Decreased reverse cholesterol transport from tangier disease fibroblasts: Acceptor specificity and effect of brefeldin on lipid efflux

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 9, 1997, Pages 1813-1821

  Remaley, A T ^a   Schumacher, U K ^b   Stonik, J A ^b   Farsi, B D ^b   Nazih, H ^b   Brewer Jr , H B ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Atherosclerosis; Brefeldin; Cholesterol; High density lipoprotein; Tangier disease

Indexed keywords

BREFELDIN A;

ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LIPID ANALYSIS; LIPID TRANSPORT; PHOSPHOLIPID TRANSFER; PRIORITY JOURNAL; SKIN FIBROBLAST; TANGIER DISEASE;

EID: 0030852447     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.9.1813     Document Type: Article

References (19)

1. Fredrickson DS, Atrocchi PH, Avioli LV, Goodman DS, Goodman HC. Tangier disease. Ann Intern Med. 1961;55:1016-1031.
2. Assman G, Von Eckardstein A, Brewer HB. Familial high density lipoprotein deficiency: Tangier disease. In: Scriver CR, Beaudet AL, Sy WS, Valle D, eds. The Metabolic and Molecular Bases of Inherited Disease. New York: McGraw Hill; 1995:2053-2072.
3. Schmitz G, Bruning T, Williamson E, Nowicka G. The role of HDL in reverse cholesterol transport and its disturbances in Tangier disease and HDL deficiency with xanthomas. Eur Heart J. 1990;11:197-121.
4. Serfaty-Lacrosniere C, Civeira F, Lanzberg A, Isaia P, Berg J, Janus ED, Smith MP, Pritchard PH, Frohlich J, Lees RS, Barnard GF, Ordovas JM, Schaefer EJ. Homozygous Tangier disease and cardiovascular disease. Atherosclerosis. 1994;107:85-98.
5. Law SW, Brewer HB Jr. Tangier disease: the complete amino acid sequence for proapo-AI. J Biol Chem. 1985;260:12810-12814.
6. Schaefer EJ, Anderson DW, Zech LA, Lindgren FT, Bronzert TB, Rubalcaba EA, Brewer HB. Metabolism of high density lipoprotein subfractions and constituents in Tangier disease following the infusion of high density lipoproteins. J Lipid Res. 1981;22:217-228.
7. Rogler G, Trumbach B, Klima B, Lackner KJ, Schmitz G. HDL-mediated efflux of intracellular cholesterol is impaired in fibroblasts from Tangier disease patients. Arterioscler Thromb Vasc Biol. 1995;15:683-690.
8. Drobnik W, Mollers C, Resnik T, Schmitz G. Activation of phosphatidylinositol-specific phospholipase C in response to HDL3 and HDL is markedly reduced in cultured fibroblasts from Tangier patients. Arterioscler Thromb Vasc Biol. 1995;15:1369-1377.
9. Walter M, Gerdes U, Seedorf U, Assmann G. The high density lipoprotein and apolipoprotein A-I induced mobilization of cellular cholesterol is impaired in fibroblast from tangier disease subjects. Biochem Biophys Res Commun. 1994;205:850-856.
10. Schmitz G, Assmann G, Robenek H, Brennhausen B. Tangier disease: a disorder of intracellular membrane traffic. Proc Natl Acad Sci U S A. 1985;82:6305-6309.
11. Francis GA, Knopp RH, Qram JF. Defective removal of cellular choleslerol and phospholipids by apolipoprotein A-1 in Tangier disease. J Clin Invest. 1995;96:78-87.
12. Schmitz G, Fischer H, Beuck M, Hoecker K-D, Robenek H. Dysregulation of lipid metabolism in Tangier monocyte-derived macrophages. Arteriosclerosis 1982;10:1010-1019.
13. Jackson RL, Gotto AM, Stein O, Stein Y. A comparative study on the removal of cellular lipids form Landschutz ascites cells by human plasma apolipoproteins. J Biol Chem. 1975;250:7204-7209.
14. Hara H, Yokoyama S. Infraction of free apolipoproteins with macrophages. J Biol Chem. 1991; 266:3080-3086.
15. Forte TM, Bielicki JK, Goth-Goldstein R, Selmer J, Mcall MR. Recruitment of cell phospholipids and cholesterol by apolipoproteins A-II and A-I: formation of nascent apolipoproteins-specific HDL that differ in size, phospholipid composition, and reactivity with LCAT. J Lipid Res. 1995;36:148-157.
16. Forte TM, Goth-Goldstein R, Nordhausen RW, Mcall MR. Apolipoprotein A-I cell membrane interaction: extracellular assembly of heterogeneous nascent HDL particles. J Lipid Res. 1993;34:317-324.
17. Hara H, Hara H, Komaba A, Yokoyama S. Alpha-helical requirements for free apolipoproteins to generate HDL and to induce cellular lipid efflux. Lipids. 1992;27:302-304.
18. Bielicki JK, Johnson WJ, Weinberg RB, Glick JM, Rothblat GH. Efflux of lipid from fibroblasts to apolipoproteins: dependence on elevated levels of cellular unesterified cholesterol. J Lipid Res. 1992;33:1699-1709.
19. Neary RH, Gowland E. Stability of free apolipoprotein A-I concentration in serum, and its measurements in normal and hyperlipidemic subjects. Clin Chem. 1987;33:1163-1169.