A highly convergent synthesis of 2-phenyl quinoline as dual antagonists for NK2 and NK3 receptors

Synthetic Communications

Volumn 35, Issue 24, 2005, Pages 3105-3112

  Yan, Hongxing ^a   Kerns, Jeffrey K ^a   Jin, Qi ^a   Zhu, Chongjie ^a   Barnette, Mary S ^a   Callahan, James F ^a   Hay, Douglas W P ^a   Jolivette, Larry J ^a   Luttmann, Mark A ^a   Sarau, Henry M ^a   Ward, Keith W ^a   Widdowson, Katherine L ^a   Wan, Zehong ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Array approach; Convergent systhesis; COPD; NK2; NK3; Quinoline

Indexed keywords

6 FLUORO 2 PHENYL 3 (3 OXOPIPERAZIN 1 YLMETHYL)QUINOLINE 4 CARBOXYLIC ACID (1 CYCLOHEXYLETHYL)AMIDE; NEUROKININ 2 RECEPTOR; NEUROKININ 2 RECEPTOR ANTAGONIST; NEUROKININ 3 RECEPTOR; NEUROKININ 3 RECEPTOR ANTAGONIST; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION; TECHNIQUE;

EID: 28844452946     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910500281234     Document Type: Article

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