Genomic analysis highlights the role of the JAK-STAT signaling in the anti-proliferative effects of dietary flavonoid'ashwagandha' in prostate cancer cells

Evidence-based Complementary and Alternative Medicine

Volumn 7, Issue 2, 2010, Pages 177-187

  Aalinkeel, Ravikumar ^a   Hu, Zihua ^b   Nair, Bindukumar B ^a   Sykes, Donald E ^a   Reynolds, Jessica L ^a   Mahajan, Supriya D ^a   Schwartz, Stanley A ^a  

^a BUFFALO GENERAL HOSPITAL   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

Ashwagandha; Bioflavonoids; Genomics; Immunomodulation; Microarrays; Prostate cancer; Signal transduction

Indexed keywords

ANTINEOPLASTIC AGENT; BIOFLAVONOID; CASPASE 6; CYCLIN D; FAS ASSOCIATED DEATH DOMAIN PROTEIN; HEAT SHOCK PROTEIN 70; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; STAT2 PROTEIN;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL; CANCER GROWTH; CELL CYCLE REGULATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; GENE EXPRESSION; GENOME ANALYSIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; MALE; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; ONCOGENE C MYC; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING; WITHANIA SOMNIFERA;

EID: 77952214542     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/nem184     Document Type: Article

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