JB, Stein G, Stein JL, Montecino M (2008) 1,25-Dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex. J Cell Physiol 214:740-749
-
(2008)
J Cell Physiol
, vol.214
, pp. 740-749
-
-
Carvallo, L.1
Henriquez, B.2
Paredes, R.3
Olate, J.4
Onate, S.5
Van Wijnen, A.J.6
Lian, J.B.7
Stein, G.8
Stein, J.L.9
Montecino, M.10
-
32
-
-
27544441670
-
Mechanisms for the selective action of vitamin D analogs
-
Bouillon R, Verlinden L, Eelen G, De Clercq PV M, Mathieu C, Verstuyf A (2005) Mechanisms for the selective action of vitamin D analogs. J Steroid Biochem Mol Biol 97:21-30
-
(2005)
J Steroid Biochem Mol Biol
, vol.97
, pp. 21-30
-
-
Bouillon, R.1
Verlinden, L.2
Eelen, G.3
De Clercq, P.V.M.4
Mathieu, C.5
Verstuyf, A.6
-
33
-
-
0036019471
-
Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205
-
Maeda Y, Rachez C, Hawel IL, Byus CV, Freedman LP, Sladek FM (2002) Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205. Mol Endocrinol 16:1502-1510
-
(2002)
Mol Endocrinol
, vol.16
, pp. 1502-1510
-
-
Maeda, Y.1
Rachez, C.2
Hawel, I.L.3
Byus, C.V.4
Freedman, L.P.5
Sladek, F.M.6
-
34
-
-
0037302109
-
Evidence for tissue- and cell-type selective activation of the vitamin D receptor by Ro-26-9228, a noncalcemic analog of vitamin D3
-
Peleg S, Ismail A, Uskokovic M, Avnur Z (2003) Evidence for tissue- and cell-type selective activation of the vitamin D receptor by Ro-26-9228, a noncalcemic analog of vitamin D3. J Cell Biochem 88:267-273
-
(2003)
J Cell Biochem
, vol.88
, pp. 267-273
-
-
Peleg, S.1
Ismail, A.2
Uskokovic, M.3
Avnur, Z.4
-
35
-
-
1442323632
-
Wnt signaling through the beta-catenin pathway is sufficient to maintain, but not restore, anagen-phase characteristics of dermal papilla cells
-
Shimizu H, Morgan BA (2004) Wnt signaling through the beta-catenin pathway is sufficient to maintain, but not restore, anagen-phase characteristics of dermal papilla cells. J Invest Dermatol 122:239-245
-
(2004)
J Invest Dermatol
, vol.122
, pp. 239-245
-
-
Shimizu, H.1
Morgan, B.A.2
-
36
-
-
0034657419
-
Wnt signaling maintains the hair-inducing activity of the dermal papilla
-
Kishimoto J, Burgeson RE, Morgan BA (2000) Wnt signaling maintains the hair-inducing activity of the dermal papilla. Genes Dev 14:1181-1185
-
(2000)
Genes Dev
, vol.14
, pp. 1181-1185
-
-
Kishimoto, J.1
Burgeson, R.E.2
Morgan, B.A.3
-
37
-
-
1842529559
-
Capturing and profiling adult hair follicle stem cells
-
Morris RJ, Liu Y, Marles L, Yang Z, Trempus C, Li S, Lin JS, Sawicki JA, Cotsarelis G (2004) Capturing and profiling adult hair follicle stem cells. Nat Biotechnol 22:411-417
-
(2004)
Nat Biotechnol
, vol.22
, pp. 411-417
-
-
Morris, R.J.1
Liu, Y.2
Marles, L.3
Yang, Z.4
Trempus, C.5
Li, S.6
Lin, J.S.7
Sawicki, J.A.8
Cotsarelis, G.9
-
38
-
-
0344837423
-
K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath- specific type II epithelial keratins of the human hair follicle
-
Langbein L, Rogers MA, Praetzel S, Winter H, Schweizer J (2003) K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath-specific type II epithelial keratins of the human hair follicle. J Invest Dermatol 120:512-522
-
(2003)
J Invest Dermatol
, vol.120
, pp. 512-522
-
-
Langbein, L.1
Rogers, M.A.2
Praetzel, S.3
Winter, H.4
Schweizer, J.5
-
39
-
-
0029167307
-
Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate
-
Zhou P, Byrne C, Jacobs J, Fuchs E (1995) Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev 9:700-713
-
(1995)
Genes Dev
, vol.9
, pp. 700-713
-
-
Zhou, P.1
Byrne, C.2
Jacobs, J.3
Fuchs, E.4
-
40
-
-
84943209669
-
Calcitriol-resistant rickets with alopecia
-
Hochberg Z, Gilhar A, Haim S, Friedman-Birnbaum R, Levy J, Benderly A (1985) Calcitriol-resistant rickets with alopecia. Arch Dermatol 121:646-647
-
(1985)
Arch Dermatol
, vol.121
, pp. 646-647
-
-
Hochberg, Z.1
Gilhar, A.2
Haim, S.3
Friedman-Birnbaum, R.4
Levy, J.5
Benderly, A.6
-
41
-
-
0022501061
-
Analysis of the relation between alopecia and resistance to 1,25-dihydroxyvitamin D
-
Marx SJ, Bliziotes MM, Nanes M (1986) Analysis of the relation between alopecia and resistance to 1,25-dihydroxyvitamin D. Clin Endocrinol (Oxf) 25:373-381
-
(1986)
Clin Endocrinol (Oxf)
, vol.25
, pp. 373-381
-
-
Marx, S.J.1
Bliziotes, M.M.2
Nanes, M.3
-
42
-
-
0030763857
-
Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning
-
Yoshizawa T, Handa Y, Uematsu Y, Takeda S, Sekine K, Yoshihara Y, Kawakami T, Arioka K, Sato H, Uchiyama Y, Masushige S, Fukamizu A, Matsumoto T, Kato S (1997) Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nat Genet 16:391-396
-
(1997)
Nat Genet
, vol.16
, pp. 391-396
-
-
Yoshizawa, T.1
Handa, Y.2
Uematsu, Y.3
Takeda, S.4
Sekine, K.5
Yoshihara, Y.6
Kawakami, T.7
Arioka, K.8
Sato, H.9
Uchiyama, Y.10
Masushige, S.11
Fukamizu, A.12
Matsumoto, T.13
Kato, S.14
-
43
-
-
0034455280
-
Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice
-
Sakai Y, Demay MB (2000) Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice. Endocrinology 141:2043-2049
-
(2000)
Endocrinology
, vol.141
, pp. 2043-2049
-
-
Sakai, Y.1
Demay, M.B.2
-
44
-
-
0036226321
-
Targeted expression of human vitamin d receptor in the skin promotes the initiation of the postnatal hair follicle cycle and rescues the alopecia in vitamin D receptor null mice
-
Kong J, Li XJ, Gavin D, Jiang Y, Li YC (2002) Targeted expression of human vitamin d receptor in the skin promotes the initiation of the postnatal hair follicle cycle and rescues the alopecia in vitamin D receptor null mice. J Invest Dermatol 118:631-638
-
(2002)
J Invest Dermatol
, vol.118
, pp. 631-638
-
-
Kong, J.1
Li, X.J.2
Gavin, D.3
Jiang, Y.4
Li, Y.C.5
-
45
-
-
0035213293
-
Targeting expression of the human vitamin D receptor to the keratinocytes of vitamin D receptor null mice prevents alopecia
-
Chen CH, Sakai Y, Demay MB (2001) Targeting expression of the human vitamin D receptor to the keratinocytes of vitamin D receptor null mice prevents alopecia. Endocrinology 142:5386-5389
-
(2001)
Endocrinology
, vol.142
, pp. 5386-5389
-
-
Chen, C.H.1
Sakai, Y.2
Demay, M.B.3
-
46
-
-
0000524953
-
Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice
-
Li YC, Amling M, Pirro AE, Priemel M, Meuse J, Baron R, Delling G, Demay MB (1998) Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice. Endocrinology 139:4391-4396
-
(1998)
Endocrinology
, vol.139
, pp. 4391-4396
-
-
Li, Y.C.1
Amling, M.2
Pirro, A.E.3
Priemel, M.4
Meuse, J.5
Baron, R.6
Delling, G.7
Demay, M.B.8
-
47
-
-
0033017297
-
The role of the hairless (hr) gene in the regulation of hair follicle catagen transformation
-
Panteleyev AA, Botchkareva NV, Sundberg JP, Christiano AM, Paus R (1999) The role of the hairless (hr) gene in the regulation of hair follicle catagen transformation. Am J Pathol 155:159-171
-
(1999)
Am J Pathol
, vol.155
, pp. 159-171
-
-
Panteleyev, A.A.1
Botchkareva, N.V.2
Sundberg, J.P.3
Christiano, A.M.4
Paus, R.5
-
48
-
-
0034800098
-
Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene
-
Miller J, Djabali K, Chen T, Liu Y, Ioffreda M, Lyle S, Christiano AM, Holick M, Cotsarelis G (2001) Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene. J Invest Dermatol 117:612-617
-
(2001)
J Invest Dermatol
, vol.117
, pp. 612-617
-
-
Miller, J.1
Djabali, K.2
Chen, T.3
Liu, Y.4
Ioffreda, M.5
Lyle, S.6
Christiano, A.M.7
Holick, M.8
Cotsarelis, G.9
-
49
-
-
6844265562
-
Alopecia universalis associated with a mutation in the human hairless gene
-
Ahmad W, Faiyaz ul Haque M, Brancolini V, Tsou HC, ul Haque S, Lam H, Aita VM, Owen J, deBlaquiere M, Frank J, Cserhalmi-Friedman PB, Leask A, McGrath JA, Peacocke M, Ahmad M, Ott J, Christiano AM (1998) Alopecia universalis associated with a mutation in the human hairless gene. Science 279:720-724
-
(1998)
Science
, vol.279
, pp. 720-724
-
-
Ahmad, W.1
Faiyaz Ul Haque, M.2
Brancolini, V.3
Tsou, H.C.4
Ul Haque, S.5
Lam, H.6
Aita, V.M.7
Owen, J.8
De Blaquiere, M.9
Frank, J.10
Cserhalmi-Friedman, P.B.11
Leask, A.12
McGrath, J.A.13
Peacocke, M.14
Ahmad, M.15
Ott, J.16
Christiano, A.M.17
-
50
-
-
0036178229
-
Molecular mechanisms regulating hair follicle development
-
Millar SE (2002) Molecular mechanisms regulating hair follicle development. J Invest Dermatol 118:216-225
-
(2002)
J Invest Dermatol
, vol.118
, pp. 216-225
-
-
Millar, S.E.1
-
51
-
-
0035134022
-
Controls of hair follicle cycling
-
Stenn KS, Paus R (2001) Controls of hair follicle cycling. Physiol Rev 81:449-494
-
(2001)
Physiol Rev
, vol.81
, pp. 449-494
-
-
Stenn, K.S.1
Paus, R.2
-
52
-
-
0035907041
-
Beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
-
Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W (2001) beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105:533-545
-
(2001)
Cell
, vol.105
, pp. 533-545
-
-
Huelsken, J.1
Vogel, R.2
Erdmann, B.3
Cotsarelis, G.4
Birchmeier, W.5
-
53
-
-
0037157837
-
A developmental conundrum: A stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells
-
DasGupta R, Rhee H, Fuchs E (2002) A developmental conundrum: a stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells. J Cell Biol 158:331-344
-
(2002)
J Cell Biol
, vol.158
, pp. 331-344
-
-
DasGupta, R.1
Rhee, H.2
Fuchs, E.3
-
55
-
-
0032953901
-
Essential role for sonic hedgehog during hair follicle morphogenesis
-
Chiang C, Swan RZ, Grachtchouk M, Bolinger M, Litingtung Y, Robertson EK, Cooper MK, Gaffield W, Westphal H, Beachy PA, Dlugosz AA (1999) Essential role for sonic hedgehog during hair follicle morphogenesis. Dev Biol 205:1-9
-
(1999)
Dev Biol
, vol.205
, pp. 1-9
-
-
Chiang, C.1
Swan, R.Z.2
Grachtchouk, M.3
Bolinger, M.4
Litingtung, Y.5
Robertson, E.K.6
Cooper, M.K.7
Gaffield, W.8
Westphal, H.9
Beachy, P.A.10
Dlugosz, A.A.11
-
57
-
-
3242673144
-
Expression of Frizzled genes in developing and postnatal hair follicles
-
Reddy ST, Andl T, Lu MM, Morrisey EE, Millar SE (2004) Expression of Frizzled genes in developing and postnatal hair follicles. J Invest Dermatol 123:275-282
-
(2004)
J Invest Dermatol
, vol.123
, pp. 275-282
-
-
Reddy, S.T.1
Andl, T.2
Lu, M.M.3
Morrisey, E.E.4
Millar, S.E.5
-
58
-
-
0347481364
-
Trans-repression of beta-catenin activity by nuclear receptors
-
Shah S, Hecht A, Pestell R, Byers SW (2003) Trans-repression of beta-catenin activity by nuclear receptors. J Biol Chem 278:48137-48145
-
(2003)
J Biol Chem
, vol.278
, pp. 48137-48145
-
-
Shah, S.1
Hecht, A.2
Pestell, R.3
Byers, S.W.4
-
59
-
-
33644850904
-
The molecular basis of vitamin D receptor and beta-catenin crossregulation
-
Shah S, Islam MN, Dakshanamurthy S, Rizvi I, Rao M, Herrell R, Zinser G, Valrance M, Aranda A, Moras D, Norman A, Welsh J, Byers SW (2006) The molecular basis of vitamin D receptor and beta-catenin crossregulation. Mol Cell 21:799-809
-
(2006)
Mol Cell
, vol.21
, pp. 799-809
-
-
Shah, S.1
Islam, M.N.2
Dakshanamurthy, S.3
Rizvi, I.4
Rao, M.5
Herrell, R.6
Zinser, G.7
Valrance, M.8
Aranda, A.9
Moras, D.10
Norman, A.11
Welsh, J.12
Byers, S.W.13
-
60
-
-
18344389705
-
Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling
-
Palmer HG, Gonzalez-Sancho JM, Espada J, Berciano MT, Puig I, Baulida J, Quintanilla M, Cano A, de Herreros AG, Lafarga M, Munoz A (2001) Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J Cell Biol 154:369-387
-
(2001)
J Cell Biol
, vol.154
, pp. 369-387
-
-
Palmer, H.G.1
Gonzalez-Sancho, J.M.2
Espada, J.3
Berciano, M.T.4
Puig, I.5
Baulida, J.6
Quintanilla, M.7
Cano, A.8
De Herreros, A.G.9
Lafarga, M.10
Munoz, A.11
-
61
-
-
0035121438
-
Hairless is translocated to the nucleus via a novel bipartite nuclear localization signal and is associated with the nuclear matrix
-
Djabali K, Aita VM, Christiano AM (2001) Hairless is translocated to the nucleus via a novel bipartite nuclear localization signal and is associated with the nuclear matrix. J Cell Sci 114:367-376
-
(2001)
J Cell Sci
, vol.114
, pp. 367-376
-
-
Djabali, K.1
Aita, V.M.2
Christiano, A.M.3
-
62
-
-
0030737945
-
The product of a thyroid hormone-responsive gene interacts with thyroid hormone receptors
-
Thompson CC, Bottcher MC (1997) The product of a thyroid hormone-responsive gene interacts with thyroid hormone receptors. Proc Natl Acad Sci USA 94:8527-8532
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8527-8532
-
-
Thompson, C.C.1
Bottcher, M.C.2
-
63
-
-
2442445464
-
The hairless promoter is differentially regulated by thyroid hormone in keratinocytes and neuroblastoma cells
-
Engelhard A, Christiano AM (2004) The hairless promoter is differentially regulated by thyroid hormone in keratinocytes and neuroblastoma cells. Exp Dermatol 13:257-264
-
(2004)
Exp Dermatol
, vol.13
, pp. 257-264
-
-
Engelhard, A.1
Christiano, A.M.2
-
64
-
-
29344450418
-
Hairless suppresses vitamin D receptor transactivation in human keratinocytes
-
Xie Z, Chang S, Oda Y, Bikle DD (2006) Hairless suppresses vitamin D receptor transactivation in human keratinocytes. Endocrinology 147:314-323
-
(2006)
Endocrinology
, vol.147
, pp. 314-323
-
-
Xie, Z.1
Chang, S.2
Oda, Y.3
Bikle, D.D.4
-
65
-
-
0141961566
-
Physical and functional interaction between the vitamin D receptor and hairless core-pressor, two proteins required for hair cycling
-
Hsieh JC, Sisk JM, Jurutka PW, Haussler CA, Slater SA, Haussler MR, Thompson CC (2003) Physical and functional interaction between the vitamin D receptor and hairless core-pressor, two proteins required for hair cycling. J Biol Chem 278:38665-38674
-
(2003)
J Biol Chem
, vol.278
, pp. 38665-38674
-
-
Hsieh, J.C.1
Sisk, J.M.2
Jurutka, P.W.3
Haussler, C.A.4
Slater, S.A.5
Haussler, M.R.6
Thompson, C.C.7
-
66
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW (1998) Identification of c-MYC as a target of the APC pathway. Science 281:1509-1512
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
Da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
67
-
-
34247869640
-
The recruitment of phosphatidylinositol 3-kinase to the E-cadherin-catenin complex at the plasma membrane is required for calcium-induced phospholipase C-gamma1 activation and human keratinocyte differentiation
-
Xie Z, Bikle DD (2007) The recruitment of phosphatidylinositol 3-kinase to the E-cadherin-catenin complex at the plasma membrane is required for calcium-induced phospholipase C-gamma1 activation and human keratinocyte differentiation. J Biol Chem 282:8695-8703
-
(2007)
J Biol Chem
, vol.282
, pp. 8695-8703
-
-
Xie, Z.1
Bikle, D.D.2
-
68
-
-
12544252343
-
Beta-Catenin: A pivot between cell adhesion and Wnt signalling
-
Bienz M (2005) beta-Catenin: a pivot between cell adhesion and Wnt signalling. Curr Biol 15:R64-R67
-
(2005)
Curr Biol
, vol.15
-
-
Bienz, M.1
-
69
-
-
0032953231
-
A common human skin tumour is caused by activating mutations in beta-catenin
-
Chan EF, Gat U, McNiff JM, Fuchs E (1999) A common human skin tumour is caused by activating mutations in beta-catenin. Nat Genet 21:410-413
-
(1999)
Nat Genet
, vol.21
, pp. 410-413
-
-
Chan, E.F.1
Gat, U.2
McNiff, J.M.3
Fuchs, E.4
-
70
-
-
0032567078
-
De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
-
Gat U, DasGupta R, Degenstein L, Fuchs E (1998) De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 95:605-614
-
(1998)
Cell
, vol.95
, pp. 605-614
-
-
Gat, U.1
DasGupta, R.2
Degenstein, L.3
Fuchs, E.4
-
71
-
-
30444456684
-
Beta-Catenin mutation and its nuclear localization are confirmed to be frequent causes of Wnt signaling pathway activation in pilomatricomas
-
Xia J, Urabe K, Moroi Y, Koga T, Duan H, Li Y, Furue M (2006) beta-Catenin mutation and its nuclear localization are confirmed to be frequent causes of Wnt signaling pathway activation in pilomatricomas. J Dermatol Sci 41:67-75
-
(2006)
J Dermatol Sci
, vol.41
, pp. 67-75
-
-
Xia, J.1
Urabe, K.2
Moroi, Y.3
Koga, T.4
Duan, H.5
Li, Y.6
Furue, M.7
-
72
-
-
44649160789
-
The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis
-
Palmer HG, Anjos-Afonso F, Carmeliet G, Takeda H, Watt FM (2008) The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. PLoS ONE 3:e1483
-
(2008)
PLoS ONE
, vol.3
-
-
Palmer, H.G.1
Anjos-Afonso, F.2
Carmeliet, G.3
Takeda, H.4
Watt, F.M.5
-
73
-
-
34547215387
-
Vitamin D receptor is essential for normal keratinocyte stem cell function
-
Cianferotti L, Cox M, Skorija K, Demay MB (2007) Vitamin D receptor is essential for normal keratinocyte stem cell function. Proc Natl Acad Sci USA 104:9428-9433
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 9428-9433
-
-
Cianferotti, L.1
Cox, M.2
Skorija, K.3
Demay, M.B.4
-
74
-
-
0035114558
-
Cancer statistics, 2001
-
Greenlee RT, Hill-Harmon MB, Murray T, Thun M (2001) Cancer statistics, 2001. CA Cancer J Clin 51:15-36
-
(2001)
CA Cancer J Clin
, vol.51
, pp. 15-36
-
-
Greenlee, R.T.1
Hill-Harmon, M.B.2
Murray, T.3
Thun, M.4
-
75
-
-
0024379332
-
Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light
-
Freeman SE, Hacham H, Gange RW, Maytum DJ, Sutherland JC, Sutherland BM (1989) Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light. Proc Natl Acad Sci USA 86:5605-5609
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5605-5609
-
-
Freeman, S.E.1
Hacham, H.2
Gange, R.W.3
Maytum, D.J.4
Sutherland, J.C.5
Sutherland, B.M.6
-
76
-
-
14044257121
-
Ultraviolet radiation and skin cancer: Molecular mechanisms
-
Hussein MR (2005) Ultraviolet radiation and skin cancer: molecular mechanisms. J Cutan Pathol 32:191-205
-
(2005)
J Cutan Pathol
, vol.32
, pp. 191-205
-
-
Hussein, M.R.1
-
77
-
-
14644430466
-
The role of UV induced lesions in skin carcinogenesis: An overview of oncogene and tumor suppressor gene modifications in xeroderma pigmentosum skin tumors
-
Daya-Grosjean L, Sarasin A (2005) The role of UV induced lesions in skin carcinogenesis: an overview of oncogene and tumor suppressor gene modifications in xeroderma pigmentosum skin tumors. Mutat Res 571:43-56
-
(2005)
Mutat Res
, vol.571
, pp. 43-56
-
-
Daya-Grosjean, L.1
Sarasin, A.2
-
78
-
-
0027166864
-
Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers
-
Ziegler A, Leffell DJ, Kunala S, Sharma HW, Gailani M, Simon JA, Halperin AJ, Baden HP, Shapiro PE, Bale AE, Brash DE (1993) Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proc Natl Acad Sci USA 90:4216-4220
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4216-4220
-
-
Ziegler, A.1
Leffell, D.J.2
Kunala, S.3
Sharma, H.W.4
Gailani, M.5
Simon, J.A.6
Halperin, A.J.7
Baden, H.P.8
Shapiro, P.E.9
Bale, A.E.10
Brash, D.E.11
-
79
-
-
0028596185
-
Sunburn and p53 in the onset of skin cancer
-
Ziegler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, Kimmelman J, Remington L, Jacks T, Brash DE (1994) Sunburn and p53 in the onset of skin cancer. Nature (Lond) 372:773-776
-
(1994)
Nature (Lond)
, vol.372
, pp. 773-776
-
-
Ziegler, A.1
Jonason, A.S.2
Leffell, D.J.3
Simon, J.A.4
Sharma, H.W.5
Kimmelman, J.6
Remington, L.7
Jacks, T.8
Brash, D.E.9
-
80
-
-
0025719491
-
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma
-
Brash DE, Rudolph JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, Ponten J (1991) A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 88:10124-10128
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10124-10128
-
-
Brash, D.E.1
Rudolph, J.A.2
Simon, J.A.3
Lin, A.4
McKenna, G.J.5
Baden, H.P.6
Halperin, A.J.7
Ponten, J.8
-
81
-
-
0028828208
-
Cyclin D and retinoblastoma gene product expression in actinic keratosis and cutaneous squamous cell carcinoma in relation to p53 expression
-
Bito T, Ueda M, Ahmed NU, Nagano T, Ichihashi M (1995) Cyclin D and retinoblastoma gene product expression in actinic keratosis and cutaneous squamous cell carcinoma in relation to p53 expression. J Cutan Pathol 22:427-434
-
(1995)
J Cutan Pathol
, vol.22
, pp. 427-434
-
-
Bito, T.1
Ueda, M.2
Ahmed, N.U.3
Nagano, T.4
Ichihashi, M.5
-
82
-
-
19944433687
-
Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas
-
Reifenberger J, Wolter M, Knobbe CB, Kohler B, Schonicke A, Scharwachter C, Kumar K, Blaschke B, Ruzicka T, Reifenberger G (2005) Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas. Br J Dermatol 152:43-51
-
(2005)
Br J Dermatol
, vol.152
, pp. 43-51
-
-
Reifenberger, J.1
Wolter, M.2
Knobbe, C.B.3
Kohler, B.4
Schonicke, A.5
Scharwachter, C.6
Kumar, K.7
Blaschke, B.8
Ruzicka, T.9
Reifenberger, G.10
-
83
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, Bonifas JM, Quinn AG, Myers RM, Cox DR, Epstein EH Jr, Scott MP (1996) Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272:1668-1671
-
(1996)
Science
, vol.272
, pp. 1668-1671
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
Goodrich, L.V.4
Bare, J.W.5
Bonifas, J.M.6
Quinn, A.G.7
Myers, R.M.8
Cox, D.R.9
Epstein Jr., E.H.10
Scott, M.P.11
-
84
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H, Wicking C, Zaphiropoulous PG, Gailani MR, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden AB, Gillies S, Negus K, Smyth I, Pressman C, Leffell DJ, Gerrard B, Goldstein AM, Dean M, Toftgard R, Chenevix-Trench G, Wainwright B, Bale AE (1996) Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85:841-851
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulous, P.G.3
Gailani, M.R.4
Shanley, S.5
Chidambaram, A.6
Vorechovsky, I.7
Holmberg, E.8
Unden, A.B.9
Gillies, S.10
Negus, K.11
Smyth, I.12
Pressman, C.13
Leffell, D.J.14
Gerrard, B.15
Goldstein, A.M.16
Dean, M.17
Toftgard, R.18
Chenevix-Trench, G.19
Wainwright, B.20
Bale, A.E.21
more..
-
85
-
-
0031837549
-
Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome
-
Aszterbaum M, Rothman A, Johnson RL, Fisher M, Xie J, Bonifas JM, Zhang X, Scott MP, Epstein EH Jr (1998) Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome. J Invest Dermatol 110:885-888
-
(1998)
J Invest Dermatol
, vol.110
, pp. 885-888
-
-
Aszterbaum, M.1
Rothman, A.2
Johnson, R.L.3
Fisher, M.4
Xie, J.5
Bonifas, J.M.6
Zhang, X.7
Scott, M.P.8
Epstein Jr., E.H.9
-
86
-
-
0032694528
-
Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice
-
Aszterbaum M, Epstein J, Oro A, Douglas V, LeBoit PE, Scott MP, Epstein EH Jr (1999) Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. Nat Med 5:1285-1291
-
(1999)
Nat Med
, vol.5
, pp. 1285-1291
-
-
Aszterbaum, M.1
Epstein, J.2
Oro, A.3
Douglas, V.4
LeBoit, P.E.5
Scott, M.P.6
Epstein Jr., E.H.7
-
87
-
-
0035050910
-
PTCH mutations in squamous cell carcinoma of the skin
-
DOI 10.1046/j.1523-1747.2001.01301.x
-
Ping XL, Ratner D, Zhang H, Wu XL, Zhang MJ, Chen FF, Silvers DN, Peacocke M, Tsou HC (2001) PTCH mutations in squamous cell carcinoma of the skin. J Invest Dermatol 116:614-616 (Pubitemid 32299854)
-
(2001)
Journal of Investigative Dermatology
, vol.116
, Issue.4
, pp. 614-616
-
-
Ping, X.L.1
Ratner, D.2
Zhang, H.3
Wu, X.L.4
Zhang, M.J.5
Chen, F.F.6
Silvers, D.N.7
Peacocke, M.8
Tsou, H.C.9
-
88
-
-
0036963428
-
Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis
-
Zinser GM, Sundberg JP, Welsh J (2002) Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis. Carcinogenesis (Oxf) 23:2103-2109
-
(2002)
Carcinogenesis (Oxf)
, vol.23
, pp. 2103-2109
-
-
Zinser, G.M.1
Sundberg, J.P.2
Welsh, J.3
-
89
-
-
34247251953
-
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes
-
Indra AK, Castaneda E, Antal MC, Jiang M, Messaddeq N, Meng X, Loehr CV, Gariglio P, Kato S, Wahli W, Desvergne B, Metzger D, Chambon P (2007) Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes. J Invest Dermatol 127:1250-1260
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1250-1260
-
-
Indra, A.K.1
Castaneda, E.2
Antal, M.C.3
Jiang, M.4
Messaddeq, N.5
Meng, X.6
Loehr, C.V.7
Gariglio, P.8
Kato, S.9
Wahli, W.10
Desvergne, B.11
Metzger, D.12
Chambon, P.13
-
90
-
-
51749113106
-
Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis
-
Ellison TI, Smith MK, Gilliam AC, Macdonald PN (2008) Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis. J Invest Dermatol 128:2508-2517
-
(2008)
J Invest Dermatol
, vol.128
, pp. 2508-2517
-
-
Ellison, T.I.1
Smith, M.K.2
Gilliam, A.C.3
Macdonald, P.N.4
-
91
-
-
1442303112
-
The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells
-
Regl G, Kasper M, Schnidar H, Eichberger T, Neill GW, Ikram MS, Quinn AG, Philpott MP, Frischauf AM, Aberger F (2004) The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells. Oncogene 23:1263-1274
-
(2004)
Oncogene
, vol.23
, pp. 1263-1274
-
-
Regl, G.1
Kasper, M.2
Schnidar, H.3
Eichberger, T.4
Neill, G.W.5
Ikram, M.S.6
Quinn, A.G.7
Philpott, M.P.8
Frischauf, A.M.9
Aberger, F.10
-
92
-
-
31744450041
-
Negative regulation of Gli1 and Gli2 activator function by suppressor of fused through multiple mechanisms
-
Barnfield PC, Zhang X, Thanabalasingham V, Yoshida M, Hui CC (2005) Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms. Differentiation 73:397-405
-
(2005)
Differentiation
, vol.73
, pp. 397-405
-
-
Barnfield, P.C.1
Zhang, X.2
Thanabalasingham, V.3
Yoshida, M.4
Hui, C.C.5
-
93
-
-
33847138972
-
Promotion of hras-induced squamous carcinomas by a polymorphic variant of the patched gene in FVB mice
-
Wakabayashi Y, Mao JH, Brown K, Girardi M, Balmain A (2007) Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice. Nature (Lond) 445:761-765
-
(2007)
Nature (Lond)
, vol.445
, pp. 761-765
-
-
Wakabayashi, Y.1
Mao, J.H.2
Brown, K.3
Girardi, M.4
Balmain, A.5
-
94
-
-
33747332214
-
Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion
-
Bijlsma MF, Spek CA, Zivkovic D, van de Water S, Rezaee F, Peppelenbosch MP (2006) Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion. PLoS Biol 4:e232
-
(2006)
PLoS Biol
, vol.4
-
-
Bijlsma, M.F.1
Spek, C.A.2
Zivkovic, D.3
Van De Water, S.4
Rezaee, F.5
Peppelenbosch, M.P.6
-
95
-
-
31744451535
-
Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian hedgehog signaling pathway
-
Svard J, Heby-Henricson K, Persson-Lek M, Rozell B, Lauth M, Bergstrom A, Ericson J, Toftgard R, Teglund S (2006) Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway. Dev Cell 10:187-197
-
(2006)
Dev Cell
, vol.10
, pp. 187-197
-
-
Svard, J.1
Heby-Henricson, K.2
Persson-Lek, M.3
Rozell, B.4
Lauth, M.5
Bergstrom, A.6
Ericson, J.7
Toftgard, R.8
Teglund, S.9
-
96
-
-
7444247429
-
Activation of the BCL2 promoter in response to hedgehog/GLI signal transduction is predominantly mediated by GLI2
-
Regl G, Kasper M, Schnidar H, Eichberger T, Neill GW, Philpott MP, Esterbauer H, Hauser-Kronberger C, Frischauf AM, Aberger F (2004) Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2. Cancer Res 64:7724-7731
-
(2004)
Cancer Res
, vol.64
, pp. 7724-7731
-
-
Regl, G.1
Kasper, M.2
Schnidar, H.3
Eichberger, T.4
Neill, G.W.5
Philpott, M.P.6
Esterbauer, H.7
Hauser-Kronberger, C.8
Frischauf, A.M.9
Aberger, F.10
-
97
-
-
0037103909
-
Human GLI2 and GLI1 are part of a positive feedback mechanism in basal cell carcinoma
-
Regl G, Neill GW, Eichberger T, Kasper M, Ikram MS, Koller J, Hintner H, Quinn AG, Frischauf AM, Aberger F (2002) Human GLI2 and GLI1 are part of a positive feedback mechanism in basal cell carcinoma. Oncogene 21:5529-5539
-
(2002)
Oncogene
, vol.21
, pp. 5529-5539
-
-
Regl, G.1
Neill, G.W.2
Eichberger, T.3
Kasper, M.4
Ikram, M.S.5
Koller, J.6
Hintner, H.7
Quinn, A.G.8
Frischauf, A.M.9
Aberger, F.10
-
98
-
-
0034091805
-
Basal cell carcinomas in mice over-expressing Gli2 in skin
-
Grachtchouk M, Mo R, Yu S, Zhang X, Sasaki H, Hui CC, Dlugosz AA (2000) Basal cell carcinomas in mice over-expressing Gli2 in skin. Nat Genet 24:216-217
-
(2000)
Nat Genet
, vol.24
, pp. 216-217
-
-
Grachtchouk, M.1
Mo, R.2
Yu, S.3
Zhang, X.4
Sasaki, H.5
Hui, C.C.6
Dlugosz, A.A.7
-
99
-
-
0034724219
-
Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI1
-
Nilsson M, Unden AB, Krause D, Malmqwist U, Raza K, Zaphiropoulos PG, Toftgard R (2000) Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI1. Proc Natl Acad Sci USA 97:3438-3443
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3438-3443
-
-
Nilsson, M.1
Unden, A.B.2
Krause, D.3
Malmqwist, U.4
Raza, K.5
Zaphiropoulos, P.G.6
Toftgard, R.7
-
100
-
-
0030955557
-
Basal cell carcinomas in mice overexpressing sonic hedgehog
-
Oro AE, Higgins KM, Hu Z, Bonifas JM, Epstein EH Jr, Scott MP (1997) Basal cell carcinomas in mice overexpressing sonic hedgehog. Science 276:817-821
-
(1997)
Science
, vol.276
, pp. 817-821
-
-
Oro, A.E.1
Higgins, K.M.2
Hu, Z.3
Bonifas, J.M.4
Epstein Jr., E.H.5
Scott, M.P.6
-
101
-
-
0030802458
-
Induction of basal cell carcinoma features in transgenic human skin expressing sonic hedgehog
-
Fan H, Oro AE, Scott MP, Khavari PA (1997) Induction of basal cell carcinoma features in transgenic human skin expressing sonic hedgehog. Nat Med 3:788-792
-
(1997)
Nat Med
, vol.3
, pp. 788-792
-
-
Fan, H.1
Oro, A.E.2
Scott, M.P.3
Khavari, P.A.4
-
102
-
-
0032693930
-
Expression of sonic hedgehog signal transducers, patched and smoothened, in human basal cell carcinoma
-
Tojo M, Mori T, Kiyosawa H, Honma Y, Tanno Y, Kanazawa KY, Yokoya S, Kaneko F, Wanaka A (1999) Expression of sonic hedgehog signal transducers, patched and smoothened, in human basal cell carcinoma. Pathol Int 49:687-694
-
(1999)
Pathol Int
, vol.49
, pp. 687-694
-
-
Tojo, M.1
Mori, T.2
Kiyosawa, H.3
Honma, Y.4
Tanno, Y.5
Kanazawa, K.Y.6
Yokoya, S.7
Kaneko, F.8
Wanaka, A.9
-
103
-
-
0035001278
-
Activation of expression of hedgehog target genes in basal cell carcinomas
-
Bonifas JM, Pennypacker S, Chuang PT, McMahon AP, Williams M, Rosenthal A, De Sauvage FJ, Epstein EH Jr (2001) Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol 116:739-742
-
(2001)
J Invest Dermatol
, vol.116
, pp. 739-742
-
-
Bonifas, J.M.1
Pennypacker, S.2
Chuang, P.T.3
McMahon, A.P.4
Williams, M.5
Rosenthal, A.6
De Sauvage, F.J.7
Epstein Jr., E.H.8
-
104
-
-
2442423841
-
FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma
-
Eichberger T, Regl G, Ikram MS, Neill GW, Philpott MP, Aberger F, Frischauf AM (2004) FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma. J Invest Dermatol 122:1180-1187
-
(2004)
J Invest Dermatol
, vol.122
, pp. 1180-1187
-
-
Eichberger, T.1
Regl, G.2
Ikram, M.S.3
Neill, G.W.4
Philpott, M.P.5
Aberger, F.6
Frischauf, A.M.7
-
105
-
-
27644595302
-
Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes
-
Wang TT, Tavera-Mendoza LE, Laperriere D, Libby E, MacLeod NB, Nagai Y, Bourdeau V, Konstorum A, Lallemant B, Zhang R, Mader S, White JH (2005) Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol 19:2685-2695
-
(2005)
Mol Endocrinol
, vol.19
, pp. 2685-2695
-
-
Wang, T.T.1
Tavera-Mendoza, L.E.2
Laperriere, D.3
Libby, E.4
MacLeod, N.B.5
Nagai, Y.6
Bourdeau, V.7
Konstorum, A.8
Lallemant, B.9
Zhang, R.10
Mader, S.11
White, J.H.12
-
106
-
-
4043153462
-
Nuclear beta-catenin in basal cell carcinoma correlates with increased proliferation
-
Saldanha G, Ghura V, Potter L, Fletcher A (2004) Nuclear beta-catenin in basal cell carcinoma correlates with increased proliferation. Br J Dermatol 151:157-164
-
(2004)
Br J Dermatol
, vol.151
, pp. 157-164
-
-
Saldanha, G.1
Ghura, V.2
Potter, L.3
Fletcher, A.4
-
107
-
-
33847779642
-
Wnt signaling interacts with Shh to regulate taste papilla development
-
Iwatsuki K, Liu HX, Gronder A, Singer MA, Lane TF, Grosschedl R, Mistretta CM, Margolskee RF (2007) Wnt signaling interacts with Shh to regulate taste papilla development. Proc Natl Acad Sci USA 104:2253-2258
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2253-2258
-
-
Iwatsuki, K.1
Liu, H.X.2
Gronder, A.3
Singer, M.A.4
Lane, T.F.5
Grosschedl, R.6
Mistretta, C.M.7
Margolskee, R.F.8
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