Edaravone, a known free radical scavenger, enhances X-ray-induced apoptosis at low concentrations

Cancer Letters

Volumn 293, Issue 1, 2010, Pages 52-57

  Sasano, N ^a,b   Enomoto, A ^b   Hosoi, Y ^c   Katsumura, Y ^d   Matsumoto, Y ^e   Morita, A ^f   Shiraishi, K ^a   Miyagawa, K ^b   Igaki, H ^a   Nakagawa, K ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e Tokyo Institute of Technology ^*  (Japan)

^f TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Apoptosis; Edaravone; P53; Radiosensitizer

Indexed keywords

NORPHENAZONE; PROTEIN P53; PUMA PROTEIN; REACTIVE OXYGEN METABOLITE; SERINE; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIATION DOSE; RADIOSENSITIZATION; SIGNAL TRANSDUCTION; UPREGULATION; X IRRADIATION; X RAY;

ANTIPYRINE; APOPTOSIS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HUMANS; LEUKEMIA, T-CELL; RADIATION-SENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; X-RAYS;

EID: 77952426123     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.12.020     Document Type: Article

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